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Elton John's 'Me' is what a memoir should be

The long-awaited book is frank, funny, self-lacerating and full of gossip worthy anecdotes. What else could we ask of the Rocketman?






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When movie theatres no longer exist...

Aseem Chhabra imagines a time, 20 years from now, when movie-watching in theatres will be long gone, thanks to the coronavirus, and pens a letter to his grandchild, explaining the magic of the cinema hall.




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Diamond Joe






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Bilberry anthocyanin extracts enhance anti-PD-L1 efficiency by modulating gut microbiota

Food Funct., 2020, 11,3180-3190
DOI: 10.1039/D0FO00255K, Paper
Luoyang Wang, Guoqiang Jiang, Nan Jing, Xuerun Liu, Qicheng Li, Wei Liang, Zheng Liu
Bilberry anthocyanin extracts change the gut microbiota and enhance the anti-tumor efficiency of the PD-L1 antibody.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Vinegar extract ameliorates alcohol-induced liver damage associated with the modulation of gut microbiota in mice

Food Funct., 2020, 11,2898-2909
DOI: 10.1039/C9FO03015H, Paper
Ting Xia, Bo Zhang, Shaopeng Li, Bin Fang, Wenhui Duan, Jin Zhang, Jia Song, Min Wang
Vinegar extract inhibited alcohol-induced ROS generation and inflammation. Vinegar extract modulated gut microbiota and improved intestinal homeostasis, which could be used as a novel gut microbiota manipulator against alcohol-induced liver damage.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Seaweed Porphyra yezoensis polysaccharides with different molecular weights inhibit hydroxyapatite damage and osteoblast differentiation of A7R5 cells

Food Funct., 2020, 11,3393-3409
DOI: 10.1039/C9FO01732A, Paper
Ling-Hong Huang, Hong Liu, Jia-Yun Chen, Xin-Yuan Sun, Zhi-hui Yao, Jin Han, Jian-Ming Ouyang
Porphyra yezoensis polysaccharide could effectively reduce the cell damage and osteogenic transformation of vascular smooth muscle cells induced by hydroxyapatite crystals.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Girinimbine from curry leaves promotes gastro protection against ethanol induced peptic ulcers and improves healing via regulation of anti-inflammatory and antioxidant mechanisms

Food Funct., 2020, 11,3493-3505
DOI: 10.1039/D0FO00053A, Paper
Syam Mohan, Yahya Hasan Hobani, Emad Shaheen, Alaa Sayed Abou-Elhamd, Aymen abdelhaleem, Hassan A. Alhazmi, Siddig Ibrahim Abdelwahab
Curry leaves (Murraya koenigii) are a leafy spice used in Indian cookery for its fragrant aroma.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Purification, characterization and molecular cloning of a dicaffeoylquinic acid-hydrolyzing esterase from human-derived Lactobacillus fermentum LF-12

Food Funct., 2020, 11,3235-3244
DOI: 10.1039/D0FO00029A, Paper
Yujin Liu, Minhao Xie, Peng Wan, Guijie Chen, Chunxu Chen, Dan Chen, Shijie Yu, Xiaoxiong Zeng, Yi Sun
Dicaffeoylquinic acids (DiCQAs), the main components of kudingcha made from the leaves of Ilex kudingcha, could be transformed by gut microbiota.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Integrated anti-hyperlipidemic bioactivity of whole Citrus grandis [L.] osbeck fruits—multi-action mechanism evidenced using animal and cell models

Food Funct., 2020, 11,2978-2996
DOI: 10.1039/C9FO02290B, Paper
Li-Yun Lin, Boa-Chan Huang, Kuan-Chou Chen, Robert Y. Peng
Multi- antihyperlipidemic mechanism revealed by the pomelo phytonutrients. Both the sterol synthesis and lipogenesis pathways are affected by the pomelo phytonutrients. Dotted line: from citation. Solid line: verified in this experiment.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ptaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice

Food Funct., 2020, 11,3298-3305
DOI: 10.1039/D0FO00207K, Paper
Rui M. Gil da Costa, Tiago Neto, Diogo Estêvão, Magda Moutinho, Ana Félix, Rui Medeiros, Carlos Lopes, Margarida M. S. M. Bastos, Paula A. Oliveira
Bracken (Pteridium spp.) is a common weed that is consumed as food especially in Asia, and is suspected of promoting carcinogenesis induced by papillomaviruses in the digestive and urinary systems.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chronic flavanol-rich cocoa powder supplementation reduces body fat mass in endurance athletes by modifying the follistatin/myostatin ratio and leptin levels

