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[ASAP] Astragalin Exerted Antidepressant-like Action through SIRT1 Signaling Modulated NLRP3 Inflammasome Deactivation

ACS Chemical Neuroscience
DOI: 10.1021/acschemneuro.0c00156




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Commodity outlook and recommendation by Tradebulls Sec: Buy Gold, Copper

The crude oil situation has made investors running for cash and dumping commodities




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Average mandi prices of most agri commodities show mixed trend in April

A disruption in supply chain means that the arrival of commodities across the nation's main mandis remained a cause of concern




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Commodity picks: 4 May, 2020

For the month ahead mustard prices are expected to head towards Rs 4,400




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[ASAP] A Fluorescence and Surface-Enhanced Raman Spectroscopic Dual-Modal Aptasensor for Sensitive Detection of Cyanotoxins

ACS Sensors
DOI: 10.1021/acssensors.0c00307




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[ASAP] Revealing the Photodynamic Stress <italic toggle="yes">In Situ</italic> with a Dual-Mode Two-Photon <sup>1</sup>O<sub>2</sub> Fluorescent Probe

ACS Sensors
DOI: 10.1021/acssensors.0c00303




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The handbook of education and human development: new models of learning, teaching, and schooling / edited by David R. Olson and Nancy Torrance

Online Resource




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Mathematical modelling in education research and practice: cultural, social and cognitive influences / Gloria Ann Stillman, Werner Blum, Maria Salett Biembengut, editors

Online Resource




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Organizing Enlightenment: information overload and the invention of the modern research university / Chad Wellmon

Hayden Library - LA727.W45 2015




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Hospitality stakeholders differ on returnees’ accommodation

Operators of high-end properties fear damage to rooms and premium furnishings




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A new lithium diffusion model in layered oxides based on asymmetric but reversible transition metal migration

Energy Environ. Sci., 2020, 13,1269-1278
DOI: 10.1039/C9EE04123K, Paper
Kyojin Ku, Byunghoon Kim, Sung-Kyun Jung, Yue Gong, Donggun Eum, Gabin Yoon, Kyu-Young Park, Jihyun Hong, Sung-Pyo Cho, Do-Hoon Kim, Hyungsub Kim, Eunsuk Jeong, Lin Gu, Kisuk Kang
We propose a new lithium diffusion model involving coupled lithium and transition metal migration, peculiarly occurring in a lithium-rich layered oxide.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Unveiling the Mechanisms of Lithium Dendrite Suppression by Cationic Polymer Film Induced Solid-Electrolyte Interphase Modification

Energy Environ. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0EE00518E, Paper
Seung-Yong Lee, Junyi Shangguan, Judith Alvarado, Sophia Betzler, Stephen J Harris, Marca Doeff, Haimei Zheng
It is crucial to suppress lithium dendrite formation in lithium metal batteries. Formation of good solid-electrolyte interphase (SEI) has been considered to be effective in limiting lithium dendrite growth. However,...
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] Co(salen)-Catalyzed Oxidation of Lignin Models to Form Benzoquinones and Benzaldehydes: A Computational and Experimental Study

ACS Sustainable Chemistry & Engineering
DOI: 10.1021/acssuschemeng.0c01970




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[ASAP] Product Modification in Catalytic Fast Pyrolysis of Corn Stalk: The Decoupled Effect of Acidity and Porosity within a Core–Shell Micro-/Mesoporous Zeolite

ACS Sustainable Chemistry & Engineering
DOI: 10.1021/acssuschemeng.0c01518




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[ASAP] Chemistry and Spectroscopy of Renewable Materials, Part 2: Investigation of Suitably Esterified Wood Regarding Penetration and Distribution of the Chemically Modifying Reagent by Means of High-Resolution 3D Computed Tomography

ACS Sustainable Chemistry & Engineering
DOI: 10.1021/acssuschemeng.0c01574




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Development of sustainable bioprocesses : modeling and assessment / Elmar Heinzle, Arno P. Biwer, Charles L. Cooney

Heinzle, Elmar




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Modern biotechnology : connecting innovations in microbiology and biochemistry to engineering fundamentals / Nathan S. Mosier, Michael R. Ladisch

Mosier, Nathan S




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Animal biotechnology : models in discovery and translation / edited by Ashish S. Verma, Anchal Singh




