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The educational and subsidiary provisions of the Birmingham Royal School of Medicine and Surgery set forth in a letter to the Rev. Dr. Samuel Wilson Warneford ... : the whole being intended to shew the importance and practicability of applying the means a

Oxford : printed by W. Baxter, 1843.




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Ein eigentumlich verlaufender Fall von Phthisis Pulmonum : Inaugural-Dissertation ... / vorgelegt von Carlos Kraemer.

Tubingen : H. Laupp, Jr, 1889.




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An elementary treatise on the function of vision and its anomalies / by Dr. Giraud-Teulon ; translated from the second French edition by Lloyd Owen.

London : Bailliere, Tindall, & Cox, 1880.




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Elements of medical jurisprudence; or, A succinct and compendious description of such tokens in the human body as are requisite to determine the judgment of a coroner, and courts of law, in cases of divorce, rape, murder, &c : To which are added, Dire

London : printed for J. Callow, 1814.




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The elements of mind : being an examination into the nature of the first division of the elementary substances of life / by H. Jamyn Brooks.

London : Longmans, Green, 1902.




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Elements of pharmacology / by Oswald Schmiedeberg ; translated under the author's supervision by Thomas Dixson.

Edinburgh : Young J. Pentland, 1887.




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Florida Governor Signs Divisive Bill Allowing for Armed Teachers

Florida's governor signed a bill that will allow schools to arm classroom teachers, part of a longer list of school safety changes made after a school shooting in Parkland, Fla., last year.




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W.Va. Partnership Supports Grandparents in Raising School-Age Children

Nearly 45 percent of children in rural McDowell County, West Virginia do not live with their parents and many are being raised by grandparents.




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A rich man and a woman who has visited him for tea gossip about an impoverished gentleman's daughter who is present in his house as a governess: the visitor looks at the governess with a supercilious expression. Engraving by R. Hatfield, 1842, after R

London (No. 4, Hanover Street) : Published ... for the proprietor by T.G. March ; [London] (Threadneedle Street) : Sold also by F. G. Moon ; [London] (Strand) : [Sold also by] Ackermann & Co., April 10, 1842 ([London?] : Printed by R. Lloyd)




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Oedipus at Colonus: the blind Oedipus, attended by Antigone, is visited by Ismene and by Polynices. Engraving by A.A. Morel after A. Giroust.




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A man visits a country cottage and pays a young woman; local children protect a pet lamb. Lithograph, 18--.

Berlin (Louisen-Str. 53) : Published by F. Silber, [between 1800 and 1899]




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The personification of the art of painting, supported by Cardinal Girolamo Buonvisi, arrives on a triumphal car at Mount Helicon where she is greeted by the muses. Etching by P. Testa.

[Rome?]




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The second feast of Esther: Haman bows before Esther, seeking her pardon for his plan to kill her and all other Jews; King Ahasuerus returns to the room in rage and misinterprets his action. Engraving, 17--.




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In Flint, Schools Overwhelmed by Special Ed. Needs in Aftermath of Lead Crisis

The children exposed to high levels of lead-laced drinking water from Michigan's Flint River are entering schools now and the school system is straining to meet their special education needs.




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Billionaire Elon Musk Donates $480K to Help Flint Schools Deal With Water Crisis

The donation comes as Flint city and school leaders continue to grapple with the fallout from a contaminated-water crisis that began in 2015. The filtration systems, which will be installed by January, should allow students to once again district students and staff to drink from and fill up water bo




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Penguins may face ‘tough decisions’ with goalies thanks to salary cap crunch

Could they lose one or more of Murray, Jarry, and DeSmith?




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Revisiting biggest NHL trades from the 2019 offseason

Kerfoot discussing his first Maple Leafs season spurred a larger discussion.




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Report on Harrogate visit / by L. S. P. Davidson.

England : Harrogate Corporation, Wells and Baths Department, 1945.




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The nature and treatment of nonopiate abuse : a review of the literature. Volume 2 / Wynne Associates for Division of Research, National Institute on Drug Abuse, Alcohol, Drug Abuse and Mental Health Administration, Department of Health, Education and Wel

Washington, D.C. : Wynne Associates, 1974.




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Evaluation of treatment programs for abusers of nonopiate drugs : problems and approaches. Volume 3 / Wynne Associates for Division of Research, National Institute on Drug Abuse, Alcohol, Drug Abuse and Mental Health Administration, Department of Health,

Washington, D.C. : Wynne Associates, [1974]




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Policy and guidelines for the provision of needle and syringe exchange services to young people / Tom Aldridge and Andrew Preston.

