The present invention relates to processes for the crystallisation and for the preparation and isolation of a novel crystalline form of fusidic acid, to the use of said processes in the manufacture of pharmaceutical formulation or medicament, and to the use of said crystalline fusidic acid form for the treatment of bacterial infections.

The invention relates to a cartridge (1) for accommodating blood bags (35), which is provided for the separation of blood components for the application in a centrifuge. The cartridge (1) has a partition wall (3) which separates a blood bag section (5) positioned radially inside from a product section (7) positioned radially outside, and a cover (9) disposed in a mounting position above the blood bag section (5). The cover (9) is connected to the partition wall (3) pivotally in a first point (11) and detachably in a second point (13), so that the blood bag section (5) is freely accessible by means of laterally pivoting the cover (9) out of the way. The cartridge is applicable in the rotor of a centrifuge.

A method for controlling a centrifuge blood component separation system for separating components of a blood product, the separation system comprising a centrifuge and a separation bag and at least one transfer bag. The method comprises selecting a nominal hematocrit value such that an actual hematocrit value is expected to be less than said nominal hematocrit; centrifuging a separation bag containing a volume of composite liquid so as to cause the sedimentation of at least a first component and a second component; transferring some of the first component to a first transfer bag; detecting time of passage of a red blood cell interface at a pre-selected location in the separation bag; and adjusting a predicted processing time based on the time of passage of the red blood cell interface.

The invention is a method of processing tarry or resinous liquids. Tarry liquids include wet scrubber liquids containing tars and chars derived from gasification, pyrolysis or drying of biomass. Resinous liquids include those derived from processing coniferous biomass. Tarry or resinous liquid is processed by a horizontal axis centrifuge having a discharge chamber containing a scraper to prevent centrifuge clogging or fouling. The removed tar and char can be used as solid fuel or recycled to the gasification or pyrolysis process. Polymers, for instance cationic polymers, can be added to the tarry or resin containing liquid prior to centrifugation to assist in solids/liquids separation. Removed resin can be recycled for further use. Tar, char or resin depleted wet scrubber liquid can be recycled for further use or more easily treated prior to disposal.

A cartridge (1) for accommodating blood bags (35) to be inserted into a centrifuge is used for the separation of blood components. Said cartridge (1) is provided with a partition wall (3) which separates a blood bag section (5) positioned radially inside from a product section (7) positioned radially outside, wherein a fixture (29) for a filter (31) is provided in the product section (7), a product transport path (36) which leads from the blood bag section (5) via the fixture (29) for the filter (31) to the product section (7). The product transport path (36) coming from the blood bag section (5) leads into the fixture (29) for the filter (31) radially from the outside and from below.

Provided is a direct thermal media containing a regular repeating pattern of color-forming thermally-imageable stripes printed parallel to the print head element line and a system for using such direct thermal media in color direct thermal printers including an optical registration system optimized for use with this media and an image processing unit that monitors the position of the stripe pattern relative to the print head and synchronizes the start of the printing process. This direct thermal media together with the optical registration system and image processing unit comprise an operative system in that the design of the thermal media, the optical registration system and image processing unit used to control printing are optimized for use with each other. This system may be utilized, for example, in color thermal printers for documents, receipts, tags, tickets or labels.

The present invention relates generally to processes for hydromethanating a carbonaceous feedstock in a hydromethanation reactor to a methane product stream and a char by-product, and more specifically to removal of the char by-product from the hydromethanation reactor.

A method of forming a component (30) by isostatic pressing, the method comprising: providing a canister (4) suitable for isostatic pressing, the canister comprising first and second membranes (14, 16) which, in use, are disposed within the canister (4); the first and second membranes (14, 16) defining a component cavity (24) disposed between the first and second membranes (14, 16), a first tool cavity (26) disposed between the first membrane (14) and an adjacent wall (10) of the canister (4), and a second tool cavity (28) disposed between the second membrane (16) and another adjacent wall (12) of the canister (4); filling the component cavity (24) with the component powder for forming the component (30); filling the first and second tool cavities (26, 28) with a second tool powder; and isostatically pressing the canister (4) to form the component (30).

A combustor includes an end cap having an upstream surface axially separated from a downstream surface. A cap shield circumferentially surrounds the upstream and downstream surfaces, tubes extend from the upstream surface through the downstream, and a plenum is inside the end cap. A first baffle extends radially across the plenum toward the cap shield, and a plate extends radially inside the plenum between the first baffle and the upstream surface. A method for supplying fuel to a combustor includes flowing a working fluid through tubes, flowing a fuel into a plenum between upstream and downstream surfaces, radially distributing the fuel along a first baffle, and axially flowing the fuel across a plate that extends radially inside the plenum.

A technique dynamically configures and verifies routing information of broadcast networks using link state protocols in a computer network. According to the novel technique, a router within the broadcast network receives a link state protocol routing information advertisement from an advertising router, e.g., a designated router or other adjacent neighbor. The router learns of a next-hop router (“next-hop”) to reach a particular destination from the advertisement, and determines whether the next-hop is located within the same broadcast network (e.g., subnet) as the designated router. If so, the router further determines whether the next-hop is directly addressable (i.e., reachable), such as, e.g., by checking for link adjacencies to the next-hop or by sending request/reply messages (e.g., echo messages or “ping” messages) to the next-hop. In the event the next-hop for the destination is not directly addressable by the router (e.g., no adjacency or reply), the router installs a route to the destination via the designated router. Otherwise, the router installs a route to the destination via the next-hop.

Systems and methods provide a parameterized scheduling system that incorporates end-user application awareness and can be used with scheduling groups that contain data streams from heterogeneous applications. Individual data queues within a scheduling group can be created based on application class, specific application, individual data streams or some combination thereof. Application information and Application Factors (AF) are used to modify scheduler parameters such as weights and credits to differentiate between data streams assigned to a scheduling group. Dynamic AF settings may adjust relative importance of user applications to maximize user Quality of Experience (QoE) in response to recurring network patterns, one-time events, application characteristics, protocol characteristics, device characteristics, service level agreements, or combinations thereof. Scheduling parameters may be dynamic and incorporate the notions of “duration neglect” and “recency effect” in an end-user's perception of video quality in order to optimally manage video traffic during periods of congestion.

Methods and apparatus for intercepting communications in an Internet Protocol (IP) network involve maintaining dialing profiles for respective subscribers to the IP network, each dialing profile including a username associated with the corresponding subscriber, and associating intercept information with the dialing profile of a subscriber whose communications are to be monitored. Intercept information will include determination information for determining whether to intercept a communication involving the subscriber, and destination information identifying a device to which intercepted communications involving the subscriber are to be sent. When the determination information meets intercept criteria communications are established with a media relay through which communications involving the subscriber will be conducted or are being conducted to cause the media relay to send a copy of the communications involving the subscriber to a mediation device specified by the destination information.

An energy harvesting system comprises a first region having a first temperature and a second region. A conduit is located at least partially within the first region. A heat engine configured for converting thermal energy to mechanical energy includes a shape memory alloy forming at least one generally continuous loop. The shape memory alloy is disposed in heat exchange contact with the first region and the second region. The shape memory alloy is driven to rotate around at least a portion of the conduit by the response of the shape memory alloy to the temperature difference between the first region and the second region. At least one pulley is driven by the rotation of the shape memory alloy, and the at least one pulley is operatively connected to a component to thereby drive the component.

A sealing arrangement used to create a seal between a first part of a chain and a second part of the chain, wherein the second part can at least be pivoted in relation to the first part, includes a sealing ring with an annular sealing lip for sealing a lubricant area between parts which can be pivoted towards each other, and an elastic ring which is adapted to be fixed to one of the parts and which is adapted to exert pressure in the sealing ring. In addition, a supporting ring is arranged between the sealing ring and the elastic ring.

A continuously variable transmission for a vehicle comprises a primary pulley, a secondary pulley, and a belt entrained around both pulleys in an opposite manner between the fixed and movable sheaves thereof. One pulley carries a selectively deployable stop that may be placed into position to mechanically limit the range of motion between the fixed and movable sheaves. This establishes an actual maximum transmission ratio that is larger than the nominal minimum transmission ratio but smaller than the nominal maximum transmission ratio achievable by the transmission during normal operation thereof. When such a transmission is used on a utility vehicle attached to a substance dispensing applicator operatively driven by the vehicle's engine, the application rate stays substantially constant despite changes in engine speed when the user keeps the transmission upshifted to the actual maximum transmission ratio set by the position of the deployed stop.

An arrangement for supplying oil to a chain drive which drives a transmission oil pump that is axially offset relative to a torque converter and embedded in an intermediate plate in a vehicle having a torque converter. The driven sprocket of the chain drive is supported by a converter neck mounted in a centering plate. A seal is provided between the converter neck and the sprocket and is arranged adjacent the sliding fit between the converter neck and the sprocket. To compensate for the suppression of lubrication of the seal, the neck bearing and the chain drive, a valve is integrated in the intermediate plate, and a duct is provided in the plane, in which the centering plate is screwed to the intermediate plate, such that excess oil flowing from the valve is selectively directed to the seal, the neck bearing and the chain drive.

A method and apparatus for conveying a cellulosic feedstock are disclosed. The apparatus, such as a holding tank, has a passage. At the outlet to the passage, a conveyance member is provided to convey the cellulosic feedstock laterally across the outlet. The conveyance member, e.g., at least one screw conveyor, may have a variable pitch along its length. The method comprises passing the cellulosic feedstock through an impregnation chamber to an outlet of the impregnation chamber; passing the cellulosic feedstock from the outlet of the impregnation chamber to an inlet of a holding tank; passing the cellulosic feedstock downwardly through the holding tank; maintaining a generally constant residence time in the holding tank; and subsequently subjecting the cellulosic feedstock to a hydrolysis process.

An apparatus for conveying a cellulosic feedstock is disclosed. The apparatus comprises an enclosed volume having a lower surface comprising a plurality of longitudinally extending portions. Each longitudinally extending portion has an inner surface that is arcuate in transverse section. A plurality of conveyance members are provided within the enclosed volume. Each conveyance member is associated with one of the inner surfaces and configured to sweep the one of the inner surfaces. Additionally, a method for treating a cellulosic feedstock is disclosed. The method comprises providing a cellulosic feedstock being less than 100% saturated moisture. The cellulosic feedstock is introduced into a longitudinally extending enclosed volume, and conveyed longitudinally through the enclosed volume while being mixed.

A process for preparing the compound of the following formula (E): wherein Bn represents a benzyl group, and tBu represents a tert-butyl group, the process including: (a) subjecting the following compound (B) to trifluoroacetylation, wherein tBu represents a tert-butyl group to produce the following compound (C): wherein tBu represents a tert-butyl group, and TFA represents a trifluoroacetyl group; (b) reacting the compound (C) with benzyloxyamine in the presence of a hydroxyl group activating agent to produce the following compound (D): wherein Bn represents a benzyl group, tBu represents a tert-butyl group, and TFA represents a trifluoroacetyl group; and (c) subjecting the compound (D) to detrifluoroacetylation.

A magnetized nut for fastening a compressor wheel of an exhaust turbocharger to a turbo shaft. The nut has a base body made of a non-magnetic material forming a hollow space for accommodating a magnetic material, and a method for the production of the magnetized nut. In order to provide a magnetized nut that is produced in a simple and cost-effective manner and ensures as equal a distribution of mass as possible with regard to the rotational axis of the nut, the magnetic material is introduced into the hollow space using injection molding.

A clinch-type fastener is formed by simultaneously creating an undercut during the same forging that creates the head and displacer of the fastener. A fastener blank is compressed end-to-end between top and bottom dies whereby the axial compression of a blank causes the outward bulging of the shank at its midline. Simultaneously, a tapered end point and a tangential interference band are formed provided by a curvilinear-shaped bulge in the shank. As the bulge is formed an undercut is created between the bulge and a shoulder which extends downwardly from a head of the fastener. This method of formation and the fastener produced thereby are particularly suited to the manufacture of small clinch pins having a diameter in the range of 1.0 mm.

An abrasive tool including a CMP pad conditioner having a substrate including a first major surface, a second major surface opposite the first major surface, and a side surface extending between the first major surface and the second major, wherein a first layer of abrasive grains is attached to the first major surface and a second layer of abrasive grains is attached to the second major surface. The conditioner further includes a first sealing member extending in a peripheral direction along a portion of the side surface of the substrate.

A tool is disclosed for selective honing of the outer diameter of a cylinder using an abrasive belt in semi-circular contact upon the outer-diameter of a cylindrical work-piece to perform a similar function to honing the inner-diameter of a hollow cylinder. The belt is retained within the tool body by U-shaped restraint arms, and a slot in the tool body. A clamp block retains the ends of the belt which exit the slot. Springs on the arms, and contact of the block on the outside of the tool body, force the belt into a triangular shape inside the body. A cylindrical work-piece inserted within the triangular shaped belt causes the belt to deform into three semi-circular areas of contact between the belt and work-piece. When the work-piece is rotated, the belt abrades material from the work-piece.

A carriage is moved in a direction including a Y axis component in order to move a turning process tool that is attached to a tool spindle along a horizontal line that is perpendicular to a Z axis, and thus, a turning process is carried out on a workpiece which is attached to a workpiece spindle.

A tool changing device for a cutting head of a machine for cutting flat glass sheets, the tool changing device comprising: a bridge; a carriage for supporting the cutting head, the carriage being slidingly attached to the bridge for translation along the bridge; an electric motor that provides for translational motion of the carriage with respect to the bridge; and a tool supporting slider, which is configured to support a plurality of tools such that the tools can be automatically exchanged between the tool supporting slider and the cutting head, the tool supporting slider coupled, by way of reversible fixing elements to the cutting head supporting carriage during work by the cutting head, and wherein the tool supporting slider is uncoupled from the cutting head supporting carriage during tool changing operations.

Embodiments of the present disclosure provide methods for allocating bandwidth to a plurality of traffic containers of a passive optical network. The method comprises receiving upstream data from a plurality of traffic containers of the passive optical network and passing the upstream data to a traffic manager. The method further comprises dynamically changing the allocated bandwidth based at least in part on the amount of the upstream data stored in one or more queues of the traffic manager.

The invention provides optical interconnects of data-processing cores of multicore chips by means of digital planar holographic microchips. The method comprises delivering “N” laser lights to “N” data-processing cores on the host chip, coding the obtained optical signals by modulating them with the core-generated data, and then delivering the modulated and coded optical signals to a holographic microchip formed on the same substrate of the host chip as the data-processing cores, splitting the modulated and coded optical signals into (N−1)N modulated optical copy signals, delivering the copy signals to all data-processing cores except the one that generates the copy signals, and decoding the data obtained from the output signals delivered to the processing cores by the receivers. The method is efficient in that it allows replacing electrical interconnects between the cores with optical interconnects and can be matched to current semiconductor production technology.

Intrapersonal communication systems and methods that provide an optical digital signal link between two or more local devices are disclosed. In some embodiments, the system includes a first signal converter disposed at a first end of the optical digital signal link and configured to convert between electrical digital signals from a first local device and optical digital signals from the optical digital signal link. The system can include an optical connector having a non-contact portion configured to couple optical digital signals between the first signal converter and the optical digital signal link across a gap. The system can include a second signal converter disposed at a second end of the optical digital signal link and configured to convert between electrical digital signals from the second local device and optical digital signals from the optical digital signal link.

In a cutting tool for chip removing machining a holder for a cutter has a body received therein and movable with surfaces to bear against the cutter for defining the position of the cutter in the direction of an intended axis of rotation of the holder as well as a screw which may be screwed in a threaded bore in the holder. Spring members are arranged to act between the holder and the body for biasing the body against said screw portions.

A cutting insert (14) is formed with an insert aperture (32) opening out to insert top and bottom surfaces (14A, 14B) of the cutting insert (14). In a plan view of the insert top surface (14A), the cutting insert (14) and the insert aperture (32) both have oblong shapes which are elongated along a common insert longitudinal axis (AIL). The aperture (32) includes first and second side surfaces (32A1, 32A2) which each extend along the insert longitudinal axis (AIL), and aperture first and second end surfaces (32B1, 32B2) which each extend transverse relative to the insert longitudinal axis (AIL). At least one of the aperture first and second end surfaces (32B1, 32B2) is formed with a clamping lip (32C1, 32C2).

A compression dressing and method of use is provided. The dressing is self-adherent, washable and reusable and provides a selected and generally constant pressure to the surface of an animal.

A component part has a catalyst surface. This surface has metallic components and components of MnO2 (13) in contact with the former. The metallic components are preferably formed of Ag and/or Ni. These material pairs achieve a great improvement in catalyst action compared to the pure metals. Especially in the case of use of Ni, which is toxicologically safe, these surfaces, for example, may also find use in ambient air purification for reduction of the ozone content. The surface can be applied, for example, by a coating of the component part, in which case the metallic component and the component of MnO2 are applied in two layers.

Apparatus and method are provided for electric induction heating and/or stirring of a molten electrically conductive composition in a containment vessel with the apparatus being removably insertable in the molten composition. An induction coil embedded in refractory or a coating is submerged in the composition and used to heat and/or stir the molten composition either externally or internally to the refractory or coating.

A device is described for generating a control signal for controlling a passenger protection arrangement of a motor vehicle, having a first acceleration sensor for generating a first acceleration signal, having a second acceleration sensor for generating a second acceleration signal, having a first structure-borne noise sensor for generating a first structure-borne noise signal, having a second structure-borne noise sensor for generating a second structure-borne noise signal, and having an evaluation circuit, the evaluation circuit (being configured for generating a combination signal from the first structure-borne noise signal and the second structure-borne noise signal, the evaluation circuit being configured for generating the control signal as a function of the first acceleration signal, the second acceleration signal and the combination signal.

Method of manufacturing a fused silica crucible, including manufacturing a plurality of carbon electrodes for melting a vitreous silica object to be melted by arc discharge by rubbing the surface of a carbon electrode of the electrodes with a vitreous silica of the same type as the vitreous silica object to be melted, by at least one of: inserting a front end of the carbon electrode into a storage tank storing powdered vitreous silica, by at least one of rotating and reciprocating in an axial direction the storage tank and the carbon electrode relative to each other; rubbing the surface of the carbon electrode by ejecting powdered vitreous silica from a nozzle onto the surface of the electrode; rubbing the surface of the electrode with a vitreous silica grinder; and rubbing the surface of the electrode against a rotating surface of a portion of a fused vitreous silica crucible.

An input shaft assembly is movable along an axis to absorb external impact loads. A biasing member exerts an axial load in a direction counter to potential impact loads. A stop is provided to control the application of biasing loads to control application of such axial load.

An energy-reducing method and apparatus for retrofitting a single zone, constant volume HVAC system, with or without an economizer, that provides heating, cooling, and ventilation to occupants within a building space. The present invention includes the introduction of a programmable logic controller and variable frequency drive (VFD) that takes control of the existing fan, heating, cooling, and optional economizer operation. The reduction of the fan speed in the ventilation mode when the 100% operation is not needed saves significant energy of the existing constant volume HVAC system where the fan motor is designed to run 100% of the time.

This invention relates to novel Ln(III) complexes of pybox, and methods of making the same. The present invention also relates to a method of use of pybox as a chelating moiety and sensitizer for Ln(III) ion luminescence. Derivatives of pybox and methods of making the same are also provided.

Disclosed herein is a GO-Gd-DTPA (gadolinium-diethylenetriamine pentaacetic-graphene oxide) complex, which is formed by an ester bond of graphene oxide (GO) and gadopentetic acid (Gd-DTPA). Since the GO-Gd-DTPA can stably exist in the body because it has high stability in water, it is expected that it can be effectively used as an MRI contrast agent.

A hypoxia contrast medium including nitroimidazole-amino acid chelate with a positively charged radioactive nuclide, a preparation method and use thereof. The contrast medium can be used in imaging cerebral thrombosis, tumors or other diseases such as ulceration, thrombosis, and so on.

A method of injecting mortar into a container fastened to a first tank and to a second tank, the first tank communicating with the container via a first orifice and the second tank communicating with the container by a second orifice, the method comprising the following operations: a continuous circulation of a first stream of mortar is made to flow in a circulation loop; during the continuous circulation, a second stream of mortar is drawn off from the circulation loop, the second stream being smaller than the first stream of mortar; the second stream of mortar is injected into the container, ensuring that there is dynamic confinement of the gaseous effluents; and the appearance of mortar in the second tank is monitored and, when this appearance is detected, the removal of mortar from the circulation loop is brought to an end.

A method for measuring the neutron flux in the core of a nuclear reactor, the method including several steps recurrently performed at instants separated by a period, the method comprising at each given instant the following steps: acquiring a total signal by a cobalt neutron detector placed inside the core of the reactor; assessing a calibration factor representative of the delayed component of the total signal due to the presence of cobalt 60 in the neutron detector; assessing a corrected signal representative of the neutron flux at the detector from the total signal and from the calibration factor; assessing a slope representative of the time-dependent change of the calibration factor between the preceding instant and the given instant; the calibration factor at the given instant being assessed as a function of the calibration factor assessed at the preceding instant, of the slope, and of the time period separating the given instant from the preceding instant.

In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.

A system or method for inferring and selective display of visual and sound media content based on a pet(s)'s level of engagement or reactions to content displayed on any number of content display devices including, but not limited to, television screens, computer monitors, tablets, and cell phones and measured by a sensor. A content selection algorithm takes as input the sensor measurements and historical or pre-computed data to infer the pet(s)'s preference for content. A content modification algorithm interposes algorithmically computed shapes and sounds overlaid on top of the existing content to attract the attention of the pet(s) observing the display.

An automatic content recognition (ACR)-enabled connected TV device may be associated with a paired device and the paired device may comprise a browser. The ACR-enabled connected TV device may be operable to enable, utilizing an ACR system, the browser to display, within a section of a browser window, interactive content related to certain content being presented by the ACR-enabled connected TV device. The ACR-enabled connected TV device may be operable to enable, utilizing the ACR system, a viewer to interact with the interactive content. The section of the browser window may be changed dynamically. The certain content may comprise an advertisement of a particular product and the interactive content may comprise a link to a website and/or other information related to the particular product. The certain content may comprise a program associated with a network and the interactive content may comprise information on polling questions related to the program.

An exemplary method includes a media service provider system 1) providing an end user of an integrated media service with access to a media program by way of a plurality of different media distribution models, 2) maintaining a catalog that includes comprehensive information about the media program, the comprehensive information being an aggregate of non-redundant information about the media program obtained from a plurality of independent source catalogs corresponding to the plurality of different media distribution models, and 3) providing, based on the comprehensive information included in the catalog, a media service user interface that supports discovery of the comprehensive information about the media program regardless of a user interface context from which a user request for information about the media program is received. Corresponding systems and methods are also described.

A method and system of providing a content guide that identifies a spatial relationship between the elements in the content guide is described. A controller receives electronic program guide data. The received electronic program guide data is parsed to identify a plurality of programs listed in the electronic program guide and data corresponding to at least one program description attribute for the identified programs. A relationship is determined between each identified program based on the at least one program description attribute. At least one cluster is generated and includes at least one of the plurality of identified programs based on the determined relationship. A user interface display processor generates a user interface display image representing a clustered content guide and including the at least one generated cluster enabling the user to view the relationship of the plurality of programs.

Systems and methods for optimizing system performance of capacity and spectrum constrained, multiple-access communication systems by selectively discarding packets are provided. The systems and methods provided herein can drive changes in the communication system using control responses. One such control responses includes the optimal discard (also referred to herein as “intelligent discard”) of network packets under capacity constrained conditions. Some embodiments inspect a video stream to determine priorities for various elements of the video stream. The elements may be discarding using the priorities. In various embodiments, the elements include frames, slices, macroblocks, and data partitions.

Self-assembled silica condensates are described as well as their use in coating compositions. The self-assembled silica condensates can be formed from the hydrolysis of medium to long chain trialkoxy silane compounds. Coating compositions containing the self-assembled silica condensates can provide coatings having improved scratch and mar resistance and can have excellent recoat adhesion.

Disclosed is a drug effective in the treatment of fibromyalgia. Basically, the disclosed therapeutic agent was created on the basis of experiments showing improvement in symptoms when etanercept was administered to patients suffering from fibromyalgia. Etanercept is known as a therapeutic agent for rheumatoid arthritis, and the JFIQ score of patients not suffering from fibromyalgia improved considerably in the preferred embodiment. In other words, a therapeutic agent for fibromyalgia is disclosed that contains etanercept as an active ingredient in an effective amount.