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BJP accuses Congress of releasing election manifesto during “silence” period in Jharkhand

Mr. Patra claimed that the Congress wanted to give 4% reservation to the Muslim organisations and contractors in public tenders




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Govt. charges BRS with hatching conspiracies to stall development projects for political gains

Dy CM says involvement of BRS leader in Lagacharla incident exposes the party’s intentions




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Google.org awards USD 1 mn grant to Karya to boost ai-based economic opportunities for low-income communities




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India will continue to be vocal about climate finances at COP29




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TcESTIME: predicting high-temperature hydrogen-based superconductors

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC04465G, Edge Article
Open Access
Trinidad Novoa, Matías E. di Mauro, Diego Inostroza, Kaoutar El Haloui, Nicolas Sisourat, Yvon Maday, Julia Contreras-García
Superconductivity can be considered among the most exciting discoveries in material science of the XXth century. However, the hard conditions for the synthesis and the difficult characterization, make the statement...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis of highly condensed phospholes by Lewis acid-assisted dehydrogenative Mallory reaction under visible light irradiation

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05657D, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ikki Kamiyoshi, Yuki Kojima, Shibo Xu, Kosuke Yasui, Yuji Nishii, Koji Hirano
A photo-promoted oxidative cyclization, that is, Mallory reaction of 2,3-diarylbenzophopholes has been developed. With an assistance of Bi(OTf)3 Lewis acid, the reaction proceeds smoothly under visible light irradiation even without...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chandigarh's air quality continues to be worse than Punjab, Haryana




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DRDO conducts maiden flight test of Long-Range Land Attack Cruise Missile (LRLACM)




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HC modifies the status quo order on maintaining constructions for Tent City in two islands of Lakshadweep




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Iran executes in public a serial rapist convicted in dozens of cases

Iran’s state media say authorities have executed in public a man convicted of raping dozens of women over two decades




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Preventing SARS-CoV-2 infection using Fv-antibodies targeting the proprotein convertase (PPC) cleavage site

RSC Med. Chem., 2024, 15,3704-3710
DOI: 10.1039/D4MD00552J, Research Article
Jaeyong Jung, Jeong Soo Sung, Soonil Kwon, Hyung Eun Bae, Min-Jung Kang, Joachim Jose, Misu Lee, Jae-Chul Pyun
Fv-antibodies targeting the PPC region of SARS-CoV-2 to prevent infection, screened from an Fv-antibody library (displayed on outer membrane of E. coli cell).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity

RSC Med. Chem., 2024, 15,3711-3727
DOI: 10.1039/D4MD00584H, Research Article
Sara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-Dias
A series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A photoswitchable CENP-E inhibitor with single blue-green light to control chromosome positioning in mitotic cells

RSC Med. Chem., 2024, 15,3795-3799
DOI: 10.1039/D4MD00458B, Research Article
Kazuya Matsuo, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki
A photoswitchable centromere-associated protein E (CENP-E) inhibitor based on the 4-methylaminoazobenzene photoswitch is reported, which is characterized with cistrans photoisomerization with blue-green light and fast thermal relaxation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery

RSC Med. Chem., 2024, 15,3695-3703
DOI: 10.1039/D4MD00546E, Research Article
Miyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke Demizu
A novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.
The content of this RSS Feed (c) The Royal Society of Chemistry




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IIT Madras to conduct two-day summit on extended reality

The aim is to develop academic partnership programmes to boost research in XR or extended reality




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IIT-M students develop robot for O.P. Jindal university’s Constitution Museum

It is trained to respond to questions from visitors in Hindi and English, IIT-M professor says




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Leaders of various parties condemn attack on govt. doctor




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Rival Zomato's CEO congratulates Swiggy on stock market listing

Swiggy got listed at ₹420, a jump of nearly 8% from the issue price on the NSE




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Wall Street makes wagers on the likely winners and losers in a second Trump term

Wall Street is already making big bets on what take two for a White House led by Donald Trump will mean for the economy and markets




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Developed nations need to triple their contribution to make climate finance credible: Avinash Persaud

Currently, developed nations are expected to pay $100 billion a year but they haven’t stuck to agreed targets, and this system ends next year.




