are Unrelated Folks Who Look Alike Share Similar DNA By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Unrelated Folks Who Look Alike Share Similar DNACategory: Health NewsCreated: 8/23/2022 12:00:00 AMLast Editorial Review: 8/24/2022 12:00:00 AM Full Article
are Gout Flare-Ups Could Raise Heart Risk for Weeks After By www.medicinenet.com Published On :: Thu, 4 Aug 2022 00:00:00 PDT Title: Gout Flare-Ups Could Raise Heart Risk for Weeks AfterCategory: Health NewsCreated: 8/3/2022 12:00:00 AMLast Editorial Review: 8/4/2022 12:00:00 AM Full Article
are What Are Symptoms of a Silent Migraine? By www.medicinenet.com Published On :: Fri, 17 Jun 2022 00:00:00 PDT Title: What Are Symptoms of a Silent Migraine?Category: Diseases and ConditionsCreated: 6/17/2022 12:00:00 AMLast Editorial Review: 6/17/2022 12:00:00 AM Full Article
are What Are the 4 Stages of Congestive Heart Failure? By www.medicinenet.com Published On :: Fri, 26 Aug 2022 00:00:00 PDT Title: What Are the 4 Stages of Congestive Heart Failure?Category: Diseases and ConditionsCreated: 6/24/2020 12:00:00 AMLast Editorial Review: 8/26/2022 12:00:00 AM Full Article
are Here Are the Top 15 Anti-Inflammatory Foods for Your Diet To Reduce Inflammation By www.medicinenet.com Published On :: Fri, 26 Aug 2022 00:00:00 PDT Title: Here Are the Top 15 Anti-Inflammatory Foods for Your Diet To Reduce InflammationCategory: Health and LivingCreated: 8/26/2022 12:00:00 AMLast Editorial Review: 8/26/2022 12:00:00 AM Full Article
are 7 Scrumptious Drinks That Are High in Iron By www.medicinenet.com Published On :: Fri, 26 Aug 2022 00:00:00 PDT Title: 7 Scrumptious Drinks That Are High in IronCategory: Health and LivingCreated: 8/26/2022 12:00:00 AMLast Editorial Review: 8/26/2022 12:00:00 AM Full Article
are What Are the Benefits of Drinking Tea With Milk? By www.medicinenet.com Published On :: Fri, 26 Aug 2022 00:00:00 PDT Title: What Are the Benefits of Drinking Tea With Milk?Category: Health and LivingCreated: 8/26/2022 12:00:00 AMLast Editorial Review: 8/26/2022 12:00:00 AM Full Article
are 8 Reasons You Are Not Losing Weight on Keto By www.medicinenet.com Published On :: Fri, 26 Aug 2022 00:00:00 PDT Title: 8 Reasons You Are Not Losing Weight on KetoCategory: Health and LivingCreated: 8/26/2022 12:00:00 AMLast Editorial Review: 8/26/2022 12:00:00 AM Full Article
are Are Green Mussels Good for You? By www.medicinenet.com Published On :: Fri, 26 Aug 2022 00:00:00 PDT Title: Are Green Mussels Good for You?Category: Health and LivingCreated: 8/26/2022 12:00:00 AMLast Editorial Review: 8/26/2022 12:00:00 AM Full Article
are Are Cholesterol Tests Always Accurate? By www.medicinenet.com Published On :: Wed, 9 Mar 2022 00:00:00 PDT Title: Are Cholesterol Tests Always Accurate?Category: Diseases and ConditionsCreated: 3/9/2022 12:00:00 AMLast Editorial Review: 3/9/2022 12:00:00 AM Full Article
are Which Nuts Are Best to Lower Cholesterol? By www.medicinenet.com Published On :: Tue, 10 May 2022 00:00:00 PDT Title: Which Nuts Are Best to Lower Cholesterol?Category: Diseases and ConditionsCreated: 5/10/2022 12:00:00 AMLast Editorial Review: 5/10/2022 12:00:00 AM Full Article
are Are Plant Sterols Good for Lowering Cholesterol? By www.medicinenet.com Published On :: Thu, 12 May 2022 00:00:00 PDT Title: Are Plant Sterols Good for Lowering Cholesterol?Category: Diseases and ConditionsCreated: 5/12/2022 12:00:00 AMLast Editorial Review: 5/12/2022 12:00:00 AM Full Article
are More Athletes Are Getting Their Nutrition Through an IV. This Should Stop, Experts Say By www.medicinenet.com Published On :: Thu, 18 Aug 2022 00:00:00 PDT Title: More Athletes Are Getting Their Nutrition Through an IV. This Should Stop, Experts SayCategory: Health NewsCreated: 8/17/2022 12:00:00 AMLast Editorial Review: 8/18/2022 12:00:00 AM Full Article
are Summer Bug Bite? Expert Gives Answers on Care By www.medicinenet.com Published On :: Mon, 1 Aug 2022 00:00:00 PDT Title: Summer Bug Bite? Expert Gives Answers on CareCategory: Health NewsCreated: 7/30/2022 12:00:00 AMLast Editorial Review: 8/1/2022 12:00:00 AM Full Article
are Dietary Supplements: Are You Throwing Money Away? By www.medicinenet.com Published On :: Tue, 2 Aug 2022 00:00:00 PDT Title: Dietary Supplements: Are You Throwing Money Away?Category: Health NewsCreated: 8/2/2022 12:00:00 AMLast Editorial Review: 8/2/2022 12:00:00 AM Full Article
are Will Inflation Cut Back on Your Health Care? By www.medicinenet.com Published On :: Mon, 8 Aug 2022 00:00:00 PDT Title: Will Inflation Cut Back on Your Health Care?Category: Health NewsCreated: 8/8/2022 12:00:00 AMLast Editorial Review: 8/8/2022 12:00:00 AM Full Article
