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Post-droughts, Himachal wakes up to combat climate change dangers

Two droughts wiping out 50 per cent of the rabi crop, the apple produce reduced to half of its usual quantity, the unusual rise in temperature...




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MP''s soybean, wheat yield to decline in two decades: Study

The state was chosen for the India-UK study as it is most vulnerable to adverse impacts of climate change




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In season of ups and downs, kinnow clicks when sour

And farmers still managed good prices in the beginning because of better marketing, though these eventually did drop in the glut.




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Variety of offers, one clicks

Punjab Agriculture University launches two new varieties each of paddy and basmati; most farmers opt for the paddy option that promises the higher yield




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Climate study for better agriculture

Temperatures rising by the year and rainfall erratic, Punjab sets up centre for research on how its changing climate has been affecting its crops, and how to protect them




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Retail unsecured loans, cross-selling may decline post moratorium

Lenders say the larger challenge is to communicate to borrowers the difference between moratorium and waiver




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Mumbai's corona cases climb to 11,967; toll 462




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Theatre games : a new approach to drama training / Clive Barker

Barker, Clive, 1931-




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Highly Z-selective synthesis of 1,3-oxathiol-2-ylidenes and 4-methylene-oxazolidine-2-thiones via atom-specific 5-exo-dig cyclization of propargyl alcohol with isothiocyanate

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00083C, Paper
S. Antony Savarimuthu, D. G. Leo Prakash, S. Augustine Thomas, Thirumanavelan Gandhi, Mrinal K. Bera
The Z-selectivity observed in imine and alkene motifs after 5-exo-dig cyclization of propargyl alcohol and isothiocyanate is rare in the literature and this selectivity can be attributed to electronic and steric factors of the imine and alkene motif respectively.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Selenium-promoted electrophilic cyclization of arylpropiolamides: synthesis of 3-organoselenyl spiro[4,5]trienones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00609B, Paper
Ana Maria S. Recchi, Pedro H. P. Rosa, Davi F. Back, Gilson Zeni
A synthetic approach to regioselective synthesis of 3-organochalcogenyl spiro[4,5]trienones and 3-organochalcogenyl[4,5]triene-2,6-diones is described through the reaction of arylpropiolamides with an electrophilic chalcogen source.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Diversity oriented multi-component reaction (DOS–MCR) approach to access natural product analogues: regio- and chemo-selective synthesis of polyheterocyclic scaffolds via one-pot cascade reactions

Org. Biomol. Chem., 2020, 18,3082-3092
DOI: 10.1039/D0OB00368A, Paper
Lakshmanan Palanivel, Vasuki Gnanasambandam
Skeletally diverse and complex polyheterocyclic hybrid scaffolds have been accessed via one-pot three-component reaction by exploiting the build/couple/pair strategy of diversity oriented synthesis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination

Org. Biomol. Chem., 2020, 18,3012-3016
DOI: 10.1039/D0OB00155D, Communication
Alexander S. Henderson, John F. Bower, M. Carmen Galan
The practical synthesis of pseudo-enantiomeric carbohydrate-based NHC–Rh complexes bearing C1 or C3 sterically differentiated positions is reported. We show that steric bulk at either C1 or C3 leads to enantiotopic discrimination in the hydrosilylation of acetophenone.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Photocatalytic xanthate-based radical addition/cyclization reaction sequence toward 2-biphenyl isocyanides: synthesis of 6-alkylated phenanthridines

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00136H, Communication
Pedro López-Mendoza, Luis D. Miranda
A photocatalytic xanthate-based radical addition/cyclization reaction cascade toward 2-biphenylisocyanides is described as a practical and modular approach to 6-alkylated phenanthridines.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Study on the ArI-catalyzed intramolecular oxy-cyclization of 2-alkenylbenzamides to benzoiminolactones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00612B, Communication
Huixia Liu, Xiaojun Deng, Xie Huang, Nan Ji, Wei He
A metal-free synthetic method toward the preparation of benzoiminolactones through oxy-cyclization of 2-alkenylbenzamides mediated by a catalyst/oxidant (ArI/mCPBA) system was developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Visible light promoted continuous flow photocyclization of 1,2-diketones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00532K, Paper
Francesco Secci, Stefania Porcu, Alberto Luridiana, Angelo Frongia, Pier Carlo Ricci
A continuous flow Norrish–Yang photocyclization of 1,2-diketones has been developed and applied to the synthesis of functionalized 2-hydroxycyclobutanones, under blue light irradiation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A laccase-catalysed tyrosine click reaction

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00650E, Communication
Shinichi Sato, Keita Nakane, Hiroyuki Nakamura
The tyrosine click reaction of peptides/proteins with the tyrosine modification reagent, N-methyl luminol, was catalysed by a laccase in the presence of molecular oxygen (O2) at 37 °C.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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A base-promoted tandem approach to bicyclic 8-membered ring ketones