Food Funct., 2020, 11,3441-3450
DOI: 10.1039/D0FO00246A, Paper
Jose Ángel García-Merino, Diego Moreno-Pérez, Beatriz de Lucas, Maria Gregoria Montalvo-Lominchar, Elsa Muñoz, Lara Sánchez, Fernando Naclerio, Karen Marlene Herrera-Rocha, Martha Rocío Moreno-Jiménez, Nuria Elisabeth Rocha-Guzmán, Mar Larrosa
Flavanols-rich cocoa reduced body fat composition in athletes through modulation of follistatin and leptin levels.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cloning, expression and comparison of the properties of Scy p 9, a Scylla paramamosain allergen

Food Funct., 2020, 11,3006-3019
DOI: 10.1039/D0FO00004C, Paper
Xin-Rong He, Yi-Meng Cheng, Yang Yang, Jie-Jing Xie, Ka-Hou Chu, Yong-Xia Zhang, Gui-Xia Chen, Hong Liu, Min-Jie Cao, Guang-Ming Liu
This study investigated the properties of Scy p 9 in mud crab (Scylla paramamosain).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Molecular mechanisms of selenium-biofortified soybean protein and polyphenol conjugates in protecting mouse skin damaged by UV-B

Food Funct., 2020, 11,3563-3573
DOI: 10.1039/C9FO02560J, Paper
Xing Zhang, Hui He, Tao Hou
A new selenium-biofortified protein and polyphenol conjugate with high antioxidant activity and stability for the treatment of photooxidation-related diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ergosterol peroxide from Pleurotus ferulae inhibits gastrointestinal tumor cell growth through induction of apoptosis via reactive oxygen species and endoplasmic reticulum stress

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02454A, Paper
Yi Yang, Xiaoyu Luo, Mayila Yasheng, Jun Zhao, Jinyu Li, Jinyao Li
Ergosterol peroxide was purified from Pleurotus ferulae by silica gel chromatography, Sephadex LH-20 chromatography and recrystallization and named as PFEP, which was identified by ESI-MS and NMR.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Kaempferol modulates TCDD- and t-BHQ-induced drug-metabolizing enzymes and luteolin enhances this effect

Food Funct., 2020, 11,3668-3680
DOI: 10.1039/C9FO02951F, Paper
Tomoya Kitakaze, Atsushi Makiyama, Rika Nakai, Yuki Kimura, Hitoshi Ashida
Co-treatment with kaempferol and luteolin inhibits AhR- and Nrf2-induced expression of drug-metabolizing enzymes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and α-glucosidase inhibitory activities

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00342E, Paper
Oscar Galarce-Bustos, Mª Teresa Fernández-Ponce, Antonio Montes, Clara Pereyra, Lourdes Casas, Casimiro Mantell, Mario Aranda
The wastes generated by cherimoya cultivation and processing industries should be contemplated as a valuable source of bioactive alkaloids, with potential in pharmaceutical applications for the treatment or prevention of chronic diseases.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tomato seed oil attenuates hyperlipidemia and modulates gut microbiota in C57BL/6J mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00133C, Paper
Wen-Sen He, Lingling Li, Jiaxin Rui, Junjie Li, Yuying Sun, Dandan Cui, Bin Xu
TSO can significantly improve fatty acid metabolism and cholesterol metabolism, thereby inhibiting obesity and hypercholesterolemia. TSO can favorably modulate the gut microbiota.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO03017D, Paper
Ruiqiu Zhao, Yang Ji, Xin Chen, Anxiang Su, Gaoxing Ma, Guitang Chen, Qiuhui Hu, Liyan Zhao
Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effects of polysaccharides from wild morels on immune response and gut microbiota composition in non-treated and cyclophosphamide-treated mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00597E, Paper
Wenyan Huo, Zhengping Feng, Suying Hu, Langjun Cui, Ting Qiao, Lu Dai, Peng Qi, Liguang Zhang, Yu Liu, Junzhi Li
Polysaccharides from wild morels alter gut microbiota, increase the production of SCFAs and promote the proliferation of lymphocytes in mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00427H, Paper
Xiao-Shan Long, Sen-Tai Liao, Peng Wen, Yu-Xiao Zou, Fan Liu, Wei-Zhi Shen, Teng-Gen Hu
Mulberry removed monosaccharides (FM) displayed better hypoglycemic activity than untreated mulberry (MP), which may be attributed the stronger effects of FM on activating PI3K/Akt and AMPK signaling pathways.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Structural and physicochemical changes in almond milk during in vitro gastric digestion: impact on the delivery of protein and lipids

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02465D, Paper
Xin Wang, Aiqian Ye, Harjinder Singh
The gastric digestion of almond milk in a human gastric simulator resulted in major structural and physicochemical changes. The changes had significant impact on the rate of delivery of protein and lipids to the small intestine.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Lactic acid bacteria alleviates polycystic ovarian syndrome by regulating sex hormone related gut microbiota

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02554E, Paper
Yufeng He, Qianqian Wang, Xiu Li, Gang Wang, Jianxin Zhao, Hao Zhang, Wei Chen
Polycystic ovarian syndrome (PCOS) is a common endocrine disease across the world. Because gut microbiota play a key role in the pathogenesis of PCOS, probiotics may alleviate PCOS symptoms through...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The effect of quercetin on endothelial cells is modified by heterocellular interactions

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00141D, Paper
Open Access
Sarka Tumova, Michael J. Houghton, Gary Williamson
Single cell-type models are useful for determining mechanisms, but in vivo, cell–cell interactions are important, and neighbouring cells can impact endothelial cell function.
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The cognitive effects of an acute wild blueberry intervention on 7 – 10 year olds using extended memory and executive function task batteries.

