Casais com problemas de fertilidade que estavam passando por processo de fertilização in vitro no Brasil temem perder chance de ter filhos por causa da pandemia.

Eduardo Massad diz que próxima pandemia depois de coronavírus deve ser avassaladora e defende que o mundo aprenda mais sobre medidas de distanciamento social.

According to the news release, the NBA will use this hiatus to determine next steps for moving forward in regard to the coronavirus pandemic.

Dallas Mavericks owner and IU alum is taken aback to learn the NBA is stopping play in the wake of a player's coronavirus test

First-half incident resulted in an ejection for Illini player as he stepped on Boilermakers guard

Late Tuesday night, police officers in Visalia, a San Joaquin Valley city about 40 miles southeast of Fresno, responded to a report of shots fired at a high school.

Eight suspected illegal miners, known as zama zamas, have been arrested in Limpopo, following a Hawks investigation.

After three decades of mystery, the cold case murder of a 17-year-old Ohio teen named Barbara Blatnik has been solved thanks in part to DNA genealogical research. The last time anyone saw Blatnik alive was around midnight on Dec. 19, 1987, when a friend dropped her off in Garfield Heights, Ohio. The following day, Blatnik,…

The post 32 Years After Teen’s Body Found Strangled on Side of Road, Suspect Finally Arrested appeared first on The Western Journal.

A transit centre in north Edmonton was evacuated for about two hours Saturday morning due to a suspicious package.

Studies demonstrate that the investigational ⁶⁴Cu-DOTATATE radiopharmaceutical may provide diagnostic and logistical benefits over available imaging agents for patients with somatostatin receptor (SSTR)-positive neuroendocrine tumors (NETs). Accordingly, we aimed to prospectively determine the lowest dose of ⁶⁴Cu-DOTATATE that facilitates diagnostic quality scans and evaluated the diagnostic performance and safety in a phase III study of patients with SSTR-expressing NETs. Methods: A dose-ranging study was conducted in 12 patients divided into 3 dose groups (111 MBq [3.0 mCi], 148 MBq [4.0 mCi], and 185 MBq [5.0 mCi] ± 10%) to determine the lowest dose of ⁶⁴Cu-DOTATATE that produced diagnostic quality PET/CT images. Using the ⁶⁴Cu-DOTATATE dose identified in the dose-ranging study, 3 independent nuclear medicine physicians who were blinded to all clinical information read PET/CT scans from 21 healthy volunteers and 42 NET-positive patients to determine those with "Disease" and "No Disease," as well as "Localized" versus "Metastatic" status. Blinded-reader evaluations were compared to a patient-specific standard of truth (SOT), which was established by an independent oncologist who used all previously available pathology, clinical, and conventional imaging data. Diagnostic performance calculated for ⁶⁴Cu-DOTATATE included sensitivity, specificity, negative predictive value, positive predictive value, and accuracy. Inter- and intra-reader reliability, as well as ability to differentiate between localized and metastatic disease, was also determined. Adverse events (AEs) were recorded from ⁶⁴Cu-DOTATATE injection through 48 hours post-injection. Results: The dose-ranging study identified 148 MBq (4.0 mCi) as the optimal dose to obtain diagnostic quality PET/CT images. Following database lock, diagnostic performance from an initial majority read of the 3 independent readers showed a significant 90.9% sensitivity (P = 0.0042) and 96.6% specificity (P < 0.0001) for detecting NETs, which translated to a 100.0% sensitivity and 96.8% specificity after correcting for an initial SOT misread. Excellent inter- and intra-reader reliability, as well as ability to distinguish between localized and metastatic disease, was also noted. No AEs were related to ⁶⁴Cu-DOTATATE, and no serious AEs were observed. Conclusion: ⁶⁴Cu-DOTATATE PET/CT is a safe imaging technique that provides high-quality and accurate images at a dose of 148 MBq (4.0 mCi) for the detection of somatostatin-expressing NETs.

Acute respiratory distress syndrome was first described in 1967 and has become a defining condition in critical care. Around 40% of patients with ARDS will die, and survivors experience long term sequelae. No drug treatments exist for ARDS, however good supportive management reduces harm and improves outcome. In this podcast, John Laffey,...

Springfield, Virginia — The Drug Enforcement Administration announced that effective March 23, the DEA Call Center has temporarily suspended phone operations due to COVID-19 pandemic.

Hundreds attended a rally Friday in support of Ahmaud Arbery, and officials said they will investigate the man who recorded a video of his shooting.

Ohio Gov. John Kasich is expected to sign a bill into law that would ban suspensions and expulsions for children in prekindergarten through 3rd grade for minor offenses.

Now Newark, New Jersey, is exploding, thanks to the attempts at intimidation by Governor Christie's hand-picked superintendent of schools, Cami Anderson.

Wien : C. Ueberreuter, 1860.

Paris : Steinheil, 1888.

A physiotherapist in Thunder Bay, Ont., has had his licence suspended until September, as part of a disciplinary hearing.

Provincial Police have a suspect in custody after a firearms incident Thursday morning at the hospital in the small northwestern Ontario community of Rainy River.

Police are investigating a report of a suspicious package in north Edmonton.

Cleveland Indians reliever Emmanuel Clase was suspended 80 games by Major League Baseball on Friday for testing positive for a banned performance-enhancing drug.

A Winnipeg School Division trustee who was suspended from the school board earlier this week does not plan on fighting the decision, she told CBC News.

