Educators are wrestling with tough questions as more schools embrace personalized learning and its accompanying belief in giving students more control over their academic experiences.

Very carefully, experts say, while understanding that federal laws governing special education were not written with online education in mind.

Of the three political upheavals that have hit the Maghreb since the beginning of 2011, the Libyan crisis seems to be the most dangerous. First of all for Libya, because the popular uprising has taken the form of an armed rebellion that has cut the country in two; second, for the West, now that NATO, under the cover of United Nations Resolution 1973 (2011) and in order to protect the civilian population, has entered the conflict on the side of the rebels, rashly gambling on a speedy war; and finally, for the region as a whole, because the conflict recently "overflowed" into Tunisia, and neighbouring countries are beginning to feel its humanitarian consequences.

Despite the establishment of anti-corruption agencies, Burundi is facing a deepening corruption crisis that jeopardises prospects for lasting peace and stability.

The crisis that has been occurring in CAR is certainly the most dramatic in its history: more than 600 000 Central Africans are internally displaced or sought refuge in neighbouring countries; according to the United Nations, 1.7 million live in a constant situation of food insecurity and 878 000 need immediate medical assistance; Muslim communities are fleeing Bangui and the western region, subsistence economy no longer exists and the de facto partition of the country, caused by the sectarian violence, is gradually becoming a reality.

To stabilise the Central African Republic (CAR), the transitional government and its international partners need to prioritise, alongside security, action to fight corruption and trafficking of natural resources, as well as revive the economy.

The image of Cameroon as an island of peace amidst regional turmoil ended in 2013, when Boko Haram’s violence first crossed the Nigerian border. The militant group is affiliated with so-called Islamic State or Daesh, and even renamed itself Islamic State in West Africa earlier this year. But the brutal form of African jihadism it represents is hardly a result of the Islamic State’s rise in Iraq and Syria. In fact, it is in part a consequence of Africa’s changing religious landscape – not least in Cameroon.

The United States, France, and the United Nations are falling into an all too familiar trap in the Central African Republic (CAR) of financing transition elections before armed militias have been disarmed and their communal hold broken. Exclusionary and botched elections could trigger another wave of violence and deepen the crisis.

The deteriorating situation in Burundi is a perfect storm of much that undermines stability in Africa today — presidents seeking impunity and power through dubious new terms, authoritarian regimes muzzling opposition and independent media, regional rivalries stalemating efforts to bring peace and outside powers unwilling or unable to act.

Le 1er juin dernier à Mugamba (province de Bururi), Pierre Nkurunziza a lancé un ultimatum. « Du haut d’une camionnette, micro à la main, sous très haute protection de l’armée et de la police », rapporte l’AFP, le président burundais a ordonné aux insurgés de cette commune du Sud du pays de déposer les armes dans les quinze jours : « Téléphonez à vos frères qui ont pris les armes, dites-leur que nous leur donnons quinze jours pour qu’ils y renoncent […] Quinze jours, pas plus. Dites-leur cela ». Hasard ou préméditation, la fin de cet ultimatum devrait coïncider avec la reprise prévue des discussions à Arusha, en Tanzanie, entre le gouvernement et l’opposition.

Since 2012, single low dose of primaquine (SLDPQ, 0.25mg/kg) has been recommended with artemisinin-based combination therapies, as first-line treatment of acute uncomplicated Plasmodium falciparum malaria, to interrupt its transmission, especially in low transmission settings of multidrug, including artemisinin, resistance. Policy makers in Cambodia have been reluctant to implement this recommendation due to primaquine safety concerns and lack of data on its efficacy.

In this randomized controlled trial, 109 Cambodians with acute uncomplicated P. falciparum malaria received dihydroartemisinin-piperaquine (DP) alone or combined with SLDPQ on the first treatment day. Transmission-blocking efficacy of SLDPQ was evaluated on Days 0, 1, 2, 3, 7, 14, 21, 28 and recrudescence by reverse transcriptase polymerase chain reaction (RT-PCR) (gametocyte prevalence) and membrane-feeding assays with Anopheles minimus mosquitoes (gametocyte infectivity). Without the influence of recrudescent infections, DP+SLDPQ reduced gametocyte carriage 3 fold compared to DP. Of 48 patients tested on Day 0, only three patients were infectious to mosquitoes (~6%). Post-treatment, three patients were infectious: on D14 (3.5%, 1/29), and on the first and seventh day of recrudescence (8.3%, 1/12 for each); this overall low infectivity precluded our ability to assess its transmission blocking efficacy.

