Why is there something rather than nothing? We’re finally making enough antimatter to extract an answer – and it might reveal the dark side of the universe too

For the universe to exist as it does now, there must have been an imbalance between matter and antimatter early on, which may have been caused by neutrinos

Russia marked 75 years since the Soviet victory over Nazi Germany in World War Two on Saturday, but the coronavirus outbreak forced it to scale back celebrations. Olivia Chan reports.

Some bacteria sacrifice themselves when their colony is attacked by rivals, to save their relatives and make sure their shared genes are passed on

Bottlenose dolphins in Shark Bay, Australia, form alliances and coordinate the timing of their clicking noises to attract females and deter other males

Soil’s earthy smell comes from chemicals produced by bacteria called Streptomyces, which use the odour to attract springtails to help disperse their spores

Male ring-tailed lemurs rub their wrists to release a sweet, fruity smell that may be the first evidence of sex pheromones identified in primates

The United States Oil Fund LP, the largest oil-focused exchange-traded product (ETP) in the country, is moving to spread out its investments in oil futures in response to extreme market turbulence,...

Fossil traces hidden deep underground may solve the mystery of dark matter, the elusive substance that makes up 80 per cent of the universe

Seven Worlds, One Planet, David Attenborough’s stunning celebration of Earth’s biodiversity, prepares a new generation to save a beautiful world

Concerns about adversaries hacking democracy abound, but it’s sheer incompetence we should really be worried about, writes Annalee Newitz

This week, listen as David Attenborough reads nature classic The Peregrine, learn how skyscrapers and railway cuttings offer unlikely oases for wildlife, and watch an Altered Carbon anime spin-off

Kate Darling researches human-robot interaction. She explains why we are prone to forming emotional connections with robots and what we can learn from our relationships with pets and other animals

It's not every day that the face of a chief epidemiologist is inked as a tattoo. But then it's not every country that has tackled the coronavirus pandemic like Sweden.

Is toilet squatting really better than just sitting, or are the supposed benefits of a squatty potty just the fantasy of a rainbow-pooping unicorn?

Why is there something rather than nothing? We’re finally making enough antimatter to extract an answer – and it might reveal the dark side of the universe too

London's High Court on Friday threw out part of a claim brought by Meghan, Britain's Duchess of Sussex, against a tabloid newspaper for breaching her privacy, ruling that it had not acted dishonestly. Lauren Anthony reports.

Toy industry expert Jim Silver, CEO of TTPM talks about Mattel's new Barbies which will come in petite, tall and curvy and how they will impact falling barbie sales. Bobbi Rebell reports.

Health workers face a growing tide of hostility in Brazil for potentially spreading COVID-19.

Russia marked 75 years since the Soviet victory over Nazi Germany in World War Two on Saturday, but the coronavirus outbreak forced it to scale back celebrations. Olivia Chan reports.

With the spread of COVID-19, organizations worldwide have introduced remote working, which is having a direct impact on cybersecurity and the threat landscape.

Since the beginning of 2020, due to the COVID-2019 pandemic, life has shifted almost entirely to the Web. This is reflected in the goals of recent DDoS attacks, with the most targeted resources in Q1 being websites of medical organizations, delivery services, and gaming and educational platforms.

Title: Weight-Loss Surgery Works, No Matter How Long Patient Was Obese
Category: Health News
Created: 2/28/2020 12:00:00 AM
Last Editorial Review: 3/2/2020 12:00:00 AM

Title: LeAnn Rimes Brings Battle With Psoriasis to Center Stage
Category: Health News
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Title: Heart Attacks in the Morning Are More Severe
Category: Health News
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Title: Adjusting Your Attitude About Chronic Pain May Help You Sleep
Category: Health News
Created: 4/27/2012 4:06:00 PM
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Title: Blood Clot Risk for Outpatients Needs More Attention: Study
Category: Health News
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Category: Health News
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Title: Pediatricians Should Plan for Anthrax Attack, U.S. Experts Say
Category: Health News
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Title: High-Fiber Diet May Aid Heart Attack Survivors
Category: Health News
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Title: Health Tip: Batteries May Be Dangerous for Kids
Category: Health News
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Title: Where You're Treated for Heart Attack Matters
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Title: Could Certain Fatty Foods Be Linked to Aggressive Prostate Cancer?
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Title: Chicken Patties Sold at Costco Recalled
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Category: Health News
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Title: FDA Warns of Tattoo Dangers
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Title: Speed of Heart Attack Treatment Can Vary by State
Category: Health News
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Title: Sex Still Matters to Many Seniors, Survey Finds
Category: Health News
Created: 5/3/2018 12:00:00 AM
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Title: Overdose Attempts Skyrocket Among Teens, Young Adults: Study
Category: Health News
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Title: Cardiac Rehab Boosts Quality of Life After Heart Attack: Study
Category: Health News
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Title: During Coronavirus Pandemic, Don't Ignore Symptoms of Heart Attack, Stroke
Category: Health News
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Title: Heart Attacks, Strokes Are Declining Among People With Diabetes
Category: Health News
Created: 5/1/2020 12:00:00 AM
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Overexpression of transcription factor 3 in alveolar soft part sarcoma(ASPS) results in upregulation of cell proliferation pathways. No standard treatment algorithm exists for ASPS; multikinase inhibitors[tyrosine kinase inhibitor (TKI)] and immune checkpoint inhibitors (ICI) have shown clinical benefit. To date, no studies have reported on management strategies or sequencing of therapy. We evaluated ASPS treatment patterns and responses in an experimental therapeutics clinic. Genomic and morphoproteomic analysis was performed to further elucidate novel targets. We retrospectively reviewed patients with ASPS treated on clinical trials. Demographic and clinical next-generation sequencing (NGS) profiles were collected. AACR GENIE database was queried to further evaluate aberrations in ASPS. Morphoproteomic analysis was carried out to better define the biology of ASPS with integration of genomic and proteomic findings. Eleven patients with ASPS were identified; 7 received NGS testing and mutations in CDKN2A (n = 1) and hepatocyte growth factor (n = 1) were present. Ten patients were treated with TKIs with stable disease as best response and 4 patients with ICI (three partial responses). Within GENIE, 20 patients were identified harboring 3 called pathogenic mutations. Tumor mutation burden was low in all samples. Morphoproteomic analysis confirmed the expression of phosphorylated c-Met. In addition, fatty acid synthase and phosphorylated-STAT3 were detected in tumor cell cytoplasm and nuclei. Patients with ASPS have a quiescent genome and derive clinical benefit from VEGF-targeting TKIs. Morphoproteomic analysis has provided both additional correlative pathways and angiogenic mechanisms that are targetable for patients with ASPS. Our study suggests that sequential therapy with TKIs and immune checkpoint inhibitors is a reasonable management strategy.