[Dorchester] : Dorset Community NHS Trust, 1997.




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Sparse equisigned PCA: Algorithms and performance bounds in the noisy rank-1 setting

Arvind Prasadan, Raj Rao Nadakuditi, Debashis Paul.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 345--385.

Abstract:
Singular value decomposition (SVD) based principal component analysis (PCA) breaks down in the high-dimensional and limited sample size regime below a certain critical eigen-SNR that depends on the dimensionality of the system and the number of samples. Below this critical eigen-SNR, the estimates returned by the SVD are asymptotically uncorrelated with the latent principal components. We consider a setting where the left singular vector of the underlying rank one signal matrix is assumed to be sparse and the right singular vector is assumed to be equisigned, that is, having either only nonnegative or only nonpositive entries. We consider six different algorithms for estimating the sparse principal component based on different statistical criteria and prove that by exploiting sparsity, we recover consistent estimates in the low eigen-SNR regime where the SVD fails. Our analysis reveals conditions under which a coordinate selection scheme based on a sum-type decision statistic outperforms schemes that utilize the $ell _{1}$ and $ell _{2}$ norm-based statistics. We derive lower bounds on the size of detectable coordinates of the principal left singular vector and utilize these lower bounds to derive lower bounds on the worst-case risk. Finally, we verify our findings with numerical simulations and a illustrate the performance with a video data where the interest is in identifying objects.




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Exact recovery in block spin Ising models at the critical line

Matthias Löwe, Kristina Schubert.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1796--1815.

Abstract:
We show how to exactly reconstruct the block structure at the critical line in the so-called Ising block model. This model was recently re-introduced by Berthet, Rigollet and Srivastava in [2]. There the authors show how to exactly reconstruct blocks away from the critical line and they give an upper and a lower bound on the number of observations one needs; thereby they establish a minimax optimal rate (up to constants). Our technique relies on a combination of their methods with fluctuation results obtained in [20]. The latter are extended to the full critical regime. We find that the number of necessary observations depends on whether the interaction parameter between two blocks is positive or negative: In the first case, there are about $Nlog N$ observations required to exactly recover the block structure, while in the latter case $sqrt{N}log N$ observations suffice.




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GluonCV and GluonNLP: Deep Learning in Computer Vision and Natural Language Processing

We present GluonCV and GluonNLP, the deep learning toolkits for computer vision and natural language processing based on Apache MXNet (incubating). These toolkits provide state-of-the-art pre-trained models, training scripts, and training logs, to facilitate rapid prototyping and promote reproducible research. We also provide modular APIs with flexible building blocks to enable efficient customization. Leveraging the MXNet ecosystem, the deep learning models in GluonCV and GluonNLP can be deployed onto a variety of platforms with different programming languages. The Apache 2.0 license has been adopted by GluonCV and GluonNLP to allow for software distribution, modification, and usage.




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Lower Bounds for Testing Graphical Models: Colorings and Antiferromagnetic Ising Models

We study the identity testing problem in the context of spin systems or undirected graphical models, where it takes the following form: given the parameter specification of the model $M$ and a sampling oracle for the distribution $mu_{M^*}$ of an unknown model $M^*$, can we efficiently determine if the two models $M$ and $M^*$ are the same? We consider identity testing for both soft-constraint and hard-constraint systems. In particular, we prove hardness results in two prototypical cases, the Ising model and proper colorings, and explore whether identity testing is any easier than structure learning. For the ferromagnetic (attractive) Ising model, Daskalakis et al. (2018) presented a polynomial-time algorithm for identity testing. We prove hardness results in the antiferromagnetic (repulsive) setting in the same regime of parameters where structure learning is known to require a super-polynomial number of samples. Specifically, for $n$-vertex graphs of maximum degree $d$, we prove that if $|eta| d = omega(log{n})$ (where $eta$ is the inverse temperature parameter), then there is no polynomial running time identity testing algorithm unless $RP=NP$. In the hard-constraint setting, we present hardness results for identity testing for proper colorings. Our results are based on the presumed hardness of #BIS, the problem of (approximately) counting independent sets in bipartite graphs.