Our study confirms effective gametocyte clearance of SLDPQ when combined with DP in multidrug resistant P. falciparum and the negative impact of recrudescent infections due to poor DP efficacy. Artesunate-mefloquine (ASMQ) has replaced DP and ASMQ-SLDPQ has been deployed to treat all P. falciparum symptomatic patients to further support the elimination of multidrug resistant P. falciparum in Cambodia.

As resistance to artemisinins (current frontline drugs in malaria treatment) emerges in south East Asia, there is an urgent need to identify the genetic determinants and understand the molecular mechanisms underpinning such resistance. Such insights could lead to prospective interventions to contain resistance and prevent the eventual spread to other malaria endemic regions. Artemisinin reduced susceptibility in South East Asia (SEA) has been primarily linked to mutations in P. falciparum Kelch-13, which is currently widely recognised as a molecular marker of artemisinin resistance. However, 2 mutations in a ubiquitin hydrolase, UBP-1, have been previously associated with artemisinin reduced susceptibility in a rodent model of malaria and some cases of UBP-1 mutation variants associating with artemisinin treatment failure have been reported in Africa and SEA. In this study, we have employed CRISPR-Cas9 genome editing and pre-emptive drug pressures to test these artemisinin susceptibility associated mutations in UBP-1 in P. berghei sensitive lines in vivo. Using these approaches, we have shown that the V2721F UBP-1 mutation results in reduced artemisinin susceptibility, while the V2752F mutation results in resistance to chloroquine and moderately impacts tolerance to artemisinins. Genetic reversal of the V2752F mutation restored chloroquine sensitivity in these mutant lines while simultaneous introduction of both mutations could not be achieved and appears to be lethal. Interestingly, these mutations carry a detrimental growth defect, which would possibly explain their lack of expansion in natural infection settings. Our work has provided independent experimental evidence on the role of UBP-1 in modulating parasite responses to artemisinin and chloroquine under in vivo conditions.

Despite being aware of the need for discretion when talking about Jesus, Argentinian Cecilia felt no fear while she was in Central Asia.

Despite being aware of the need for discretion when talking about Jesus, Argentinian Cecilia felt no fear while she was in Central Asia.

Penn State Hazleton’s Student Services and Engagement team is continuing to forge personal connections with students while operating under the restrictions in the virtual environment created by the COVID-19 crisis.

Social distancing is forcing school business to be conducted virtually, putting school boards in the difficult spot of making crucial decisions on spending and other issues without the same level of public input.

India, this magical land, has irresistibly captivated crowds of visitors because of definite motives: incredible Indian charms, numerous residues of past ages, and various sacred points for pilgrimage. Tourism in India has always been among the most full-blown spheres of the state's politics. India tourism allows traveling to all the most famous places, you may wish to visit. Among them, there are illustrious palaces and groves, forts built in both oriental and English colonial manners, and...

Very carefully, experts say, while understanding that federal laws governing special education were not written with online education in mind.

Cesar Gomes Victora
Mar 1, 2010; 125:e473-e480
ARTICLES

Students enrolled in a crisis management course are examining the pandemic and its lessons and developing recommendations that the government and even individuals can follow. It's the kind of real-world experience that students can expect to have at Penn State Abington.

Media literacy belongs in science class, insists Media Literacy Now’s Andy Zucker. Here’s how to bring it there.

CNA Staff, Apr 29, 2020 / 04:30 pm (CNA).- Venezuela’s prolonged social, political and economic crisis has only been compounded by the coronavirus pandemic, the archbishop emeritus of Caracas, Cardinal Jorge Urosa Savino, charged Tuesday.

Even before the coronavirus pandemic, Venezuela has been marred by violence and social upheaval under the socialist administration of Nicolas Maduro, with severe shortages of food and medicine, high unemployment, power outages, and hyperinflation. Some 4.5 million Venezuelans have emigrated since 2015.

In response to the threat of the virus, the government imposed a nationwide stay at home order March 17. According to government statistics, to date there have been 329 cases of COVID-19 with ten deaths. The country is ill prepared to handle the crisis, with chronic shortages of medical supplies, and many doctors have left the country.

“The national reality is terrible,” and the government has no answers, Urosa said in an April 28 statement to ACI Prensa, CNA’s Spanish-language news partner.

While the cardinal acknowledged the lockdown has prevented the spread of the virus, he pointed out that “the quarantine has hurt a great many people because the economic, social and logistical conditions in the country weren’t taken into account,” including “the extremely serious problem of the gasoline shortage for transport, especially for food.”