As a result of the pandemic, USPS, which has run at a loss for years, is even more cash-strapped. It expects to lose $2 billion each month during the pandemic. That prompted Postmaster General Megan Brennan to ask Congress for $50 billion in funds -- $25 billion to offset lost revenue from declining mail volume due to the pandemic, and another $25 billion for modernization.

The leader of a First Nation surrounded by oilsands development is frustrated by the Alberta Energy Regulator's decision to suspend a wide array of environmental reporting requirements for oilsands companies.

Waterloo regional police have charged three people and identified a suspect in a fatal February hit and run on Highland Rd. W.

Police say the two men, ages 38 and 45, were confined and assaulted in a motel in the 600 block of Idylwyld Drive on Tuesday between 4 p.m. and 7 p.m. CST.

TransLink is suspending the service reductions it planned for later this month and is rescinding layoff notices to around 1,500 employees.

YouthTruth asked 104,000 school staff, students, and their families how they perceive the fairness of discipline at their schools. The results can help start conversations about discipline policy and leading by listening.

Most teachers say that school discipline is inconsistent or inadequate, a new study from the Fordham Institute finds.

Clinical guidelines for the evaluation of suspected physical abuse in young children emphasize performing radiologic imaging to screen for occult fractures. Little is known about the degree of adherence to guidelines for screening for occult fractures among pediatric hospitals.

Adherence to guidelines related to screening for occult fractures in young children diagnosed with physical abuse varies significantly among pediatric hospitals. Use of screening in infants who have injuries associated with a high likelihood of abuse also varies among pediatric hospitals. (Read the full article)

Although appendicitis is the most common surgical cause of abdominal pain in pediatrics, its diagnosis remains elusive. When evaluated independently, clinical scoring systems and ultrasonography have been shown to have low to moderate sensitivity in the diagnosis of appendicitis.

Our study evaluated the accuracy of a clinical practice guideline combining the Samuel’s pediatric appendicitis score and selective ultrasonography as the primary imaging modality for children with suspected appendicitis. Our clinical pathway demonstrated high sensitivity and specificity. (Read the full article)

Left heart defects, such as bicuspid aortic valve, are heritable. Echocardiography screening has been recommended for first-degree relatives of patients with left heart defects. Such screening may allow timely recognition of complications such as progressive aortic dilation.

This study examines the utility and cost of echocardiography screening of siblings of patients with bicuspid aortic valve in clinical practice. Screening has high yield, and the cost compares favorably with those of other screening methods used in pediatrics. (Read the full article)

Conventional invasive pneumococcal disease (IPD) definition using laboratory confirmation lacks sensitivity. Using a vaccine-probe design, the FinIP trial showed that IPD disease burden and vaccine-preventable disease incidence were fourfold higher when a more sensitive outcome, clinically suspected IPD, was used.

Vaccine-preventable disease incidence (ie, absolute reduction due to PCV10 vaccination) during routine vaccination program was threefold with the more sensitive outcome of clinically suspected IPD compared with the conventional IPD definition. This has major implications for cost-effectiveness of PCVs. (Read the full article)

Previous research has described important variability in the medical evaluation of suspected child physical abuse. This variability may contribute to bias and reduce reliability in the medical diagnosis of abuse.

A panel of child abuse pediatricians participated in a Delphi Process, defining critical elements for the medical evaluation of suspected physical abuse in children. Results can be used to reduce practice variability that may contribute to potential bias in evaluation. (Read the full article)

BACKGROUND AND OBJECTIVES:

Antibiotic therapy is often prescribed for suspected community-acquired pneumonia (CAP) in children despite a lack of knowledge of causative pathogen. Our objective in this study was to investigate the association between antibiotic prescription and treatment failure in children with suspected CAP who are discharged from the hospital emergency department (ED).

Matthew J. Lipshaw
Apr 1, 2020; 145:e20193138-e20193138
ARTICLES

The WireGuard protocol is intended to be the future of VPNs, promising better speeds and security. We tested NordVPN's implementation, and WireGuard appears set to deliver on its promises.

The Scottish Parliament has announced it will suspend public engagement activities as it prioritises supporting parliamentary business and responding to the Coronavirus.

Secretary of State Jeffrey Bullock and the state Board of Dentistry and Dental Hygiene have suspended the Delaware dental license of Dr. I-Yin Liu, in light of allegations that she has repeatedly violated standards of professional practice, has been subject to criminal arrest for her conduct, and subsequently violated the terms of her bail.

Secretary of State Jeffrey Bullock and the state Board of Nursing have suspended the Delaware nursing license of Angela M. Gonzalez-Andino, in light of allegations of unprofessional conduct related to the diversion of prescription medications.

Secretary of State Jeffrey Bullock has suspended the Delaware medical license and controlled substance privileges of Gregory Villabona, in light of allegations of unprofessional conduct related to the prescription and distribution of opioid medications.

Secretary of State Jeffrey Bullock has suspended the Delaware chemical dependency counseling license of Sachin Karnik in light of recent criminal charges filed against him.

Secretary of State Jeffrey Bullock has suspended the Delaware medical license and controlled substance prescribing privileges of Ifeanyi Udezulu for repeatedly failing to adhere to state regulations for the safe prescribing of opioid medications.

Secretary of State Jeffrey Bullock has suspended the Delaware massage therapy license of Christopher D. Dorman in light of allegations of sexual assault made by several female clients.

Secretary of State Jeffrey Bullock has suspended the Delaware electrician license of Andrew S. Atkins for engaging in unlawful sexual conduct with a minor.

Four top Republican senators have urged US President Donald Trump to suspend all new guest worker visas for 60 days and some of its categories, including the H-1B visa, for at least the next year or...