Org. Biomol. Chem., 2020, 18,3249-3253
DOI: 10.1039/D0OB00618A, Communication
Emerson E. F. dos Santos, Gabriela F. P. de Souza, Deborah A. Simoni, Airton G. Salles
A base-promoted tandem route toward unprecedented bicyclic furan/8-membered ring ketones is reported.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chemo- and regioselective click reactions through nickel-catalyzed azide–alkyne cycloaddition

Org. Biomol. Chem., 2020, 18,3374-3381
DOI: 10.1039/D0OB00579G, Paper
Woo Gyum Kim, Seung-yeol Baek, Seo Yeong Jeong, Dongsik Nam, Ji Hwan Jeon, Wonyoung Choe, Mu-Hyun Baik, Sung You Hong
Nickel-catalyzed [3 + 2] cycloaddition reactions of unsymmetrical alkynes and organic azides afford substituted 1,2,3-triazoles with high levels of chemo- and regioselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chiral bifunctional sulfide-catalyzed asymmetric bromoaminocyclizations

Org. Biomol. Chem., 2020, 18,3367-3373
DOI: 10.1039/D0OB00459F, Paper
Takumi Nakamura, Ken Okuno, Kazuma Kaneko, Masahiro Yamanaka, Seiji Shirakawa
A chiral bifunctional sulfide catalyst bearing a urea moiety promotes the enantioselective bromoaminocyclization of 2-allylanilines to produce optically active 2-substituted indolines.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Gold(III)-catalyzed azide-yne cyclization/O–H insertion cascade reaction for the expeditious construction of 3-alkoxy-4-quinolinone frameworks

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00745E, Paper
Jingjing Huang, Han Su, Ming Bao, Lihua Qiu, Yuanqing Zhang, Xinfang Xu
A gold-catalyzed cascade reaction has been developed, and it provides an expeditious access to 3-alkoxy-4-quinolines and applications in alkaloid synthesis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Efficient synthesis of a galectin inhibitor clinical candidate (TD139) using a Payne rearrangement/azidation reaction cascade

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00910E, Paper
Jacob St-Gelais, Vincent Denavit, Denis Giguère
Selective galectin inhibitors are valuable research tools and could also be used as drug candidates. In that context, TD139, a thiodigalactoside galectin-3 inhibitor, is currently being evaluated clinically for the...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Climbing Everest, I've proved a tribal girl can do something: Malavath Poorna

At just 13 years, Malavath Poorna from Telangana has become the youngest female climber in the world to scale Mount Everest. Speaking with Rohit E David, Poorna discussed how she has emerged from a family of agricultural labourers to become a mountaineer, the difficulties she faced while navigating Mount Everest, the one thought that kept her going — and how she wants to climb many more mountains now.




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Plea on metro card-address proof linking declined




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Healthy Aging: A Complete Guide to Clinical Management / editor, Patrick P. Coll

Online Resource




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Exploring sources of variability related to the clinical translation of regenerative engineering products: proceedings of a workshop / Meredith Hackmann, Theresa Wizemann, and Sarah H. Beachy, rapporteurs ; Forum on Regenerative Medicine, Board on Health

Online Resource




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Gaia, psyche and deep ecology: navigating climate change in the anthropocene / Andrew Fellows

Dewey Library - QH331.F35 2019




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Basic & clinical biostatistics.

Dewey Library - QH323.5.W45 2020




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[ASAP] Particulate Matter Toxicity Is Nrf2 and Mitochondria Dependent: The Roles of Metals and Polycyclic Aromatic Hydrocarbons

Chemical Research in Toxicology
DOI: 10.1021/acs.chemrestox.0c00007




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WIRED Live - Bill Gates & President Bill Clinton: Technology and the Value of Connectivity-Exclusive Interview

From medical vaccines to financial services to educational resources, connectivity is key. Bill Gates and President Bill Clinton explain the positive impact of being plugged in on a global scale. For more from Bill Gates and President Clinton, check out the December 2013 issue of WIRED.




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WIRED Live - Bill Gates & President Bill Clinton: The Global Economy and the End of American Exceptionalism-Exclusive Interview

With American exceptionalism waning, is the U.S. destined to be left in the dust? Bill Gates and President Bill Clinton talk about the significance of building a future of shared success and responsibility in order to create a thriving global economy. For more from Bill Gates and President Clinton, check out the December 2013 issue of WIRED.




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WIRED Live - Bill Gates & President Bill Clinton: Changing the World Through Philanthropy-Exclusive Interview

Bill Gates and President Bill Clinton have managed to transition from Microsoft co-founder and former U.S. commander-in-chief to hands-on philanthropists. With a passion for charity and aid work, the two describe their health- and education-focused initiatives, and explain why their statuses don’t mean squat when they’re helping out in developing nations. For more from Bill Gates and President Clinton, check out the December 2013 issue of WIRED.