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Computational fluid dynamics (CFD) and reaction modelling study of bio-oil catalytic hydrodeoxygenation in microreactors

React. Chem. Eng., 2020, Advance Article
DOI: 10.1039/D0RE00102C, Paper
Sanaa Hafeez, Elsa Aristodemou, George Manos, S. M. Al-Salem, Achilleas Constantinou
A computational fluid dynamics (CFD) model was derived and validated in order to investigate the hydrodeoxygenation reaction of 4-propylguaiacol, which is a lignin-derived compound present in bio-oil.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Elementary reaction pathway study and a deduced macrokinetic model for the unified understanding of Ni-catalyzed steam methane reforming

React. Chem. Eng., 2020, 5,873-885
DOI: 10.1039/C9RE00460B, Paper
Changming Ke, Zijing Lin
DFT based microkinetics and macrokinetics that give quantitative explanations of the Ni-catalyzed steam methane reforming reactions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Plasma-enhanced catalysis for the upgrading of methane: a review of modelling and simulation methods

React. Chem. Eng., 2020, 5,814-837
DOI: 10.1039/D0RE00024H, Review Article
Pierre-André Maitre, Matthew S. Bieniek, Panagiotis N. Kechagiopoulos
Modelling methods and simulation works on the upgrading of methane via plasma and plasma-enhanced catalysis reviewed.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Optimization of the direct synthesis of dimethyl ether from CO2 rich synthesis gas: closing the loop between experimental investigations and model-based reactor design

React. Chem. Eng., 2020, 5,949-960
DOI: 10.1039/D0RE00041H, Paper
Open Access
Nirvana Delgado Otalvaro, Markus Kaiser, Karla Herrera Delgado, Stefan Wild, Jörg Sauer, Hannsjörg Freund
Kinetic modeling, model-based optimization and experimental validation for the direct DME synthesis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] Ultrasmall Gold Nanoparticles Coated with Zwitterionic Glutathione Monoethyl Ester: A Model Platform for the Incorporation of Functional Peptides

The Journal of Physical Chemistry B
DOI: 10.1021/acs.jpcb.0c01444




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[ASAP] Thermodynamic and Kinetic Studies of the Radical Scavenging Behavior of Hydralazine and Dihydralazine: Theoretical Insights

The Journal of Physical Chemistry B
DOI: 10.1021/acs.jpcb.0c02439




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[ASAP] Molecular Recognition between Cadherins Studied by a Coarse-Grained Model Interacting with a Coevolutionary Potential

The Journal of Physical Chemistry B
DOI: 10.1021/acs.jpcb.0c01671




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[ASAP] Targeted Delivery of Adamantylated Peptidoglycan Immunomodulators in Lipid Nanocarriers: NMR Shows That Cargo Fragments Are Available on the Surface

The Journal of Physical Chemistry B
DOI: 10.1021/acs.jpcb.0c00029




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Naidu, Modi pay tributes to Maharana Pratap

On Mewar king’s 480th birth anniverary, the Prime Minister described him as the great son of Mother India.




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Tamil Nadu Chief Minister urges Prime Minister Modi to place amendments to Electricity Act in abeyance

In a letter to the Prime Minister, Edappadi K. Palaniswami reiterated that Tamil Nadu was committed to providing free electricity supply to farmers, and said the Bill could affect this policy




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Asset Liability Management Optimisation: A Practitioner's Guide to Balance Sheet Management and Remodelling


 

An advanced method for financial institutions to optimize Asset Liability Management for maximized return and minimized risk

Financial institutions today are facing daunting regulatory and economic challenges. As they manage bank regulation and competition, institutions are also optimizing their Asset Liability Management (ALM) operations. The function of the ALM unit today goes beyond risk management related to the banking book into managing regulatory



Read More...




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Being a woman in Modi's world of men

What is it like to be a woman in a male-dominated profession like a police officer, asks Adrija Shukla.