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Jagan dares govt. to arrest him, says will continue to ‘expose failures’




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Police book Sri Reddy for posting ‘defamatory content’ against Chandrababu Naidu, Pawan Kalyan




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Andhra Pradesh High Court strikes down PIL seeking to restrain police from taking action on ‘abusive content on social media’




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Supreme Court sets pan-India guidelines against ‘bulldozer justice,’ calls demolitions without due process unconstitutional

The Apex court maintains that these guidelines do not apply in cases of unauthorized public land construction or where demolition is mandated by a court ruling




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29th Climate Conference (COP) tracker | Day 2 LIVE: Key speeches, UK NDC, and India’s reaction at 5 p.m. on November 13

Vibhuti Garg, an Associate and Senior Energy Specialist with over 13 years of experience in the energy sector, will guide us through the implications of these financial negotiations and the potential impacts on global energy transitions and climate commitments at 5 p.m. on November 13




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Uncontrolled diabetes increases risk of hearing loss; doctors call for more awareness, screening

Hearing loss occurs twice as frequently in patients with uncontrolled diabetes as compared to the non-diabetic population, doctors say, calling for screening to be included in routine diabetes care




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Doctors believe continual upskilling is crucial for diabetes management: survey

The survey also found that doctors were interested in using AI tools for early detection and personalised treatment plans to manage diabetes




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Karnataka bypolls: Channapatna, Shiggaon and Sandur constituencies witness overall turnout of 76.9% till 5 p.m.

A total of 45 candidates are in the fray in these byelections




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Karnataka bypolls: A few residents of Savanur boycott polling in Shiggaon Assembly constituency

Some families at Dandinpet in Savanur boycotted the bypolls over not being given record of occupancy rights to them.




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PUCL condemns opposition to Dalits’ entry into temple in Mandya village




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Illegal export of iron ore from Belekeri port: Karnataka High Court suspends sentence and grants bail to MLA Satish Sail and five other convicts




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Mysuru to host conference on AI and Deeptech




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Why US chess champ Levon Aronian is connecting with the Armenian community in Chennai

Chess champion Levon Aronian, who competed in Chennai Grand Masters recently, on future Indian chess superstars




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Vikarabad violence: KTR condemns former BRS MLA’s arrest, says farmers detained were ill-treated by police




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Residents raise concerns over water quality and odour from Vellalore dump yard




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The globally-acclaimed Candlelight Concert is now in Chennai. Listen to classical and contemporary music at Museum Theatre, amidst thousands of candles

The first concert on November 15 will feature tunes from Tamil and Hindi films, followed by tributes to Coldplay, Mozart, Queen, and Abba in the upcoming months



  • Life & Style

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Mumps outbreak in Thrikkakara under control, says Health dept.




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Watch: Can Trump’s win make it worse for Indian economy? | Business Matters

Private investment hasn’t really taken off as expected and industry watchers ascribed that to lack of adequate demand. With Trump slated to be next in the White House, how dark do things really look for India?




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​Surprise spike: On the Consumer Price Index

October’s inflation pace surpasses expectations and dashes rate cut hopes for now




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Thiruvalluvar University in Vellore seeks contributions from public for its Academic Development Fund




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Don’t follow self-healing methods to control diabetes, says diabetologists




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Wet spell to continue over Tamil Nadu interspersed with intense rainfall over various districts till the weekend

With the weather system weakening, IMD has withdrawn heavy rainfall alert for Chennai




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UPPSC aspirants protest continues for third day over exam format 

The job aspirants protest multiple shifts and score normalisation in exams, demanding a fair and unified testing process




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Congress demands white paper on government recruitments in Goa since 2019

The Congress attack came a day after a woman member of BJP’s mahila morcha was arrested in connection with the jobs scam




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Youth ‘hooked to radical content online’ detained in J&K’s Kulgam

The youth was “misusing social media for radical propaganda aimed at to instigate common people against the Government of India and also glamourising terrorism in J&K”




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Congress has led Karnataka to bankruptcy, alleges Tejasvi Surya in Mumbai

Under the Congress regime, Karnataka is facing extreme financial crisis; the government has been struggling to manage the State’s economy due to its mismanagement of funds, says the BJP MP




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Vikarabad case: Former BRS MLA names KTR in confession




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Constable killed in accident




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Telangana’s Congress government is busy implementing programmes without thought

There is a wide gap between planning and implementation.




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India’s tea, sugar exports raise sustainability concerns at home | Explained

Exports help strengthen India’s economy by increasing revenue but the rapid surge in exports poses multiple challenges to the sustainability of production, processing, and distribution systems