1

Deconvoluting MLL1-dependent pathways in hematopoiesis and leukemogenesis




1

Abstracts from the 2nd International Norges Teknisk-Naturvitenskapelige Universitet (NTNU) Symposium: Day 1—Immunotherapy and Hematology




1

50, 100 & 150 Years Ago

Innovation and discovery as chronicled in Scientific American




1

Philip W. Anderson (1923–2020)




1

Coronavirus in context: Scite.ai tracks positive and negative citations for COVID-19 literature




1

Effect of non-pharmaceutical interventions to contain COVID-19 in China




1

COVID-19 mental-health responses neglect social realities




1

Daily briefing: More than 1 billion people face unbearable temperatures within 50 years




1

Let COVID-19 expand awareness of disability tech




1

Determination of RNA structural diversity and its role in HIV-1 RNA splicing




1

HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α




1

The β-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasis




1

The nuclear oncoprotein Fra-1: a transcription factor knocking on therapeutic applications’ door




1

Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer




1

CDK11 is required for transcription of replication-dependent histone genes




1

Real-time observation of CRISPR spacer acquisition by Cas1–Cas2 integrase




1

COVID-19 assistance needs to target energy insecurity




1

Ronald S. Duman, PhD (1954–2020)




1

Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction




1

Thank you to all 2019 Mucosal Immunology Reviewers




1

Seasonal and pandemic influenza: 100 years of progress, still much to learn




1

The functions of IL-23 and IL-2 on driving autoimmune effector T-helper 17 cells into the memory pool in dry eye disease




1

Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals




1

100 years of influenza research seen through the lens of Covid-19




1

The new scope of virus taxonomy: partitioning the virosphere into 15 hierarchical ranks




1

Exogenous hormone use, reproductive factors and risk of intrahepatic cholangiocarcinoma among women: results from cohort studies in the Liver Cancer Pooling Project and the UK Biobank




1

Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




1

Potential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors




1

The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer




1

Androgen receptor phosphorylation at serine 81 and serine 213 in castrate-resistant prostate cancer




1

Clinical utility of the exosome based ExoDx Prostate(<i>IntelliScore</i>) EPI test in men presenting for initial Biopsy with a PSA 2–10 ng/mL




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COVID-19 outcomes in patients with hematologic disease




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COVID-19, HCT and wine




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The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors




1

LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression




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MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer

Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers.




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




1

Dermatophagoides pteronyssinus peptidase 1 (DERP1)

In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma.




1

c-jun N-terminal kinase (JNK); MAP kinase 1 (MAPK1; ERK-2); MAPK3 (ERK-1)

In vitro and rodent studies suggest ophiopogonin D could help prevent doxorubicin-induced cardiotoxicity.




1

Sortilin 1 (SORT1)

Mouse studies suggest inhibiting SORT1 in macrophages and T cells could help treat atherosclerosis.




1

Topoisomerase II binding protein 1 (TOPBP1)

Mouse and cell culture studies suggest inhibiting TOPBP1 could help treat cancer.




1

Epidermal growth factor receptor 1 (EGFR1; ErbB1; HER1); HER2 (EGFR2; ErbB2; neu); HER3 (EGFR3; ErbB3); VEGF

Tumor cell and mouse studies suggest tetravalent antibodies that target four different antigens could help treat cancers resistant to HER-targeted therapies.




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LIS1 cracks open dynein




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Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity




1

FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome




1

Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice




1

Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40




1

UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53




1

Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation




1

Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities