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US Military Is Furious At FCC Over 5G Plan That Could Interfere With GPS

An anonymous reader quotes a report from Ars Technica: GPS is facing a major interference threat from a 5G network approved by the Federal Communications Commission, U.S. military officials told Congress in a hearing on Wednesday. In testimony to the Senate Committee on Armed Services, Department of Defense Chief Information Officer Dana Deasy disputed the FCC's claims that conditions imposed on the Ligado network will protect GPS from interference. When the FCC approved Ligado's plan last month, the agency required a 23MHz guard band to provide a buffer between the Ligado cellular network and GPS. Deasy argued that this guard band won't prevent interference with GPS signals. Results from tests by federal agencies show that "conditions in this FCC order will not prevent impacts to millions of GPS receivers across the United States, with massive complaints expected to come," Deasy said. The FCC unanimously approved Ligado's application, but the decision is facing congressional scrutiny. "I do not think it is a good idea to place at risk the GPS signals that enable our national and economic security for the benefit of one company and its investors," Sen. James Inhofe (R-Okla.) said at the hearing, according to CNBC. "This is about much more than risking our military readiness and capabilities. Interfering with GPS will hurt the entire American economy." A spokesperson for FCC Chairman Ajit Pai called the military's concerns "baseless fear-mongering" in a statement quoted by Multichannel News. "The FCC made a unanimous, bipartisan decision based on sound engineering principles," the spokesperson said. The FCC said "the metric used by the Department of Defense to measure harmful interference does not, in fact, measure harmful interference," and that "testing on which they are relying took place at dramatically higher power levels than the FCC approved." "Ligado said Wednesday in a statement that it has gone to great lengths to prevent interference and will provide 'a 24/7 monitoring capability, a hotline, a stop buzzer or kill switch' and will 'repair or replace at Ligado's cost any government device shown to be susceptible to harmful interference,'" CNBC reported. The FCC also said it imposed a power limit of 9.8dBW on Ligado's downlink operations -- "a greater than 99 percent reduction from what Ligado proposed in its 2015 application," Pai said.

Read more of this story at Slashdot.




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NBA suspends season until further notice due to coronavirus

According to the news release, the NBA will use this hiatus to determine next steps for moving forward in regard to the coronavirus pandemic.

      




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4-star PF Caleb Furst commits to Purdue basketball

The Boilermakers received a commitment from Caleb Furst, a 2021 prospect from Fort Wayne Blackhawk Christian

      




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Furlough: New job starters 'left behind' despite scheme extension

Many people who started jobs in March cannot get furlough payments despite the scheme being extended.




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Coronavirus: Calls to shut down 'dirty fur trade'

Mink have caught Covid-19, adding to the list of infected animals, and prompting calls for trade bans.




fur

Police fury as 'hundreds' of people have pizzas, beers and wine in park

Britons have been accused of "ignoring" restrictions during the sunny bank holiday weekend, as the police and coastguard criticised those failing to observe guidelines.




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Furry Freak Brothers coming this fall, voiced by Woody Harrelson, John Goodman, Pete Davidson, and Tiffany Haddish

Yesterday saw the online premier of a mini-episode of a new animated comic series based on the classic Gilbert Shelton underground comic, the Fabulous Furry Freak Brothers. As a hippie wannabe teen in the 70s, this (and Zap! Comics) was everything to me.

In 1969, life in San Francisco consists of free love, communal living, and political protest. Freewheelin’ Franklin Freek (Harrelson), Fat Freddy Freekowtski (Goodman), Phineas T. Phreakers (Davidson) and their mischievous, foul-mouthed cat, Kitty (Haddish) spend their days dodging many things —- the draft, the narcs, and steady employment -– all while searching for an altered state of bliss.

But after partaking of a genetically-mutated strain of marijuana, the Freaks wake up 50 years later to discover a much different society. Quickly feeling like fish out of water in a high-tech world of fourth-wave feminism, extreme gentrification and intense political correctness, the Freaks learn how to navigate life in 2020 -— where, surprisingly, their precious cannabis is now legal.

