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Rational design of a lysosome-targeted fluorescent probe for monitoring the generation of hydroxyl radicals in ferroptosis pathways

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RSC Adv., 2024, 14,12864-12872
DOI: 10.1039/D4RA00562G, Paper
Open Access
Lili Zhong, Datian Fu, Jin Xu, Linyan Tan, Haimei Wu, Min Wang
A novel hydrocyanine-based turn-on fluorescence probe HCy-Lyso, with excellent lysosome-targeting ability and ˙OH-responsive efficiency, has been applied for monitoring the variation in lysosomal ˙OH levels during ferroptosis.
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Bioactive O^N^O^ Schiff base appended homoleptic titanium(IV) complexes: DFT, BSA/CT-DNA interactions, molecular docking and antitumor activity against HeLa and A549 cell lines

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RSC Adv., 2024, 14,13062-13082
DOI: 10.1039/D3RA08574K, Paper
Open Access
Sathish Thanigachalam, Madhvesh Pathak
Five new homoleptic derivatives of titanium(IV) have been developed and characterized by physicochemical techniques.
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Self-supplying Cu2+ and H2O2 synergistically enhancing disulfiram-mediated melanoma chemotherapy

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Published On ::

RSC Adv., 2024, 14,13180-13189
DOI: 10.1039/D4RA01075B, Paper
Open Access
Yingqian Gao, Xiaojun Cai, Weijuan Zou, Xiuzhen Tang, Lixian Jiang, Junnian Hao, Yuanyi Zheng, Xinhua Ye, Tao Ying, Ao Li
Disulfiram (DSF) can target and kill cancer cells by disrupting cellular degradation of extruded proteins and has therefore received particular attention for its tumor chemotherapeutic potential.
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1D hollow tubular/2D nanosheet hybrid dimensional porous carbon prepared by one-step carbonization using natural minerals as templates for supercapacitors

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RSC Adv., 2024, 14,13190-13199
DOI: 10.1039/D4RA01873G, Paper
Open Access
Fangfang Liu, Chao Zhang, Weiwei Huang, Lei Chen, Yuanshuang Wang, Jinan Niu, Xiuyun Chuan
1D hollow tubular/2D nanosheet hybrid dimensional porous carbon was synthesized through one-step carbonization using 1D fibrous brucite and 2D layered magnesium carbonate hydroxide as templates.
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Application of automated network generation for retrosynthetic planning of potential corrosion inhibitors

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Mol. Syst. Des. Eng., 2024, 9,352-371
DOI: 10.1039/D3ME00162H, Paper
Lauren M. Lopez, Quan Zhang, Orion Dollar, Jim Pfaendtner, Brent H. Shanks, Linda J. Broadbelt
This work uses automated network generation, specifically the Python-based tool Pickaxe, for retrosynthetic planning towards making potential corrosion inhibitors from a pool of candidate bioprivileged molecules.
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Augmentation of inductive effects through short range intramolecular hydrogen bonds for the improvement of cooperativity of trimeric rosettes

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Mol. Syst. Des. Eng., 2024, 9,345-351
DOI: 10.1039/D4ME00008K, Paper
Andre Nicolai Petelski, Tamara Bundrea, Nélida María Peruchena
Three key design elements improve the binding strength of trimeric rosettes: the direction of hydrogen bonds, the addition of groups with inductive effects, and the presence of ambifunctional intramolecular hydrogen bonds between the substituents.
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Engineering the interaction of short antimicrobial peptides with bacterial barriers

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Mol. Syst. Des. Eng., 2024, Advance Article
DOI: 10.1039/D4ME00021H, Minireview
Open Access
Costanza Montis, Elisa Marelli, Francesco Valle, Francesca Baldelli Bombelli, Claudia Pigliacelli
Designing short antimicrobial peptides and tuning their interaction with bacterial barriers.
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Back to the roots, literally

By www.thehindubusinessline.com
Published On :: Fri, 07 Feb 2020 20:50:45 +0530

Going back to traditional foods could reduce malnutrition and promote livelihood options


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Connecting with a long-forgotten era