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The weight function in the subtree kernel is decisive

Tree data are ubiquitous because they model a large variety of situations, e.g., the architecture of plants, the secondary structure of RNA, or the hierarchy of XML files. Nevertheless, the analysis of these non-Euclidean data is difficult per se. In this paper, we focus on the subtree kernel that is a convolution kernel for tree data introduced by Vishwanathan and Smola in the early 2000's. More precisely, we investigate the influence of the weight function from a theoretical perspective and in real data applications. We establish on a 2-classes stochastic model that the performance of the subtree kernel is improved when the weight of leaves vanishes, which motivates the definition of a new weight function, learned from the data and not fixed by the user as usually done. To this end, we define a unified framework for computing the subtree kernel from ordered or unordered trees, that is particularly suitable for tuning parameters. We show through eight real data classification problems the great efficiency of our approach, in particular for small data sets, which also states the high importance of the weight function. Finally, a visualization tool of the significant features is derived.




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Identifying the consequences of dynamic treatment strategies: A decision-theoretic overview

A. Philip Dawid, Vanessa Didelez

Source: Statist. Surv., Volume 4, 184--231.

Abstract:
We consider the problem of learning about and comparing the consequences of dynamic treatment strategies on the basis of observational data. We formulate this within a probabilistic decision-theoretic framework. Our approach is compared with related work by Robins and others: in particular, we show how Robins’s ‘ G -computation’ algorithm arises naturally from this decision-theoretic perspective. Careful attention is paid to the mathematical and substantive conditions required to justify the use of this formula. These conditions revolve around a property we term stability , which relates the probabilistic behaviours of observational and interventional regimes. We show how an assumption of ‘sequential randomization’ (or ‘no unmeasured confounders’), or an alternative assumption of ‘sequential irrelevance’, can be used to infer stability. Probabilistic influence diagrams are used to simplify manipulations, and their power and limitations are discussed. We compare our approach with alternative formulations based on causal DAGs or potential response models. We aim to show that formulating the problem of assessing dynamic treatment strategies as a problem of decision analysis brings clarity, simplicity and generality.

References:
Arjas, E. and Parner, J. (2004). Causal reasoning from longitudinal data. Scandinavian Journal of Statistics 31 171–187.

Arjas, E. and Saarela, O. (2010). Optimal dynamic regimes: Presenting a case for predictive inference. The International Journal of Biostatistics 6. http://tinyurl.com/33dfssf

Cowell, R. G., Dawid, A. P., Lauritzen, S. L. and Spiegelhalter, D. J. (1999). Probabilistic Networks and Expert Systems. Springer, New York.

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Dawid, A. P. (1998). Conditional independence. In Encyclopedia of Statistical Science ({U}pdate Volume 2) ( S. Kotz, C. B. Read and D. L. Banks, eds.) 146–155. Wiley-Interscience, New York.

Dawid, A. P. (2000). Causal inference without counterfactuals (with Discussion). Journal of the American Statistical Association 95 407–448.

Dawid, A. P. (2001). Separoids: A mathematical framework for conditional independence and irrelevance. Annals of Mathematics and Artificial Intelligence 32 335–372.

Dawid, A. P. (2002). Influence diagrams for causal modelling and inference. International Statistical Review 70 161–189. Corrigenda, ibid ., 437.

Dawid, A. P. (2003). Causal inference using influence diagrams: The problem of partial compliance (with Discussion). In Highly Structured Stochastic Systems ( P. J. Green, N. L. Hjort and S. Richardson, eds.) 45–81. Oxford University Press.

Dawid, A. P. (2010). Beware of the DAG! In Proceedings of the NIPS 2008 Workshop on Causality. Journal of Machine Learning Research Workshop and Conference Proceedings ( D. Janzing, I. Guyon and B. Schölkopf, eds.) 6 59–86. http://tinyurl.com/33va7tm

Dawid, A. P. and Didelez, V. (2008). Identifying optimal sequential decisions. In Proceedings of the Twenty-Fourth Annual Conference on Uncertainty in Artificial Intelligence (UAI-08) ( D. McAllester and A. Nicholson, eds.). 113-120. AUAI Press, Corvallis, Oregon. http://tinyurl.com/3899qpp

Dechter, R. (2003). Constraint Processing. Morgan Kaufmann Publishers.

Didelez, V., Dawid, A. P. and Geneletti, S. G. (2006). Direct and indirect effects of sequential treatments. In Proceedings of the Twenty-Second Annual Conference on Uncertainty in Artificial Intelligence (UAI-06) ( R. Dechter and T. Richardson, eds.). 138-146. AUAI Press, Arlington, Virginia. http://tinyurl.com/32w3f4e

Didelez, V., Kreiner, S. and Keiding, N. (2010). Graphical models for inference under outcome dependent sampling. Statistical Science (to appear).

Didelez, V. and Sheehan, N. S. (2007). Mendelian randomisation: Why epidemiology needs a formal language for causality. In Causality and Probability in the Sciences, ( F. Russo and J. Williamson, eds.). Texts in Philosophy Series 5 263–292. College Publications, London.