OK, sounds good. But is it? If the reaction to the first mini-episode is any indication, maybe the Freaks should have remained in their drug-induced coma. As one Facbooker commented: "Get yourself a collected set of the original comic and skip this drivel!"

Read the rest




fur

Synergy in North Africa: Furthering Cooperation

21 January 2020

Discussions of North African integration have evoked ideas of a shared identity and a common destiny in the region. However, recent attempts to build regional blocs in North Africa have been unsuccessful. This paper examines the benefits of a ‘synergistic’ approach to North African cooperation. 

Dr Mohammed Masbah

Associate Fellow, Middle East and North Africa Programme

Mohamed El Dahshan

Associate Fellow, Middle East and North Africa Programme

2020-01-21-Market.jpg

A Tunisian vendor poses as he sells white truffles at a market in the town of Ben Guerdane, 40km west of the Libyan border, in February 2016. Photo: Getty Images.

Summary

  • North African integration is not a new idea. However, countries in the region have so far struggled to form a cohesive bloc with deep political, economic and social ties. Political instability has effectively deprioritized North African integration. A focus on thematic (political, economic and security) ‘synergies’ may provide a better framework for cooperation than seeking opportunities for all-encompassing ‘deep’ and ‘comprehensive’ integration.
  • Governments of North Africa dedicate considerable resources to domestic security. Much of their efforts are conducted at the national-level and directed towards threats from terrorists, insurgents and militias. Improved security cooperation would achieve better outcomes and economies of scale, including efforts to tackle human trafficking.
  • A new generation of jihadis has emerged in North Africa since 2011. Nearly 27 per cent of the 30,000 fighters who travelled to Syria are from the Maghreb. While government counterterrorism operations have been effective, countries have failed to address the root causes of radicalization.
  • Border economies have suffered as a consequence of a security focus on terrorism and smuggling, which has rendered many previously accepted cross-border trade activities illegal. States have struggled to provide alternative livelihoods for those who have lost this source of income. Border forces tend to lack the right combination of capacity, training and equipment to secure borders and often resort to heavy-handed tactics.
  • New thinking is required to develop a more human-centric and proactive approach to migration issues in the region, which continues to witness huge flows of migrants. The migration policy of Morocco, introduced through legislation in 2014, could be a model for North Africa.
  • The countries of North Africa have varying economic profiles, ranging from economically diverse Morocco to oil-and-gas-dependant Libya. However, they all face similar challenges including unemployment (particularly among the young), poor public-service delivery, low FDI levels, an oversized public sector, ineffective tax collection, and high informality.
  • Fostering entrepreneurship and the development of small and medium-sized enterprises (SMEs) are priorities for North African countries, particularly regarding job creation. Regulatory cooperation – such as harmonizing SME definitions, legislation and support institutions – across North Africa is an obvious area where further integration would encourage the development of start-ups and small businesses.
  • With the advent of the fourth industrial revolution, North African governments must address their technological gaps and work to improve public–private cooperation. In some sectors, such as the fintech industry, North African countries can build upon nascent synergies that have developed organically, such as those of start-up incubators and angel investors that work across the region.
  • Renewables, particularly solar energy production, are a promising development for North Africa. While regional initiatives, such as Desertec, have stalled due to political differences between countries, the sector has witnessed exponential growth in Tunisia, Egypt and Morocco, where the involvement of the private sector has proved successful.




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Brexit Would Be a Further Blow to the Special Relationship

20 April 2016

Xenia Wickett

Former Head, US and the Americas Programme; Former Dean, The Queen Elizabeth II Academy for Leadership in International Affairs
But increased British leadership, in Europe and beyond, could reverse the decline of US–UK ties.

2016-04-20-Cameron-Obama.jpg

Barack Obama and David Cameron at the 2016 Nuclear Security Summit on 1 April 2016 in Washington. Photo by Getty Images.

The US−UK ‘Special Relationship’ is in decline, and a British decision to leave the EU would hasten its demise. As Great Britain increasingly becomes just one of America’s many strategic relationships, Brexit would speed the transfer of US attention and energy from the UK to the continent. This, however, does not need to be inevitable. The necessary ingredient to reverse this decline is stronger British leadership internationally.

