rna Post-crisis international financial regulatory reforms: a primer By www.bis.org Published On :: 2020-04-23T16:00:00Z This paper reviews post-crisis financial regulatory reforms, examines how they fit together and identifies open issues. Specifically, it takes stock of the salient new features of bank and CCP international standards within a unified analytical framework. Full Article
rna Dollar invoicing, global value chains, and the business cycle dynamics of international trade By www.bis.org Published On :: 2020-04-28T09:00:00Z Recent literature has highlighted that international trade is mostly priced in a few key vehicle currencies, and is increasingly dominated by intermediate goods and global value chains (GVCs). Taking these features into account, this paper reexamines the business cycle dynamics of international trade and its relationship with monetary policy and exchange rates. Full Article
rna No global real estate market despite higher price synchronisation and growing role of international investors, central banks find By www.bis.org Published On :: 2020-02-18T12:00:00Z No global real estate market despite higher price synchronisation and growing role of international investors, central banks find (Press release, 18 February 2020) Full Article
rna Saudi G20 Presidency and the Bank for International Settlements (BIS) Innovation Hub invite global innovators to find solutions to the most pressing financial regulatory & supervisory challenges By www.bis.org Published On :: 2020-04-29T08:00:00Z Press release "Saudi G20 Presidency and the Bank for International Settlements (BIS) Innovation Hub invite global innovators to solve RegTech and SupTech challenges", 27 April 2020 Full Article
rna International Art Project Seeks To Transform Flint's Image By www.wkar.org Published On :: Fri, 31 May 2019 18:16:52 +0000 Artists from Michigan and around the world are painting 50 murals in Flint to refocus the city's image on art rather than the lead-tainted water crisis. Full Article
rna BIS international banking statistics at end-September 2019 By www.bis.org Published On :: 2020-01-22T09:00:00Z Global cross-border bank claims continued to expand rapidly, growing at 9% year on year. As in previous quarters, the expansion was mainly due to claims on the non-bank sector, which grew at 12% year on year. The growth in claims on non-bank financial institutions was particularly strong (+17%). European banks' cross-border lending, which went through a prolonged contraction after the Great Financial Crisis (GFC) of 2007-09, has been expanding again since the start of 2018. Full Article
rna BIS international banking statistics at end-December 2019 By www.bis.org Published On :: 2020-04-22T08:00:00Z The annual growth rate of global cross-border bank claims fell to 6%, down from 9% at end-September 2019. The short-term share of foreign banks' claims, a key indicator of external vulnerability, is elevated for a number of borrowing emerging market and developing economies (EMDEs). Borrowers in EMDEs had untapped credit lines of $610 billion, or roughly 10% of the stock of global foreign claims on EMDEs at end-2019. Saudi Arabia joined the reporting population for the locational banking statistics (LBS) with data starting from Q4 2017, bringing the number of countries reporting these data to 48. Full Article
rna International restrictions pose a challenge for resuming pro sports By www.cbc.ca Published On :: Wed, 29 Apr 2020 22:33:20 EDT As the NHL, NBA and MLB consider resuming play, the issue of international travel poses another hurdle for Canadian-based teams. Full Article Sports
rna The Scene – Akron Beacon Journal By rss-newsfeed.india-meets-classic.net Published On :: Fri, 08 May 2020 18:02:27 +0000 The Scene Akron Beacon Journal Full Article IMC News Feed
rna Salman Khan shoots song titled ‘Tere Bina’ with Jacqueline Fernandez at his Panvel farmhouse; reveals det – NewsEverything By rss-newsfeed.india-meets-classic.net Published On :: Fri, 08 May 2020 22:55:16 +0000 Salman Khan shoots song titled 'Tere Bina' with Jacqueline Fernandez at his Panvel farmhouse; reveals det NewsEverythingSalman Khan and Jacqueline Fernandez get candid about upcoming song Tere Bina; Watch VIDEO PINKVILLASalman Khan’s ladylove Iulia Vantur feels he looks like a “Supermodel” in his latest picture with Niketan Times of IndiaIulia Vantur asked when she is marrying Salman Khan, says ‘spending your life with someone’ more important... Hindustan TimesSalman Khan's caravan Being Haangryy provides essentials to needy people of Mumbai Bollywood LifeView Full coverage on Google News Full Article IMC News Feed
rna Canadian Duvernay-Tardif reworks contract to give NFL's Chiefs cap space By www.cbc.ca Published On :: Thu, 23 Apr 2020 12:38:37 EDT Laurent Duvernay-Tardif and the Kansas City Chiefs have agreed to a restructured deal for the Canadian offensive lineman. Full Article Sports/Football/NFL