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02284H, Paper
Adrian Robert Whyte, Daniel J Lamport, Graham Schafer, Claire M. Williams
Evidence for the health benefits of blueberries is well documented. In particular memory and executive function benefits have both been found for children aged 7 – 10 in the 6...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Sugar matters: sugar moieties as reactivity-tuning factors in quercetin O-glycosides

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00319K, Paper
Cezara Zagrean-Tuza, Augustin C Moţ, Tomasz Chmiel, Attila Bende, Ioan Turcu
Quercetin, one of the most abundant flavonoids in plant-based foods, commonly occurs in nature in various glycosylated forms. There is still a less explored aspect regarding the cause of its...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lactobacillus fermentum CECT5716 prevents renal damage in NZBWF1 mice model of systemic lupus erythematosus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00578A, Paper
Néstor de la Visitación, Iñaki Robles-Vera, Marta Toral, Francisco O’Valle, Javier Moleon, Manuel Gómez-Guzmán, Miguel Romero, Marcos Duarte, Manuel Sanchez, Rosario Jimenez, Juan Duarte
The aim of this work was to evaluate whether the immune-modulatory bacteria Lactobacillus fermentum CECT5716 (LC40) protects kidneys in a female mouse model of lupus with hypertension. Twenty-week-old NZBWF1 (lupus)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hypoglycemic effects and modulation of gut microbiota of diabetic mice by saponin from Polygonatum sibiricum

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00428F, Paper
Jiayuan Luo, Yangyang Chai, Min Zhao, Qingqi Guo, Yihong Bao
Polygonatum sibiricum is a medicinal and homologous plant grown in China. The saponin in Polygonatum sibiricum has shown its good hypoglycemic performance, and it can be developed as functional foods and drugs with hypoglycemic effect.
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Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02602A, Paper
Chu-Wen Li, Min-Zhen Deng, Zhi-Jie Gao, Yuan-Ye Dang, Guo-Dong Zheng, Xiu-Juan Yang, Ying-Xin Chao, Ye-Feng Cai, Xiao-Li Wu
The metabolite of ginsenosides, compound K improves memory and cognitive dysfunction in diabetes mellitus mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Evaluation of Tenebrio molitor protein as a source of peptides for modulating physiological processes

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00734J, Paper
Fernando Rivero Pino, Raúl Pérez Gálvez, F. Javier Espejo Carpio, Emilia M. Guadix
Tenebrio molitor hydrolysates produced with commercial proteases showed improved ACE inhibitory and antioxidant properties. This source could be employed as functional ingredient in food preparations.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Influences of dietary starch structure on intestinal morphology, barrier functions, and epithelium apoptosis in weaned pigs

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02652E, Paper
Open Access
Xiaoqian Gao, Bing Yu, Jie Yu, Xiangbing Mao, Zhiqing Huang, Yuheng Luo, Junqiu Luo, Ping Zheng, Jun He, Daiwen Chen
The objective of the present study was to evaluate the effects of dietary starch structure on intestinal health of weaned pigs by determining the intestinal morphology, barrier functions, epithelium apoptosis and digestive enzymes.
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Deciphering calcium-binding behaviors of casein phosphopeptides by experimental approaches and molecular simulation

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00844C, Paper
Minna Luo, Jie Xiao, Shengwei Sun, Fengchao Cui, Wei Li, Guo Liu, Yunqi Li, Yong Cao
Although specific groups in casein phosphopeptides (CPPs) have been identified to be essential for the calcium-binding capacity, how calcium binds with CPPs remains unclear. In the present study, experimental methods...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The milk macromolecular peptide: preparation and evaluation of antihypertensive activity in rats

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00151A, Paper
Pengfei Cui, Xue Yang, Yunliang Li, Qiufang Liang, Yucheng Wang, Feng Lu, John Owusu, Shanfen Huang, Xiaofeng Ren, Haile Ma
In order to avoid the discomfort of digesting milk protein and make full use of the gastrointestinal digestive function, a milk macromolecular peptide was prepared with ACE inhibitory activity after gastrointestinal digestion as the index.
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Pterostilbene prevents LPS-induced early pulmonary fibrosis by suppressing oxidative stress, inflammation and apoptosis in vivo