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Bilberry anthocyanin extracts enhance anti-PD-L1 efficiency by modulating gut microbiota

Food Funct., 2020, 11,3180-3190
DOI: 10.1039/D0FO00255K, Paper
Luoyang Wang, Guoqiang Jiang, Nan Jing, Xuerun Liu, Qicheng Li, Wei Liang, Zheng Liu
Bilberry anthocyanin extracts change the gut microbiota and enhance the anti-tumor efficiency of the PD-L1 antibody.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Vinegar extract ameliorates alcohol-induced liver damage associated with the modulation of gut microbiota in mice

Food Funct., 2020, 11,2898-2909
DOI: 10.1039/C9FO03015H, Paper
Ting Xia, Bo Zhang, Shaopeng Li, Bin Fang, Wenhui Duan, Jin Zhang, Jia Song, Min Wang
Vinegar extract inhibited alcohol-induced ROS generation and inflammation. Vinegar extract modulated gut microbiota and improved intestinal homeostasis, which could be used as a novel gut microbiota manipulator against alcohol-induced liver damage.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Integrated anti-hyperlipidemic bioactivity of whole Citrus grandis [L.] osbeck fruits—multi-action mechanism evidenced using animal and cell models

Food Funct., 2020, 11,2978-2996
DOI: 10.1039/C9FO02290B, Paper
Li-Yun Lin, Boa-Chan Huang, Kuan-Chou Chen, Robert Y. Peng
Multi- antihyperlipidemic mechanism revealed by the pomelo phytonutrients. Both the sterol synthesis and lipogenesis pathways are affected by the pomelo phytonutrients. Dotted line: from citation. Solid line: verified in this experiment.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chronic flavanol-rich cocoa powder supplementation reduces body fat mass in endurance athletes by modifying the follistatin/myostatin ratio and leptin levels

Food Funct., 2020, 11,3441-3450
DOI: 10.1039/D0FO00246A, Paper
Jose Ángel García-Merino, Diego Moreno-Pérez, Beatriz de Lucas, Maria Gregoria Montalvo-Lominchar, Elsa Muñoz, Lara Sánchez, Fernando Naclerio, Karen Marlene Herrera-Rocha, Martha Rocío Moreno-Jiménez, Nuria Elisabeth Rocha-Guzmán, Mar Larrosa
Flavanols-rich cocoa reduced body fat composition in athletes through modulation of follistatin and leptin levels.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Kaempferol modulates TCDD- and t-BHQ-induced drug-metabolizing enzymes and luteolin enhances this effect

Food Funct., 2020, 11,3668-3680
DOI: 10.1039/C9FO02951F, Paper
Tomoya Kitakaze, Atsushi Makiyama, Rika Nakai, Yuki Kimura, Hitoshi Ashida
Co-treatment with kaempferol and luteolin inhibits AhR- and Nrf2-induced expression of drug-metabolizing enzymes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tomato seed oil attenuates hyperlipidemia and modulates gut microbiota in C57BL/6J mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00133C, Paper
Wen-Sen He, Lingling Li, Jiaxin Rui, Junjie Li, Yuying Sun, Dandan Cui, Bin Xu
TSO can significantly improve fatty acid metabolism and cholesterol metabolism, thereby inhibiting obesity and hypercholesterolemia. TSO can favorably modulate the gut microbiota.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO03017D, Paper
Ruiqiu Zhao, Yang Ji, Xin Chen, Anxiang Su, Gaoxing Ma, Guitang Chen, Qiuhui Hu, Liyan Zhao
Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The effect of quercetin on endothelial cells is modified by heterocellular interactions

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00141D, Paper
Open Access
Sarka Tumova, Michael J. Houghton, Gary Williamson
Single cell-type models are useful for determining mechanisms, but in vivo, cell–cell interactions are important, and neighbouring cells can impact endothelial cell function.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lactobacillus fermentum CECT5716 prevents renal damage in NZBWF1 mice model of systemic lupus erythematosus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00578A, Paper
Néstor de la Visitación, Iñaki Robles-Vera, Marta Toral, Francisco O’Valle, Javier Moleon, Manuel Gómez-Guzmán, Miguel Romero, Marcos Duarte, Manuel Sanchez, Rosario Jimenez, Juan Duarte
The aim of this work was to evaluate whether the immune-modulatory bacteria Lactobacillus fermentum CECT5716 (LC40) protects kidneys in a female mouse model of lupus with hypertension. Twenty-week-old NZBWF1 (lupus)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hypoglycemic effects and modulation of gut microbiota of diabetic mice by saponin from Polygonatum sibiricum