Eichler, M. and Didelez, V. (2010). Granger-causality and the effect of interventions in time series. Lifetime Data Analysis 16 3–32.

Ferguson, T. S. (1967). Mathematical Statistics: A Decision Theoretic Approach. Academic Press, New York, London.

Geneletti, S. G. (2007). Identifying direct and indirect effects in a non–counterfactual framework. Journal of the Royal Statistical Society: Series B 69 199–215.

Geneletti, S. G. and Dawid, A. P. (2010). Defining and identifying the effect of treatment on the treated. In Causality in the Sciences ( P. M. Illari, F. Russo and J. Williamson, eds.) Oxford University Press (to appear).

Gill, R. D. and Robins, J. M. (2001). Causal inference for complex longitudinal data: The continuous case. Annals of Statistics 29 1785–1811.

Guo, H. and Dawid, A. P. (2010). Sufficient covariates and linear propensity analysis. In Proceedings of the Thirteenth International Workshop on Artificial Intelligence and Statistics, (AISTATS) 2010, Chia Laguna, Sardinia, Italy, May 13-15, 2010. Journal of Machine Learning Research Workshop and Conference Proceedings ( Y. W. Teh and D. M. Titterington, eds.) 9 281–288. http://tinyurl.com/33lmuj7

Henderson, R., Ansel, P. and Alshibani, D. (2010). Regret-regression for optimal dynamic treatment regimes. Biometrics (to appear). doi:10.1111/j.1541-0420.2009.01368.x

Hernán, M. A. and Taubman, S. L. (2008). Does obesity shorten life? The importance of well defined interventions to answer causal questions. International Journal of Obesity 32 S8–S14.

Holland, P. W. (1986). Statistics and causal inference (with Discussion). Journal of the American Statistical Association 81 945–970.

Huang, Y. and Valtorta, M. (2006). Identifiability in causal Bayesian networks: A sound and complete algorithm. In AAAI’06: Proceedings of the 21st National Conference on Artificial Intelligence 1149–1154. AAAI Press.

Kang, J. D. Y. and Schafer, J. L. (2007). Demystifying double robustness: A comparison of alternative strategies for estimating a population mean from incomplete data. Statistical Science 22 523–539.

Lauritzen, S. L., Dawid, A. P., Larsen, B. N. and Leimer, H. G. (1990). Independence properties of directed Markov fields. Networks 20 491–505.

Lok, J., Gill, R., van der Vaart, A. and Robins, J. (2004). Estimating the causal effect of a time-varying treatment on time-to-event using structural nested failure time models. Statistica Neerlandica 58 271–295.

Moodie, E. M., Richardson, T. S. and Stephens, D. A. (2007). Demystifying optimal dynamic treatment regimes. Biometrics 63 447–455.

Murphy, S. A. (2003). Optimal dynamic treatment regimes (with Discussion). Journal of the Royal Statistical Society, Series B 65 331-366.

Oliver, R. M. and Smith, J. Q., eds. (1990). Influence Diagrams, Belief Nets and Decision Analysis. John Wiley and Sons, Chichester, United Kingdom.

Pearl, J. (1995). Causal diagrams for empirical research (with Discussion). Biometrika 82 669-710.

Pearl, J. (2009). Causality: Models, Reasoning and Inference, Second ed. Cambridge University Press, Cambridge.

Pearl, J. and Paz, A. (1987). Graphoids: A graph-based logic for reasoning about relevance relations. In Advances in Artificial Intelligence ( D. Hogg and L. Steels, eds.) II 357–363. North-Holland, Amsterdam.

Pearl, J. and Robins, J. (1995). Probabilistic evaluation of sequential plans from causal models with hidden variables. In Proceedings of the 11th Conference on Uncertainty in Artificial Intelligence ( P. Besnard and S. Hanks, eds.) 444–453. Morgan Kaufmann Publishers, San Francisco.

Raiffa, H. (1968). Decision Analysis. Addison-Wesley, Reading, Massachusetts.

Robins, J. M. (1986). A new approach to causal inference in mortality studies with sustained exposure periods—Application to control of the healthy worker survivor effect. Mathematical Modelling 7 1393–1512.

Robins, J. M. (1987). Addendum to “A new approach to causal inference in mortality studies with sustained exposure periods—Application to control of the healthy worker survivor effect”. Computers & Mathematics with Applications 14 923–945.

