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Alpha Star Aviation Services, Riyadh RIYADH Saudi Arabia

Saudi Aramco A Fully Integrated Global Petroleum And Chemicals Enterprise Is The State Owned Oil Company Of The Kingdom Of Sa... Awad Basahi, Riyadh, RIYADH, Saudi Arabia




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Aviation Australia Riyadh College, Riyadh Riyadh Saudi Arabia

International Aviation Technical College At Riyadh International Aviation Technical College At Riyadh Provides World Class Aviat... Abdelelah Alsaad, Riyadh, Riyadh, Saudi Arabia




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PERSIAN AMBITIONS

PERSIAN AMBITIONS



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107: Parthian king Xosroes Murders Second Bishop of Arbela

107: Parthian king Xosroes Murders Second Bishop of Arbela



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1831-1937: Sayfo (Assyrian Genocide, in Arabic)

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Sustainability through optimising user interactions within the transport domain

Sustainability Through Optimising User Interactions Within The Transport Domain

Emma Foster...





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Oa Cabin Services Agent

Orlando, FL United States Description Great News! Want to work for one of the leading fueling companies in the world? Join Menzies Aviation and be part of our family! As a member of our cabin cleaning team you will be responsible for the safe and efficient cleaning of aircraft cabins. Some of the duties will include preparing cleaning solvents for use vacuuming sweeping dusting and disinfecting the aircraft cabin. Cleaning solvents need to be stored correctly after use and all soiled linens deposited into laundry bins. You will be driving and operating small specialized commercial vehicles at times and as such you will require a valid driver’s license with a clean driving record. You and your team will be required to maintain a safe and secure work environment in accordance with local health safety and security policies and pro




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Cabin Service Agent

Ft Lauderdale, FL United States Description Great News! Want to work for one of the leading fueling companies in the world? Join Menzies Aviation and be part of our family! Key Responsibilities + Remove blankets and pillows and replace them with clean ones + Ensure all cleaning solvents are stored correctly after use + Ensure that all cleaning equipment is in working order and that all protective clothing is worn as instructed + Deposit all soiled linens into laundry bins + Adhere to Menzies uniform guidelines and code of conduct + Operate small specialized commercial vehicles + Maintain a safe and secure work environment in accordance with local health safety and security policies and procedures + Other duties as assigned Qualifications + Must be 18 years of age or older + Possess and maintain a valid US drivers license + Must be able to




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English-Assyrian-Arabic Dictionary Volumes I and II

English-Assyrian-Arabic Dictionary Volumes I and II




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The "Gutenberg Bible" of Modern Syriac

The "Gutenberg Bible" of Modern Syriac




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[Swedish] Jakobiter - Vilka är de? Del I.

[Swedish] Jakobiter - Vilka är de? Del I.




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[Swedish] Jakobiter - Vilka är de? Del II.

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[Swedish] Jakobiter - Vilka är de? Del III.

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[Swedish] Jakobiter - Vilka är de? Del IV.

[Swedish] Jakobiter - Vilka är de? Del IV.




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1,500-year-old handwritten Bible kept in Ankara, ministry co...

1,500-year-old handwritten Bible kept in Ankara, ministry confirms




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Pakistan: Flag burning big business (Mar Kh’nanya Dinkha IV ...

Pakistan: Flag burning big business (Mar Kh’nanya Dinkha IV photo burned)




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WikiLeaks: 2010-02-28: 10BAGHDAD523: PRT Ninewa: Archbishop ...

WikiLeaks: 2010-02-28: 10BAGHDAD523: PRT Ninewa: Archbishop of Ninewa Describes Climate of Fear




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Gishru, Birthright Assyria (2012, presentation)

Gishru, Birthright Assyria (2012, presentation)



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Lorenzo Lamas to Star in upcoming Biblical Film Epic

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New Maryland program to help residents with water bill debt

(The Center Square) – The state of Maryland is investing $20 million in taxpayer fudning into the Water Assistance Relief Program to support those residents with water bill debt that is directly related to the COVID-19 pandemic, Gov. Larry Hogan said.