By www.thehindubusinessline.com
Published On :: Sat, 22 Feb 2020 10:36:52 +0530

A unique exhibition in Haryana showcased rural life before the advent of modernisation


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Heterogenous catalysis for oxygen tolerant photoredox atom transfer radical polymerization and small-molecule dehalogenation

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Polym. Chem., 2024, 15,4264-4280
DOI: 10.1039/D4PY00899E, Paper
Open Access
Kriti Kapil, Mingkang Sun, Ting-Chih Lin, Hironobu Murata, Grzegorz Szczepaniak, Khidong Kim, Stephen DiLuzio, Jaepil Jeong, Mitchell Baumer, Stefan Bernhard, Tomasz Kowalewski, Krzysztof Matyjaszewski
Heterogeneous photocatalysts (PCs) have garnered attention for their sustainability and cost-effectiveness.
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Rapid formation of antifouling coatings via cation–π interactions

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Polym. Chem., 2024, 15,4465-4473
DOI: 10.1039/D4PY00859F, Paper
Zhicheng Huang, Kaijie Zhao, Shaoyin Wei, Yingxin Hao, Qina Yu, Jingcheng Hao, Jiwei Cui, Peiyu Zhang
Antifouling coatings can be quickly prepared on various substrates through cation–π interactions between copolymers and MPNs. In addition, block copolymers exhibited superior antifouling capabilities compared to random copolymers.
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Combined and rapid detection of anti-Brucella IgG/IgM in clinical samples based on surface-enhanced Raman scattering-lateral flow immunochromatography

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J. Mater. Chem. B, 2024, 12,11012-11024
DOI: 10.1039/D4TB01367K, Paper
Yongwei Zhang, Ziyue Li, Aolin Zhu, Qian Zhang, Hao Zhou, Xuelei Zhou, Tingwei Liu, Chunyan Liu, Hefei Zha, Xin Zhang, Hui Zhao, Jiutong Li, Guodong Lü, Xinxia Li
Brucellosis is a bacterial infectious disease caused mainly by Brucella. Transmission is mainly by contact with infected domestic or wild animals or their excreta.
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High-temperature emulsification coupled with low-temperature gelation for fabrication of agarose microsphere implants with well-controlled size for skin tissue enhancement

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J. Mater. Chem. B, 2024, 12,10983-10993
DOI: 10.1039/D4TB01564A, Paper
Qi Wang, Huiyu Yan, Ying Guo, Bei Tian, Jianxi Xiao
Agarose offers self-gelation, biodegradability, and biocompatibility. We have developed a high-temperature emulsification followed by low-temperature gelation method to create agarose microsphere implants for skin tissue augmentation.
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Phase-separated structures of tunable thermoresponsive and matrix polymers for large-scale temperature monitoring coatings

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J. Mater. Chem. B, 2024, 12,10886-10892
DOI: 10.1039/D4TB01743A, Paper
Risako Shibata, Satoru Matsuda, Hirofumi Kawakubo, Hiroaki Imai, Yuya Oaki
Layered polydiacetylene (PDA) exhibits a thermoresponsive color change. The thermoresponsivity and large-scale coatability are controlled for medical applications by the intercalated guests and matrix polymer, respectively.
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Decellularization of caprine forestomach rumen tissue modified with silver nanowires as an antibacterial skin substitute scaffold in wound care therapeutics

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01560F, Paper
Athmana P. A., Asna Jaleel K. I., Sinduja Malarkodi Elangovan, Riza Paul, Naveen Subbaiyan, Parthiban Shanmugam, Gopal Shankar Krishnakumar
Caprine forestomach native collagen (CFNC) modified with silver nanowires (AgNWs) as a new class of biomimetic xenograft for skin regeneration with strong antimicrobial properties.
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Expression of concern: Surface modification engineering of two-dimensional titanium carbide for efficient synergistic multitherapy of breast cancer

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB90175D, Expression of Concern
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lei Bai, Wenhui Yi, Taiyang Sun, Yilong Tian, Ping Zhang, Jinhai Si, Xun Hou, Jin Hou
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Bioinspired nanovesicles derived from macrophage accelerate wound healing by promoting angiogenesis and collagen deposition

