A new study has combined two research methods to assess the risk of pesticide contamination within a river basin and identify locations of risk. Six groups of pesticides were identified in a French river basin and one specific area was labelled as 'high risk' due to intense agriculture.

Researchers have developed the first biology-based model to predict the sub-lethal effects of chemical mixtures on organisms. Sub-lethal effects do not cause death but can damage processes such as growth and reproduction. The model provided accurate predictions of the sub-lethal impacts of a chemical mixture on water fleas.

Assessing the cumulative human health risk caused by multiple toxic substances is a major challenge. New research has reported on developments in the US, where the Environmental Protection Agency (EPA) is creating a tool that will provide maps and other information to depict exposure data and risks at both a national and a local level.

New research has supported a more thorough integration of toxic mixture assessments into two major pieces of EU legislation: REACH and the Water Framework Directive. It recommended constructing a database of harmful chemicals in the environment which, among other uses, could assess mixture toxicity using a 'Concentration Addition' method.

In line with EU legislative requirements, new research has developed models to assess the toxicity of chemicals in terms of their effects on human development. One of the models has been made freely accessible online, so that it is easy to use for industry and regulators.

A new approach to assessing the risk posed by 500 organic chemicals potentially found in the surface waters of river basins across Europe has been developed. It allows pollutants of concern, including emerging substances, to be identified and prioritised by Member States for monitoring and action as required by the Water Framework Directive.

A recent study has considered the levels at which active pharmaceutical ingredient (API) residues are safe when released into water bodies from drug manufacturing plants. It proposes that environmental reference concentrations and maximum tolerable concentrations are adopted for each API.

Comparative toxic assessments across regions and countries are needed to minimise human exposure to harmful chemicals associated with consumer products. A new study has developed a US version of the EU Toxic Potential Indicator (TPI) and compared the two models for over 500 chemicals. Differences in results exist, indicating a need for more harmonisation between regulatory thresholds and guidelines.

Debate exists as to whether environmental concentrations of the hazardous substance hexachlorobenzene (HCB) should be measured in water or in wildlife when assessing compliance with environmental quality standards (EQS). New research has proposed a method to calculate concentrations in water that best represent critical levels in wildlife, and a tiered approach to compliance assessment that minimises sampling of wildlife.

A risk-based tool built using multi-criteria decision analysis has been developed to rank environmental contaminants, giving each a level of concern. It can be used by decision makers to prioritise areas for further assessments, based on expected human health impacts.

The Deepwater Horizon oil spill is likely to have damaged large numbers of tuna and amberjack fish embryos, new research suggests. Fish embryos exposed to oil samples taken during the spill developed abnormalities in their hearts and, consequently, their spines, fins and eyes. This is likely to have caused population declines in these commercially important species, the researchers conclude.

Mercury and persistent organic pollutants (POPs) reduce albatrosses’ chances of successfully breeding, a recent study finds. These pollutants add to the list of environmental pressures, including climate change, disease and fishery bycatch, affecting this highly threatened species.

Combining steam with heat-producing chemicals could control pathogenic viruses in soil, finds new research. The study examined how effective different forms of heat sterilisation of soil were at inactivating three plant viruses. While steam alone was enough to eradicate two of the viruses, the highly resilient tobacco mosaic virus required the addition of exothermic chemicals to reduce it by 97%.

Disposable components of Electronic Nicotine Delivery Systems (ENDS), such as e-cigarettes and e-pens, could pose a potential environmental risk unless properly regulated, suggests new research. The study examined the levels of potentially toxic chemicals in disposable battery and 'cartomiser' ENDS components.

Concentrations of three pharmaceuticals (ethinylestradiol, oestradiol and diclofenac), have been mapped in a recent study of European rivers. The researchers predict that levels of ethinylestradiol, a contraceptive and hormone replacement drug, could exceed the WFD's suggested environmental quality standards in 12% of the total length of Europe’s rivers

Weathering and abrasion are reported to cause titanium dioxide nanoparticles to escape from a self-cleaning coating for buildings. These particles may be toxic to humans and wildlife. The researchers have developed three indicators from the test results to help predict levels of nanoparticle release from these coatings.