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WIRED Live - Bill Gates & President Bill Clinton: Looking Forward and Maintaining Optimism-Exclusive Interview

Passion and optimism often go hand-in-hand, which couldn’t be truer for Bill Gates and President Bill Clinton when it comes to their outlook on the future. The two share their thoughts on the rapid pace and excitement of today’s innovations, and how humanity’s balance between conflict and cooperation will continue to fuel economic opportunity for years to come. For more from Bill Gates and President Clinton, check out the December 2013 issue of WIRED.




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Angry Nerd - Why Clint Eastwood’s “Jersey Boys” is Destined to Crash & Burn on the Big Screen

Musicals. They’re great. But jukebox musicals? That’s an entirely different—and often terrible—story. Even with Clint Eastwood behind the camera of the new stage-to-film rendition of Jersey Boys, there’s only so much Dirty Harry can do for the destined-to-flop silver screen adaptation.




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How to Make a Giant Creature - How to Make Monster Sounds with the Click of a Button

Wonder how Bodock the Giant Creature and his alien sidekick got their voices? In this episode, we take a trip to Anarchy Post to see how the creature's voice came to life with the help of voice actors and Dehumaniser—a real-time vocal processor for monster sound FX.




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Angry Nerd - Horror Movie Cliches that Deserve to be Slaughtered

Angry Nerd is sick of the latest crop of cliché killer movies. Do we really need Michael Bay bringing another Hasbro product to life with “Ouija"? Who asked for the new wannabe “Blair Witch Project” called “Exists”? Angry Nerd explains why the only frightening thing this Halloween is the surplus of crappy horror flicks.




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Angry Nerd - Clicking Dislike on the Cyber-Horror Film "Unfriended"

The new horror movie “Unfriended” uses a screen-capture format to shape the film’s narrative. But guess what? Using Facebook messages, Skype calls, and Gchats to tell a story isn’t innovative, it’s LAZY! Angry Nerd explains why the cyber-horror flick deserves an IRL “dislike."




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"Planetary" Exclusive Clip

In this exclusive clip from the new documentary "Planetary," we learn how space travel has affected human beings on a greater scale, allowing us to view the world in which we live, with a completely new perspective.




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Facebook Rolls Out 360 Video with Star Wars Clip

You’ll now be able to see immersive videos in your Facebook feed. As part of the rollout, you can speed across the Jakku desert of the upcoming Star Wars: The Force Awakens in a 360 video created by Disney exclusively for Facebook.




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Get Ready for the Supermoon Eclipse

Polish up that telescope! This weekend night owls will enjoy the sight of a total lunar eclipse which will just happen to occur during a supermoon, when the moon passes closest to earth's surface.




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You'll Never Believe How We Got You to Click on This Video

Clickbait isn't art, it's a science. Click and find out how it works.




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King Tides Show Us How Climate Change Will Threaten Coastal Cities

Seawall-topping king tides occur when extra-high tides line up with other meteorological anomalies. In the past they were a novelty or a nuisance. Now they hint at the new normal, when sea level rise will render current coastlines obsolete.




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An AR Rock Climbing Game

Jon Cheng and the Brooklyn Boulder Gym are working together on a real life video game for rock climbers.




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Exclusive Clip: ‘The BFG'

Not-so-friendly giant Fleshlumpeater visits the BFG in this exclusive clip from Steven Spielberg’s new movie.




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Climb Inside Uber's Self-Driving Car—Its Next Big Disruption

The ride-sharing giant is in Pittsburgh for its latest big move: the country’s first autonomous taxi service. Select Uber users can now ride in self-driving cars, with humans at the wheel for an emergency.




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NASA Creates Robots That Can Climb Walls

We take a look at some of the new robotic technology being developed at JPL's Robotics Lab, including robots that use "gecko" technology to grip walls and climb 90 degree surfaces.




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John Kerry on How the Paris Climate Agreement Could Help Fight Terrorism

US Secretary of State John Kerry discusses the ways that recently signed UN climate agreement will spur innovations in renewable energy across the globe, including terror hotspots.




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How to Fight the Bad Logic of the Internet | Argument Clinic

There's a lot of bad logic out there. WIRED's Jason Tanz explains how to spot and fight the dumbest arguments online.




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Planet Earth II : Exclusive Clip From Episode 3 ‘Jungles’

An exclusive clip from the upcoming BBC America film Planet Earth II.




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Flight Lab - Climb Aboard a Boeing 747 That NASA Turned Into the World's Biggest Flying Telescope

To get the best space observations possible, NASA scientists fly around the world in a highly modified 747 carrying a giant telescope.




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How Climate Change Is Already Affecting Earth

Though the planet has only warmed by one-degree Celsius since the Industrial Revolution, climate change's effect on earth has been anything but subtle. Here are some of the most astonishing developments over the past few years.