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D3TB02158K, Paper
Tingrui Zhang, Zongguang Tai, Fengze Miao, Yingchao Zhao, Weifan Wang, Quangang Zhu, Zhongjian Chen
We prepared bioinspired nanovesicles by gradient extrusion to replace exosomes for wound healing. The nanovesicles have potential for transformation.
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Intrafibrillar Calcium Carbonate Mineralization of Electrospinning Polyvinyl Alcohol/Collagen Films with Improved Mechanical and Bioactive Properties

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01472C, Paper
Yin Liu, Xin Gao, Yuqi Li, Anqi Gao, Zhuozhi Zheng, Jingjiang Wei, Hongye Yang, Hang Ping, Hao Xie, Hao Wang, Weiming Wang, Zhengyi Fu
Collagen films play an essential role in guided bone regeneration (GBR) techniques, which creat space, promote cell adhesion, and induce osteogenic differentiation. It is therefore crucial to design appropriate GBR...
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Efficient bionic nanozyme based on AuPt NPs@ZIF-90 used for cyclic catalysis multimodal tumor therapy

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01987C, Paper
Wan Huang, Song Zhang, Li Luo, Yalong Pan, Lijun Han, Yao Yu
Novel efficient bionic nanozyme based on AuPt NPs@ZIF-90 used for cyclic catalysis multimodal tumor therapy.
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Electronic band structure modulation for sonodynamic therapy

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01679C, Review Article
Yafang Shi, Chengzhilin Li, Linquan Li, Qingbin He, Qingyi Zhu, Ziang Xu, Yanzi Liu, Nianlei Zhang, Meng Zhang, Jianwei Jiao, Runxiao Zheng
Sonodynamic therapy (SDT) is a burgeoning and newfangled therapy modality with great application potential. Sonosensitizers are most essential factors to ensure the effectiveness of SDT. For the past few years,...
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One-pot rapid preparation of long-term antioxidant and antibacterial biomedical gels based on lipoic acid and eugenol for accelerating cutaneous wound healing

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01844C, Paper
Yungang Feng, Fangrui Xie, Rui Ding, Qingrong Zhang, Youzhi Zeng, Li Li, Lianbin Wu, Yunlong Yu, Linxuan Fang
A medical antibacterial gel with long term and high antioxidant activity prepared from eugenol and lipoic acid showed good tissue repair and regeneration for burns and trauma.
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Scalable fabrication of porous membrane incorporating human extracellular matrix-like collagen for guided bone regeneration

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Published On ::

J. Mater. Chem. B, 2024, 12,11142-11155
DOI: 10.1039/D4TB00962B, Paper
Qingyi Wang, Feng Zhou, Tiecheng Qiu, Yiling Liu, Wenxin Luo, Zhanqi Wang, Haiyun Li, E. Xiao, Qiang Wei, Yingying Wu
We fabricated a PCL/hCol membrane with an asymmetric porous structure for guided bone regeneration via nonsolvent-induced phase separation method. It shows superior mechanical and degradation properties, biocompatibility and osteoinductive effect.
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A near-infrared superoxide generator based on a biocompatible indene-bearing heptamethine cyanine dye

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11202-11209
DOI: 10.1039/D4TB01663G, Paper
Nikita Bel’ko, Anna Mal’tanova, Anastasiya Bahdanava, Anatol Lugovski, Sviatlana Fatykhava, Polina Shabunya, Adam Smaliakou, Sergey Poznyak, Tatsiana Kulahava, Michael Samtsov
A heptamethine cyanine dye with an indene moiety and 4-meso-chloride generates superoxide inside cells upon near-infrared photoactivation, inducing cell death.
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A bilayer hydrogel mimicking the periosteum-bone structure for innervated bone regeneration

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11187-11201
DOI: 10.1039/D4TB01923G, Paper
Wenhui Lyu, Yuyue Zhang, Shaopei Ding, Xiang Li, Tong Sun, Jun Luo, Jian Wang, Jianshu Li, Lei Li
The bilayer hydrogel GS@Mg/GP@Mg in this study is a promising material to promote innervated bone regeneration for functional and structural repair of bone defects.
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A dual-functional photosensitizer for mitochondria-targeting photodynamic therapy and synchronous polarity monitoring