Intersex fish, in which male reproductive tissues become ‘feminised’, are increasingly being identified. This effect has traditionally been attributed to birth-control medications. This study exposed fish to a widely prescribed anti-diabetic, metformin. Male fish developed female sexual characteristics and reproductive rate decreased, which suggests that metformin may be a non-traditional endocrine-disrupting compound.

Environmental risk assessment is challenging because of the complexity of the physical and ecological systems around us. Natural disasters, the spread of dangerous substances, ecosystem changes leading to food and health security issues, and the emergence of new materials, new events and new knowledge make it essential to update our understanding continually, to be able to identify threats and opportunities for timely action. This Thematic Issue presents some collaborative and integrated paths towards forward-thinking assessment and management of environmental risks.

New research has combined two different techniques for identifying hazards and assessing risks into a single dynamic risk assessment process. The new approach fills a gap in many current risk assessment techniques as it can be applied throughout the lifetime of a process, not just during its design phase, taking into account new information to update risk assessments and calculations systematically.

A methodology for assessing ‘chemical footprints’ has been developed by researchers to evaluate human pressures and the impact of chemicals released by the production and consumption of goods. The study integrates a life-cycle approach with different methodologies, such as those developed in the context of environmental risk assessment and sustainability science, with the aim of assessing the extent to which chemicals impact on ecosystems beyond their ability to recover (i.e. surpass planetary boundaries).

Chemicals regulation in Europe could be improved through integrated risk assessment, says an EU project. The project team presents a range of perspectives on how the integration of hazard, exposure and socio-economic assessments can be promoted and implemented.

To assess the risk posed by metals in the aquatic environment, Biotic Ligand Models (BLMs) were developed, and are now considered suitable for use in regulatory risk assessments. This study reviews the advantages of BLMs and BLM-based software tools, providing examples from across the EU, and offers recommendations for their widespread implementation.

The use of two methods to systematise evidence-evaluation methods is reviewed in nine EU regulations dealing with chemicals risk assessment. The majority of frameworks were found to promote the use of ‘weight of evidence’ or ‘systematic review’-style approaches, but the study found a lack of structured, consistent and detailed guidance for these approaches. The researchers recommend this guidance is developed collaboratively by European regulatory agencies and points to best practice for this guidance.

Chemicals are everywhere and new substances are regularly being introduced to the market. However, only some pose a risk to the environment. How do we decide which of them to monitor? A new study using a database of chemicals found in fish in the Baltic Sea has assessed which chemicals are commonly monitored. The researchers suggest that monitoring is biased towards known, already regulated hazardous chemicals, and recommend changes to address other chemicals.

A method for developing ecological scenarios for assessing pesticides’ risks to aquatic wildlife has been developed. It is based on the selection of vulnerable taxa according to biological trait information, exposure conditions and environmental properties. The method should help decision makers define what to include in ecological models used for future pesticide risk assessments and is proposed as a way to increase the ecological realism of pesticide risk assessment.

Sources of biocidal active substances (BAS) in common household products have been assessed in a new study from Germany. These could potentially be released into wastewater and may be toxic to wildlife and humans. The main household sources of BAS were found to be washing, cleaning and personal-care products, which together accounted for over 90% of the observations of BAS in the products found in homes surveyed by the researchers.

A recent study has evaluated frameworks and tools used in Europe to assess the potential health and environmental risks of manufactured nanomaterials. The study identifies a trend towards tools that provide protocols for conducting experiments, which enable more flexible and efficient hazard testing. Among its conclusions, however, it notes that no existing frameworks meet all the study’s evaluation criteria and calls for a new, more comprehensive framework.

Judging whether to replace a hazardous conventional chemical in a product with a nanomaterial — i.e. to assess which is the safer alternative — is challenging for many reasons. A new study suggests that chemical-alternative assessment frameworks could be adapted to better assess engineered nanomaterials with the help of new tools which provide data on hazards of, and exposure to, nanomaterials.