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Los Angeles, Cook counties post biggest population losses in U.S. in 2022

(The Center Square) – The number of people who used to live in Los Angeles County and Cook County in Illinois continues to plummet.




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Cabin Service Supervisor

Ft Lauderdale, FL United States - Description Key Responsibilities • Oversee and direct the basic and deep cleaning functions of all assigned commercial aircraft thoroughly and efficiently.• Mentor coach train and direct agents and leads.• Ensure preparation of all clea... View




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Cabin Service Supervisor

Ft Lauderdale, FL United States - Description Key Responsibilities • Oversee and direct the basic and deep cleaning functions of all assigned commercial aircraft thoroughly and efficiently.• Mentor coach train and direct agents and leads.• Ensure preparation of all clea... View




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Cabinet Finisher II

Savannah, GA United States - High School Diploma or GED required. Two (2) years experience in wood finishing. Experience in aerospace industry preferred. Basic knowledge of cabinet finishing processes and products. Position Purpose: Under general supervision, prepares and applies finishes to aircr... View




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Co-op: We have ambitious goals for the continued growth of our ecommerce business

 Co-op today announces expanded access to its own online shop, accessed via the Co-op app, through a new partnership with Uber Direct, Uber’s white-label delivery solution.




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shöpping: with our expansion into Germany, we kill two birds with one stone.

shöpping, the online marketplace of Austrian Post, is taking the next step in growth and expanding into Germany.




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Stuart and Nash platforms integrate to give businesses “full visibility and control over the delivery process”

Last-mile tech logistics specialist Stuart announced a new partnership with delivery orchestration platform, Nash. This collaboration will support merchants across restaurants, grocery, retail, and e-commerce to optimise local delivery operations and accelerate growth. 




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IKEA: Partnering with Australia’s largest delivery provider allows us to enhance our accessibility

Australia Post and IKEA have today announced a new strategic partnership, entering into a three-year agreement to further expand IKEA’s delivery footprint in Australia.




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GLS “to offer SMEs greater visibility and growth opportunities”

Polish marketplace ERLI, has partnered with DPD Poland,  expanding ERLI's Delivery Methods offer. 




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Automated Passport Control Ambassador Bilingual English spanish

Bwi Airport, MD United States - Description ESSENTIAL DUTIES AND RESPONSIBILITIES + Location: Baltimore International Airport + Rate of Pay: $15.00 per hour + Schedule: 1:30pm - 9:00pm must work weekends and holidays + Training: Monday - Friday 9:00am - 3:30pm Planning organizing coordinating and d... View




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Cabinet Finisher II

Savannah, GA United States - High School Diploma or GED required. Two (2) years experience in wood finishing. Experience in aerospace industry preferred. Basic knowledge of cabinet finishing processes and products. Position Purpose: Under general supervision, prepares and applies finishes ... View




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RS Cabinet Marker II

Dallas, TX United States - High School Diploma or GED required. Basic knowledge of cabinetmaking processes, products and tools. Two (2) years experience in cabinetmaking. Experience in aerospace industry preferred. Possess a working knowledge of company inspection and process specifications prefer... View




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Cabinet Maker II

Savannah, GA United States - High School Diploma or GED required. Basic knowledge of cabinetmaking processes, products and tools. Two (2) years experience in cabinetmaking. Experience in aerospace industry preferred. Possess a working knowledge of company inspection and process specifications pref... View




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Cabinet Maker I

Savannah, GA United States - High School Diploma or GED required. Wood working, wood finishing or auto body & painting experience in a technical environment or completion of Technical Certificate in cabinet making preferred and/or completion in current year youth apprenticeship program, in... View




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Hamilton County court: 6 Frisch's big Boys closing Tuesday




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Billionaires Are Piling Into an Index Fund That Could Soar Up to 1,207% by 2030, According to Wall Street Experts




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Bituminous sands of northern Alberta Township 92 ranges 9.10 and E1/2 11 Township 93 ranges 9.10 and E1/2 11

Re-release; Canada Mines Branch. 636, 1925, 1 sheet, https://doi.org/10.4095/307817
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/cmb_636.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/cmb_636.jpg" title="636, 1925, 1 sheet, https://doi.org/10.4095/307817" height="150" border="1" /></a>