are Here's How the Inflation Reduction Act Will Lower the Cost of Health Care By www.medicinenet.com Published On :: Wed, 17 Aug 2022 00:00:00 PDT Title: Here's How the Inflation Reduction Act Will Lower the Cost of Health CareCategory: Health NewsCreated: 8/17/2022 12:00:00 AMLast Editorial Review: 8/17/2022 12:00:00 AM Full Article
are Are Skin Rashes Contagious? By www.medicinenet.com Published On :: Fri, 5 Aug 2022 00:00:00 PDT Title: Are Skin Rashes Contagious?Category: Diseases and ConditionsCreated: 8/10/2015 12:00:00 AMLast Editorial Review: 8/5/2022 12:00:00 AM Full Article
are Up Your Skin Care Routine During Hot Summer Months By www.medicinenet.com Published On :: Mon, 15 Aug 2022 00:00:00 PDT Title: Up Your Skin Care Routine During Hot Summer MonthsCategory: Health NewsCreated: 8/13/2022 12:00:00 AMLast Editorial Review: 8/15/2022 12:00:00 AM Full Article
are What Are the Main Parts of the Male Reproductive System? By www.medicinenet.com Published On :: Thu, 7 Jul 2022 00:00:00 PDT Title: What Are the Main Parts of the Male Reproductive System?Category: Diseases and ConditionsCreated: 7/7/2022 12:00:00 AMLast Editorial Review: 7/7/2022 12:00:00 AM Full Article
are What Are the 5 Warning Signs of Bladder Cancer? By www.medicinenet.com Published On :: Wed, 8 Jun 2022 00:00:00 PDT Title: What Are the 5 Warning Signs of Bladder Cancer?Category: Diseases and ConditionsCreated: 4/22/2021 12:00:00 AMLast Editorial Review: 6/8/2022 12:00:00 AM Full Article
are What Therapeutic Options Are Available for Treating an Antiretroviral Naive Patient? By www.medicinenet.com Published On :: Thu, 16 Jun 2022 00:00:00 PDT Title: What Therapeutic Options Are Available for Treating an Antiretroviral Naive Patient?Category: Diseases and ConditionsCreated: 6/16/2022 12:00:00 AMLast Editorial Review: 6/16/2022 12:00:00 AM Full Article
are Are High-Tech Blood Pressure Monitors Really Worth It? By www.medicinenet.com Published On :: Tue, 16 Aug 2022 00:00:00 PDT Title: Are High-Tech Blood Pressure Monitors Really Worth It?Category: Health NewsCreated: 8/16/2022 12:00:00 AMLast Editorial Review: 8/16/2022 12:00:00 AM Full Article
are Self-Employed Women Are Often Healthier: Study By www.medicinenet.com Published On :: Mon, 8 Aug 2022 00:00:00 PDT Title: Self-Employed Women Are Often Healthier: StudyCategory: Health NewsCreated: 8/8/2022 12:00:00 AMLast Editorial Review: 8/8/2022 12:00:00 AM Full Article
are Who Fares Worse After Multiple Sclerosis Strikes? By www.medicinenet.com Published On :: Fri, 12 Aug 2022 00:00:00 PDT Title: Who Fares Worse After Multiple Sclerosis Strikes?Category: Health NewsCreated: 8/11/2022 12:00:00 AMLast Editorial Review: 8/12/2022 12:00:00 AM Full Article
are U.S. Hospitals Are Getting Safer for Patients, Study Finds By www.medicinenet.com Published On :: Wed, 20 Jul 2022 00:00:00 PDT Title: U.S. Hospitals Are Getting Safer for Patients, Study FindsCategory: Health NewsCreated: 7/20/2022 12:00:00 AMLast Editorial Review: 7/20/2022 12:00:00 AM Full Article
are 'Virtual' Museum Visits Are Good Medicine for Seniors By www.medicinenet.com Published On :: Tue, 16 Aug 2022 00:00:00 PDT Title: 'Virtual' Museum Visits Are Good Medicine for SeniorsCategory: Health NewsCreated: 8/16/2022 12:00:00 AMLast Editorial Review: 8/16/2022 12:00:00 AM Full Article
are Bedsores Can Cause Serious Harm — Are U.S. Nursing Homes Hiding Cases? By www.medicinenet.com Published On :: Thu, 18 Aug 2022 00:00:00 PDT Title: Bedsores Can Cause Serious Harm — Are U.S. Nursing Homes Hiding Cases?Category: Health NewsCreated: 8/17/2022 12:00:00 AMLast Editorial Review: 8/18/2022 12:00:00 AM Full Article
are Health Care Plans Keep Allergy Rescue Injectors Pricey for Some By www.medicinenet.com Published On :: Fri, 15 Jul 2022 00:00:00 PDT Title: Health Care Plans Keep Allergy Rescue Injectors Pricey for SomeCategory: Health NewsCreated: 7/15/2022 12:00:00 AMLast Editorial Review: 7/15/2022 12:00:00 AM Full Article
are Pot Users Are Less Prone to Sinus Problems By www.medicinenet.com Published On :: Tue, 2 Aug 2022 00:00:00 PDT Title: Pot Users Are Less Prone to Sinus ProblemsCategory: Health NewsCreated: 8/1/2022 12:00:00 AMLast Editorial Review: 8/2/2022 12:00:00 AM Full Article
are What Are 4 Symptoms of Seasonal Affective Disorder? By www.medicinenet.com Published On :: Wed, 6 Jul 2022 00:00:00 PDT Title: What Are 4 Symptoms of Seasonal Affective Disorder?Category: Diseases and ConditionsCreated: 12/10/2021 12:00:00 AMLast Editorial Review: 7/6/2022 12:00:00 AM Full Article