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02521A, Paper
Huahong Yang, Cong Hua, Xiaolin Yang, Xiaoye Fan, Hongyu Song, Liping Peng, Xinxin Ci
Schematic model of the protective effects by Pts on LPS-induced lung fibrosis.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Polysaccharides from Enteromorpha prolifera protect against carbon tetrachloride-induced acute liver injury in mice via activation of Nrf2/HO-1 signaling, and suppression of oxidative stress, inflammation and apoptosis

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00575D, Paper
Fuchuan Guo, Xinyun Zhuang, Mengyuan Han, Wenting Lin
EPP protected against hepatic injury induced by CCl4-derived reactive intermediates through the suppression of hepatic oxidative stress, inflammation, and apoptosis.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Unsaturated alginate oligosaccharides attenuated obesity-related metabolic abnormalities by modulating gut microbiota in high-fat-diet mice

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02857A, Paper
Shangyong Li, Linna Wang, Bo Liu, Ningning He
Gut microbiota plays an important role in the high-fat diet (HFD)-induced obesity and related metabolic syndrome (MetS). Our previous study has demonstrated that unsaturated alginate oligosaccharides (UAOS) degraded by alginate...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Adjunctive vitamin A and D during pulmonary tuberculosis treatment: a randomized controlled trial with a 2×2 factorial design

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02751C, Paper
Jinyu Wang, Ke Xiong, Qiuzhen Wang, Shanliang Zhao, Yufeng Liu, Aiguo Ma
Background and objective: Vitamin A and D have immunoregulatory effects and may improve the response to pulmonary tuberculosis treatment. The interaction of vitamin A and D on pulmonary tuberculosis treatment...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pausing SIP set to become simpler; more fund houses to offer option

Many fund houses don't yet offer the pause facility but are scrambling to put one in place for investors




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With 30 days more to pay premium, make sure you don't let your policy lapse

Usually, general insurers give 30 days for health and 90 days for auto insurance policyholders to pay renewal premiums, even after the due date has passed




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Lockdown 2.0: Govt extends renewal of health, motor policies till May 15

If the renewal of motor third party and health policy falls due between March 25 and May 3, the lockdown period, then policyholders can make the renewal payment on or before May 15




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Motor, health segments see substantial fall in March for non-life insurers

Motor segment saw a 7 per cent decline in premiums, while health registered an 11 per cent decline in premiums




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16% landlords drop 2 months' rent, 44% didn't raise it in pandemic: Survey

The survey, conducted by property classified 99acres.com which is owned by Info Edge India Ltd, polled 49,600 house owners and brokers who have listed properties for rent or sale




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Apple Introduces watchOS 2 with Native Apps and New Apple Watch Sport Models

Apple has introduced new Apple Watch cases and bands, available starting today, including new gold and rose gold aluminum Apple Watch Sport models. watchOS 2 — which arrives as a free update on September 16 — makes apps faster and more fluid by running natively on Apple Watch, and introduces new watch faces, the ability for third-party apps to display information on the watch face as complications, and an innovative way to see future events, past headlines, and more with Time Travel. Apple Watch collections are expanding with new case colors and fresh new bands. With new standalone Sport Bands that range from rich vibrant colors to more neutral tones, Apple Watch is now more customizable than ever.




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OS X El Capitan Available as Free Update Tomorrow

OS X El Capitan, the latest major release of the world’s most advanced desktop operating system, will be available Wednesday, September 30, as a free update for Mac users. El Capitan builds on the groundbreaking features and beautiful design of OS X Yosemite. “People love using their Macs, and one of the biggest reasons is the power and ease of use of OS X,” said Craig Federighi, Apple’s senior vice president of Software Engineering. “El Capitan refines the Mac experience and improves performance in a lot of little ways that make a very big difference. Feedback from our OS X beta program has been incredibly positive and we think customers are going to love their Macs even more with El Capitan.”




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Apple Introduces iPhone SE — the Most Powerful Phone with a 4-inch Display

Apple today introduced iPhone SE, the most powerful phone with a 4-inch display, in a compact aluminum design that has been updated with matte-chamfered edges, a color-matched stainless steel Apple logo, and four metallic finishes. iPhone SE offers the same 64-bit A9 chip offered in iPhone 6s and iPhone 6s. “iPhone SE is packed with a stunning 4-inch Retina display, advanced 64-bit A9 chip with M9 motion co-processor, longer battery life, 12-megapixel iSight camera with True Tone flash, Live Photos, 4K video, faster LTE and Wi-Fi, and Touch ID with Apple Pay. Everyone who wants a smaller phone is going to love iPhone SE,” said Philip Schiller, Apple’s senior vice president of Worldwide Marketing.