Interprofessional education (IPE) is based on collaborative practices that increase the occasions for communication among those in various health professions. However, there is a paucity of literature about the effectiveness of IPE programs in health professions education. The aim of this systematic review and meta-analysis was to objectively assess the literature on the effectiveness of IPE in improving health professions students’ attitudes after training. The major scholarly databases were searched for relevant IPE studies involving predoctoral health professions students. Two independent researchers selected the studies, extracted the data, and assessed the quality of the studies. Meta-analyses of the outcomes were performed using random effects models. Sixteen articles were ultimately selected for detailed review and meta-analysis. The meta-analysis showed that IPE training had a significant influence on students’ understanding of collaboration and resulted in better attitudes about interprofessional teamwork. Subscale analysis showed that one subscale score (roles and responsibilities) did not statistically significantly improve after IPE training (p=0.06), whereas the other four subscale items showed statistically significant improvements (p<0.01). The test for overall effects showed that IPE training had a significantly positive influence on students’ attitudes about IPE (Z=6.85, p<0.01). Subgroup results showed that medical students had more positive attitudes about IPE than did dental students. Regardless of profession, women students responded with significantly more positive feedback than did men students (p=0.02). These results suggest that intervention through IPE training has had positive effects in health professions education. Gender was an important factor impacting the outcomes of IPE. However, further clinical practice interventions may be helpful to enhance the IPE competence of health professions students.

Purpose: Untreated and poorly controlled diabetes causes increased levels of blood glucose associated with poor periodontal disease outcomes. Dental hygienists can play a significant role in screening patients for diabetes mellitus, leading to referral and early diagnosis. The purpose of this study was to determine the knowledge, attitudes, practices, and barriers faced by clinical dental hygienists regarding diabetes risk assessment and screenings.Methods: A mixed method design was used with a convenience sample of dental hygienists in clinical practice (n=316). A 32 item, electronic survey was validated at item-level, and participants were recruited through multiple dental hygiene Facebook groups. Descriptive statistics were used to analyze the data. The survey also included two open-ended attitude questions that were interpreted using thematic analysis to pinpoint common patterns within the data.Results: Dental hygienists had high knowledge scores regarding diabetes and oral health, although many were unaware of their states' specific statutes and regulations for screening practices. Nearly all (95.9%), were likely to educate and refer patients (82%), although fewer than half (40.9%), were likely to perform chairside screening for diabetes. Emergent themes for barriers to screening were time, money, patient acceptance/willingness, lack of education, not having the proper tools, and states' rules and regulations.Conclusion: Despite high knowledge scores regarding diabetes and oral health, there is a gap in regards to dental hygienists' willingness to perform diabetes screenings in a clinical setting. Dental hygienists should be capable of integrating chairside diabetes screening practices into the process of care with proper training.

Adipocytes take up long chain FAs through diffusion and protein-mediated transport, whereas FA efflux is considered to occur by diffusion. To identify potential membrane proteins that are involved in regulating FA flux in adipocytes, the expression levels of 55 membrane transporters without known function were screened in subcutaneous adipose samples from obese patients before and after bariatric surgery using branched DNA methodology. Among the 33 solute carrier (SLC) transporter family members screened, the expression of 14 members showed significant changes before and after bariatric surgery. One of them, Slc43a3, increased about 2.5-fold after bariatric surgery. Further investigation demonstrated that Slc43a3 is highly expressed in murine adipose tissue and induced during adipocyte differentiation in primary preadipocytes and in OP9 cells. Knockdown of Slc43a3 with siRNA in differentiated OP9 adipocytes reduced both basal and forskolin-stimulated FA efflux, while also increasing FA uptake and lipid droplet accumulation. In contrast, overexpression of Slc43a3 decreased FA uptake in differentiated OP9 cells and resulted in decreased lipid droplet accumulation. Therefore, Slc43a3 seems to regulate FA flux in adipocytes, functioning as a positive regulator of FA efflux and as a negative regulator of FA uptake.