are Only One Quarter of Family Physicians Are Very Satisfied with Their Electronic Health Records Platform By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Two decades into the era of Electronic Health Records (EHRs), the promise of streamlining clinical care, reducing burden, and improving patient outcomes has yet to be realized. A cross-sectional family physician census conducted by the American Board of Family Medicine in 2022 and 2023 included self-reported physician EHR satisfaction. Of the nearly 10,000 responding family physicians, only one-in-four (26.2%) report being very satisfied and one-in-three (33.8%) were not satisfied. These low levels of satisfaction point to the need for greater transparency in the marketplace and pressure to increase user-centric EHR design. Full Article
are Impact of COVID-19 on Chronic Ambulatory-Care-Sensitive Condition Emergency Department Use Among Older Adults By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: The COVID-19 pandemic social distancing requirements encouraged patients to avoid public spaces including in-office health care visits. Ambulatory-care-sensitive conditions (ACSCs) represent conditions that can be managed with quality primary care and when access is limited, these conditions can lead to avoidable emergency department (ED) visits. Methods: Using national data on ED visits from 2019 to 2021 in the National Hospital Ambulatory Care Survey, we examined the impact of COVID-19 pandemic on ACSC ED visits among older adults (aged ≥65). Results: The proportion of ED visits among older adults that were for ACSCs increased between 2019 (17.4%) and 2021 (18.5%). The trend in both rural (26.4%–28.6%) and urban areas (15.4%–16.8%) shows a significant jump from 2019 to 2021 (P < .001). Conclusions: This rise in ACSC ED use is consistent with a delay in normal primary care during the pandemic. Full Article
are Impact of Point of Care Hemoglobin A1c Testing on Time to Therapeutic Intervention By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Without compromising accuracy, point of care testing (POCT) provides immediate results at the time of in person patient consultation. The purpose of this study was to evaluate time until therapeutic intervention with POCT HbA1c versus venipuncture, where venipuncture was considered standard of care. The primary outcome was time (hours) to implementation of a therapeutic intervention based on POCT HbA1c result, as compared with most recent venipuncture HbA1c before the study and its associated therapeutic intervention. A total of 94 POCT HbA1c tests were included in the primary analysis. For the POCT HbA1c, the mean time to therapeutic intervention was 1.6 ± 3.14 hours. For the previous venipuncture HbA1c, the mean time to therapeutic intervention was 1376.66 ± 3356.6 hours (P < .001). Overall, this trial showed that POCT HbA1c results in a significantly faster time to therapeutic intervention than venipuncture in a primary care clinic that serves a rural population. Full Article
are A Comprehensive Guide to Long-Acting Injectable Antipsychotics for Primary Care Clinicians By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 We propose a paper that provides education on commonly used long-acting injectable antipsychotics (LAIs) to improve primary care based mental health interventions in patients with severe mental illnesses (SMIs) such as schizophrenia, schizoaffective disorder, and bipolar disorders. With the expanding interface of primary care and psychiatry across all healthcare settings, it has become increasingly important for primary care clinicians to have a broader understanding of common psychiatric treatments, including LAIs. Long-acting injectable antipsychotics have been shown to be helpful in significantly improving treatment adherence, preventing disease progression, improving treatment response, decreasing readmission rates, and reducing social impairment. We discuss evidence-based indications and guidelines for use of long-acting injectable antipsychotics. We provide an overview of the treatment of SMI with LAIs, mainly focusing on the most commonly used long-acting injectable antipsychotics, advantages and disadvantages of each, along with outlining important clinical pearls for ease of practical application. Equipped with increased familiarity and understanding of these essential therapies, primary care clinicians can better facilitate early engagement with psychiatric care, promote more widespread use, and thus significantly improve the wellbeing and quality of life of patients with severe mental illness. Full Article
