Interview with Claudia S. Robertson, MD, author of Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury: A Randomized Clinical Trial

Interview with Nancy A. Rigotti, MD, author of Sustained Care Intervention and Postdischarge Smoking Cessation Among Hospitalized Adults

Interview with Irfan A. Dhalla, MD, MSc, author of Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients

Interview with Ziad Obermeyer, MD, MPhil, author of Association Between the Medicare Hospice Benefit and Health Care Utilization and Costs for Patients With Poor-Prognosis Cancer

Interview with Bradley M. Gray, PhD, author of Association Between Imposition of a Maintenance of Certification Requirement and Ambulatory Care-Sensitive Hospitalizations and Health Care Costs

Interview with Richard K. Burt, MD, author of Association of Nonmyeloablative Hematopoietic Stem Cell Transplantation With Neurological Disability in Patients With Relapsing-Remitting Multiple Sclerosis

Interview with Ezio Bonifacio, PhD, author of Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial

Interview with Levi J. Hargrove, PhD, author of Intuitive Control of a Powered Prosthetic Leg During Ambulation: A Randomized Clinical Trial

Interview with Carolina Malta Hansen, MD, author of Association of Bystander and First-Responder Intervention With Survival After Out-of-Hospital Cardiac Arrest in North Carolina, 2010-2013

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013

Edward H. Livingston, MD, interviews a war veteran and discusses PTSD with Maria Steenkamp, PhD, author of Psychotherapy for Military-Related PTSD, and Michele Spoont, PhD, author of Rational Clinical Exam: Does This Patient Have Posttraumatic Stress Disorder? The article by Dr Steenkamp reports that many military personnel and veterans with posttraumatic stress disorder achieve clinically meaningful improvement with use of the first-line trauma-focused interventions cognitive processing therapy and prolonged exposure.
 The Rational Clinical Examination Systematic Review by Dr Spoont examines the utility of self-report screening instruments for posttraumatic stress disorder among primary care and high-risk populations.

Polypharmacy is a rapidly worsening problem that hits elderly patients particularly hard.  As patients grow older, they need more medications but at the same time become less capable of managing the complexity of drug treatments.  In order to simplify treatment regimens for older patients, it is necessary to consider the evidence supporting treatment of various conditions and when the evidence is not particularly strong, reduce or eliminate medications accordingly.  Diabetes management in the elderly is highlighted in this podcast with specific attention given to deintensifying diabetes treatment in the elderly.

Articles discussed in this episode:

• Polypharmacy in the Aging Patient: Glycemic Control in Older Adults With Type 2 Diabetes: A Review (Kasia J. Lipska, MD, MHS)
• Evaluation and Treatment of Older Patients With Hypercholesterolemia: A Clinical Review (Timo E. Strandberg, MD, PhD)
• Trends in Prescription Drug Use Among Adults in the United States From 1999-2012 (Elizabeth D. Kantor, PhD, MPH)

Interview with Antoni Ribas, MD, PhD, author of Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma

Interview with Joel G. Ray, MD, MSc, FRCPC, author of Association Between MRI Exposure During Pregnancy and Fetal and Childhood Outcomes

Interview with Ann E. Kurth, PhD, RN, MSN, MPH, Task Force member and co-author of Primary Care Interventions to Support Breastfeeding: US Preventive Services Task Force Recommendation Statement

Interview with Roger L. Zemek, MD, author of Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Postconcussive Symptoms in Children and Adolescents

Interview with Freddie C. Hamdy, MD, FRCSEd(Urol), and Jenny L Donovan, PhD, FMedSci, authors of Patient-Reported Outcomes Following Treatment for Localized Prostate Cancer: Helping Decision Making for Patients and Their Physicians

Interview with Chien-Wen Tseng, MD, MPH, Task Force member and co-author of Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement

Interview with John W Epling, MD, MSEd, Task Force member and co-author of Preexposure Prophylaxis for the Prevention of HIV Infection: US Preventive Services Task Force Recommendation Statement

Interview with Paul A. Volberding, MD, and Hyman Scott, MD MPH, authors of HIV Screening and Preexposure Prophylaxis Guidelines: Following the Evidence

Interview with Jennifer L. Swails, MD, author of The Conundrum of the United States Medical Licensing Examination Score Reporting Structure

Interview with Gary H. Gibbons, M.D., author of Accelerating the Science of SCD Therapies—Is a Cure Possible?

Interview with Alexandra K. Glazier, JD, MPH, author of Success of Opt-In Organ Donation Policy in the United States

Interview with Daniel Brodie, MD, author of Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review

Interview with William H. Shrank, MD, MSHS, author of Waste in the US Health Care System: Estimated Costs and Potential for Savings

Interview with John P. A. Ioannidis, MD, DSc, author of Neglecting Major Health Problems and Broadcasting Minor, Uncertain Issues in Lifestyle Science

Interview with Pascale Carayon, PhD, author of Improving the System to Support Clinician Well-being and Provide Better Patient Care

Interview with Mark D. Huffman, MD, MPH, author of Implementation Strategies for Cardiovascular Polypills

Interview with Julia A. Segre, Ph.D., author of Manipulating the Human Microbiome to Manage Disease

Interview with Jack Resneck, MD, author of Refocusing Medication Prior Authorization on Its Intended Purpose

Interview with Jenny A. Doust, BMBS, author of Potential Consequences of Changing Disease Classifications

Physicians in Lombardy, Italy, have been overwhelmed by COVID-19 patients requiring critical care. Based on an existing ECMO center network they developed an ICU network to rapidly identify, triage, and manage patients infected with SARS-2-CoV. Maurizio Cecconi, MD, of Humanitas University in Milan discusses the region’s approach to the surge, including clinical and supply management, health care worker training and protection, and ventilation strategies, with JAMA Editor Howard Bauchner.

Read the article:

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response

The ARDS in COVID-19 patients appears more responsive to PEEP and prone ventilation, but seems to require prolonged ventilation and may be associated with myocardial injury. Michelle N. Gong, MD, MS, Chief of Critical Care Medicine at Montefiore Medical Center in the Bronx, discusses her department's experience managing critically ill coronavirus patients, procuring diagnostic tests and personal protective equipment (PPE) for her staff, and more.

JAMA Health Forum editors John Ayanian, MD, MPP, and Melinda Buntin, PhD, discuss changes in US health care and health policy driven by the coronavirus pandemic. Recorded April 16, 2020.

Interview with Aaron S. Kesselheim, MD, JD, MPH, author of Increasing Access to FDA Inspection Reports on Irregularities and Misconduct in Clinical Trials

Dyer, Andy, author

Pember, Mat, author

Dargavel, John

Krishnasamy, Karthika, author

Hill, Yvette Joan, author

Bittelli, Marco, author

Council of Nature Conservation Ministers (Australia). Working Group on Macropod Habitat

Sposito, Garrison, 1939- author

Wills, R. B. H. (Ronald Baden Howe), author

Sangmanee, Podjanee, author