Robins, J. M. (1989). The analysis of randomized and nonrandomized AIDS treatment trials using a new approach to causal inference in longitudinal studies. In Health Service Research Methodology: A Focus on AIDS ( L. Sechrest, H. Freeman and A. Mulley, eds.) 113–159. NCSHR, U.S. Public Health Service.

Robins, J. M. (1992). Estimation of the time-dependent accelerated failure time model in the presence of confounding factors. Biometrika 79 321–324.

Robins, J. M. (1997). Causal inference from complex longitudinal data. In Latent Variable Modeling and Applications to Causality, ( M. Berkane, ed.). Lecture Notes in Statistics 120 69–117. Springer-Verlag, New York.

Robins, J. M. (1998). Structural nested failure time models. In Survival Analysis, ( P. K. Andersen and N. Keiding, eds.). Encyclopedia of Biostatistics 6 4372–4389. John Wiley and Sons, Chichester, UK.

Robins, J. M. (2000). Robust estimation in sequentially ignorable missing data and causal inference models. In Proceedings of the American Statistical Association Section on Bayesian Statistical Science 1999 6–10.

Robins, J. M. (2004). Optimal structural nested models for optimal sequential decisions. In Proceedings of the Second Seattle Symposium on Biostatistics ( D. Y. Lin and P. Heagerty, eds.) 189–326. Springer, New York.

Robins, J. M., Greenland, S. and Hu, F. C. (1999). Estimation of the causal effect of a time-varying exposure on the marginal mean of a repeated binary outcome. Journal of the American Statistical Association 94 687–700.

Robins, J. M., Hernán, M. A. and Brumback, B. (2000). Marginal structural models and causal inference in epidemiology. Epidemiology 11 550–560.

Robins, J. M. and Wasserman, L. A. (1997). Estimation of effects of sequential treatments by reparameterizing directed acyclic graphs. In Proceedings of the 13th Annual Conference on Uncertainty in Artificial Intelligence ( D. Geiger and P. Shenoy, eds.) 409-420. Morgan Kaufmann Publishers, San Francisco. http://tinyurl.com/33ghsas

Rosthøj, S., Fullwood, C., Henderson, R. and Stewart, S. (2006). Estimation of optimal dynamic anticoagulation regimes from observational data: A regret-based approach. Statistics in Medicine 25 4197–4215.

Shpitser, I. and Pearl, J. (2006a). Identification of conditional interventional distributions. In Proceedings of the 22nd Annual Conference on Uncertainty in Artificial Intelligence (UAI-06) ( R. Dechter and T. Richardson, eds.). 437–444. AUAI Press, Corvallis, Oregon. http://tinyurl.com/2um8w47

Shpitser, I. and Pearl, J. (2006b). Identification of joint interventional distributions in recursive semi-Markovian causal models. In Proceedings of the Twenty-First National Conference on Artificial Intelligence 1219–1226. AAAI Press, Menlo Park, California.

Spirtes, P., Glymour, C. and Scheines, R. (2000). Causation, Prediction and Search, Second ed. Springer-Verlag, New York.

Sterne, J. A. C., May, M., Costagliola, D., de Wolf, F., Phillips, A. N., Harris, R., Funk, M. J., Geskus, R. B., Gill, J., Dabis, F., Miro, J. M., Justice, A. C., Ledergerber, B., Fatkenheuer, G., Hogg, R. S., D’Arminio-Monforte, A., Saag, M., Smith, C., Staszewski, S., Egger, M., Cole, S. R. and When To Start Consortium (2009). Timing of initiation of antiretroviral therapy in AIDS-Free HIV-1-infected patients: A collaborative analysis of 18 HIV cohort studies. Lancet 373 1352–1363.

Taubman, S. L., Robins, J. M., Mittleman, M. A. and Hernán, M. A. (2009). Intervening on risk factors for coronary heart disease: An application of the parametric g-formula. International Journal of Epidemiology 38 1599–1611.

Tian, J. (2008). Identifying dynamic sequential plans. In Proceedings of the Twenty-Fourth Annual Conference on Uncertainty in Artificial Intelligence (UAI-08) ( D. McAllester and A. Nicholson, eds.). 554–561. AUAI Press, Corvallis, Oregon. http://tinyurl.com/36ufx2h

Verma, T. and Pearl, J. (1990). Causal networks: Semantics and expressiveness. In Uncertainty in Artificial Intelligence 4 ( R. D. Shachter, T. S. Levitt, L. N. Kanal and J. F. Lemmer, eds.) 69–76. North-Holland, Amsterdam.




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Wilcoxon-Mann-Whitney or t-test? On assumptions for hypothesis tests and multiple interpretations of decision rules

Michael P. Fay, Michael A. Proschan

Source: Statist. Surv., Volume 4, 1--39.