Evaluating the level of danger to human health from exposure to multiple chemicals in contaminated sites is a complex task. To address this difficulty, researchers have developed a new screening tool that can be incorporated into public health risk assessment, which may include polluted former industrial plants, waste dumps, or even land where pesticides have been used. This ‘hazard index’ approach indicates when risk to health is high, which organs are most affected, and where further evaluation should be conducted in the context of environmental or occupational exposure at such sites.

Neonicotinoids are pesticides applied to plants to protect them from insects. The use of neonicotinoids may lead to contamination of aquatic environments through, among other routes, the input of contaminated plant material into waterways. While it is well established that direct exposure to contaminated water endangers aquatic invertebrates, scientists have now published findings indicating that dietary exposure through the consumption of contaminated plant material puts leaf-shredding species at increased risk. The researchers recommend that policymakers registering systemic insecticides (those whose active ingredients are transported throughout the plant tissues) consider dietary exposure, and its potential implications for ecosystem integrity, in addition to other exposure pathways.

According to most EU legislation, regulatory assessment of chemicals should make use of all available and relevant studies. However, in practice, assessments tend to be predominantly based on research sponsored and provided by industry as part of their legal obligations to show safety of their products, rather than on independent peer-reviewed findings. To bridge this science–policy gap, a team of Swedish researchers, in combination with regulators at three Swedish governmental agencies, have published a list of recommendations aimed at increasing the regulatory usability and impact of academic research. This advice is aimed at researchers, for whom it clarifies relevant regulatory data requirements and quality criteria. However, it is also relevant to policymakers, in that it highlights the advantages and availability of relevant, reliable peer-reviewed research for use in the regulatory assessment of chemicals. The study’s recommendations contribute to the formulation of more science-based, sustainable policies.

The presence of disinfection by-products (DBPs) in drinking water is an emerging health concern. DBPs come in many classes and are chemically diverse, making them challenging to monitor. Swedish researchers have evaluated a new method for the simultaneous determination of a broader range of DBPs than typically possible using other available techniques. The method uses gas chromatography (a laboratory technique that separates and analyses vaporisable compounds in a mixture), together with a halogen-specific detector (XSD). Having been tested in real water samples from two municipal waterworks in Sweden, the method has been optimised for the simultaneous determination of a wide range of neutral DBPs.

Environmental pollution is putting amphibians and reptiles at risk, yet these animals are not included in regulations regarding the environmental risk assessment (ERA) of pesticides. The extent to which other species already used in pesticide toxicity assessment (including fish, birds and mammals) can serve as effective surrogates is currently under debate. This study conducts a systematic review of the available literature. The results reveal a positive correlation between toxicity recorded on fish and aquatic amphibians, but indicate that birds and mammals are generally not good surrogates for reptiles and terrestrial amphibians. Moreover, some chemical-dependent trends were detected, with a number of insecticides found to be more toxic to amphibians or reptiles than to potential surrogates. These findings highlight an urgent need for further research to reduce uncertainties and contribute to future policymaking regarding the protection of amphibians and reptiles from potentially harmful pesticides.

Contamination of the aquatic environment by pharmaceutical drugs used in human and veterinary medicine is an emerging issue, as it can cause toxic effects in biological systems. This study explored how the marine organism Hediste diversicolor, a polychaete worm, responded to exposure to salicylic acid, a key component of aspirin. They found the species to adapt and respond in a way that minimised the effects of metabolising the contaminating compound, suggesting that the acid does not currently pose a threat to marine polychaetes.

Assessing the impact of large urban areas on air quality and climate change needs an integrated approach with a range of spatial and temporal scales, according to researchers. The EU-funded MEGAPOLI project considers time scales from seconds to decades and spatial scales from local to global.

The quality of indoor air varies widely across Europe, according to a recent study. However, more data are needed from a range of locations, especially in towns and cities, and greater harmonisation of sampling and analysis procedures are needed to develop a more comprehensive picture of European indoor air quality.

