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Watch the Hacienda live stream as the ultimate house party returns

Hacienda Classical will perform at the second stay-at-home rave from the legendary club and United We Stream



  • Music & Nightlife

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Radford family transform garden into kids play park in just 48 hours

Britain's biggest family, who live in Morecambe, revealed how they did it in their latest Youtube video




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More than 200 homes and businesses hit by power cut in Wythenshawe

Electricity North West said the power might not be restored until 6pm tonight



  • Greater Manchester News

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Make way for the milkman as lockdown brings these old school businesses back

'That old fashioned, community spirit seems to be back'




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Man arrested on suspicion of murder after woman's body found in house

Police have arrested a 40-year-old man who remains in custody for questioning



  • Greater Manchester News

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LIVE updates as Grant Shapps holds UK daily coronavirus press conference

The Transport Secretary will lead Saturday's briefing




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Using digital twins to design more sustainable cities

Over the past several years, a collaboration at HLRS has been developing a digital twin of Herrenberg, a small city just outside of Stuttgart, Germany. The Herrenberg study has already provided valuable information for city planners and government officials in the state of Baden-Württemberg, and paves the way for improving the model to include additional kinds of data.




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Editorial: US healthcare must take a more proactive approach to prepare for future disasters

The COVID-19 pandemic has revealed major deficiencies and inequities in the US healthcare system, shining a spotlight on improvements that must be made to steel the country for future disasters, argues Maia.




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Olanzapine may help control nausea, vomiting in patients with advanced cancer

Olanzapine, a generic drug used to treat nervous, emotional and mental conditions, also may help patients with advanced cancer successfully manage nausea and vomiting unrelated to chemotherapy. These are the findings of a study published Thursday, May 7, 2020 in JAMA Oncology.




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Treatment for opioid use disorder is rare in hospitals, study finds

Despite a national opioid-related overdose epidemic that continues to claim tens of thousands of lives annually, a new nationwide study shows that a scant proportion of hospitalized patients with opioid use disorder receive proven life-saving medications both during and after they're discharged.




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New invisibility concept and miniaturization of photonic circuits using ultrafast laser

Thanks to its unique three-dimensional manufacturing capacity, ultrafast laser writing is a prime candidate to meet the growing demand for the miniaturization of photonic circuitry, e.g., for scaling up optical quantum computers capacity. Towards this goal, scientists from Canada discovered a phenomenon related to the material electronic resonance that allows a much greater miniaturization of the laser written devices. Surprisingly, the new phenomenon allows other intriguing applications such as a new concept of invisibility.




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How herpes simplex virus can evade the immune response to infect the brain

A research team has discovered a molecular mechanism that helps Herpes simplex virus (HSV1) evade the innate immune system and infect the brain causing a rare disease with high mortality. The study from Aarhus University, University of Oxford, and University of Gothenburg, led by first author Chiranjeevi Bodda in Søren Paludan's lab, will be published May 8 in the Journal of Experimental Medicine (JEM).




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Pangolins may possess evolutionary advantage against coronavirus

Pangolins lack two genes that function to sound the alarm when a virus enters the body, triggering an immune response in most other mammals. The findings from the Medical University of Vienna, Austria, are significant because, while the exotic animals can be carriers of coronavirus, they appear able to tolerate it through some other unknown mechanism. Understanding how pangolins are able to survive coronavirus may point to possible treatment options for humans.




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IST Austria scientists demonstrate quantum radar prototype

Physicists at the Institute of Science and Technology Austria (IST Austria) have invented a new radar prototype that utilizes quantum entanglement as a method of object detection. This successful integration of quantum mechanics into our everyday devices could significantly impact the biomedical and security industries. The research is published in the journal Science Advances.




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Prehistoric sea creatures evolved pebble-shaped teeth to crush shellfish

Ichthyosaurs were marine reptiles during the time of the dinosaurs, and scientists don't know much about their ancestry. But by CT-scanning the fossil of one of the first ichthyosaurs, scientists discovered pebble-shaped teeth hidden in its short snout. These strange teeth, probably used for crushing the shells of snails and clam-like bivalves, help illuminate the ways that early ichthyosaurs filled different roles in Triassic marine ecosystems.




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Gene therapy in mice builds muscle, reduces fat

Researchers at Washington University School of Medicine in St. Louis found that gene therapy in mice helped build strength and significant muscle mass quickly, while reducing the severity of osteoarthritis. The gene therapy also prevented obesity, even when the mice were fed a high-fat diet.




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KIST-CUK research team develops vaccine platform applicable to various viruses

MERS, which struck South Korea in a 2015 outbreak, was caused by a coronavirus--the same family of viruses that is responsible for COVID-19. Recently, a Korean research team announced that it had developed a new vaccine platform using RNA-based adjuvants for the MERS coronavirus. The research team successfully conducted an experiment on nonhuman primates. It is expected that the new vaccine platform will soon be applicable to the development of a COVID-19 vaccine, an urgent global health priority.




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NTU Singapore scientists develop sustainable way to extract chitin from prawn shells

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a green way to create chitin, by using two forms of food waste - prawn shells and discarded fruit - and fermenting them.




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USF researchers find human-driven pollution alters the environment even underground

The Monte Conca cave system in Sicily is showing signs of being altered by pollution from above.




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Plasma medicine research highlights antibacterial effects and potential uses

As interest in the application of plasma medicine -- the use of low-temperature plasma (LTP) created by an electrical discharge to address medical problems -- continues to grow, so does the need for research advancements proving its capabilities and potential impacts on the health care industry. Across the world, many research groups are investigating plasma medicine for applications including cancer treatment and the accelerated healing of chronic wounds, among others.