The US government has made it abundantly clear that its preference is to see the UK remain in the European Union. In January 2013, when David Cameron had not yet committed to a referendum, Phil Gordon, the US assistant secretary of state for European affairs bluntly stated that it is in the American interest for the US ‘to see a strong British voice in that European Union.’ The fact that a senior US official would go so far – to be seen to intervene so early in a divisive domestic political issue – spoke volumes about how important this is to America. This week, President Obama will visit the UK to send an equally firm, if polite, message to the British public.

Why does the US want the UK to remain in Europe?

From the US perspective, there are three principal elements that the UK brings to the table in the bilateral relationship. The first stems from Britain’s capabilities, particularly in the military and intelligence arenas. US−UK intelligence sharing, the closest for both countries, has a long history dating back to the Second World War. For good or ill the UK has been among America’s leading allies in every major conflict the US has been involved in for the last quarter of a century – in the Gulf War, Bosnia and Kosovo, Afghanistan, the war in Iraq, the interventions in Libya as well as current operations against ISIS in Iraq and, belatedly, Syria.

The second relates to the political value of having a reliable partner in international engagements – and thereby avoiding the perception of acting unilaterally. Shared history and values, and thus often perspectives (as well as capabilities) have ensured that the UK has long been the first port of call for the US when seeking to solve international problems or build coalitions. At the same time, Britain’s historical global reach and diplomatic experience around the world (not least in areas of current concern such as Afghanistan, Pakistan, Israel and Palestine, and Iraq) have provided American policy-makers with valuable input on foreign policy issues that has contributed to their own internal decision making.

The third area of added value for the US is Britain’s place in the EU. While British and US policy preferences may at times diverge, as they have recently on the Israel−Palestine issue, for example, their common outlooks and interests mean that Britain is the closest thing that the United States has to having a voice in the EU. At the same time, the US also sees the UK as the country most likely to support an open trade and investment agenda and a more proactive approach to dealing with the challenges in Europe’s neighbourhood, policies that leaders in both countries agree are necessary to make the EU a more effective actor and better partner to the US on the international scene.

The transition from US−UK ties to US−European ties

In recent years, however, the US has begun to diversify its relationships within Europe, in part as the UK has become unable or unwilling to step up and fulfil these three elements of paramount importance to the US.

Defence and intelligence

With regards to defence capabilities, it is no longer the UK that the United States inevitably looks to first. In Libya, the operation that started with the defence of Benghazi from Gaddafi’s forces in March 2012 (that eventually came to remove Gaddafi himself) was jointly led by the French and the British, although then-French president Nicolas Sarkozy appeared to be the driving force. More recently, it was the French with whom the US partnered in responding to the terrorist activities in Mali and who were first to support the US in action in Syria (following a UK parliamentary vote to stay out in August 2013 and a belated vote to act in December 2015). But in recent years others have worked more closely with the United States militarily as well, including in particular Poland and Denmark (although with the new government in Poland, the relationship might wither again).

This trend towards more diversified military engagement with other European states looks set to continue in the near term. Despite taking a tough position in the 2014 NATO Summit to reinforce the NATO commitment of two per cent of GDP spending on defence, the Cameron government came very close to falling below this line in 2015 (after five years of real defence cuts). The eventual decision to commit to meet this target, along with the newly released Strategic Defence and Security Review (SDSR), have somewhat reassured American policy-makers of the UK’s continued ambition and capabilities. But there remains a lack of US confidence that this is only a temporary uptick in UK attention on defence. Meanwhile, America will continue to expand its horizons.

The story on intelligence sharing is slightly different, but here too obstacles have arisen in the close US-UK exchange of information. Since the end of the Second World War, the US and UK have been part of the ‘Five Eyes’ alliance – with Australia, New Zealand and Canada – that allows the close sharing of intelligence. And arguably, within the Five Eyes, the links between the US and UK are the closest of all. However, more recently, tensions have emerged. Over the past five or so years, the British judicial system in particular has pushed back on US confidentiality rules in ways that make the US intelligence services nervous of continuing to share information; given the current close relationship, this could be more of an obstacle than it is for other countries sharing intel with the US.