Abstract:
In a mathematical approach to hypothesis tests, we start with a clearly defined set of hypotheses and choose the test with the best properties for those hypotheses. In practice, we often start with less precise hypotheses. For example, often a researcher wants to know which of two groups generally has the larger responses, and either a t-test or a Wilcoxon-Mann-Whitney (WMW) test could be acceptable. Although both t-tests and WMW tests are usually associated with quite different hypotheses, the decision rule and p-value from either test could be associated with many different sets of assumptions, which we call perspectives. It is useful to have many of the different perspectives to which a decision rule may be applied collected in one place, since each perspective allows a different interpretation of the associated p-value. Here we collect many such perspectives for the two-sample t-test, the WMW test and other related tests. We discuss validity and consistency under each perspective and discuss recommendations between the tests in light of these many different perspectives. Finally, we briefly discuss a decision rule for testing genetic neutrality where knowledge of the many perspectives is vital to the proper interpretation of the decision rule.




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Pediatric surgery : a quick guide to decision-making

Roy Choudhury, Subhasis, author.
9789811063046 (electronic bk.)




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Landscape modelling and decision support

9783030374211 (electronic bk.)




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Complete denture prosthodontics : planning and decision-making

Tam protezler. English
9783319690322 (electronic bk.)




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Suntuity AirWorks Offering FREE Assistance in Drone Acquisition...

The drones and programs will be fully paid for by the DOJ as part of the $850 million funding that has been allocated to help public safety departments fight the spread of COVID-19. This includes...

(PRWeb April 30, 2020)

Read the full story at https://www.prweb.com/releases/suntuity_airworks_offering_free_assistance_in_drone_acquisition_through_850mm_federal_grant_assistance_program_for_public_safety_agencies/prweb17090555.htm




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Adaptive risk bounds in univariate total variation denoising and trend filtering

Adityanand Guntuboyina, Donovan Lieu, Sabyasachi Chatterjee, Bodhisattva Sen.

Source: The Annals of Statistics, Volume 48, Number 1, 205--229.

Abstract:
We study trend filtering, a relatively recent method for univariate nonparametric regression. For a given integer $rgeq1$, the $r$th order trend filtering estimator is defined as the minimizer of the sum of squared errors when we constrain (or penalize) the sum of the absolute $r$th order discrete derivatives of the fitted function at the design points. For $r=1$, the estimator reduces to total variation regularization which has received much attention in the statistics and image processing literature. In this paper, we study the performance of the trend filtering estimator for every $rgeq1$, both in the constrained and penalized forms. Our main results show that in the strong sparsity setting when the underlying function is a (discrete) spline with few “knots,” the risk (under the global squared error loss) of the trend filtering estimator (with an appropriate choice of the tuning parameter) achieves the parametric $n^{-1}$-rate, up to a logarithmic (multiplicative) factor. Our results therefore provide support for the use of trend filtering, for every $rgeq1$, in the strong sparsity setting.




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Property testing in high-dimensional Ising models

Matey Neykov, Han Liu.

Source: The Annals of Statistics, Volume 47, Number 5, 2472--2503.

Abstract:
This paper explores the information-theoretic limitations of graph property testing in zero-field Ising models. Instead of learning the entire graph structure, sometimes testing a basic graph property such as connectivity, cycle presence or maximum clique size is a more relevant and attainable objective. Since property testing is more fundamental than graph recovery, any necessary conditions for property testing imply corresponding conditions for graph recovery, while custom property tests can be statistically and/or computationally more efficient than graph recovery based algorithms. Understanding the statistical complexity of property testing requires the distinction of ferromagnetic (i.e., positive interactions only) and general Ising models. Using combinatorial constructs such as graph packing and strong monotonicity, we characterize how target properties affect the corresponding minimax upper and lower bounds within the realm of ferromagnets. On the other hand, by studying the detection of an antiferromagnetic (i.e., negative interactions only) Curie–Weiss model buried in Rademacher noise, we show that property testing is strictly more challenging over general Ising models. In terms of methodological development, we propose two types of correlation based tests: computationally efficient screening for ferromagnets, and score type tests for general models, including a fast cycle presence test. Our correlation screening tests match the information-theoretic bounds for property testing in ferromagnets in certain regimes.




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Sequential decision model for inference and prediction on nonuniform hypergraphs with application to knot matching from computational forestry

Seong-Hwan Jun, Samuel W. K. Wong, James V. Zidek, Alexandre Bouchard-Côté.