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Beehive Mountain, Alberta and British Columbia, 82j/2 e1/2

Re-release; Norris, D K. no. 58-5, 1958, 25 pages (1 sheet), https://doi.org/10.4095/101214




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Fernie map-area, east half, Alberta and British Columbia, 82G E1/2

Re-release; Price, R A. 61-24, 1962, 65 pages (1 sheet), https://doi.org/10.4095/101249




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Geology of Terrace map-area, British Columbia (103 I E1/2)

Re-release; Duffell, S; Souther, J G. 329, 1964, 131 pages (3 sheets), https://doi.org/10.4095/100553




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Geology of Fort Grahame E1/2 map-area, British Columbia

Re-release; Gabrielse, H. 75-33, 1975, 28 pages (2 sheets), https://doi.org/10.4095/102605




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Biden's embrace of Saudi prince shows that his only principle was defeating Trump

At this point, it may be fair to say President Joe Biden’s criticisms of his predecessor have nothing to do with principles. It was all politics, all the way down.




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The Biology Of Why Coronavirus Is So Deadly

The Biology Of Why Coronavirus Is So Deadly

COVID-19 is caused by a coronavirus called SARS-CoV-2. Coronaviruses belong to a group of viruses that infect animals, from peacocks to whales. They’re named for the bulb-tipped spikes that project from the virus’s surface and give the appearance of a corona surrounding it.

A coronavirus infection usually plays out one of two ways: as an infection in the lungs that includes some cases of what people would call the common cold, or as an infection in the gut that causes diarrhea. COVID-19 starts out in the lungs like the common cold coronaviruses, but then causes havoc with the immune system that can lead to long-term lung damage or death.

SARS-CoV-2 is genetically very similar to other human respiratory coronaviruses, including SARS-CoV and MERS-CoV. However, the subtle genetic differences translate to significant differences in how readily a coronavirus infects people and how it makes them sick.

 

SARS-CoV-2 virus particles (pink dots) on a dying cell. National Institute of Allergy and Infectious Diseases, NIH

 

SARS-CoV-2 has all the same genetic equipment as the original SARS-CoV, which caused a global outbreak in 2003, but with around 6,000 mutations sprinkled around in the usual places where coronaviruses change. Think whole milk versus skim milk.

Compared to other human coronaviruses like MERS-CoV, which emerged in the Middle East in 2012, the new virus has customized versions of the same general equipment for invading cells and copying itself. However, SARS-CoV-2 has a totally different set of genes called accessories, which give this new virus a little advantage in specific situations. For example, MERS has a particular protein that shuts down a cell’s ability to sound the alarm about a viral intruder. SARS-CoV-2 has an unrelated gene with an as-yet unknown function in that position in its genome. Think cow milk versus almond milk.

 

How the virus infects

 

Every coronavirus infection starts with a virus particle, a spherical shell that protects a single long string of genetic material and inserts it into a human cell. The genetic material instructs the cell to make around 30 different parts of the virus, allowing the virus to reproduce. The cells that SARS-CoV-2 prefers to infect have a protein called ACE2 on the outside that is important for regulating blood pressure.

The infection begins when the long spike proteins that protrude from the virus particle latch on to the cell’s ACE2 protein. From that point, the spike transforms, unfolding and refolding itself using coiled spring-like parts that start out buried at the core of the spike. The reconfigured spike hooks into the cell and crashes the virus particle and cell together. This forms a channel where the string of viral genetic material can snake its way into the unsuspecting cell.

An illustration of the SARS-CoV-2 spike protein shown from the side (left) and top. The protein latches onto human lung cells. 5-HT2AR/Wikimedia

SARS-CoV-2 spreads from person to person by close contact. The Shincheonji Church outbreak in South Korea in February provides a good demonstration of how and how quickly SARS-CoV-2 spreads. It seems one or two people with the virus sat face to face very close to uninfected people for several minutes at a time in a crowded room. Within two weeks, several thousand people in the country were infected, and more than half of the infections at that point were attributable to the church. The outbreak got to a fast start because public health authorities were unaware of the potential outbreak and were not testing widely at that stage. Since then, authorities have worked hard and the number of new cases in South Korea has been falling steadily.