In some cases, crops are rotting in farmers’ fields due to lack of fuel to transport them to market.

Especially hard hit, the cardinal said, are “informal” workers who are paid off the books,  and who are now  “barely surviving,” and only with “the help of family members, social organizations and the Church.”

On April 25, Venezuelan vice president Delcy Rodríguez announced state intervention and oversight of several food supply companies in order to control the prices of 27 products for 180 days.

Urosa criticized the intervention, calling it “an extremely serious mistake, since it will probably result in greater shortages. Price controls are acceptable, but intervening in efficient businesses is not. The government can’t even manage to supply gasoline.” “The state-run petroleum industry has collapsed, and now Venezuelans’ food is in danger!” 

 “The current government doesn’t have any answers for such elementary things such as the extremely serious problem of the gasoline shortage” and runaway inflation. “In the last 40 days, the dollar has doubled in value, which is undoubtedly the fundamental cause of the spike in prices,” the cardinal said.

Urosa decried political persecution, which “has gotten worse since March because amid the quarantine, the government has ramped up the repression. During these weeks the government has jailed, even without due process, many political activists, especially from the inner circle of Juan Guaidó, president of the National Assembly and leader of the Venezuelan opposition.”

Guaidó declared himself the nation's interim leader Jan. 23 last year following Maduro’s inauguration for a second term. Maduro won a May 2018 presidential election, which was boycotted by the opposition and has been rejected by much of the international community. The United States was swift to recognize Guaidó as interim president, eventually followed by over 60 countries. Both the National Assembly and the Venezuelan bishops' conference declared Maduro's reelection to be invalid.

With the military firmly in support of Maduro, however, opposition protests calling for his resignation have failed to oust the leader.

On March 30, Guaidó charged that the Maduro regime had unleashed a new wave of harassment against his close collaborators. Andrea Bianchi, the wife of close associate Rafael Rico, was kidnapped, beaten and then left naked on a highway. Two others, Rómulo García and Víctor Silio were also picked up and later charged with possession of marijuana and a handgun.

The NGO Venezuelan Program for Education-Action in Human Rights reported that during the state of emergency, 34 people have been arbitrarily arrested and attacks against politicians, journalists and healthcare workers have increased.

“The bishops have always strongly criticized the political repression by the government and once again I call for the release of all political prisoners. They are even in greater physical danger because of the pandemic situation we’re going through,” Urosa stressed.

On March 26, “the Trump administration unsealed sweeping indictments against Venezuelan President Nicolás Maduro and members of his inner circle on narcoterrorism charges, a dramatic escalation in the U.S. campaign to force the authoritarian socialist from power,” even offering “a $15 million reward for information leading to his capture or conviction,” the Washington Post reported.

In response, the Maduro regime activated a plan against the Venezuelan opposition called “Operation Bolivarian Fury.”

The archbishop emeritus denounced these recent “threats of violence by the government against Venezuelans. Maduro himself has spoken of a supposed ‘Bolivarian fury’ as a threat against members of the Venezuelan opposition in case of international problems. That’s illegal, unconstitutional and unacceptable from every point of view. That threat of violence is intolerable.” 

The cardinal said the government has used the quarantine simply as an opportunity to strengthen its social and political control.

On April 25, the Maduro regime placed shipping containers on the Caracas-La Guaira highway to prevent demonstrators from other cities who have been protesting the shortages of food, water and electricity in other cities from getting to the capital.

“Why restrict the right to free transit?” the cardinal asked.

The Maduro regime also blocked the highway in February 2019 to prevent humanitarian aid from entering the country from Colombia.

Guaidó charged April 24 on Twitter that “a dictatorship of corrupt and incapable people has brought us to a crisis where farmers are losing their crops while families are starving to death in the barrios. They turned the richest country in the region into a hell. They’ll leave here, the sacrifice has been enough already.”

As signs of hope, Urosa pointed to ongoing work of Caritas Venezuela and the creative ways the clergy has reached out to the faithful through social media. “Our message is one of encouragement, trust in God, solidarity and hope in this dark hour,” he said.

 Catholics “have an unshakeable faith in God who is love,” who had died and risen and “has shown us the merciful face of God.” “We’ll come out of this,” the archbishop said, “the suffering we are experiencing has united us closer to God and opens to us the gates of heaven.”

The archbishop encouraged Venezuelans to always stand in solidarity with each other and “to be the face of God to those in need. God is love and is with us. Let us join ourselves to him and the Blessed Virgin Mary, Mother of Mercy in this painful hour.”