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11259-11264
DOI: 10.1039/D4TB01872A, Paper
Liu Yang, Shenglong Gan, Jie Zhang, Yin Jiang, Qingxin Chen, Hongyan Sun
A dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.
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A simple hydrogen peroxide-activatable Bodipy for tumor imaging and type I/II photodynamic therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11165-11171
DOI: 10.1039/D4TB01650E, Paper
Fangqing Ge, Yujie Sun, Yu Wang, Dan Yu, Zhijia Wang, Fabiao Yu, Bingran Yu, Hongbing Fu
A H2O2-activatable Bodipy with simultaneous type I and type II photosensitization was designed for tumor imaging and therapy.
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Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics

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Published On ::

J. Mater. Chem. B, 2024, 12,11076-11088
DOI: 10.1039/D4TB01930J, Review Article
Vivek Pandey, Tejasvi Pandey
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.
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Breakthrough in cancer therapy: lutetium texaphyrin–celecoxib conjugate for immune and photodynamic treatment

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB02019G, Highlight
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Qihang Ding, Yue Wang, Pengfei Zhang, Ling Mei
Kim et al. present a small-molecule photosensitizer, LuCXB, which combines a COX-2 inhibitor (celecoxib) with a near-infrared lutetium texaphyrin photocatalyst and was loaded CD133-aptamer functionalized exosome for cancer stem cells targeting.
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A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor for synergistic antibacterial therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11105-11109
DOI: 10.1039/D4TB01840K, Communication
Ruixue Han, Kehan Du, Shengke Li, Minzan Zuo, Ponmani Jeyakkumar, Hao Jiang, Leyong Wang, Xiao-Yu Hu
A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor has been successfully constructed for synergistic antibacterial therapy.
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Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00599F, Review Article
Shikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. Varma
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
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Nanomaterial-mediated photothermal therapy modulates tumor-associated macrophages: applications in cancer therapy

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01928H, Review Article
Yan Li, Yuhao Si, Heng Yin
Nanomaterials for modulating tumor-associated macrophages in photothermal therapy.
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Controlled therapeutic cholesterol delivery to cells for the proliferation and differentiation of keratinocytes

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11110-11122
DOI: 10.1039/D4TB01015A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Krzysztof Berniak, Ahmadreza Moradi, Agata Lichawska-Cieslar, Weronika Szukala, Jolanta Jura, Urszula Stachewicz
The research concept involves investigating how cholesterol endocytosis impacts cells using electrospun fibers as a carrier. We studied keratinocyte proliferation and evaluated gene expression levels for markers of early and late differentiation.
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Nanomaterials and methods for cancer therapy: 2D materials, biomolecules, and molecular dynamics simulations

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01667J, Review Article
Welela M. Kedir, Lunna Li, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke
Nanomaterials made from 2D semiconductors and biomolecules are reviewed. Cell-nanoparticle interactions are examined in recent simulations. These nanomaterials and MD simulations reveal novel mechanisms and enable cancer drug delivery and targeting.
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Biomaterials Enhancing Localized Cancer Therapy Activated Anti-Tumor Immunity: A Review

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01995D, Review Article
Jipeng Yao, Zhencun Cui, Feifei Zhang, Haidong Li, Longlong Tian
Localized cancer therapy such as radiotherapy, phototherapy, and chemotherapy are precise cancer treatment strategy, aiming to minimize systemic side effect. However, cancer metastasis remains the primary cause of cancer patients’...
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Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01777C, Paper
Jiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin Pei
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
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Nano-Bio Interactions of Gum Arabic-Stabilized Lanthanide-based Upconverting Nanoparticles: In Vitro and In Vivo Study

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01579G, Paper
Hana Mirmajidi, Hyojin Lee, Niepukolie Nipu, Jith Thomas, Zuzana Gajdosechova, David Kennedy, Jan A. Mennigen, Eva Hemmer
Lanthanide-based nanoparticles (Ln-NPs) are highly valued for their unique optical and magnetic properties, making them useful in various scientific fields, including materials science and biomedicine. This study investigated the use...
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H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01653J, Paper
Qiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai Xu
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
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Nanoparticles based image-guided thermal therapy and temperature feedback