Source: The Annals of Applied Statistics, Volume 13, Number 3, 1678--1707.

Abstract:
In this paper, we consider the knot-matching problem arising in computational forestry. The knot-matching problem is an important problem that needs to be solved to advance the state of the art in automatic strength prediction of lumber. We show that this problem can be formulated as a quadripartite matching problem and develop a sequential decision model that admits efficient parameter estimation along with a sequential Monte Carlo sampler on graph matching that can be utilized for rapid sampling of graph matching. We demonstrate the effectiveness of our methods on 30 manually annotated boards and present findings from various simulation studies to provide further evidence supporting the efficacy of our methods.




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Stratonovich stochastic differential equation with irregular coefficients: Girsanov’s example revisited

Ilya Pavlyukevich, Georgiy Shevchenko.

Source: Bernoulli, Volume 26, Number 2, 1381--1409.

Abstract:
In this paper, we study the Stratonovich stochastic differential equation $mathrm{d}X=|X|^{alpha }circ mathrm{d}B$, $alpha in (-1,1)$, which has been introduced by Cherstvy et al. ( New J. Phys. 15 (2013) 083039) in the context of analysis of anomalous diffusions in heterogeneous media. We determine its weak and strong solutions, which are homogeneous strong Markov processes spending zero time at $0$: for $alpha in (0,1)$, these solutions have the form egin{equation*}X_{t}^{ heta }=((1-alpha)B_{t}^{ heta })^{1/(1-alpha )},end{equation*} where $B^{ heta }$ is the $ heta $-skew Brownian motion driven by $B$ and starting at $frac{1}{1-alpha }(X_{0})^{1-alpha }$, $ heta in [-1,1]$, and $(x)^{gamma }=|x|^{gamma }operatorname{sign}x$; for $alpha in (-1,0]$, only the case $ heta =0$ is possible. The central part of the paper consists in the proof of the existence of a quadratic covariation $[f(B^{ heta }),B]$ for a locally square integrable function $f$ and is based on the time-reversion technique for Markovian diffusions.




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High dimensional deformed rectangular matrices with applications in matrix denoising

Xiucai Ding.

Source: Bernoulli, Volume 26, Number 1, 387--417.

Abstract:
We consider the recovery of a low rank $M imes N$ matrix $S$ from its noisy observation $ ilde{S}$ in the high dimensional framework when $M$ is comparable to $N$. We propose two efficient estimators for $S$ under two different regimes. Our analysis relies on the local asymptotics of the eigenstructure of large dimensional rectangular matrices with finite rank perturbation. We derive the convergent limits and rates for the singular values and vectors for such matrices.




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India uses drones to disinfect virus hotspot as cases surge

Indian authorities used drones and fire engines to disinfect the pandemic-hit city of Ahmedabad on Saturday, as virus cases surged and police clashed with migrant workers protesting against a reinforced lockdown. The western city of 5.5 million people in Prime Minister Narendra Modi's home state has become a major concern for authorities as they battle an uptick in coronavirus deaths and cases across India.





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Post-Processing Posteriors Over Precision Matrices to Produce Sparse Graph Estimates

Amir Bashir, Carlos M. Carvalho, P. Richard Hahn, M. Beatrix Jones.

Source: Bayesian Analysis, Volume 14, Number 4, 1075--1090.

Abstract:
A variety of computationally efficient Bayesian models for the covariance matrix of a multivariate Gaussian distribution are available. However, all produce a relatively dense estimate of the precision matrix, and are therefore unsatisfactory when one wishes to use the precision matrix to consider the conditional independence structure of the data. This paper considers the posterior predictive distribution of model fit for these covariance models. We then undertake post-processing of the Bayes point estimate for the precision matrix to produce a sparse model whose expected fit lies within the upper 95% of the posterior predictive distribution of fit. The impact of the method for selecting the zero elements of the precision matrix is evaluated. Good results were obtained using models that encouraged a sparse posterior (G-Wishart, Bayesian adaptive graphical lasso) and selection using credible intervals. We also find that this approach is easily extended to the problem of finding a sparse set of elements that differ across a set of precision matrices, a natural summary when a common set of variables is observed under multiple conditions. We illustrate our findings with moderate dimensional data examples from finance and metabolomics.




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Efficient Acquisition Rules for Model-Based Approximate Bayesian Computation

Marko Järvenpää, Michael U. Gutmann, Arijus Pleska, Aki Vehtari, Pekka Marttinen.

Source: Bayesian Analysis, Volume 14, Number 2, 595--622.