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New study shines light on mysterious giant viruses

In recent years, giant viruses have been unearthed in several of the world's most mysterious locations, from the thawing permafrost of Siberia to locations unknown beneath the Antarctic ice. But don't worry, 'The Thing' is still a work of science fiction. For now.




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Pediatric coronavirus disease (COVID-19) x-ray, CT in review of new lung disorders

Although the clinical symptoms of SARS, H1N1, MERS, EVALI, and COVID-19 may be nonspecific, some characteristic imaging findings are emerging, says the American Journal of Roentgenology (AJR). Careful evaluation of the distribution, lung zone preference, and symmetry of the abnormalities with an eye for a few unique differentiating imaging features can allow radiologists to offer a narrower differential diagnosis in pediatric patients, leading to optimal patient care.




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Debenhams accused of 'stealing' as retailer demands 90% discount on clothes from suppliers already at UK ports

ITV News has seen correspondence from Debenhams’ administrator to Bangladeshi suppliers demanding a 90% discount on garments orders.




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Care company launch own We Care badge to support workers during coronavirus pandemic

A North East based care provider, Wellburn Care Homes, has launched their own We Care badge aiming to show support for care workers.




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'Almost criminal' coronavirus testing isn't available for everyone, former Prime Minister Gordon Brown says

Former Prime Minister Gordon Brown has called for "more than 200,000" coronavirus tests to be carried out.




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Coronavirus: 'Delays in action on care home crisis cost thousands of lives', documents reveal

Data which identified a massive in Covid-19 was sent to ministers a month before the government's Care Home Action Plan was published.




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Man arrested on suspicion of attempting to murder police officer

The officer’s injuries are not thought to be life-threatening.




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Medieval arrows caused similar injuries to gunshots, say archaeologists

Arrows fired from longbows could penetrate right through the human skull creating small entry and large exit wounds.




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First patients given plasma in coronavirus treatment trial

Hospitals in London and Birmingham have been supplied with fourteen units of convalescent plasma to see if it helps people who are battling




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Special front cover of The Big Issue created by Gruffalo illustrator

Characters created by Axel Scheffler from his popular books with Julia Donaldson are on the cover.




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Duchess of Cambridge calls on budding photographers to capture life under coronavirus lockdown

The Duchess of Cambridge has teamed up with the National Portrait Gallery to launch the Hold Still project.




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Warning over ‘perilous future’ for London Zoo in face of lockdown

Zoological Society of London warns it is facing a very challenging situation as its core income from London and Whipsnade zoos has dried up.




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BAME groups ‘two to three times more likely to die from coronavirus’

The likelihood of death from Covid-19 is significantly higher among England’s BAME communities than the general population, researchers say.




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Only half of businesses prepared to return to pre-crisis levels after lockdown lifts

One in twenty businesses said they would be unable to viably operate as long as social distances measures are still enforced.




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Tesla chief Elon Musk set for £600m payday after targets reached

He will receive nearly 1.69 million stock options priced at 350.02 dollars (£285).




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China declares whole country ‘at low risk’ after coronavirus pandemic

There have been no deaths reported from the virus in China for more than three weeks.




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'He spat at me and said have some of my corona': Policing Britain during the coronavirus lockdown

ITV Tonight is out with Merseyside Police to investigate the extraordinary impact the pandemic is having on their ability to combat crime.




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Bank of England warns coronavirus could cause biggest economic slump in 300 years

The Bank of England said the economy could contract by as much as 3% in the first quarter.




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Shipment of 400,000 delayed protective gowns from Turkey deemed unusable

A shipment of 400,000 gowns from Turkey which was part of a delayed consignment of PPE has been impounded after falling short of standards.




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At least eight dead and thousands taken to hospital after chemical leak in India

The incident led to panic among locals within a three-kilometre radius.




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People from black backgrounds four times more likely to die from virus than people from white backgrounds, ONS finds

People from black backgrounds are four times more likely to die from coronavirus than people from white backgrounds, new statistics suggest.




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Why no one really knows the economic outcome of the coronavirus crisis

From a rapid recovery to prolonged depression and everything in between, the range of possible outcomes from the coronavirus crisis is vast.




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Who has a torch in the coronavirus darkness?

The big question is whether you want to focus on the 2020 bit of the Bank of England's illustrative scenario, which shows a 14% fall in GDP.




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Nicola Sturgeon says lockdown must continue in Scotland but people may be allowed out more than once per day to exercise

Scotland's First Minister Nicola Sturgeon says the lockdown period in the country should be extended.




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Passengers told to wear face coverings and gloves at some of UK's busiest airports

Limited temperature screening will also be trialled at the airports in coming weeks.




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Lockdown: Any easing of coronavirus restrictions in England will be 'very limited', No 10 says

The government will move with "maximum caution" when lifting coronavirus lockdown restrictions in England, Number 10 has said.




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UK coronavirus death toll increases to 30,615 as further 539 deaths confirmed

Dominic Raab announced the latest figures during the daily briefing.




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Senior Government Advisor says coronavirus is 'discriminatory'

Newly released figures show that certain ethnicities were at greater risk of Covid-19 related deaths.




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UK gives mass round of applause thanking key coronavirus workers in nationwide Clap For Our Carers

For a seventh week in a row, millions of people across the United Kingdom have shown their appreciation for NHS and key workers.




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Spread of coronavirus in hospitals and care homes is the big problem, writes Robert Peston

In the community, the rate of transmission is probably as low as 0.5/0.6, which means its progress through the population has been arrested.