GLP issues raised by testing labs are covered in this comprehensive list of questions and answers, recently updated with questions related to: sponsors, Contract Research Organisations (CROs), sub-contractors, archives, Information Technology (IT), Biotechnology/GMOs and other miscellaneous issues

This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines.

Join us for our per- and polyfluoroalkyl substances webinar on Best Environmental Practices (BEP) for Textiles

This paper reviews and compares five case studies on quantification and economic valuation of benefits in cost-benefit analyses (CBAs) of regulating phthalates, mercury, PFOA (perfluoro-octanic acid) and its salts, NMP (1 methyl-2-pyrroloidine) and formaldehyde. The case studies had all been carried out as part of the SACAME project, and the purpose of the present paper is to draw out cross-cutting findings from these studies.

This document outlines various approaches and methodologies for the assessment of risks from combined exposures to multiple chemicals. The document draws from approaches and experience in the regulatory context, and presents elements to consider in the assessment.

The OECD releases a video tutorial on how to find GHS information in eChemPortal through the substance search and how to search by GHS classification. Currently 11 databases provide GHS information, independent of whether the classifications have undergone a review by a regulatory body or intergovernmental organisation or are based on self-classifications by the producers or importers.

This report outlines the customisation opportunities for IUCLID version 6. It also gives an overview of what IUCLID offers to regulatory bodies and industry as a key application to record, store, maintain and exchange data on chemicals. IUCLID is used in a variety of countries and regulatory contexts, therefore the report describes to which extent it is customisable to facilitate the management of chemical data across these contexts.

GHSTS is a standardised set of technical specifications for assembling electronic files for pesticide registration in a predefined manner. Once assembled according to the GHSTS, the dossier files can be transferred from a business to a regulatory authority and can be used in a regulatory process. Version 2.0 includes improved lifecycle management of documents over a series of submissions for one pesticide (or other) regulatory action.

Policy instruments can be applied to improve the sustainability of plastics, including regulations, market-based instruments, information and voluntary tools. The report reviews the use of these instruments, provides good practice examples, such as product taxes and charges, eco-design standards, extended producer responsibility and environmental product labels, as well as discussing opportunities for their future applications.

The purpose of this document is to give guidance to Receiving Authorities on the evaluation of the GLP compliance status of nonclinical safety studies submitted for regulatory purposes. This guidance does not address the scientific evaluation and interpretation of the submitted data or the risk assessment based on these data.

On Thursday 26 September 2019, the OECD discussed "Finding Alternatives to Per- and Polyfluoroalkyl Substances of Concern: A Difficult and Continuing Challenge" with the participation of W.L. Gore & Associates, Inc. Presenters shared efforts, successes and challenges in eliminating per and polyfluorinated chemicals of environmental concern from the life cycle of consumer products.

A major fruit crop of temperate regions, APPLE is consumed worldwide as fresh fruit, juice and other food products. This consensus document provides science-based key insights for the regulatory assessment of the environmental safety of genetically-engineered products: taxonomy, reproductive biology, genetics, hybridisation and introgression, and ecology.

The Chemical Safety and Biosafety Progress Report is released every eight months. Its purpose is to provide an update on the projects, events and activities. Information on new publications as well as dates and venues of upcoming events and meetings are given.

United States recorded 1347318 Coronavirus Cases since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 78616 Coronavirus Deaths. This page includes a chart with historical data for the United States Coronavirus Cases.

United States recorded 80040 Coronavirus Deaths since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 1347318 Coronavirus Cases. This page includes a chart with historical data for the United States Coronavirus Deaths.

United States recorded 238080 Coronavirus Recovered since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 80040 Coronavirus Deaths. This page includes a chart with historical data for the United States Coronavirus Recovered.

Paris is organised around culture to a degree unimaginable in mercantile, muddled-up London

Three recent decisions have brought this issue into focus – and all three are lamentable and incoherent

There are profound reasons for studying the languages, literature and civilisations of the Greeks and Romans

This is about reminding ourselves that we are animals, not adjuncts to computer terminals

It is that forging and tempering that makes the poet’s utterances strong and flexible

Through this column, connections have been made and the conversation has broadened

After 11 years, Harry Eyres’ column has come to an end. Here’s his first, from January 17, 2004

The taming of the Tea Party leaves the GOP short on the ideological message the voters like

All the world’s languages are anglicising and pidginising, but particularly French

Assertions the patient ‘wouldn’t have wanted to suffer’ offer doctors too much leeway

People do not want sweeping immigration reform. They want less immigration

The deal with Luxottica, worth €50bn, makes up for missed opportunities

With new owners, falling viewers and spiralling costs, Formula One is at a crossroads

The son of a towering industry figure is building his own empire

After a stormy summer, the chief is shaking up the world’s biggest shipping company

Can the sports car maker compete with Tesla as it moves into its territory?

After weathering the country’s worst recession, Candido Bracher is looking to expand

In a male-dominated industry, the executive says she has not been held back

Former head of UK Sport has set sights on winning the World Cup

Avoid eating too much and say yes to that extra glass of wine before you go to sleep in flight

The capital is the cleanest, most orderly and safest bet for spending time in a global city

A summer office set-up reminds us that we don’t need gimmicks in the workplace to keep colleagues happy

The great thing about many Alpine resorts is that they understand the value of leaving things alone

Your company secrets don’t need to be revealed to the tanning masses. Your shareholders will thank you

The Swiss bunker mentality has always felt at once quaint, menacing and oddly reassuring

While other countries spend a fortune attracting ‘influencers’, in Portugal it has happened organically

Toronto has a troubled history with its waterfront, much of which is cut off by an overhead expressway

Use your tax allowances to maximise the returns from your investments

Wine as an asset class is gaining credibility and many commentators cite recent demand from the Far East as the main driving force.

For investors tempted to put money into the stock market, there are some basic rules to consider

Tips on how to improve your retirement income

Kevin Lilley of Old Mutual picks out investment themes for the eurozone

Ten ways to improve your chances when placing a bet

Get your finances on track and prepare for the new year