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00428F, Paper
Jiayuan Luo, Yangyang Chai, Min Zhao, Qingqi Guo, Yihong Bao
Polygonatum sibiricum is a medicinal and homologous plant grown in China. The saponin in Polygonatum sibiricum has shown its good hypoglycemic performance, and it can be developed as functional foods and drugs with hypoglycemic effect.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Evaluation of Tenebrio molitor protein as a source of peptides for modulating physiological processes

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00734J, Paper
Fernando Rivero Pino, Raúl Pérez Gálvez, F. Javier Espejo Carpio, Emilia M. Guadix
Tenebrio molitor hydrolysates produced with commercial proteases showed improved ACE inhibitory and antioxidant properties. This source could be employed as functional ingredient in food preparations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Unsaturated alginate oligosaccharides attenuated obesity-related metabolic abnormalities by modulating gut microbiota in high-fat-diet mice

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02857A, Paper
Shangyong Li, Linna Wang, Bo Liu, Ningning He
Gut microbiota plays an important role in the high-fat diet (HFD)-induced obesity and related metabolic syndrome (MetS). Our previous study has demonstrated that unsaturated alginate oligosaccharides (UAOS) degraded by alginate...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Apple Introduces watchOS 2 with Native Apps and New Apple Watch Sport Models

Apple has introduced new Apple Watch cases and bands, available starting today, including new gold and rose gold aluminum Apple Watch Sport models. watchOS 2 — which arrives as a free update on September 16 — makes apps faster and more fluid by running natively on Apple Watch, and introduces new watch faces, the ability for third-party apps to display information on the watch face as complications, and an innovative way to see future events, past headlines, and more with Time Travel. Apple Watch collections are expanding with new case colors and fresh new bands. With new standalone Sport Bands that range from rich vibrant colors to more neutral tones, Apple Watch is now more customizable than ever.




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A visit from Modi to Israel will be important: Daniel Carmon

Interview with ambassador of Israel to India




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When to send an investing model into retirement

For a model to retain currency it must include new, emerging risk factors




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Tamil Nadu CM writes PM Modi, says Electricity Amendment Bill is against interest of states

Tamil Nadu CM writes PM Modi, says Electricity Amendment Bill is against interest of states




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[ASAP] Inhibitory Effect of Cannabidiol on the Activation of NLRP3 Inflammasome Is Associated with Its Modulation of the P2X7 Receptor in Human Monocytes

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00138




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Highlight.js 10, Node 14, and modern React in 20 minutes

#485 — April 24, 2020

Unsubscribe  :  Read on the Web

JavaScript Weekly

Introducing Crank.js: A New JSX-Driven Framework — A new framework for creating JSX-driven components with functions, promises and generators. If you haven’t got time to read the creator’s lengthy (but well worth reading!) rationale for creating another framework, check out the GitHub repo or jump straight into a CodeSandbox example. I hope to see a lot more about this in the near future.

Brian Kim

The Cost of JavaScript Frameworks — Using data from the HTTP Archive, Tim explores the performance cost of using various popular frameworks as a starting point. Some good analysis here.

Tim Kadlec

You Hacked the Gibson? Yeah, They Built Their Own Login — Don't let Crash Override pwn your app. FusionAuth adds secure login, registration and user management to your app in minutes not months. Download our community edition for free.

FusionAuth sponsor

Node.js 14 Released — v14 now becomes the current ‘release’ line with it becoming a LTS (Long Term Support) release in October. Diagnostic reports are now a stable feature, it now uses V8 8.1, there's an experimental Async Local Storage API, and more.

Michael Dawson and Bethany Griggs

Vidact: A Compiler to Convert React-like Apps to Vanilla JS — Compiles pure React-compatible JavaScript (JSX) to vanilla JavaScript with no virtual DOM.. think similar to Svelte, but without introducing a new syntax. A curious idea.

Mohamad Mohebifar

Highlight.js 10.0: The Web Syntax Highlighter Library — I always laugh when I see a big release of a popular library and saw we last linked it 5 years ago ???? Nonetheless, this is a big release and Highlight.js continues to be a fantastic library for syntax highlighting code.

highlight.js

???? Jobs

Senior Full-stack Developer (Malmö/Sweden) — Every day is different from the next. Join our upbeat Team and work on exciting, major projects using a modern JavaScript stack.