At the same time, with the ISIS-inspired resurgence in the terrorist threat in both Europe and the US, it is becoming increasingly clear that the close intelligence sharing between the US and UK must take place much more widely. The current systems – through NATO or INTERPOL – have proven too slow and ineffective, as the recent attacks in Paris and Brussels have made clear. Sharing among the US and UK, or even among the Five Eyes, is insufficient – increasingly the relationships will have to be broadened.

Partnership

The US is also looking elsewhere for partnership in its international engagements, including on some of the issues that are at the top of the inbox for the American president.

On responding to Russian actions in Ukraine, it is clear that German Chancellor Angela Merkel is in the lead, both in corralling Europeans to maintain the sanctions but also in negotiating with Russian President Vladimir Putin. This was highlighted in the creation of the Normandy format in the summer of 2014, a group encompassing Germany, France, Russia and Ukraine (but not the UK or the US), to resolve the situation in the east of Ukraine. On another issue of significant import to the United States, European economic prosperity and stability, Merkel is again the leading actor in Europe.

In the case of targeted bombing in Syria, it was not the British that were first to join the United States in the offensive against ISIS, but instead the French. President Francois Hollande also proved far more proactive after Syrian President Assad crossed the chemical weapons ‘redline’ in 2013, although in the end France was left hanging when President Obama decided to step back from military action after the failure of the British parliamentary vote to authorize UK involvement.

Finally, on at least one issue of great import to the US – China – the UK appears to be diverging meaningfully. The most recent case – the UK decision to join the Asian Infrastructure Investment Bank in March 2015 – is perhaps the starkest example of such differing policy positions that have caused significant frustration in the US.

Influence in the European Union

With regards to Europe, even before the referendum was formally announced, it was increasingly clear that the UK was less inclined to engage proactively in the EU. A number of factors have ensured that, particularly since 2010, the UK has become less influential there.

British influence has been diminished through actions by the Cameron government that have, perhaps unnecessarily, antagonized many across the Channel. Many European conservatives became frustrated early in Cameron’s tenure when he decided to take the Conservative Party out of the principal conservative group in the European parliament, the European People’s Party. This sentiment only worsened in recent years as, albeit for perhaps understandable domestic political reasons, Cameron conducted an adversarial negotiation with his European partners in an effort to secure reforms to the EU and changes in Britain’s terms of membership.

The UK also no longer sends its best and brightest to EU institutions. Many of the leading British officials who once occupied high offices there have left and been replaced by other continental Europeans. This deprives Britain of an important source of influence within the EU.

It is clear that if the US wants influence in the EU, it needs more partners there than just the UK. Britain is still important, and would be a strong driver to make the institution more efficient, but as its influence declines it is no longer sufficient. A Leave vote would immediately dispose of that influence entirely.

The UK is ‘one among many’ for the US

What is clear is that increasingly the UK is not ‘first among equals’ in Europe but ‘one among many’ for the United States. America is diversifying its relationships. More and more the US can find other allies and friends to fulfil the needs in which the UK no longer has interest.

If the UK leaves the European Union, the pace of this trend will only quicken. In addition to needing to find alternative partners to address these policy gaps, the UK will likely no longer have the time to devote to the United States that it does today. If Brexit takes place, Whitehall will find itself inundated with issues which had previously been managed by the EU, from trade deals with third parties to negotiating constant market access adjustments with the EU. Thus, very quickly, British resources are likely to be pulled from the US portfolio, and issues of common concern will get drowned out by other agendas. At least for a while, the US will likely get short shrift.

America’s response then can only be to hasten its search for other partners both in Europe and beyond. And there lies an inevitable negative spiral for the Special Relationship.

Can anything be done to save the Special Relationship?

There is no question that the US and UK will continue to have a strong and positive relationship, but it is clear that, without action, either in or out of Europe, its ‘specialness’ will decline. As the arguments above lay out, the only question is how fast this demise takes place. But there is something that could not only halt, but also reverse this trend.

As President Obama made starkly clear in his interviews with Jeffrey Goldberg in the Atlantic, what he wants most from partners and allies is for them to step up – to show more leadership (a sentiment that the Republican candidates for president would push even further). With the perceived failure of interventions over the last 15 years – from Afghanistan to Iraq to Libya –many politicians and publics have become wary of foreign military intervention. This is true in Europe and the US; but Americans have often felt that they have been left holding both the bag and the blame.  

