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New 4-year deal 'felt right' for Nola

Aaron Nola established himself as one of the best pitchers in baseball in 2018. The Phillies ensured on Wednesday that he will be the ace in their rotation for possibly the next five seasons.




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Manny? Harper? Klentak satisfied but monitoring

General Manager Matt Klentak discussed the Phillies' offseason in a press conference on Thursday in Clearwater, Fla. The Phillies remain in contact with the agents for Bryce Harper and Manny Machado. The belief is that the front office still prefers Machado over Harper because of Machado's combination of offense and defense.




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Arrieta reveals knee injury led to 2nd-half dip

Jake Arrieta on Thursday offered an unexpected explanation for his second-half struggles in 2018: he pitched much of last season with an injured left knee.




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MacPhail: Phils are 'uniquely poised right now'

Phillies president Andy MacPhail opened a 28-minute press conference on Friday afternoon at Spectrum Field with facts and figures about investments the organization made the past few seasons as the team wallowed at the bottom of the National League. Then MacPhail talked a lot about Bryce Harper and Manny Machado as well as manager Gabe Kapler.




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Franco ignoring rumors, ready for 3B battle

Maikel Franco followed the endless and often mind-numbing speculation the past few months from the Dominican Republic. Franco knows that Manny Machado could show up at Spectrum Field at any moment. The Phillies entertained him at Citizens Bank Park just before Christmas. They have made him at least one contract offer. If the Phillies sign him, Franco also knows he could be traded.




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Talks 'intensifying' between Harper, Phillies

The Phillies have been the favorites in the Bryce Harper sweepstakes for months, and that speculation heated up over the weekend.




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Hernandez healthy, ready to run atop lineup

Cesar Hernandez scored 91 runs last season, the Phillies' highest mark since Rollins scored 102 in 2012. Now the luster is no longer there for players who score 100 runs or post 100 RBIs, but Hernandez should score at least 100 runs this season, if he stays healthy and if the Phillies' offense improves as expected.




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Hoskins would love to play alongside Harper

Will Rhys Hoskins be bummed if Bryce Harper signs elsewhere?




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With Manny off market, Phils' focus on Harper

Bryce Harper is the final superstar standing for the Phillies.




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Get ready to watch: MLB.TV available for 2019

Spring Training is imminent, Opening Day is within sight and the big league season isn't complete for fans without a subscription to MLB.TV. The most comprehensive streaming service in professional sports is now available for the 2019 season.




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Around the Horn: Angels eye improved bullpen

Leading up to the start of Spring Training, the Around the Horn series will examine each of the Angels' positional groupings heading into the 2019 season. Here's a look at the bullpen.




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These are MLB's 10 best position player duos

MLB.com looked at each team's two highest-ranked position players in WAR, according to the Steamer projections. Here are the top 10, but keep in mind that things could change once Manny Machado and Bryce Harper find homes.




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Here's your guide to Angels Spring Training

It's almost time for Spring Training yet again, as Angels pitchers and catchers report to their Spring Training complex in Tempe, Ariz. on Feb. 12.




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Uniform patch to mark 150 years of pro baseball

All 30 Major League teams will wear special "MLB 150" patches on their uniforms for the entire 2019 season in honor of the 150th anniversary of the 1869 Cincinnati Red Stockings, the first openly all-salaried professional baseball team.




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Angels' hope: Ohtani returns as DH in May

Brad Ausmus held his first media session of the spring on the day pitchers and catchers officially reported on Tuesday, giving updates on rehabbing players such as Shohei Ohtani, Albert Pujols and Zack Cozart.




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30 low-key acquisitions who could pay off big

Fans and analysts spend the entire offseason speculating where the top free agents could go, but sometimes an under-the-radar pickup can end up making a world of difference. As positional competitions begin to heat up at Spring Training camps this month, MLB.com's beat writers were asked to identify one potentially overlooked acquisition for each of the 30 clubs. Here's who they came up with.




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Predicting the Angels' Opening Day roster

The Angels head to Spring Training with most of their roster set, but there will be competition for a few spots. Here's a look at the projected roster for the Angels, as they begin their first campaign under manager Brad Ausmus.