rna Canadian NFLer Duvernay-Tardif joining medical front line in Quebec By www.cbc.ca Published On :: Mon, 27 Apr 2020 15:43:41 EDT A Quebec-born Super Bowl champion is making the move from the offensive line to the medical front line. Full Article Sports/Football/NFL
rna On the road throughout Europe - International By feedproxy.google.com Published On :: Thu, 24 Sep 2015 00:00:00 +0000 Throughout the year Bus4Life provides encouragement to local pastors and OM teams in Eastern Europe, partnering with them to share the Gospel. Full Article
rna CME Group Achieves Record International Average Daily Volume of 7.2 Million Contracts in Q1 2020, Up 57 Percent from Q1 2019 By feedproxy.google.com Published On :: 2020-04-08T07:01:01Z Full Article
rna Quantifying and Storing RNA By cshprotocols.cshlp.org Published On :: 2020-03-02T06:30:09-08:00 Quantifying RNA is an important and necessary step before most RNA analysis techniques. Methods for quantifying RNA can be classified into two categories: ultraviolet (UV) spectrophotometric methods, which are based on the absorption spectra of the purine and pyrimidine bases; and fluorescent dye-based methods, which measure the fluorescence intensity of dyes that selectively fluoresce when bound to nucleic acids. If the RNA sample is pure (i.e., without significant amounts of contaminants such as proteins, phenol, agarose, or other nucleic acids), UV spectrophotometric measurement of the amount of UV irradiation absorbed by the bases is simple and accurate. However, if the sample contains significant quantities of impurities or if the concentration of RNA is very low, it is better to use fluorescent dye-based methods. An overview of spectrophotometric and fluorescent dye-based RNA quantification methods is given here, as are several options for storing purified RNA preparations. Proper storage of RNA samples is important; it can help minimize RNase contamination and consequent sample degradation. Full Article
rna Dollar invoicing, global value chains, and the business cycle dynamics of international trade By www.bis.org Published On :: 2020-04-01T00:00:00Z Bank for International Settlements BIS Working Papers by David Cook and Nikhil Patel Full Article
rna Post-crisis international financial regulatory reforms: a primer By www.bis.org Published On :: 2020-04-01T00:00:00Z Bank for International Settlements BIS Working Papers by Claudio Borio, Marc Farag and Nikola Tarashev Full Article
rna International and domestic interactions of macroprudential and monetary policies: the case of Chile By si2.bcentral.cl Published On :: 2020-04-01T00:00:00Z Central Bank of Chile Working Papers by Tomás Gómez, Alejandro Jara and David Moreno Full Article
rna Optional alternative grading scale implemented for spring 2020 semester By news.psu.edu Published On :: Wed, 25 Mar 2020 17:41 -0400 Penn State is implementing a new opt-in grading system for the spring 2020 semester that will give students flexibility, help preserve GPAs and minimize impacts to students’ transcripts during the academic challenges presented by the novel coronavirus public health crisis. Full Article
rna Der Weg zu widerstandsfähigem Wachstum führt über internationale Zusammenarbeit By www.bis.org Published On :: 2017-06-25T10:30:00Z German translation of the BIS Press Release on the presentation of the Annual Report (25 June 2017) Full Article
rna BIZ-Quartalsbericht September 2017: Verbesserte Aussichten und niedrige Inflation beleben die Risikoübernahme By www.bis.org Published On :: 2017-09-17T16:00:00Z German translation of the BIS press release about the BIS Quarterly Review, September 2017 Full Article
rna Zimbabwe: Time for International Action By feedproxy.google.com Published On :: Thu, 11 Oct 2001 22:00:00 GMT Full Article
rna All Bark and No Bite? The International Response to Zimbabwe's Crisis By feedproxy.google.com Published On :: Thu, 24 Jan 2002 23:00:00 GMT Full Article
rna Zimbabwe: The Politics of National Liberation and International Division By feedproxy.google.com Published On :: Wed, 16 Oct 2002 22:00:00 GMT Full Article
rna Homeless people find their eternal home By feedproxy.google.com Published On :: Fri, 25 May 2018 00:00:00 +0000 Veracruz, Mexico :: A team from Logos Hope points homeless people to Christ at a church outreach. Full Article
rna Vatican urges Catholics to reach out to internally displaced people By feedproxy.google.com Published On :: Tue, 05 May 2020 08:10:00 -0600 Vatican City, May 5, 2020 / 08:10 am (CNA).- The Vatican’s migrant and refugee office has released a booklet with guidance on how the Church might respond to the problem of people internally displaced within their own countries due to conflict or disaster. Many people might be unaware of the existence of internally displaced people, or IDPs, Cardinal Michael Czerny, under-secretary of the migrants and refugees section, said May 5. Speaking during a livestreamed press conference, he noted that internal displacement “is a current, contemporary reality in a surprising number of countries.” Internally displaced persons are defined as those who have had to flee their home or residence due to violence, conflict, disaster, or development projects to find refuge in another part of the country. Since IDPs have not crossed international borders, they do not have the legal status of refugee or migrant and do not receive the legal protections those categories can give. Czerny’s office, which is a part of the Dicastery for Promoting Integral Development, published a booklet May 5 called “Pastoral Orientations on Internally Displaced People.” The document is directed primarily at dioceses, parishes, Catholic NGOs, and other Catholic organizations. It has short paragraphs on key issues related to the welcome, protection, promotion, and integration of IDPs, interspersed with quotes from relevant Church documents and speeches by Pope Francis. The importance of spiritual care for Catholics who are internally displaced in their countries is one of the topics addressed. Cardinal Czerny said Tuesday he would like to highlight the response an average Catholic parish might give when it “discovers IDPs in its midst and learns how to reach out to them.” “To me, this is a great sign of hope,” he said. “When the Holy Father asks us to go to the peripheries, we might think of going to a faraway foreign land where we will do exotic things,” the cardinal said. “But the real peripheries which hurt are the ones that are very near at hand, the ones where people among us are invisible, are set aside, are discarded, are overlooked.” According to data from the Internal Displacement Monitoring Centre (IDMC), at the end of 2019, 45.7 million people were living internally displaced from their homes worldwide for reasons of conflict. Including other causes of displacement, the number of IDPs is more than 50 million. The IDMC reported that the countries with the highest numbers of internally displaced people are Syria, Democratic Republic of Congo, Afghanistan, Iraq, Yemen, and Colombia, though nearly every country in the world has IDPs. In the United States, the IDMC says there were 916,000 people newly displaced internally due to disaster in 2019. The majority of these new displacements were caused by Hurricane Dorian and the California wildfires. The Church can do something so that “those among us who have been forced to flee and find themselves among us will receive Christian welcome and the response the Body of Christ wants to give them,” Czerny explained. He said the aim of “Pastoral Orientations” is for the more than 50 million IDPs “to be recognized and supported, promoted and eventually reintegrated, so that they can play an active, constructive role in their country even if powerful causes, both natural and unjust human causes, have forced them to flee from home and take refuge somewhere.” “In the post-COVID-19 world that is emerging, their contribution will be very much needed,” the cardinal added. He explained that publishing the document on internal displacement is “not a lessening on the priority of refugees, migrants, asylum seekers, victims of human trafficking,” but a matter of “continuing to respond to the full range of people’s needs and vulnerabilities,” even in the midst of a global pandemic. “There are very many needs which didn’t go away just because we were focused on other things in the past weeks,” he underlined. “It’s not a question of COVID-19 displacing priorities. It’s a question of both/and…” Problems such as internal displacement were already there, “and, on top of it all we also have the challenge as a human family of resisting and overcoming this pandemic.” The Church, he said, is able “to take on a new challenge without jettisoning other problems as if they suddenly became irrelevant.” Full Article Vatican
rna Maternal and Child Health Bureaus Autism Research Program By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:42-07:00 OBJECTIVES: To provide an overview and quantitatively demonstrate the reach of the Health Resources and Services Administration’s Maternal and Child Health Bureau autism research program. METHODS: We reviewed program reports and internal data from 59 autism research grantees. The US federal Interagency Autism Coordinating Committee’s strategic plan questions were used as a framework to highlight the contributions of the autism research program in advancing the field. RESULTS: The autism research program grantees advance research in several ways. Grantees have strengthened the evidence for autism interventions by conducting 89 studies at 79 distinct research sites. A total of 212 708 participants have enrolled in autism research program studies and 361 researchers have contributed to furthering autism research. The program addresses topics that align with the majority of the Interagency Autism Coordinating Committee’s priority topic areas, including advancements in treatments and interventions, services and supports, and identifying risk factors. Grantee products include 387 peer-reviewed publications, 19 tools, and 13 practice guidelines for improving care and intervention practices. CONCLUSIONS: The autism research program has contributed to medical advances in research, leveraged innovative training platforms to provide specialized training, and provided access to health services through research-based screening and diagnostic procedures. Autism research program studies have contributed to the development of evidence-based practice guidelines, informed policy guidelines, and quality improvement efforts to bolster advancements in the field. Although disparities still exist, the Health Resources and Services Administration’s Maternal and Child Health Bureau can reduce gaps in screening and diagnosis by targeting interventions to underserved populations including minority and rural communities. Full Article
rna Fin24.com | The appeal of alternatives By www.fin24.com Published On :: Fri, 27 Aug 2010 10:12:10 +0200 Investors like something different. Full Article
rna International with lots of charm By feedproxy.google.com Published On :: Fri, 25 May 2018 06:58:18 +0000 "The Lord gave me a verse out of Isaiah 50:5...I started to understand that I had a lot to give, and that God’s ways for me might lead me differently than I had thought," said OMer Evelyn. Full Article
rna Andy Murray signs up for virtual Madrid tennis tournament amid coronavirus crisis By www.heraldscotland.com Published On :: Fri, 10 Apr 2020 09:56:40 +0100 ANDY MURRAY will swap a tennis racket for a games controller when he takes part in a virtual Madrid Open later this month. Full Article
rna Development tournament played in Nyon By www.uefa.com Published On :: Wed, 18 Apr 2012 08:27:00 GMT Women's Under-17 teams gathered in Nyon for a friendly tournament this week, with associations welcoming UEFA's drive to give young players chances for further development. Full Article HatTrick
rna Tenth UEFA Regions' Cup: final tournament draw By www.uefa.com Published On :: Thu, 02 Mar 2017 14:45:00 GMT Hosts Istanbul must face qualifying stars Zagreb in the group stage following the draw for the tenth UEFA Regions' Cup finals, with former winners Castilla y León in the other section. Full Article general
rna Development tournament season under way By www.uefa.com Published On :: Sun, 22 Feb 2015 12:49:00 GMT With a busy season ahead, involving all 54 member associations, the latest round of UEFA development tournaments for Under-16 national sides are under way, starting in the Algarve. Full Article elite youth develop
rna Boquete backs Croatia tournament By www.uefa.com Published On :: Tue, 10 Mar 2015 17:38:00 GMT Spain forward and UEFA ambassador Verónica Boquete was on hand at the women's Under-16 development tournament in Zagreb to support Croatia's promotion of the female game. Full Article wf programme
rna Maternal Resolution of Grief After Preterm Birth: Implications for Infant Attachment Security By pediatrics.aappublications.org Published On :: 2011-01-31T04:00:54-08:00 For mothers of children with chronic medical conditions or disabilities, such as epilepsy or cerebral palsy, a history of maternal unresolved grief regarding the child's diagnosis has been associated with insecure infant-mother attachment. Unresolved grief related to a preterm birth is associated with the development of insecure infantmother attachment. Mothers with resolved grief after preterm birth are 2.9 times as likely to have securely attached infants, compared with mothers with unresolved grief. (Read the full article) Full Article
rna Quality of Early Maternal-Child Relationship and Risk of Adolescent Obesity By pediatrics.aappublications.org Published On :: 2011-12-26T00:06:35-08:00 The quality of the relationship between mother and child affects the child’s neurodevelopment, emotion regulation, and stress response. Extreme or sustained stress responses are associated with dysregulation of physiologic systems involved in energy balance, which could lead to obesity.The prevalence of obesity in adolescence was more than twice as high among those youth who in early childhood had poor-quality relationships with their mothers compared with those with better relationships. (Read the full article) Full Article
rna Maternal Asthma Medication Use and the Risk of Selected Birth Defects By pediatrics.aappublications.org Published On :: 2012-01-16T00:06:51-08:00 Asthma is a common obstructive pulmonary disease experienced during pregnancy. Clinical guidelines recommend women with asthma maintain asthma medication use during pregnancy. Epidemiologic studies suggest an association between several types of defects and asthma or asthma medication use during pregnancy.Data from a large, population-based, multicenter, case-control study was used. This provides the opportunity to study specific birth defects with minimal heterogeneity in case groups, as well as control for a variety of potential confounders. (Read the full article) Full Article
rna Fetal and Maternal Candidate Single Nucleotide Polymorphism Associations With Cerebral Palsy: A Case-Control Study By pediatrics.aappublications.org Published On :: 2012-01-30T00:06:43-08:00 Candidate genes involved in thrombophilia, inflammation, and preterm birth have previously been associated with cerebral palsy. Most studies to date have included small cohorts, did not allow for multiple testing, and require replication.This study of children with cerebral palsy and their mothers did not confirm previously reported candidate gene associations. Prothrombin gene mutation was associated with hemiplegia in children born at term to mothers with a reported infection during pregnancy. (Read the full article) Full Article
rna Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive Development By pediatrics.aappublications.org Published On :: 2012-02-13T00:08:33-08:00 Vitamin D levels in the general population have decreased considerably over the past decade. The implications of maternal vitamin D insufficiency during pregnancy for offspring neurocognitive development remain unclear.Studying a large sample and using a prospective longitudinal design, this study demonstrates a link between maternal vitamin D insufficiency during pregnancy and offspring language impairment. There was no association with childhood behavioral or emotional problems. (Read the full article) Full Article
rna Effect on Infant Illness of Maternal Supplementation With 400 000 IU Vs 200 000 IU of Vitamin A By pediatrics.aappublications.org Published On :: 2012-03-12T00:07:20-07:00 Postpartum vitamin A supplementation is a strategy to combat vitamin A deficiency and seems to reduce maternal/infant morbidity and mortality. However, controversies exist regarding which dose has a greater efficacy, 200 000 IU (WHO protocol) or 400 000 IU (IVACG protocol).In this study, postpartum maternal supplementation with 400 000 IU of vitamin A did not provide any additional beneficial effect in reducing infant morbidity compared with the standard dose of 200 000 IU. (Read the full article) Full Article
rna Relationship Between Maternal and Neonatal Staphylococcus aureus Colonization By pediatrics.aappublications.org Published On :: 2012-04-02T00:07:13-07:00 Staphylococcus aureus is a leading cause of infections in infants. Staphylococcal colonization is a known risk factor for infection, but whether maternal colonization plays a role in subsequent colonization in the infant is unclear.This prospective study found that infants born to women colonized with S aureus either during their third trimester of pregnancy or at the time of delivery are more likely to harbor S aureus than are those born to noncolonized women. (Read the full article) Full Article
rna Maternal Caffeine Consumption and Infant Nighttime Waking: Prospective Cohort Study By pediatrics.aappublications.org Published On :: 2012-04-02T00:07:11-07:00 Fetus and infants until 3 months of age are unable to metabolize caffeine, which crosses the placenta and in adults has a somnolytic effect. Little is known about the effect of caffeine consumption by pregnant or nursing mothers over infant sleeping.In this setting where caffeine is largely consumed in pregnancy and by nursing mothers, heavy consumption (≥300 mg/day) did not increase the number of nighttime awakenings by their 3-month-old infants. (Read the full article) Full Article
rna Complementary and Alternative Medicine Use and Adherence With Pediatric Asthma Treatment By pediatrics.aappublications.org Published On :: 2012-04-09T00:07:36-07:00 Complementary and alternative medicine (CAM) use for pediatric asthma is increasing. It is well known that effective asthma management depends on patient adherence to treatment. The authors of previous cross-sectional studies have linked CAM use with decreased adherence to conventional asthma treatment regimens.This longitudinal data set was unique, allowing us to focus on patients who initiated CAM and to follow subsequent asthma medication adherence. We found that CAM use was not associated with adherence, suggesting that patients may practice CAM alongside conventional therapies. (Read the full article) Full Article