 

A version of this story was first published by ACI Prensa, CNA's Spanish-language news partner. It has been adapted by CNA.

Elaine Barry, associate professor of human development and family studies at Penn State Fayette, the Eberly Campus, and Janet Spearly, director of academic advising in the Smeal College of Business, have been selected to receive the 2020 Penn State Excellence in Advising Award.

The provisional schedule for the June 2021 finals has been released, with co-hosts Hungary and Slovenia in action on the opening day.

Political crises and violent protests rocked a number of countries in August, including Guatemala, Nepal, Lebanon and Iraq, where popular unrest threatens to topple the government and overturn the post-2003 political order. Deadly conflict worsened in Yemen, Afghanistan and Kashmir, while violence increased in Burundi following President Nkurunziza’s successful run for a third term, and instability remained the norm in the Central African Republic where UN peacekeeping efforts faced a series of setbacks. A border crisis also prompted a dangerous spike in tensions between Colombia and Venezuela. On a positive note, August saw a peace agreement in South Sudan, strengthened prospects for political and constitutional reform in Sri Lanka, and an important political agreement ahead of October elections in Guinea.

Political crises and violent protests rocked a number of countries in August, including Guatemala, Nepal, Lebanon and Iraq, where popular unrest threatens to topple the government and overturn the post-2003 political order. Deadly conflict worsened in Yemen, Afghanistan and Kashmir, while violence increased in Burundi following President Nkurunziza’s successful run for a third term, and instability remained the norm in the Central African Republic where UN peacekeeping efforts faced a series of setbacks. A border crisis also prompted a dangerous spike in tensions between Colombia and Venezuela. On a positive note, August saw a peace agreement in South Sudan, strengthened prospects for political and constitutional reform in Sri Lanka, and an important political agreement ahead of October elections in Guinea.

Following UN Special Representative for Libya Bernardino León’s announcement of a new Government of National Accord, Joost Hiltermann, Crisis Group’s Middle East and North Africa Program Director, had the following reaction.

The International Crisis Group congratulates the members of the Tunisian National Dialogue Quartet as this year’s recipient of the Nobel Peace Prize. It is an apt recognition of its achievement in allowing the spirit of inclusion and compromise to triumph over the polarisation and violence that has been all too prevalent in the region, and of the central role civil society can play at moments of crisis.

As armed conflicts in Afghanistan, Iraq, Nigeria, South Sudan, Syria, Yemen, and elsewhere continued to inflict much suffering and instability around the world, the heads of the UN and International Committee of the Red Cross issued an unprecedented joint warning about the impact of today’s conflicts on civilians and called on states to redouble their efforts to find sustainable solutions to conflicts. Welcoming the call to action, Jean-Marie Guéhenno, President & CEO of the International Crisis Group, said: “It is imperative that the world do much more to respond to early warning signs and prevent wars breaking out in the first place”.

November saw further military escalation and setbacks in Syria, particularly after Turkey shot down a Russian warplane it claimed had violated its airspace. Meanwhile, several countries faced extremist attacks claimed by the Islamic State (IS), including in Lebanon, France and Bangladesh. Violence also rose in Turkey between the state and Kurdish insurgents. In Venezuela, political tensions and violence increased ahead of parliamentary elections scheduled for 6 December and could worsen, while both Nepal and Kosovo faced deepening political crises. In a positive step forward, Burkina Faso and Myanmar experienced peaceful and openly-contested elections last month.

The month saw an intensification of deadly violence in Burundi’s capital, Bujumbura, with over 80 people killed following clashes with security forces. The African Union Peace and Security Council (AU PSC) made a welcome statement of intent to deploy forces to halt the slide toward civil war and mass atrocities. In Afghanistan, fighting raged between government and Taliban forces, particularly in Helmand province, while in Djibouti, Ethiopia and Niger, political tensions heightened. In a positive step forward, a peace deal was signed in Libya but uncertainties remain over the viability of the agreement. As stressed by Jean-Marie Guéhenno, President and CEO of the International Crisis Group, in today’s Ten Conflicts to Watch in 2016, it “should be seen as a beginning, not an end, to the peace process”.

The month saw an intensification of Yemen’s war, amid heightened regional rivalries between Saudi Arabia and Iran complicating prospects for peace. Political tensions increased in Haiti, Guinea-Bissau and Moldova, where protests over endemic corruption and a lack of confidence in the government could escalate. In Africa, Boko Haram’s deadly attacks increased in northern Cameroon, and Burkina Faso was hit by an unprecedented terror attack. On the nuclear front, in East Asia, North Korea’s announcement that it had carried out a successful hydrogen bomb test was roundly condemned, while nuclear-related sanctions on Iran were rolled back in accordance with the July 2015 deal.