 

How the virus makes people sick

 

SARS-CoV-2 grows in type II lung cells, which secrete a soap-like substance that helps air slip deep into the lungs, and in cells lining the throat. As with SARS, most of the damage in COVID-19, the illness caused by the new coronavirus, is caused by the immune system carrying out a scorched earth defense to stop the virus from spreading. Millions of cells from the immune system invade the infected lung tissue and cause massive amounts of damage in the process of cleaning out the virus and any infected cells.

Each COVID-19 lesion ranges from the size of a grape to the size of a grapefruit. The challenge for health care workers treating patients is to support the body and keep the blood oxygenated while the lung is repairing itself.

 

How SARS-CoV-2 infects, sickens and kills people

 

SARS-CoV-2 has a sliding scale of severity. Patients under age 10 seem to clear the virus easily, most people under 40 seem to bounce back quickly, but older people suffer from increasingly severe COVID-19. The ACE2 protein that SARS-CoV-2 uses as a door to enter cells is also important for regulating blood pressure, and it does not do its job when the virus gets there first. This is one reason COVID-19 is more severe in people with high blood pressure.

SARS-CoV-2 is more severe than seasonal influenza in part because it has many more ways to stop cells from calling out to the immune system for help. For example, one way that cells try to respond to infection is by making interferon, the alarm signaling protein. SARS-CoV-2 blocks this by a combination of camouflage, snipping off protein markers from the cell that serve as distress beacons and finally shredding any anti-viral instructions that the cell makes before they can be used. As a result, COVID-19 can fester for a month, causing a little damage each day, while most people get over a case of the flu in less than a week.

At present, the transmission rate of SARS-CoV-2 is a little higher than that of the pandemic 2009 H1N1 influenza virus, but SARS-CoV-2 is at least 10 times as deadly. From the data that is available now, COVID-19 seems a lot like severe acute respiratory syndrome (SARS), though it’s less likely than SARS to be severe.

 

What isn’t known

 

There are still many mysteries about this virus and coronaviruses in general – the nuances of how they cause disease, the way they interact with proteins inside the cell, the structure of the proteins that form new viruses and how some of the basic virus-copying machinery works.

Another unknown is how COVID-19 will respond to changes in the seasons. The flu tends to follow cold weather, both in the northern and southern hemispheres. Some other human coronaviruses spread at a low level year-round, but then seem to peak in the spring. But nobody really knows for sure why these viruses vary with the seasons.

What is amazing so far in this outbreak is all the good science that has come out so quickly. The research community learned about structures of the virus spike protein and the ACE2 protein with part of the spike protein attached just a little over a month after the genetic sequence became available. I spent my first 20 or so years working on coronaviruses without the benefit of either. This bodes well for better understanding, preventing and treating COVID-19.

By Benjamin Neuman, Professor of Biology, Texas A&M University-Texarkana. This article is republished from The Conversation under a Creative Commons license. Read the original article.

The Conversation Thu, 04/02/2020 - 14:02
Categories




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Home economics: High housing costs may haunt Biden on the 2024 campaign trail

Mortgage rates are at their highest levels in 22 years and house prices are at record highs. Hardworking Americans cannot get on the property ladder, and retirees are struggling to sell in order to downsize. The Biden administration has done little to help alleviate the problem. This Washington Examiner series, Home Economics, will investigate how we got here, the toll on people around the country, and the alternatives people are embracing to survive the market. Part one of this four-part series focuses on the risk the crisis poses to President Joe Biden's reelection effort.




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Home economics: The human cost of the affordability crisis

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Hospitals that pursue patients for unpaid bills will have to tell L.A. County

Hospitals must promptly report to the Los Angeles County public health department each time they try to collect medical debt from patients, under an ordinance backed Tuesday by county supervisors.




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Power-hungry AI data centers are raising electric bills and blackout risk

Experts warn that a frenzy of data center construction could delay California's transition away from fossil fuels, raise electric bills and increase risk of blackouts