rna Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders By pediatrics.aappublications.org Published On :: 2012-04-09T00:07:33-07:00 Diabetes during pregnancy has been associated with general development impairments in offspring; however, associations between autism and maternal diabetes have been inconsistent. Few studies have examined related conditions accompanied by underlying increased insulin resistance and their association with developmental outcomes.This population-based study in young children provides evidence that maternal metabolic conditions are a risk factor for autism, developmental delay without autistic symptoms, and impairments in several domains of development, particularly expressive language, after adjusting for sociodemographic and other characteristics. (Read the full article) Full Article
rna Long-term Effectiveness of Maternal Dietary Counseling in a Low-Income Population: A Randomized Field Trial By pediatrics.aappublications.org Published On :: 2012-05-07T00:07:49-07:00 Recent systematic reviews revealed that educational dietary interventions were effective in improving nutritional status and food consumption in the first year after birth. We are not aware, however, of studies in developing countries that have evaluated their long-term effectiveness.This randomized trial revealed that, in a low-income population, the delivery of home-based maternal counseling focusing on breastfeeding and complementary feeding during the first year of children’s lives significantly improved the lipid profile at 7 to 8 years old. (Read the full article) Full Article
rna Computer-Facilitated Substance Use Screening and Brief Advice for Teens in Primary Care: An International Trial By pediatrics.aappublications.org Published On :: 2012-05-07T00:07:47-07:00 Primary care settings provide an important venue for early detection of substance use and intervention, but adolescent screening rates need improvement. Screening and brief interventions appear effective in reducing adult problem drinking but evidence for effectiveness among adolescents is needed.A computer-facilitated system for screening, feedback, and provider brief advice for primary care can increase adolescent receipt of substance use screening across a variety of practice settings, and shows promise for reducing adolescents’ use of alcohol and cannabis. (Read the full article) Full Article
rna Infant Outcomes After Maternal Antiretroviral Exposure in Resource-Limited Settings By pediatrics.aappublications.org Published On :: 2012-05-14T00:07:41-07:00 Information on infant safety after exposure to maternal antiretroviral regimens during pregnancy in international clinical trials is lacking. As antiretroviral drugs are released to populations in resource-limited settings through clinical trials, it becomes critical to collect pediatric outcome data.The study demonstrates the feasibility of reporting infant outcomes following adult antiretroviral trials in developing countries, provides HIV-free infant survival and prospective growth data in association with maternal parameters, and details morbidity, mortality, and genetic defects following maternal antiretroviral exposure. (Read the full article) Full Article
rna Maternal Cigarette Smoking and the Development of Necrotizing Enterocolitis By pediatrics.aappublications.org Published On :: 2012-06-11T00:08:10-07:00 Fetal factors that predispose infants to necrotizing enterocolitis (NEC) have been extensively studied. Maternal factors that may affect future risk for NEC are less clear.We hypothesized that maternal factors were the primary cause of NEC. Through a case-control design we determined that maternal smoking predisposes infants to the development of NEC. Our results highlight the importance of smoking cessation in pregnancy. (Read the full article) Full Article
rna Frequency of Alternative Immunization Schedule Use in a Metropolitan Area By pediatrics.aappublications.org Published On :: 2012-06-18T00:07:29-07:00 Parents are increasingly following alternative immunization schedules. Current studies suggest up to 21% of parents in the United States are intentionally delaying or refusing some or all of the recommended early-childhood vaccines.This is the first study to use Immunization Information System data to quantify the proportion of children consistently delaying receipt of vaccines. Consistent-limiting children were found to have lower levels of recommended vaccines. (Read the full article) Full Article
rna Food Insecurity and Obesogenic Maternal Infant Feeding Styles and Practices in Low-Income Families By pediatrics.aappublications.org Published On :: 2012-07-23T00:07:48-07:00 Food insecurity has been linked to childhood obesity in a number of studies. Few studies have explored potential pathways through which food insecurity is related to child weight, especially in low-income families with young infants.We found that food insecurity was related to maternal controlling feeding styles and concerns about the infants’ future weight. Early obesity prevention should aim to decrease food insecurity and to reduce controlling feeding styles in families who remain food insecure. (Read the full article) Full Article