It should be noted that more leadership does not necessarily mean more military engagement. Or even, necessarily, more spending on foreign policy tools (whether diplomatic, military or development). But it does mean a willingness to step up and take responsibility for trying to guide international events and for promoting common interests.

In the UK’s SDSR released towards the end of 2015, the government stated its intention to remain fully engaged globally; however, its actions belie this. Where Asia is concerned – an issue that is front and centre for the US – the UK joins other European powers in arguing that its lack of resources in the region makes it unable to contribute meaningfully to maintaining stability. Even closer to home, in the Middle East, the UK has been wary of leading.

It is understandable why the UK is hesitant to take such a leadership role, even as part of a coalition, in some of the larger strategic challenges the world faces. There are few benefits. Merely finding the human capital to coordinate an international response is difficult. The complexity of these problems ensures they rarely work out as hoped, and more often lead to international contempt rather than approbation. Thus it is no great surprise that the UK, along with much of the rest of the world, resists the temptation to be out in front. But there are opportunities – two issues that the US would likely welcome greater British leadership on would be building support in Europe for the Transatlantic Trade and Investment Partnership and taking a more active role in maintaining stability in Asia. Further, having a stronger European partner on issues in the Middle East (from Yemen to Syria) – Europe’s near abroad – is something that many American policy-makers have suggested. 

But the UK would not have to stand alone. With a little leadership from the UK, the US would provide support, as would many others currently loath to take the lead but with very strong interests in the outcomes. But someone has to start; as Obama made clear, there needs to be less ‘free riding’.

If the UK wants to reverse the decline of the Special Relationship, it will need to show more leadership internationally. This should not be as hard as it might seem. Not only does it conform to the government’s own strategy (as laid out in the SDSR) but public concern over further interventions is weaker than one might imagine. Such a leadership role would once again show to the United States the value of the Special Relationship.

This article has also been published by Real Clear World.

To comment on this article, please contact Chatham House Feedback




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Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations [Enzymology]

3-Mercaptopyruvate sulfur transferase (MPST) catalyzes the desulfuration of 3-mercaptopyruvate (3-MP) and transfers sulfane sulfur from an enzyme-bound persulfide intermediate to thiophilic acceptors such as thioredoxin and cysteine. Hydrogen sulfide (H2S), a signaling molecule implicated in many physiological processes, can be released from the persulfide product of the MPST reaction. Two splice variants of MPST, differing by 20 amino acids at the N terminus, give rise to the cytosolic MPST1 and mitochondrial MPST2 isoforms. Here, we characterized the poorly-studied MPST1 variant and demonstrated that substitutions in its Ser–His–Asp triad, proposed to serve a general acid–base role, minimally affect catalytic activity. We estimated the 3-MP concentration in murine liver, kidney, and brain tissues, finding that it ranges from 0.4 μmol·kg−1 in brain to 1.4 μmol·kg−1 in kidney. We also show that N-acetylcysteine, a widely-used antioxidant, is a poor substrate for MPST and is unlikely to function as a thiophilic acceptor. Thioredoxin exhibits substrate inhibition, increasing the KM for 3-MP ∼15-fold compared with other sulfur acceptors. Kinetic simulations at physiologically-relevant substrate concentrations predicted that the proportion of sulfur transfer to thioredoxin increases ∼3.5-fold as its concentration decreases from 10 to 1 μm, whereas the total MPST reaction rate increases ∼7-fold. The simulations also predicted that cysteine is a quantitatively-significant sulfane sulfur acceptor, revealing MPST's potential to generate low-molecular-weight persulfides. We conclude that the MPST1 and MPST2 isoforms are kinetically indistinguishable and that thioredoxin modulates the MPST-catalyzed reaction in a physiologically-relevant concentration range.