are Assessing Patient Readiness for Hospital Discharge, Discharge Communication, and Transitional Care Management By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: Discharge communication between hospitalists and primary care clinicians is essential to improve care coordination, minimize adverse events, and decrease unplanned health services use. Health-related social needs are key drivers of health, and hospitalists and primary care clinicians value communicating social needs at discharge. Objective: To 1) characterize the current state of discharge communications between an academic medical center hospital and primary care clinicians at associated clinics; 2) seek feedback about the potential usefulness of discharge readiness information to primary care clinicians. Design: Exploratory, convergent mixed methods. Participants: Primary care clinicians from Family Medicine and General Internal Medicine of an academic medical center in the US Intermountain West. Approach: Literature-informed REDCap survey. Semistructured interview guide developed with key informants, grounded in current literature. Survey data were descriptively summarized; interview data were deductively and inductively coded, organized by topics. Results: Two key topics emerged: 1) discharge communication, with interrelated topics of transitional care management and follow-up appointment challenges, and recommendations for improving discharge communication; and 2) usefulness of the discharge readiness information, included interrelated topics related to lack of shared understanding about roles and responsibilities across settings and ethical concerns related to identifying problems that may not have solutions. Conclusions: While reiterating perennial discharge communication and transitional care management challenges, this study reveals new evidence about how these issues are interrelated with assessing and responding to patients’ lack of readiness for discharge and unmet social needs during care transitions. Primary care clinicians had mixed views on the usefulness of discharge readiness information. We offer recommendations for improving discharge communication and transitional care management (TCM) processes, which may be applicable in other care settings. Full Article
are How Early Career Family Medicine Women Physicians Negotiate Their First Job After Residency By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: Nested within a growing body of evidence of a gender pay gap in medicine are more alarming recent findings from family medicine: a gender pay gap of 16% can be detected at a very early career stage. This article explores qualitative evidence of women’s experiences negotiating for their first job out of residency to ascertain women’s engagement with and approach to the negotiation process. Methods: We recruited family physicians who graduated residency in 2019 and responded to the American Board of Family Medicine 2022 graduate survey. We developed a semistructured interview guide following a modified life history approach to uncover women’s experiences through the transitory stages from residency to workforce. A qualitative researcher used Zoom to interview 19 geographically and racially diverse early career women physicians. Interviews were transcribed verbatim and analyzed using NVivo software following an Inductive Content Analysis approach. Results: Three main themes emerged from the data. First, salary was found to be nonnegotiable, exemplified by participants’ inability to change initial salary offers. Second, the role of peer support throughout residency and early career was crucial to uncovering and rectifying salary inequity. Third, a pay expectation gap was identified among women from minority and low-income households. Conclusion: To rectify the gender pay gap in medicine, a systems-level approach is required. This can be achieved through various levels of interventions: societally expanding the use of and removing the stigma around parental leave, recognizing the importance of contributions not currently valued by productivity-based payment models, examining assumptions about leadership; and institutionally moving away from fee-for-service systems, encouraging flexible schedules, increasing salary transparency, and improving advancement transparency. Full Article
are Primary Care Clinicians' Interest In, and Barriers To, Medication Abortion By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Purpose: Providing medication abortion in the primary care setting is a promising way to increase access to abortion, a threatened service in many States. This study aimed to characterize primary care clinicians’ interest in prescribing medication abortion, what barriers they face in adding this service, and what support they need. Methods: Data were collected from 162 practicing primary care clinicians in Minnesota using an online survey with closed- and open-ended response options. Data were analyzed using descriptive statistics, group comparison analyses, and content analysis for the open-ended questions. Results: Participants represented a diverse range of ages, years in practice, credentials, genders, and urban/rural practice settings, and held mixed knowledge and attitudes around medication abortion. All demographic groups surveyed expressed interest in prescribing medication abortion, with the strongest interest represented among younger respondents, women, and those practicing in urban settings. Clinicians who provide prenatal care or who already work with these medications in other contexts were more likely to want to add medication abortion to their practices. The most common barrier to providing medication abortion was a lack of knowledge about organizational policies and about the medications themselves. To empower clinicians to provide medication abortion, respondents voiced needing their health systems to build clear processes and wanting supportive networks of other clinicians for collaboration. Conclusions: Given the interest of primary care clinicians in providing medication abortion, health systems have a valuable opportunity to increase access. Full Article
are A Qualitative Analysis of a Primary Care Medical-Legal Partnership: Impact, Barriers, and Facilitators By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: Certain health-related risk factors require legal interventions. Medical-legal partnerships (MLPs) are collaborations between clinics and lawyers that address these health-harming legal needs (HHLNs) and have been shown to improve health and reduce utilization. Objective: The objective of this study is to explore the impact, barriers, and facilitators of MLP implementation in primary care clinics. Methods: A qualitative design using a semistructured interview assessed the perceived impact, barriers, and facilitators of an MLP, among clinicians, clinic and MLP staff, and clinic patients. Open AI software (otter.ai) was used to transcribe interviews, and NVivo was used to code the data. Braun & Clarke’s framework was used to identify themes and subthemes. Results: Sixteen (n = 16) participants were included in this study. Most respondents were women (81%) and white (56%). Four respondents were clinic staff, and 4 were MLP staff while 8 were clinic patients. Several primary themes emerged including: Patients experienced legal issues that were pernicious, pervasive, and complex; through trusting relationships, the MLP was able to improve health and resolve legal issues, for some; mistrust, communication gaps, and inconsistent staffing limited the impact of the MLP; and, the MLP identified coordination and communication strategies to enhance trust and amplify its impact. Conclusion: HHLNs can have a significant, negative impact on the physical and mental health of patients. Respondents perceived that MLPs improved health and resolved these needs, for some. Despite perceived successes, integration between the clinical and legal organizations was elusive. Full Article
are Associations Between Patient/Caregiver Trust in Clinicians and Experiences of Healthcare-Based Discrimination By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: Higher trust in healthcare providers has been linked to better health outcomes and satisfaction. Lower trust has been associated with healthcare-based discrimination. Objective: Examine associations between experiences of healthcare discrimination and patients’ and caregivers of pediatric patients’ trust in providers, and identify factors associated with high trust, including prior experience of healthcare-based social screening. Methods: Secondary analysis of cross-sectional study using logistic regression modeling. Sample consisted of adult patients and caregivers of pediatric patients from 11 US primary care/emergency department sites. Results: Of 1,012 participants, low/medium trust was reported by 26% identifying as non-Hispanic Black, 23% Hispanic, 18% non-Hispanic multiple/other race, and 13% non-Hispanic White (P = .001). Experience of any healthcare-based discrimination was reported by 32% identifying as non-Hispanic Black, 23% Hispanic, 39% non-Hispanic multiple/other race, and 26% non-Hispanic White (P = .012). Participants reporting low/medium trust had a mean discrimination score of 1.65/7 versus 0.57/7 for participants reporting high trust (P < .001). In our adjusted model, higher discrimination scores were associated with lower trust in providers (aOR 0.74, 95%CI = 0.64, 0.85). A significant interaction indicated that prior healthcare-based social screening was associated with reduced impact of discrimination on trust: as discrimination score increased, odds of high trust were greater among participants who had been screened (aOR = 1.28, 95%CI = 1.03, 1.58). Conclusions: Patients and caregivers reporting more healthcare-based discrimination were less likely to report high provider trust. Interventions to strengthen trust need structural antiracist components. Increased rapport with patients may be a potential by-product of social screening. Further research is needed on screening and trust. Full Article
are Using Primary Health Care Electronic Medical Records to Predict Hospitalizations, Emergency Department Visits, and Mortality: A Systematic Review By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Introduction: High-quality primary care can reduce avoidable emergency department visits and emergency hospitalizations. The availability of electronic medical record (EMR) data and capacities for data storage and processing have created opportunities for predictive analytics. This systematic review examines studies which predict emergency department visits, hospitalizations, and mortality using EMR data from primary care. Methods: Six databases (Ovid MEDLINE, PubMed, Embase, EBM Reviews (Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Methodology Register, Health Technology Assessment, NHS Economic Evaluation Database), Scopus, CINAHL) were searched to identify primary peer-reviewed studies in English from inception to February 5, 2020. The search was initially conducted on January 18, 2019, and updated on February 5, 2020. Results: A total of 9456 citations were double-reviewed, and 31 studies met the inclusion criteria. The predictive ability measured by C-statistics (ROC) of the best performing models from each study ranged from 0.57 to 0.95. Less than half of the included studies used artificial intelligence methods and only 7 (23%) were externally validated. Age, medical diagnoses, sex, medication use, and prior health service use were the most common predictor variables. Few studies discussed or examined the clinical utility of models. Conclusions: This review helps address critical gaps in the literature regarding the potential of primary care EMR data. Despite further work required to address bias and improve the quality and reporting of prediction models, the use of primary care EMR data for predictive analytics holds promise. Full Article
are Family Medicine Must Prepare for Artificial Intelligence By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Artificial Intelligence (AI) is poised to revolutionize family medicine, offering a transformative approach to achieving the Quintuple Aim. This article examines the imperative for family medicine to adapt to the rapidly evolving field of AI, with an emphasis on its integration in clinical practice. AI's recent advancements have the potential to significantly transform health care. We argue for the proactive engagement of family medicine in directing AI technologies toward enhancing the "Quintuple Aim." The article highlights potential benefits of AI, such as improved patient outcomes through enhanced diagnostic tools, clinician well-being through reduced administrative burdens, and the promotion of health equity by analyzing diverse data sets. However, we also acknowledge the risks associated with AI, including the potential for automation to diverge from patient-centered care and exacerbate health care disparities. Our recommendations stress the need for family medicine education to incorporate AI literacy, the development of a collaborative for AI integration, and the establishment of guidelines and standards through interdisciplinary cooperation. We conclude that although AI poses challenges, its responsible and ethical implementation can revolutionize family medicine, optimizing patient care and enhancing the role of clinicians in a technology-driven future. Full Article
are Nocturnal Pressure Support Ventilation: Truth or Dare? By rc.rcjournal.com Published On :: 2024-10-25T05:44:13-07:00 Full Article
are The Evolution of Intermittent Mandatory Ventilation: Update and Implications for Home Care By rc.rcjournal.com Published On :: 2024-10-25T05:44:13-07:00 Full Article
are Improving Patient Outcomes through the Diagnostic and Care Planning Process By jdh.adha.org Published On :: 2024-10-15T09:18:40-07:00 Full Article
are Development and Validation of a Customized Amplex UltraRed Assay for Sensitive Hydrogen Peroxide Detection in Pharmaceutical Water By journal.pda.org Published On :: 2024-10-22T08:20:35-07:00 For clean-room technologies such as isolators and restricted access barrier systems (RABS), decontamination using hydrogen peroxide (H2O2) is increasingly attractive to fulfill regulatory requirements. Several approaches are currently used, ranging from manual wipe disinfection to vapor phase hydrogen peroxide (VPHP) or automated nebulization sanitization. Although the residual airborne H2O2 concentration can be easily monitored, detection of trace H2O2 residues in filled products is rather challenging. To simulate the filling process in a specific clean room, technical runs with water for injection (WfI) are