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Ohtani upbeat about Tommy John rehab

Shohei Ohtani, who is aiming for a return in May as a designated hitter but won't pitch in 2019, isn't able to participate in the on-field workouts with his teammates, but has progressed to swinging the bat and working out indoors.




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Harvey strains glute, out for a week and a half

Right-hander Matt Harvey sustained a glute strain while participating in agility drills on Wednesday and will be out for roughly a week and a half, Angels manager Brad Ausmus said Thursday.




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The next Ohtani? Walsh to get two-way shot

After Ohtani's nearly unprecedented two-way success during his American League Rookie of the Year campaign last year, more clubs are looking into the possibility of having players who can both pitch and play a position. Walsh fits that bill, as he has been a power-hitting first baseman and outfielder in the Minors, but he's made 10 pitching appearances over the past three seasons as well. The Angels are experimenting with him doing both this spring and this upcoming season.




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Healthy Cozart eyes bounce-back season

After undergoing surgery in late June to repair a torn left labrum in his left shoulder that required nine anchors to be inserted to keep everything in place, Zack Cozart is healthy and looking for a bounce-back season with the Angels.




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Pujols healthy, aims to be ready Opening Day

Angels first baseman Albert Pujols met with the media for the first time this spring on Sunday and said he's fully healthy after undergoing arthroscopic surgery on his left knee in late August.




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Upton out with tendinitis; Harvey starts to throw

The Angels will be without left fielder Justin Upton early in Spring Training, as he's dealing with right knee patellar tendinitis but is expected to be ready for Opening Day, manager Brad Ausmus said on Monday.




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Angels, Lucroy ready to make adjustments

The Angels believe they can help newly acquired catcher Jonathan Lucroy improve both offensively and defensively.




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HIV: Breakthrough study raises hopes of effective prevention if drug’s cost can be lowered




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Test for syphilis in people with possible symptoms, says UKHSA, as cases rise




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Condom use in adolescents has fallen notably since 2014, warns WHO




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First mpox vaccines arrive in Africa as officials work “blindly” to contain outbreaks




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Whooping cough: Why have vaccination rates plummeted in pregnant women?




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Why are doctors being warned about the Oropouche virus?




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Leprosy: Jordan becomes first country to eliminate disease




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Covid inquiry: UKHSA chief is challenged on view that evidence for FFP3 masks is “weak”




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Boy who survived life support withdrawal confirms “medicine is a science of uncertainty,” says judge




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Politicians are failing to prepare for next pandemic, warns head of European health agency




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Targeted TB screening could help halt rise in cases, says Public Health Scotland




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Correction: Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. [Additions and Corrections]

VOLUME 279 (2004) PAGES 33438–33446For Fig. 1B, the second, third, and fifth panels were mistakenly duplicated during article preparation as no yeast colonies were observed in these conditions. The corrected images are presented in the revised Fig. 1B. This correction does not affect the results or conclusions of the work. The authors apologize for the error.jbc;295/50/17382/F1F1F1Figure 1B.




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Correction: Transcriptional factors Smad1 and Smad9 act redundantly to mediate zebrafish ventral specification downstream of Smad5. [Additions and Corrections]

VOLUME 289 (2014) PAGES 6604–6618In Fig. 4G, in the foxi1 panel, the images in Fig. 4G, i and l, corresponding to “smad1 MO” and “smad5 MO + samd1/9 mRNA” samples, respectively, were inadvertently reused during figure preparation. This error has now been corrected using images pertaining to each treatment and sample. This correction does not affect the results or conclusions of the work.jbc;295/52/18650/F4F1F4Figure 4G.




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Healthcare comes to standstill in east Aleppo as last hospitals are destroyed




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A musical about malignancy




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Lack of evidence for interventions offered in UK fertility centres




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Doctor alleged to have performed “designer vagina” surgery won’t be prosecuted




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Overdiagnosis of thyroid cancer




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Preserving fertility in girls and young women with cancer




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Seven days in medicine: 23-29 November 2016




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Generics have a chequered recent history




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Low molecular weight heparin does not prevent VTE after knee arthroscopy, studies show




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Constitutional symptoms in a young person




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Anti-bullying programme is launched by orthopaedic trainees




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Government recognises contribution of EU workers to the NHS, says health minister




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Royal College of Surgeons launches postgraduate surgical certificate