Ortelius AB

Find a Job Through Vettery — Vettery specializes in tech roles and is completely free for job seekers. Create a profile to get started.

Vettery

???? Tutorials

▶  React: The Basics in 20 Minutes — A well presented, up to date (yep, it covers hooks) tutorial that doesn’t hang around, whether you’re new to React or just want a refresher.

Devistry

Creating Web Apps via TypeScript and webpack — The example app doesn’t use any front-end framework, just vanilla DOM APIs. Some knowledge of TypeScript, webpack, and npm are required, but this is a neat way to bring together a bunch of tools.

Axel Rauschmayer

What Is The toJSON() Function? — If an object has a toJSON function, JSON.stringify() calls toJSON() and serializes the return value from toJSON() instead.

Valeri Karpov

A Much Faster Way to Debug Code Than with Breakpoints or console.log — Move forward and backwards through your code to understand what led to a specific bug, view runtime values, edit-and-continue, and more.

Wallaby.js sponsor

How Does TypeScript Work? A Bird’s Eye View — Dr. Axel goes into depth on the structure of a typical TypeScript project, what gets compiled, and how can an IDE be used to write TypeScript. Aimed at people who haven’t yet picked TypeScript up.

Axel Rauschmayer

10 Lesser Known Angular Features You've Probably Never Used

W3Radar

You Might Not Need switch — Using an object of outcomes instead of switch suits many use cases, though take care over readability.

Valentino Gagliardi

???? Upcoming Online Events

  • Pick JS (May 8) — Aimed at intermediate to expert JS developers rather than beginners.
  • JavaScript Remote Conf 2020 (May 14-15) — Speakers lined up already include Douglas Crockford, Aimee Knight and Christian Heilmann.
  • ESNEXT CONF 2020 (May 18-22) — From the Pika folks (of Snowpack fame). 12 speakers over 5 days so it's a gradual pace.
  • ForwardJS (May 26-29) — A real world event (ForwardJS Ottawa) that has now become a virtual event.
  • CascadiaJS 2020 (September 1-2) — This upcoming online conference is set to take place in September, and the CFP is open now through May 15.

???? Code & Tools

Phelia: A Reactive Slack Application Framework — If you think Slack apps were all about text bots, think again.. you can now create apps complete with in-app UIs. Phelia brings the React approach to the task.

Max Chehab

Marked.js 1.0: A Fast Markdown Parser and Compiler — Got Markdown to render? Marked.js to the rescue. While the project is years old, 1.0 has dropped just this week. Here’s a live demo.

Christopher Jeffrey

Stream Chat API & JavaScript SDK for Custom Chat Apps — Build real-time chat in less time. Rapidly ship in-app messaging with our highly reliable chat infrastructure.

Stream sponsor

Alpine.js: A Minimal Framework for Composing JS Behavior in Your Markup — We only gave Alpine a brief link when it first dropped but with new versions coming out thick and fast, we think it’s well worth a look. Billed as “like Tailwind for JavaScript”, Alpine lets you keep the HTML you know and love and just pepper it with JavaScript as and where appropriate.

Alpine.js

enroute: A React Router with a Small Footprint for Modern Browsers

TJ Holowaychuk

Rosetta: A General Purpose Internationalization Library in 292 Bytes — Less than 300 bytes, but does have a few dependencies. Aims to be very simple and is targeted at basic string use cases.

Luke Edwards

NAB 2020 May Be Canceled, But The Full Bitmovin Experience Is Not

Bitmovin Inc. sponsor

Hotkey 1.4: Trigger an Action on an Element When a 'Hotkey' is Pressed — Use Hotkey, set the data-hotkey attribute on your elements, and you get keyboard shortcuts. GitHub built and uses it (look for the data-hotkey attributes on their pages).

GitHub

web-worker: Consistent Web Workers for the Browser and Node — In Node it works as a web-compatible Worker implementation atop worker_threads. In the browser it’s an alias for Worker.

Jason Miller




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Substituted Interests and Best Judgments: An Integrated Model of Surrogate Decision Making

Interview with Daniel P. Sulmasy, MD, PhD, author of Substituted Interests and Best Judgments: An Integrated Model of Surrogate Decision Making