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Episode 39: American Hustle/The Hobbit 2/Anchorman 2/Out of the Furnace

  • American Hustle
  • The Hobbit: The Desolation of Smaug
  • Anchorman 2: The Legend Continues
  • Out of the Furnace
  • 2014 Bucket List Films
  • What We Watched: Bully, Prisoners, Powwow Highway, Miss Representation, The Spectacular Now, Knuckle, Shut Up And Play The Hits, Mike Birbiglia: My Girlfriend's Boyfriend and The Act of Killing. 


Next Episode: Martin Scorcese's The Wolf of Wall Street and Spike Jonze's Her. 




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CBD Press Release: One Step Further towards the Adoption of the Aichi Nagoya Protocol on Access and Benefit Sharing.




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CBD Communiqué: UN General Assembly Event to Spur Action to Stem Further Biodiversity Loss.




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CBD News: Governments have agreed to a series of actions that will further bolster the Nagoya Protocol on Access and Benefit Sharing, facilitate its effective implementation, and ensure that countries have the necessary resources to take the next steps to




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CBD News: Governments at an international biodiversity science meeting have agreed on a set of actions for the further implementation of the Convention on Biological Diversity (CBD) and its Strategic Plan for Biodiversity 2011-2020.




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CBD News: It is a great pleasure to participate in this session of the Commission on Genetic Resources for Food and Agriculture and to discuss opportunities to further integrate biodiversity within the agriculture and food production sectors.




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CBD News: Over the next two weeks, the Convention on Biological Diversity's (CBD) bodies on science and implementation will meet to provide further guidance on accelerated efforts to achieve the Aichi Biodiversity Targets by the end of the year 2020,




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CBD Notification SCBD/IMS/JMF/NVW/86292 (2019-117): Follow-up invitation to participate in and/or contribute to the piloting and further development of a methodology for the voluntary peer review of national biodiversity strategies and action plans





fur

Furloughed workers offered free JavaScript courses

Companies with large numbers of furloughed workers are offering staff an introductory course in JavaScript coding, thanks to the European coding bootcamp, Codeworks.




fur

OU Reproductive Medicine physician receives grant to further study frozen embryo transfers

(University of Oklahoma) OU Medicine recently received a $1.4 million grant from the National Institutes of Health to study one method of embryo transfer involved in IVF: cryopreserved (frozen) embryo transfer.




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Synergy in North Africa: Furthering Cooperation

21 January 2020

Discussions of North African integration have evoked ideas of a shared identity and a common destiny in the region. However, recent attempts to build regional blocs in North Africa have been unsuccessful. This paper examines the benefits of a ‘synergistic’ approach to North African cooperation. 

Dr Mohammed Masbah

Associate Fellow, Middle East and North Africa Programme

Mohamed El Dahshan

Associate Fellow, Middle East and North Africa Programme

2020-01-21-Market.jpg

A Tunisian vendor poses as he sells white truffles at a market in the town of Ben Guerdane, 40km west of the Libyan border, in February 2016. Photo: Getty Images.

Summary

  • North African integration is not a new idea. However, countries in the region have so far struggled to form a cohesive bloc with deep political, economic and social ties. Political instability has effectively deprioritized North African integration. A focus on thematic (political, economic and security) ‘synergies’ may provide a better framework for cooperation than seeking opportunities for all-encompassing ‘deep’ and ‘comprehensive’ integration.
  • Governments of North Africa dedicate considerable resources to domestic security. Much of their efforts are conducted at the national-level and directed towards threats from terrorists, insurgents and militias. Improved security cooperation would achieve better outcomes and economies of scale, including efforts to tackle human trafficking.
  • A new generation of jihadis has emerged in North Africa since 2011. Nearly 27 per cent of the 30,000 fighters who travelled to Syria are from the Maghreb. While government counterterrorism operations have been effective, countries have failed to address the root causes of radicalization.
  • Border economies have suffered as a consequence of a security focus on terrorism and smuggling, which has rendered many previously accepted cross-border trade activities illegal. States have struggled to provide alternative livelihoods for those who have lost this source of income. Border forces tend to lack the right combination of capacity, training and equipment to secure borders and often resort to heavy-handed tactics.
  • New thinking is required to develop a more human-centric and proactive approach to migration issues in the region, which continues to witness huge flows of migrants. The migration policy of Morocco, introduced through legislation in 2014, could be a model for North Africa.
  • The countries of North Africa have varying economic profiles, ranging from economically diverse Morocco to oil-and-gas-dependant Libya. However, they all face similar challenges including unemployment (particularly among the young), poor public-service delivery, low FDI levels, an oversized public sector, ineffective tax collection, and high informality.
  • Fostering entrepreneurship and the development of small and medium-sized enterprises (SMEs) are priorities for North African countries, particularly regarding job creation. Regulatory cooperation – such as harmonizing SME definitions, legislation and support institutions – across North Africa is an obvious area where further integration would encourage the development of start-ups and small businesses.
  • With the advent of the fourth industrial revolution, North African governments must address their technological gaps and work to improve public–private cooperation. In some sectors, such as the fintech industry, North African countries can build upon nascent synergies that have developed organically, such as those of start-up incubators and angel investors that work across the region.
  • Renewables, particularly solar energy production, are a promising development for North Africa. While regional initiatives, such as Desertec, have stalled due to political differences between countries, the sector has witnessed exponential growth in Tunisia, Egypt and Morocco, where the involvement of the private sector has proved successful.




