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Telomere-based risk models for the early diagnosis of clinically significant prostate cancer




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Clinical utility of the exosome based ExoDx Prostate(<i>IntelliScore</i>) EPI test in men presenting for initial Biopsy with a PSA 2–10 ng/mL




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Growth of microorganisms in an interfacially driven space bioreactor analog

npj Microgravity, Published online: 08 April 2020; doi:10.1038/s41526-020-0101-4

Growth of microorganisms in an interfacially driven space bioreactor analog




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Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity




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Simultaneous noninvasive recording of electrocardiogram and skin sympathetic nerve activity (neuECG)




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npj Aging and Mechanisms of Disease




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WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




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Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs

miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors.




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Influenza A virus hemagglutinin

Cell and mouse studies have identified pentacyclic triterpenoid analogs that could help treat influenza infections and have lower risk for resistance than amantadine.




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Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4

Mouse studies suggest chemically modified carbohydrate conjugates could be useful as antigens for the development of cancer vaccines.




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Tripartite motif containing 37 (TRIM37)

In vitro and mouse studies suggest inhibiting TRIM37 could help treat breast cancer.




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Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity




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Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity




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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states




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Reviewer Recognition




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The rise of integrated quantum photonics




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Nature Photonics




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Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy




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Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism




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Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Nanomedicines based on nanoscale metal-organic frameworks for cancer immunotherapy




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Acta Pharmacologica Sinica




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Ironing out mucosal healing




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Universal screening for hepatitis C virus infection should be linked to universal treatment access




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Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities




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Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys




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Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression




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Nuclear receptor crosstalk — defining the mechanisms for therapeutic innovation




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Combining radiolabelled therapies for neuroendocrine neoplasms




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Nanoscale nights of COVID-19




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Probing nanoscale fluctuation of ferromagnetic meta-atoms with a stochastic photonic spin Hall effect




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Listening to the sound of a bacterium




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Publisher Correction: Optomechanical detection of vibration modes of a single bacterium




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Nonoperative treatment of traumatic spinal injuries in Tanzania: who is not undergoing surgery and why?




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Expert opinion—management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors




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Peter Ward: 'Membership organisations can thrive and prosper'




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Special products for specialist cleaning




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Mechanistic insight into the spread of tau pathology




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Parkinson disease and the immune system — associations, mechanisms and therapeutics




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Monogenic small vessel diseases — rare but still important




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Treatment and management of cognitive dysfunction in patients with multiple sclerosis




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Noncanonical amino acids on display




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Mining bacteria for biosensors




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History Against Sectarianism, The Telegraph

In December 1947, the annual Indian History Congress was held in Bombay. The President-elect that year was Professor Mohammad Habib of the Aligarh Muslim University, a historian of early medieval India, known especially for his studies of the Delhi Sultanate. From the late 1930s, many students and faculty at AMU had been active supporters of [...]




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Why Authoritarianism is Bad for Science, But Bigotry is Even Worse

There have been many protests against the Citizenship Amendment Bill (now Act), and there will be many more. This piece of legislation strikes at the heart of the Constitution, seeking to make India another country altogether. It is thus that so many people from so many different walks of life have raised their voices against [...]




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The Folly and Vanity of The Project to Redesign New Delhi, The Wire

Six years ago, the then editor of the Hindustan Times invited me to write a fortnightly column. I agreed, on condition that there would be no censorship. While occasionally some changes to my text were made without my consent, there was no attempt to get me to rewrite my column or change its arguments. Until [...]




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Modeling shield immunity to reduce COVID-19 epidemic spread




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Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.