Abstract:
Approximate Bayesian computation (ABC) is a method for Bayesian inference when the likelihood is unavailable but simulating from the model is possible. However, many ABC algorithms require a large number of simulations, which can be costly. To reduce the computational cost, Bayesian optimisation (BO) and surrogate models such as Gaussian processes have been proposed. Bayesian optimisation enables one to intelligently decide where to evaluate the model next but common BO strategies are not designed for the goal of estimating the posterior distribution. Our paper addresses this gap in the literature. We propose to compute the uncertainty in the ABC posterior density, which is due to a lack of simulations to estimate this quantity accurately, and define a loss function that measures this uncertainty. We then propose to select the next evaluation location to minimise the expected loss. Experiments show that the proposed method often produces the most accurate approximations as compared to common BO strategies.




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Data Denoising and Post-Denoising Corrections in Single Cell RNA Sequencing

Divyansh Agarwal, Jingshu Wang, Nancy R. Zhang.

Source: Statistical Science, Volume 35, Number 1, 112--128.

Abstract:
Single cell sequencing technologies are transforming biomedical research. However, due to the inherent nature of the data, single cell RNA sequencing analysis poses new computational and statistical challenges. We begin with a survey of a selection of topics in this field, with a gentle introduction to the biology and a more detailed exploration of the technical noise. We consider in detail the problem of single cell data denoising, sometimes referred to as “imputation” in the relevant literature. We discuss why this is not a typical statistical imputation problem, and review current approaches to this problem. We then explore why the use of denoised values in downstream analyses invites novel statistical insights, and how denoising uncertainty should be accounted for to yield valid statistical inference. The utilization of denoised or imputed matrices in statistical inference is not unique to single cell genomics, and arises in many other fields. We describe the challenges in this type of analysis, discuss some preliminary solutions, and highlight unresolved issues.




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Larry Brown’s Contributions to Parametric Inference, Decision Theory and Foundations: A Survey

James O. Berger, Anirban DasGupta.

Source: Statistical Science, Volume 34, Number 4, 621--634.

Abstract:
This article gives a panoramic survey of the general area of parametric statistical inference, decision theory and foundations of statistics for the period 1965–2010 through the lens of Larry Brown’s contributions to varied aspects of this massive area. The article goes over sufficiency, shrinkage estimation, admissibility, minimaxity, complete class theorems, estimated confidence, conditional confidence procedures, Edgeworth and higher order asymptotic expansions, variational Bayes, Stein’s SURE, differential inequalities, geometrization of convergence rates, asymptotic equivalence, aspects of empirical process theory, inference after model selection, unified frequentist and Bayesian testing, and Wald’s sequential theory. A reasonably comprehensive bibliography is provided.




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Comment: Empirical Bayes, Compound Decisions and Exchangeability

Eitan Greenshtein, Ya’acov Ritov.

Source: Statistical Science, Volume 34, Number 2, 224--228.

Abstract:
We present some personal reflections on empirical Bayes/ compound decision (EB/CD) theory following Efron (2019). In particular, we consider the role of exchangeability in the EB/CD theory and how it can be achieved when there are covariates. We also discuss the interpretation of EB/CD confidence interval, the theoretical efficiency of the CD procedure, and the impact of sparsity assumptions.




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Il faut saisir l'occasion d'assurer une croissance durable, selon la BRI

French translation of BIS press release on the presentation of the Annual Economic Report 2018, 24 June 2018. Les responsables des politiques publiques peuvent prolonger la phase de croissance actuelle en engageant des réformes structurelles, en restaurant les marges de manoeuvre monétaires et budgétaires pour faire face aux menaces futures et en encourageant une mise en oeuvre rapide des réformes réglementaires, indique la Banque des Règlements Internationaux (BRI) dans son Rapport économique annuel. ...




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Exigences de communication financière au titre du troisième pilier - dispositif révisé

French translation of "Pillar 3 disclosure requirements - updated framework", December 2018




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Basilea III: Finalización de las reformas poscrisis

Spanish translation of "Basel III: Finalising post-crisis reforms", December 2017.




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Requisitos de divulgación para el Tercer Pilar - Macro actualizado

Spanish translation of "Pillar 3 disclosure requirements - updated framework", December 2018




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Pablo Hernández de Cos, nombrado Presidente del Comité de Supervisión Bancaria de Basilea

Spanish version of Press release about Pablo Hernández de Cos appointed as Chairman of Basel Committee on Banking Supervision, 7 March 2019. Pablo Hernández de Cos, nombrado Presidente del Comité de Supervisión Bancaria de Basilea.




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Eurovision - :eurovision: