no

[ASAP] Furofuranone Lignans from <italic toggle="yes">Leucophyllum ambiguum</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00759




no

[ASAP] Irijimasides A–E, Macrolide Glycosides from an <italic toggle="yes">Okeania</italic> sp. Marine Cyanobacterium

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00042




no

[ASAP] Genomics–Metabolomics Profiling Disclosed Marine <italic toggle="yes">Vibrio spartinae</italic> 3.6 as a Producer of a New Branched Side Chain Prodigiosin

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01159




no

[ASAP] Spongian Diterpenoids Derived from the Antarctic Sponge <italic toggle="yes">Dendrilla antarctica</italic> Are Potent Inhibitors of the <italic toggle="yes">Leishmania</italic> Parasite

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00025




no

[ASAP] 6-Deoxy- and 11-Hydroxytolypodiols: Meroterpenoids from the Cyanobacterium HT-58-2

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00844




no

[ASAP] Bioactive <italic toggle="yes">seco</italic>-Sativene Sesquiterpenoids from an <italic toggle="yes">Artemisia desertorum</italic> Endophytic Fungus, <italic toggle="yes">Cochliobolus sativ

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01148




no

[ASAP] Irpexine, an Isoindolinone Alkaloid Produced by Coculture of Endophytic Fungi, <italic toggle="yes">Irpex lacteus</italic> and <italic toggle="yes">Phaeosphaeria oryzae</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00047




no

[ASAP] Kalparinol, a Salvialane (Isodaucane) Sesquiterpenoid Derived from Native Australian <italic toggle="yes">Dysphania</italic> Species That Suggests a Putative Biogenetic Link to Zerumbone

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01039




no

[ASAP] Unprecedented Quassinoids from <italic toggle="yes">Eurycoma longifolia</italic>: Biogenetic Evidence and Antifeedant Effects

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00244




no

[ASAP] Phenylpropanoid-Conjugated Triterpenoids from the Leaves of <italic toggle="yes">Actinidia arguta</italic> and Their Inhibitory Activity on a-Glucosidase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00643




no

[ASAP] Sesquiterpenoids from Cultures of the Basidiomycetes <italic toggle="yes">Irpex lacteus</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01177




no

[ASAP] The Oxidation of Phytocannabinoids to Cannabinoquinoids

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01284




no

[ASAP] Cyperane-Type and Related (Nor)Sesquiterpenoids from the Root Bark of <italic toggle="yes">Acanthopanax gracilistylus</italic> and Their Inhibitory Effects on Nitric Oxide Production

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00913




no

[ASAP] Psathyrins: Antibacterial Diterpenoids from <italic toggle="yes">Psathyrella candolleana</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00269




no

[ASAP] Isolation of Taste-Active Triterpenoids from <italic toggle="yes">Quercus robur</italic>: Sensory Assessment and Identification in Wines and Spirit

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00106




no

[ASAP] Total Synthesis of Isohericenone J via a Stille Coupling Reaction

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01251




no

[ASAP] Iheyamides A–C, Antitrypanosomal Linear Peptides Isolated from a Marine <italic toggle="yes">Dapis</italic> sp. Cyanobacterium

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00250




no

[ASAP] Cytotoxic Monoterpenoid Indole Alkaloids from <italic toggle="yes">Tabernaemontana corymbosa</italic> as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00856




no

[ASAP] Review of Progress in the Chemistry of Organic Natural Products<source>Progress in the Chemistry of Organic Natural Products</source>, Volume 108. Edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun’ichi Kobayashi, Yoshinori A

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00356




no

[ASAP] Cucurbitane-Type Triterpenoids from the Vines of <italic toggle="yes">Momordica charantia</italic> and Their Anti-inflammatory Activities

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00592




no

[ASAP] Bromo-spiroisoxazoline Alkaloids, Including an Isoserine Peptide, from the Caribbean Marine Sponge <italic toggle="yes">Aplysina lacunosa</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01286




no

[ASAP] Effect of Temperature on <sup>1</sup>H NMR Spectra, Antitrypanosomal Activity, Conformational Analysis, and Molecular Docking of Curine Derivatives from <italic toggle="yes">Berberis brevissima</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00397




no

[ASAP] Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00014




no

[ASAP] <italic toggle="yes">Streptomyces albogriseolus</italic> SY67903 Produces Eunicellin Diterpenoids Structurally Similar to Terpenes of the Gorgonian <italic toggle="yes">Muricella sibogae</italic>, the Bac

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00147




no

[ASAP] Inhibitory Effect of Cannabidiol on the Activation of NLRP3 Inflammasome Is Associated with Its Modulation of the P2X7 Receptor in Human Monocytes

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00138




no

[ASAP] A Grand Challenge. 3. Unbiased Phenotypic Function of Metabolites from Australia Plants <italic toggle="yes">Gloriosa superba</italic> and <italic toggle="yes">Alangium villosum</italic> against Parkinson

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00880




no

[ASAP] Advances in the Biosynthesis of Pyranocoumarins: Isolation and <sup>13</sup>C-Incorporation Analysis by High-Performance Liquid Chromatography–Ultraviolet–Solid-Phase Extraction–Nuclear Magnetic Resonance Data

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00607




no

[ASAP] Stoechanones A and B, Phytotoxic Copaane Sesquiterpenoids Isolated from <italic toggle="yes">Lavandula stoechas</italic> with Potential Herbicidal Activity against <italic toggle="yes">Amaranthus retroflexus<

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00182




no

Highlight.js 10, Node 14, and modern React in 20 minutes

#485 — April 24, 2020

Unsubscribe  :  Read on the Web

JavaScript Weekly

Introducing Crank.js: A New JSX-Driven Framework — A new framework for creating JSX-driven components with functions, promises and generators. If you haven’t got time to read the creator’s lengthy (but well worth reading!) rationale for creating another framework, check out the GitHub repo or jump straight into a CodeSandbox example. I hope to see a lot more about this in the near future.

Brian Kim

The Cost of JavaScript Frameworks — Using data from the HTTP Archive, Tim explores the performance cost of using various popular frameworks as a starting point. Some good analysis here.

Tim Kadlec

You Hacked the Gibson? Yeah, They Built Their Own Login — Don't let Crash Override pwn your app. FusionAuth adds secure login, registration and user management to your app in minutes not months. Download our community edition for free.

FusionAuth sponsor

Node.js 14 Released — v14 now becomes the current ‘release’ line with it becoming a LTS (Long Term Support) release in October. Diagnostic reports are now a stable feature, it now uses V8 8.1, there's an experimental Async Local Storage API, and more.

Michael Dawson and Bethany Griggs

Vidact: A Compiler to Convert React-like Apps to Vanilla JS — Compiles pure React-compatible JavaScript (JSX) to vanilla JavaScript with no virtual DOM.. think similar to Svelte, but without introducing a new syntax. A curious idea.

Mohamad Mohebifar

Highlight.js 10.0: The Web Syntax Highlighter Library — I always laugh when I see a big release of a popular library and saw we last linked it 5 years ago ???? Nonetheless, this is a big release and Highlight.js continues to be a fantastic library for syntax highlighting code.

highlight.js

???? Jobs

Senior Full-stack Developer (Malmö/Sweden) — Every day is different from the next. Join our upbeat Team and work on exciting, major projects using a modern JavaScript stack.

Ortelius AB

Find a Job Through Vettery — Vettery specializes in tech roles and is completely free for job seekers. Create a profile to get started.

Vettery

???? Tutorials

▶  React: The Basics in 20 Minutes — A well presented, up to date (yep, it covers hooks) tutorial that doesn’t hang around, whether you’re new to React or just want a refresher.

Devistry

Creating Web Apps via TypeScript and webpack — The example app doesn’t use any front-end framework, just vanilla DOM APIs. Some knowledge of TypeScript, webpack, and npm are required, but this is a neat way to bring together a bunch of tools.

Axel Rauschmayer

What Is The toJSON() Function? — If an object has a toJSON function, JSON.stringify() calls toJSON() and serializes the return value from toJSON() instead.

Valeri Karpov

A Much Faster Way to Debug Code Than with Breakpoints or console.log — Move forward and backwards through your code to understand what led to a specific bug, view runtime values, edit-and-continue, and more.

Wallaby.js sponsor

How Does TypeScript Work? A Bird’s Eye View — Dr. Axel goes into depth on the structure of a typical TypeScript project, what gets compiled, and how can an IDE be used to write TypeScript. Aimed at people who haven’t yet picked TypeScript up.

Axel Rauschmayer

10 Lesser Known Angular Features You've Probably Never Used

W3Radar

You Might Not Need switch — Using an object of outcomes instead of switch suits many use cases, though take care over readability.

Valentino Gagliardi

???? Upcoming Online Events

  • Pick JS (May 8) — Aimed at intermediate to expert JS developers rather than beginners.
  • JavaScript Remote Conf 2020 (May 14-15) — Speakers lined up already include Douglas Crockford, Aimee Knight and Christian Heilmann.
  • ESNEXT CONF 2020 (May 18-22) — From the Pika folks (of Snowpack fame). 12 speakers over 5 days so it's a gradual pace.
  • ForwardJS (May 26-29) — A real world event (ForwardJS Ottawa) that has now become a virtual event.
  • CascadiaJS 2020 (September 1-2) — This upcoming online conference is set to take place in September, and the CFP is open now through May 15.

???? Code & Tools

Phelia: A Reactive Slack Application Framework — If you think Slack apps were all about text bots, think again.. you can now create apps complete with in-app UIs. Phelia brings the React approach to the task.

Max Chehab

Marked.js 1.0: A Fast Markdown Parser and Compiler — Got Markdown to render? Marked.js to the rescue. While the project is years old, 1.0 has dropped just this week. Here’s a live demo.

Christopher Jeffrey

Stream Chat API & JavaScript SDK for Custom Chat Apps — Build real-time chat in less time. Rapidly ship in-app messaging with our highly reliable chat infrastructure.

Stream sponsor

Alpine.js: A Minimal Framework for Composing JS Behavior in Your Markup — We only gave Alpine a brief link when it first dropped but with new versions coming out thick and fast, we think it’s well worth a look. Billed as “like Tailwind for JavaScript”, Alpine lets you keep the HTML you know and love and just pepper it with JavaScript as and where appropriate.

Alpine.js

enroute: A React Router with a Small Footprint for Modern Browsers

TJ Holowaychuk

Rosetta: A General Purpose Internationalization Library in 292 Bytes — Less than 300 bytes, but does have a few dependencies. Aims to be very simple and is targeted at basic string use cases.

Luke Edwards

NAB 2020 May Be Canceled, But The Full Bitmovin Experience Is Not

Bitmovin Inc. sponsor

Hotkey 1.4: Trigger an Action on an Element When a 'Hotkey' is Pressed — Use Hotkey, set the data-hotkey attribute on your elements, and you get keyboard shortcuts. GitHub built and uses it (look for the data-hotkey attributes on their pages).

GitHub

web-worker: Consistent Web Workers for the Browser and Node — In Node it works as a web-compatible Worker implementation atop worker_threads. In the browser it’s an alias for Worker.

Jason Miller




no

Nirmala Sitharaman's Budget proposals to stimulate economic growth

The tax proposals are aimed at stimulating growth, simplifying tax structure, bringing ease of compliance and reducing litigation




no

Not all NRIs need to pay tax, here's what FM clarified post budget speech

Finance minister clarified that only Indian income of NRIs is proposed to be taxed under the new provision




no

Budget: No tax relief for home buyers stuck in stalled projects, says FPCE

Real estate developers' apex bodies CREDAI and Naredco have also expressed disappointment over the Budget as their demand of one-time restructuring of builders' loan was not met




no

Govt not included AGR dues payment in Budget 2020-21: DEA Secretary

15 entities owe the government about Rs 1.47 trillion in past dues -- Rs 92,642 crore in unpaid licence fee and another Rs 55,054 crore in outstanding spectrum usage charges




no

Budget 2020 has not accounted for telcos' AGR dues: DEA secretary

But receipts from firms stand at a whopping Rs 1.33 trillion for FY21




no

Budget 2020: Rs 2,500 cr not enough for tourism promotion, says industry

Tourism bodies say Indians spending Rs 9,000 cr abroad abroad due to poor domestic infra, which cannot be improved with this allocation




no

Economy fundamentals strong; markets show faith in Budget 2020: Sitharaman

FM says country's macroeconomic parameters are sound




no

Objective of kick-starting growth not addressed effectively in Budget: Garg

"All these expenditures are unlikely to be imparting any fresh growth stimulus to the Indian economy," he argued




no

No timeline to remove income tax exemptions, says Nirmala Sitharaman

"We have not made up our minds as yet (on the removal of all exemptions)... We are trying step by step, move forward and no particular timeline given," she said




no

Prevention of Melanoma With Regular Sunscreen Use

Interview with June K. Robinson, MD, author of Prevention of Melanoma With Regular Sunscreen Use




no

Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage

Interview with J. Michael McWilliams, MD, Phd, author of Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage




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Quality of Life, Burnout, Educational Debt, and Medical Knowledge Among Internal Medicine Residents

Interview with Colin P. West, MD, PhD, author of Quality of Life, Burnout, Educational Debt, and Medical Knowledge Among Internal Medicine Residents




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Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial

Interview with Jay H. Traverse, MD, author of Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial




no

Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial

Interview with Steven E. Nissen, MD, author of Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial




no

Amoxicillin for Acute Rhinosinusitis: A Randomized Controlled Trial

Interview with Jay F. Piccirillo, MD, author of Amoxicillin for Acute Rhinosinusitis: A Randomized Controlled Trial




no

Utilization of Anesthesia Services During Outpatient Endoscopies and Colonoscopies and Associated Spending in 2003-2009

Interview with Soeren Mattke, MD, DSc, author of Utilization of Anesthesia Services During Outpatient Endoscopies and Colonoscopies and Associated Spending in 2003-2009




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Healthy Men Should Not Take Statins

Interview with Rita F. Redberg, MD, author of Healthy Men Should Not Take Statins




no

JAMA: 2012-04-11, Vol. 307, No. 14, Author Interview

Interview with Donald M. Berwick, MD, MPP, author of Eliminating Waste in US Health Care




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Effect of Continuous Positive Airway Pressure on the Incidence of Hypertension and Cardiovascular Events in Nonsleepy Patients With Obstructive Sleep Apnea: A Randomized Controlled Trial

Interview with Ferran Barbé, MD, author of Effect of Continuous Positive Airway Pressure on the Incidence of Hypertension and Cardiovascular Events in Nonsleepy Patients With Obstructive Sleep Apnea: A Randomized Controlled Trial




no

Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010

Interview with Rebecca Smith-Bindman, MD, author of Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010




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The Next Generation of Obesity Research: No Time to Waste

Interview with Griffin P. Rodgers, MD, author of The Next Generation of Obesity Research: No Time to Waste