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01416B, Review Article
Carlos Jacinto, Wagner Ferreira Silva, Joel Garcia, Gelo P. Zaragosa, Carlo Nonato De Jesus Ilem, Tasso O. Sales, Harrison D. A. Santos, Blessed Isaac C. Conde, Helliomar Pereira Barbosa, Sonia Malik, Surender Kumar Sharma
Nanoparticles have emerged as versatile tools in the realm of thermal therapy, offering precise control and feedback mechanisms for targeted treatments. This review explores the intersection of nanotechnology and thermal...
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Cuproptosis in cancer therapy: mechanisms, therapeutic application and future prospects

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01877J, Review Article
Jiawei Hu, Junfei Zhu, Tao Chen, Yudie Zhao, Qingwen Xu, Yan Wang
Cuproptosis is a regulated form of cell death induced by the accumulation of metal ions and is closely linked to aspects of cellular drug resistance, cellular metabolism, and signalling pathways.
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MnO2-mineralized milk exosomes as a novel nanoplatform for glutathione detection

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01662A, Paper
Xudong Wang, Xue Wu, Jiuheng Shen, Xian Zhao, Peifen Gao, Wantong Zhou, Wenlin An
This study introduces a novel nanoplatform by surface manganese dioxide (MnO2) mineralization of milk exosomes and labelling with curcumin, enhancing their utility in the detection of GSH.
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Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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Bimetallic doped carbon dot nanozymes for enhanced sonodynamic and nanocatalytic therapy

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01916D, Paper
Yandong Huang, Lanting Jia, Shiqi Zhang, Lan Yan, Lei Li
The conventional inorganic semiconductors are not suitable for acting as nanozymes or sonosensitizers for in vivo therapeutic nanomedicine owing to the lack of excellent biocompatibility. Biocompatible carbon dots (CDs) exhibit...
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Hyderabad rekindles the fire for heritage cuisine

By www.thehindubusinessline.com
Published On :: Wed, 04 Aug 2021 12:26:06 +0530

Nothing about it is quick or simple. Meats need days of marination, spices are ground from scratch, and cooking takes hours. Yet, dishes from the Nizam era are winning new connoisseurs


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Turning the lens on the most iconic camera made in India

By www.thehindubusinessline.com
Published On :: Thu, 19 Aug 2021 11:03:40 +0530

A nostalgic look at the vintage Vageeswari camera invented in Alappuzha — back in focus as it is spotlighted at the ongoing Lokame Tharavadu art event


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Funeral Nights: Hills that speak

By www.thehindubusinessline.com
Published On :: Thu, 09 Sep 2021 09:17:35 +0530

A group of strangers come together to attend a death ceremony and the event throws up fascinating stories on the Khasi way of life


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A lateral strip assay for ultrasensitive detection of glyphosate in soybeans and corn

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Published On ::

Analyst, 2024, 149,5232-5242
DOI: 10.1039/D4AN00958D, Paper
Xuyang Ma, Liqiang Liu, Shanshan Song, Hua Kuang, Chuanlai Xu, Xinxin Xu
The determination of glyphosate in soybean (a) and corn (b) samples using a lateral strip assay.
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Detection of several volatile organic compounds through Ar+ induced chemical ionisation using inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS)

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Analyst, 2024, 149,5174-5183
DOI: 10.1039/D4AN00996G, Paper
Takafumi Hirata, Kyoko Kobayashi, Hui Hsin Khoo, Osamu Shikino, Hisashi Asanuma
A new analytical technique for detection of organic compounds using inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS) is described.
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Alterations of the chemical profile of cholesterol in cancer tissue as traced with ToF-SIMS

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Published On ::

Analyst, 2024, 149,5344-5352
DOI: 10.1039/D4AN01050G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Auraya Manaprasertsak, Julhash U. Kazi, Catharina Hagerling, Kenneth J. Pienta, Per Malmberg, Emma U. Hammarlund
This study uses Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) to analyze cholesterol alterations in cancer tissue, revealing changes in fragmentation and isotopes that suggest potential diagnostic vulnerabilities.
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