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Discovery of new poppy enzyme might help improve yeast-based opiate synthesis

Adding enzyme to engineered yeast boosts production of thebaine, a key morphine intermediate




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Lonza consolidates its New Jersey R&D




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Scientists push back against Trump administration’s proposed visa rules




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U.S. industries ask Trump administration to endorse global hydrofluorocarbon deal

With EPA regulation overturned in court, companies seek political backing for reducing HFC use domestically




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DowDuPont CEO favors short-term R&D

Ed Breen wants to avoid the uncertainty and expense of “moonshot” projects




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This chili pepper compound will self-destruct

To relieve itch and pain without undesirable side effects, chemists put a kill switch on capsaicin




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DowDuPont CEO favors short-term R&D

Ed Breen wants to avoid the uncertainty and expense of moonshot projects




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Recycling needs a revamp

Chemical and biochemical approaches take aim at plastic pollution




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Chemistry Olympiad Study Camp begins




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ACS Nigeria Chapter hosts symposium in Uyo




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Alexion partners with Complement Pharma on neurodegenerative therapy




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Cambrex expanding generics R&D in Italy




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Chili pepper compound made to self-destruct

To relieve itch and pain without worrisome side effects, chemists put a kill switch on capsaicin




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Un dispositivo hace más fácil y segura la transferencia de <i>terc</i>-butil litio y otros compuestos químicos pirofóricos

Las piezas reducen de forma sencilla el peligro al transferir pequeños volúmenes de productos químicos inflamables




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Start-up Olaplex triumphs over L’Oréal in court case




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Trump proposes U.S. federal government reorganization

Food regulation, graduate education among changes put forward




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BridgeBio licenses compounds from NeuroVive and launches Fortify Therapeutics




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U.S. team finalized for International Chemistry Olympiad

4 high school students will head to Slovakia and Czech Republic in July for international competition




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Acknowledging the spies on campus

As universities embrace rapid communications and international students, they are learning that the free exchange of ideas comes with risks




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Dow materials used in new Olympic headquarters




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Non-addictive opiate-like compounds may help treat narcolepsy

Chronic morphine treatment in mice restored a narcolepsy-related deficit in the brain, decreasing symptoms 




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C&EN wins EXCEL Awards




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Ex-Chemours employee admits guilt




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Errors in C&EN graphic reveal widespread misconceptions about slime chemistry

Multiple sources, including journal articles and chemical catalogs, get the borate bonding and reactivity wrong




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Characterizing compounds released from single-use plastic bags

The biomanufacturing alternatives to metal vats release different molecules depending on age and type of material




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Trump’s tweets prompt Pfizer to postpone drug price hikes

The president deemed the price rollback a victory, but industry watchers say Pfizer could benefit in the long run




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Compass Therapeutics debuts with $132 million in funding




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Novartis to end anti-infectives R&D




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Empowering a sustainable world

These members of the new guard of scientists are using systems thinking to make green chemistry mainstream




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South Korea’s SK to acquire Ampac Fine Chemicals




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U.S. team heads to International Chemistry Olympiad




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To improve reproducibility in the lab, these chemists press ‘record’

Using GoPros and other inexpensive cameras, researchers are documenting their experimental procedures




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Ruthenium could rewire computer chips

As chip components continue to shrink, the semiconductor industry explores alternatives to today’s copper connectors to avoid electrical problems




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Supramolecular complex liberates lithium

Cation gets a conductivity boost by capturing its counterion




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Low-dose aspirin improves memory in mice with Alzheimer’s symptoms

Study suggests activating PPAR receptor leads to increased cellular connections in hippocampus




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Entrepreneurs get in on the ground floor with CBD from hemp

Growing this cousin of marijuana could help boost local farm economies




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To improve reproducibility in the lab, these chemists press ‘record’

Using GoPros and other inexpensive cameras, researchers are documenting their experimental procedures




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FDA considers imports to tackle high U.S. drug prices




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C&EN’s Global Top 50 chemical companies

Chemical profits continue to rise as the global economy booms




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U.S. team wins 4 golds at the International Chemistry Olympiad

Winning streak continues as high school students turn in a top performance for the second year in a row




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U.S. team wins 4 golds at the International Chemistry Olympiad

Winning streak continues as high school students turn in a top performance for the second year in a row




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Metrohm buys spectroscopy specialist B&W Tek




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Will the improving crude oil market sentiment last?

After an yo-yo movement in crude oil market last three weeks, including negative prices for the US-centric WTI (West Texas Intermediate), there is no




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BSE, NSE launch rupee-dollar F&O contracts at GIFT city

The BSE and the National Stock Exchange have launched Rupee-Dollar futures and options contracts on their international exchange platforms based at th




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Honda Jazz, a compact with sedan-like practicality

Although this segment has way too many offerings and the Jazz is one of the most expensive options, people looking for a reliable and spacious hatchback will not be disappointed by this vehicle.




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Company performance vs CEO salary: Explained in charts

Mid and small companies are more generous in rewarding their CEOs as compared to their larger peers.




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Elegant 330i M Sport is an improvement on BMW's best

Spend a weekend with the BMW 330i M Sport and it becomes apparent that plenty of fresh elements have been injected into the new 3 Series, says Pavan Lall.




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Why Body Shop launched 1st global TV campaign in India

The Body Shop has a compelling ethical message behind the branding of its products, and its new piece of communication in India -- the first ever television commercial shot in any country -- takes that strategy forward, reports T E Narasimhan.




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How L&amp;T's cyclone warning system beat Fani in Odisha

Powered by solar panels and equipped with the latest technologies, the system remained up even when strong winds crippled mobile services and felled electric poles, writes Jayajit Dash.




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Toronto Stock Exchange Company Manual

In partnership with the Toronto Stock Exchange (TSX), Wolters Kluwer has been publishing the printed version of the Toronto Stock Exchange Company Manual for over 10 years. We are pleased to be able to continue to publish it and provide you with the most up-to-date text of this invaluable resource.

As Canada's senior equities market, the TSX provides an efficient, liquid market for a broad cross-section of Canadian issuers. The TSX assists about 1500 issuers through services designed to increase retail and institutional investors. Whether your company is listed or considering listing on the TSX, this manual is the most comprehensive source of compliance information that you will need.

It includes practical information such as forms, including those needed to apply for listing, and the private placement questionnaire. It is updated by the TSX as required and you will receive these updates as part of your annual subscription service. It also gives you all the information you need to know about listing and maintaining a listing on the TSX, including:

  • Benefits of a TSX listing
  • The listing process
  • Responsibilities of companies once listed
  • Suspension and delisting criteria
  • TSX timely disclosure policy and guidelines for dealing with the media

Included with your subscription is the monthly newsletter Canadian Securities Law News, that summarizes all recent developments in securities regulation across Canada.


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