The month saw conflict continue to rage in Turkey’s south east between Ankara and the Kurdistan Workers’ Party (PKK), looking likely to further escalate in March. Afghanistan and Somalia both saw armed insurgencies capture new territories. In Africa, political tensions rose in Chad, Mozambique and Zimbabwe, while in Venezuela, deadlock between the opposition-held parliament and government has brought the country closer to political and economic implosion. In Asia, North Korea’s announcement of a satellite launch in violation of UN Security Council resolutions prompted international condemnation and calls for tough new sanctions. On a positive note, the coming month brings the possibility of a final agreement to end Colombia’s decades-old insurgency.

The International Crisis Group is honoured to announce the creation of the Giustra Fellowship for Conflict Prevention, made possible by a generous gift of $1 million from Canadian businessman and philanthropic leader Frank Giustra through The Radcliffe Foundation. Mr. Giustra has been a long-time advocate for Crisis Group, providing transformational financial support since joining its Board of Trustees in 2005.

The month saw violent extremist movements, including the Islamic State (IS) and al-Qaeda-linked groups, carry out major deadly attacks in Turkey, Pakistan, Côte d’Ivoire, Tunisia and Belgium. In Libya, the arrival of Prime Minister Serraj in Tripoli despite warnings from multiple factions could lead to further destabilisation. Meanwhile in Central Africa, political violence rose in Burundi and could break out in Chad around the 10 April presidential election. Yemen, South Sudan and even Syria saw progress, of varying degrees, toward peace talks or implementation of agreements, and in Colombia the start of talks between the state and the National Liberation Army (ELN) could lead to the end of the 52-year-old conflict.

The month saw fighting escalate again in Syria and Afghanistan, and erupt in Nagorno-Karabakh between Armenian-backed separatists and Azerbaijani forces. In Bangladesh, election violence and killings by extremist groups showed how new heights of government-opposition rivalry and state repression have benefitted violent political party wings and extremist groups alike. Political tensions intensified in Iraq and Macedonia, and security forces severely supressed opposition protests in the Republic of Congo and Gambia. On a positive note, new governments were formed in the Central African Republic and South Sudan to consolidate peace gains, and talks to end Yemen’s one-year-old civil war got underway, albeit later than planned.

The month saw Venezuela’s political, economic and humanitarian crisis worsen amid heightened tensions between the government and opposition, a situation which could lead to state collapse and regional destabilisation. Another major setback in electing a new president in Haiti prompted fears of further civil unrest. In West Africa, deadly violence in central Mali and south-east Nigeria spiked, while a power struggle in Guinea-Bissau led to a dangerous standoff. In Libya, factions for and against the fledgling Government of National Accord (GNA) advanced on Sirte to expel the Islamic State (IS), risking clashes over oil facilities, while Turkey saw heightened political polarisation and an increase in violence in Kurdish areas. Ongoing peace talks, despite slow progress and ongoing violence, remain the best chance to end major combat in Yemen.

The month saw Venezuela’s political, economic and humanitarian crisis worsen amid heightened tensions between the government and opposition, a situation which could lead to state collapse and regional destabilisation. Another major setback in electing a new president in Haiti prompted fears of further civil unrest. In West Africa, deadly violence in central Mali and south-east Nigeria spiked, while a power struggle in Guinea-Bissau led to a dangerous standoff. In Libya, factions for and against the fledgling Government of National Accord (GNA) advanced on Sirte to expel the Islamic State (IS), risking clashes over oil facilities, while Turkey saw heightened political polarisation and an increase in violence in Kurdish areas. Ongoing peace talks, despite slow progress and ongoing violence, remain the best chance to end major combat in Yemen.

• Football stars show how to practise skills without breaking safety rules – or windows!
• Federation raises funds for coronavirus and earthquake aid

• English FA launches ‘Football’s staying home’ campaign
• Captains lead Premier League teams into #PlayersTogether partnership with National Health Service Charities Together
• English Football League uses relief fund to help clubs facing cashflow problems
• Numerous club initiatives to help local communities

• Bundesliga UEFA Champions League participants show solidarity

• Free pizza for health workers
• Men’s and women’s national teams appear in StaySafeHome video
• Teaming up with mental health charities to help people cope with self-isolation