popular. Thus, the ability to detect traces of H2O2 in water is an important prerequisite to ensure a safe and reliable use of H2O2 for isolator or clean room decontamination. The objective of this study was to provide a validated quantitative, fluorometric Amplex UltraRed assay, which satisfies the analytical target profile of quantifying H2O2 in WfI at low nanomolar to low micromolar concentrations (ppb range) with high accuracy and high precision. The Amplex UltraRed technology provides a solid basis for this purpose; however, no commercial assay kit that fulfills these requirements is available. Therefore, a customized Amplex UltraRed assay was developed, optimized, and validated. This approach resulted in an assay that is capable of quantifying H2O2 in WfI selectively, sensitively, accurately, precisely, and robustly. This assay is used in process development and qualification approaches using WfI in H2O2-decontaminated clean rooms and isolators. Full Article
are The area postrema: a critical mediator of brain-body interactions [Special Section: Symposium Outlook] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 The dorsal vagal complex contains three structures: the area postrema, the nucleus tractus solitarii, and the dorsal motor nucleus of the vagus. These structures are tightly linked, both anatomically and functionally, and have important yet distinct roles in not only conveying peripheral bodily signals to the rest of the brain but in the generation of behavioral and physiological responses. Reports on the new discoveries in these structures were highlights of the symposium. In this outlook, we focus on the roles of the area postrema in mediating brain–body interactions and its potential utility as a therapeutic target, especially in cancer cachexia. Full Article
are The treatment of latent tuberculosis infection in migrants in primary care versus secondary care By erj.ersjournals.com Published On :: 2024-11-07T00:35:56-08:00 Extract With a disproportionate burden of tuberculosis (TB) amongst migrants in Europe [1], Burman et al. [2] have highlighted the pressing need for alternative approaches to make TB infection (TBI) screening comprehensive and accessible. Across high-income Organisation for Economic Co-operation and development countries, a median of 52% of TB cases occur in foreign-born individuals, who are at their highest risk of developing TB disease within the first 5 years of migration [3]. Molecular epidemiological studies indicate that the majority of these cases occur as a result of TBI reactivation, often acquired overseas [4]. Within the UK, overseas-born migrants have a 14-fold higher TB incidence than UK-born individuals [5]. The World Health Organization therefore recommends that migrants from countries with a high TB burden may be prioritised for TBI screening [6, 7]. Full Article
are Treatment of latent tuberculosis infection in migrants in primary care versus secondary care By erj.ersjournals.com Published On :: 2024-11-07T00:35:55-08:00 Background Control of latent tuberculosis infection (LTBI) is a priority in the World Health Organization strategy to eliminate TB. Many high-income, low TB incidence countries have prioritised LTBI screening and treatment in recent migrants. We tested whether a novel model of care, based entirely within primary care, was effective and safe compared to secondary care. Methods This was a pragmatic cluster-randomised, parallel group, superiority trial (ClinicalTrials.gov: NCT03069807) conducted in 34 general practices in London, UK, comparing LTBI treatment in recent migrants in primary care to secondary care. The primary outcome was treatment completion, defined as taking ≥90% of antibiotic doses. Secondary outcomes included treatment acceptance, adherence, adverse effects, patient satisfaction, TB incidence and a cost-effectiveness analysis. Analyses were performed on an intention-to-treat basis. Results Between September 2016 and May 2019, 362 recent migrants with LTBI were offered treatment and 276 accepted. Treatment completion was similar in primary and secondary care (82.6% versus 86.0%; adjusted OR (aOR) 0.64, 95% CI 0.31–1.29). There was no difference in drug-induced liver injury between primary and secondary care (0.7% versus 2.3%; aOR 0.29, 95% CI 0.03–2.84). Treatment acceptance was lower in primary care (65.2% (146/224) versus 94.2% (130/138); aOR 0.10, 95% CI 0.03–0.30). The estimated cost per patient completing treatment was lower in primary care, with an incremental saving of GBP 315.27 (95% CI 313.47–317.07). Conclusions The treatment of LTBI in recent migrants within primary care does not result in higher rates of treatment completion but is safe and costs less when compared to secondary care. Full Article