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Development of a sensitive and quantitative method for the identification of two major furan fatty acids in human plasma

Long Xu
Apr 1, 2020; 61:560-569
Methods




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Development of a sensitive and quantitative method for the identification of two major furan fatty acids in human plasma [Methods]

This article focuses on the establishment of an accurate and sensitive quantitation method for the analysis of furan fatty acids. In particular, the sensitivity of GC/MS and UPLC/ESI/MS/MS was compared for the identification and quantification of furan fatty acids. Different methylation methods were tested with respect to GC/MS analysis. Special attention needs to be paid to the methylation of furan fatty acids, as acidic catalysts might lead to the degradation of the furan ring. GC/MS analysis in full-scan mode demonstrated that the limit of quantitation was 10 μM. UPLC/ESI/MS/MS in multiple reaction monitoring mode displayed a higher detection sensitivity than GC/MS. Moreover, the identification of furan fatty acids with charge-reversal derivatization was tested in the positive mode with two widely used pyridinium salts. Significant oxidation was unexpectedly observed using N-(4-aminomethylphenyl) pyridinium as a derivatization agent. The formed 3-acyl-oxymethyl-1-methylpyridinium iodide derivatized by 2-bromo-1-methylpyridinium iodide and 3-carbinol-1-methylpyridinium iodide improved the sensitivity more than 2,000-fold compared with nonderivatization in the negative mode by UPLC/ESI/MS/MS. This charge-reversal derivatization enabled the targeted quantitation of furan fatty acids in human plasma. Thus, it is anticipated that this protocol could greatly contribute to the clarification of pathological mechanisms related to furan fatty acids and their metabolites.




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Hillel Furstenberg & Grigoriĭ Margulis win Abel Prize

Hillel Furstenberg and Grigoriĭ Margulis have been announced as the winners of the 2020 Abel Prize.  You can read the official announcement here.   There is a news item about the prize on the AMS website.  Needless to say, they have … Continue reading



  • Prizes and awards

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Digital Jamaica throws sales lifeline to furniture companies

DESPITE TUMBLING sales and challenges with hire-purchase accounts, two of the largest retailers of home furniture and appliances, Courts Jamaica and Singer Jamaica, have found glimmers of hope during the COVID-19 pandemic. That’s because work-from...




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Foundations of Utility and Risk (FUR) Conference, Sydney, July 1-4, 2020

ABSTRACT SUBMISSION DEADLINE JANUARY 15, 2020 The Foundations of Utility and Risk (FUR) Conference will, for the first time, take place in the Asia Pacific area in 2020. We invite all Economists and other Social Scientists interested in the study of Decision-making to submit papers to the conference. Since 1982, FUR gathers every two years […]

The post Foundations of Utility and Risk (FUR) Conference, Sydney, July 1-4, 2020 appeared first on Decision Science News.




fur

Oregon schools to furlough teachers, boost pay with stimulus




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Oregon schools to furlough teachers, boost pay with stimulus




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Oregon schools to furlough teachers, boost pay with stimulus




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The diagnosis, prevention, & treatment of diseases of the heart, and of aneurism : with observations on rheumatism / by J.J. Furnivall.