The quality of indoor air varies widely across Europe, according to a recent study. Poor indoor air quality is mainly due to household products, outdoor pollution and smoking yielding high levels of organic pollutants harmful to human health. The study indicates higher levels of indoor air pollution in southern Europe than in northern Europe, and with an associated risk of cancer higher than the acceptable unit risk. However the present data must be improved in order to get more precise risk estimates

A study in the Czech Republic has found a link between exposure to certain air pollutants and an increase in DNA damage for people exposed to high levels of the pollution. They found that breathing small quantities of a polycyclic aromatic hydrocarbon (PAH), called benzo[a]pyrene (B[a]P), caused an increase in the number of certain ‘biomarkers’ in DNA associated with a higher risk of diseases, including cancer.

A fast and reliable method to measure the environmental impact of landfill sites has been developed by researchers. Analysis of the chemical composition of gas emissions and water leaching from sites provides a detailed picture of the extent of environmental pollution around landfill sites. Such monitoring is essential in order to manage risks to human health and natural resources.

Inhaling volcanic ash could weaken the body’s natural defences against infection, a recent study concludes. A team of researchers collected samples of ash from the 2010 Eyjafjallajökull volcano eruption in Iceland and, in laboratory tests, found that they reduced the ability of immune cells in lungs to fight off bacterial infections.

The most up-to-date knowledge and data must be used to assess policy objectives, new research confirms. Studying air pollution environmental quality targets set by the National Emission Ceilings (NEC) Directive1, a new study has shown that if 2001 data are used to assess progress, most such targets appear to have been met. However, more recent and accurate current data show that this may not be the case.

Airborne particulate matter pollution leads to increases in death rates among people with underlying health conditions such as heart disease, according to a new study. The study suggests the effects are mainly related to the air pollution known as PM_{2.5 - particles smaller than 2.5 micrometres (μm). The study is the first to assess the health effects of this type of pollution across several European countries at once.}

PM_2.5 air pollution can have a significant impact on human health, not only for local populations, but also in regions far from its source of emission, shows a new study. The study calculates ‘damage factors’ to human health of PM_2.5 and in different parts of the world.

Deposition of heavy metals and nitrogen is falling across Europe, a new study suggests. The researchers used the levels of these pollutants in mosses as indicators of how deposition has changed from 1990 to 2010. These reductions are likely to be the result of effective air pollution policies, they say.

As well as contributing to the greenhouse effect, aircraft emissions have an important impact on air quality and human health. This study, which quantified the effect of civil aviation emissions across the globe, suggests they could be responsible for 16 000 premature deaths every year, at an annual cost of over €18 billion. The air quality costs of aviation were similar to its climate costs, and over 10 times larger than accident and noise costs.

Congestion charges are an effective means of reducing road traffic, but are often strongly opposed by the public. This study combined quantitative and qualitative methods to explore attitudes towards congestion charging in Spain, finding that opposition is reduced when revenues are spent on environmental improvements.

Health impact assessments (HIAs) provide information on the potential health impacts of policies, and are important for developing regulation on air pollution. In this study, researchers evaluated the metrics currently used in air quality HIAs to provide recommendations for their use in policy.

Different modelling approaches are used to design and assess air quality plans across Europe. This study assessed the strengths and weaknesses of these different approaches. The researchers conclude that a large variety of models is in use, without a preferred or standard model having emerged yet. They identify integrating local-scale and large-scale models and verifying models with measurements as the most important challenges.

A new study has, for the first time, estimated total anthropogenic releases of mercury over the last 4 000 years, up to 2010. Overall, the study estimates that a total of 1 540 000 tonnes of mercury have been released; three-quarters of this since 1850, and 78 times more than was released through natural causes over this period. Therefore, human activity has been responsible for a significant level of contamination, and this inventory can be used to inform and assess mitigation measures. The publication coincides with the ratification of the Minamata Convention on Mercury, and the new EU Mercury Regulation1, which prohibits the export, import and manufacturing of mercury-added products, among other measures.