London : J. Churchill, 1845.




fur

Diagnostisches Lexikon fur praktische Arzte / unter Mitwirkung der Herren A. Adamkiewicz [and others] ; herausgegeben von Anton Bum und M.T. Schnirer.

Wien : Urban & Schwarzenberg, 1893-1895.




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Die acute Entzundung des hautigen Labyrinthes des Ohres (Otitis labyrinthica s. intima) irrthumlich fur Meningitis cerebro-spinalis epidemica gehalten : fur praktische Aerzte dargestellt / von R. Voltolini.

Breslau : E. Morgenstern, 1882.




fur

Die Aetiologie der alteren und modernen Ophthalmologie in ihrer besonderen Bedeutung fur die Therapie / von Wilhelm Manz.

Freiburg : H.M. Poppen, 1886.




fur

Die Elektrotherapie und deren besondere Verwerthung in Nerven- und Muskelkrankheiten : ein Handbuch fur praktische Arzte / von Moriz Rosenthal.

Wien : Wilhelm Braumuller, 1873.




fur

Die fur das Deutsche Reich geltenden Bestimmungen uber die Prusungen der Aerzte und Bahnarzte.

Leipzig : Roszberg, 1884.




fur

Die Furchen und Wulste am Grosshirn des Menschen : zugleich als Erlauterung zu dem Hirnmodell / von Ad. Pansch.

Berlin : R. Oppenheim, 1879.




fur

Die Gehirnerweichung der Irren (Dementia paralytica) fur Aerzte und Studirende / bearbeitet von Theodor Simon.

Hamburg : Wilhelm Mauke, 1871.




fur

Die Giftthiere und ihre wirkung auf den Menschen : ein Handbuch fur Mediciner / von Otto v. Linstow.

Berlin : A. Hirschwald, 1894.




fur

Die Heilung des chronischen Morphinismus (Cocainismus etc.) ohne Zwang und Qual : fur Laien und Aerzte / von Otto Emmerich.

Berlin : H. Steinitz, 1894.




fur

Die Infections-Krankheiten, ihre Entstehung, ihr Wesen und ihre Bekampfung : fur Aerzte und Verwaltungs-Beamte / von W. Plange.

Berlin : S. Karger, 1894.




fur

Die Kostordnung der psychiatrischen und Nervenklinik der Universitat Halle-Wittenberg : fur Aerzte und Verwaltungsbeamte / herausgegeben und erlautert von E. und Ed. Hitzwig.

Jena : G. Fischer, 1897.




fur

Die Krankenpflege im Frieden und im Kriege : zum Gebrauch fur Jedermann insbesondere fur Pflegerinnen, Pfleger und Arzte / von Paul Rupprecht.

Leipzig : F.C.W. Vogel, 1890.




fur

Die Krankheiten der Verdauungsorgane im Kindesalter fur Arzte und Studierende / von Ernst Schreiber.

Wurzburg : A. Stuber, 1902.




fur

Die Physiologie und Pathologie des Wochenbetts : fur studirende und arzte / von Hermann Fehling.

Stuttgart : F. Enke, 1897.




fur

Die physiologische Diagnostik als Basis fur rationelle Therapie / systematisch bearbeitet von Josef Neisser.

Berlin : A. Hirschwald, 1879.




fur

Die Sicherung von Leben und Gesundheit im Fabrik- und Gewerbe-Betriebe, auf der Brusseler Ausstellung vom Sommer 1876. Bericht, im Auftrage des Ministers fur Handel, Gewerbe, etc. erstattet / von F. Reichel.

Berlin : F. Kortkampf, 1877.




fur

Die Ursachen des Stotterubels und dessen naturgemasse Heilung : fur Aerzte, Erzieher & Sprachleidende / von A.E. Gerdts.

Bingen am Rhein : Selbstverlag des Verfassers, 1885.




fur

Dritter Bericht der Poliklinik fur Kinder zu Leipzig : umfassend die Jahre 1857-1860 / von C. Hennig.

Leipzig : W. Engelmann, 1860.




fur

Virus: Idaho school district furloughs 145 employees