(United States Fourth Circuit) - On petition for a redetermination of federal income tax deficiencies brought by a 501(c)(4) nonprofit homeowners association, the Tax Court's ruling against the association is affirmed, where the net income derived by the association from its parking lots and beach club benefitted the private interests of the association members rather than the general public, and therefore was not "substantially related" to the association's purpose of promoting social welfare, but rather was taxable as "unrelated business taxable income" under IRC sections 511-513.

(United States Fifth Circuit) - Affirmed. The district court's grant of a defense motion for summary judgment in an Age Discrimination Employment Act claim was proper because the plaintiff failed to raise a genuine question of material fact about the company's reasons for firing him during a period in which the company halved its workforce and fired thousands of workers.

(United States Third Circuit) - Affirming the dismissal of an in rem suit filed against a ship for cargo damage sustained in transit because liability for the damage was covered by the carrier's bill of lading, which included a forum selection clause requiring suit be brought in South Korea because although South Korean courts would not allow an in rem suit, the plaintiff could have brought an in personam suit and chose not to do so for strategic reasons and the foreign forum selection clause did not violate the Carriage of Goods by Sea Act.

(United States Fifth Circuit) - In a contractual dispute between two companies in the oil-drilling business, vacated a bench trial judgment, in part. The contract related to exploratory drilling for offshore oil.

(United States Fifth Circuit) - In a contractual dispute between two companies in the oil-drilling business, vacated a bench trial judgment, in part. The contract related to exploratory drilling for offshore oil.

(United States First Circuit) - Affirmed two men's convictions of a conspiracy to distribute cocaine base. The defendants raised a variety of constitutional and evidentiary arguments against their convictions. However, the First Circuit found no error in any of their claims of error.

Since the outbreak of COVID-19, face masks have been in high demand. One company decided to take an eco-friendly approach to manufacturing and supplying the public with protective masks. The Professional Association of Diving Instructors (PADI) partnered with the sustainable sportswear company Rash’r to turn plastic pollution found in the ocean into face masks.

All proceeds from the masks go directly back into the manufacturing of more masks to help recycle plastics from the ocean. The masks feature a number of ocean-themed designs and include special sizes for kids. The company has received more than 15,000 mask pre-orders in just a few weeks—which has helped recycle more than 1,300 pounds (590 kg) of ocean pollution. The U.S. Centers for Disease Control and Prevention (CDC) now recommends that people wear cloth face masks to prevent the spread of COVID-19 in public places. The masks made by PADI offer a sustainable alternative to the N95 respirator masks being reserved for health care workers.

The post Team Spotlight: Getting to Know Ocean Blue’s James Stamatis appeared first on Ocean Blue Fishing Adventures.

Although CEACAM1 (CC1) glycoprotein resides at the interface of immune liver injury and metabolic homeostasis, its role in orthotopic liver transplantation (OLT) remains elusive. We aimed to determine whether/how CEACAM1 signaling may affect hepatic ischemia-reperfusion injury (IRI) and OLT outcomes. In the mouse, donor liver CC1 null mutation augmented IRI-OLT (CC1-KO→WT) by enhancing ROS expression and HMGB1 translocation during cold storage, data supported by in vitro studies where hepatic flush from CC1-deficient livers enhanced macrophage activation in bone marrow–derived macrophage cultures. Although hepatic CC1 deficiency augmented cold stress–triggered ASK1/p-p38 upregulation, adjunctive ASK1 inhibition alleviated IRI and improved OLT survival by suppressing p-p38 upregulation, ROS induction, and HMGB1 translocation (CC1-KO→WT), whereas ASK1 silencing (siRNA) promoted cytoprotection in cold-stressed and damage-prone CC1-deficient hepatocyte cultures. Consistent with mouse data, CEACAM1 expression in 60 human donor liver biopsies correlated negatively with activation of the ASK1/p-p38 axis, whereas low CC1 levels associated with increased ROS and HMGB1 translocation, enhanced innate and adaptive immune responses, and inferior early OLT function. Notably, reduced donor liver CEACAM1 expression was identified as one of the independent predictors for early allograft dysfunction (EAD) in human OLT patients. Thus, as a checkpoint regulator of IR stress and sterile inflammation, CEACAM1 may be considered as a denominator of donor hepatic tissue quality, and a target for therapeutic modulation in OLT recipients.

Organ shortage continues to limit the lives of patients who require liver transplantation. While extending criteria for liver organs provides a needed resource, tissue damage from prolonged ischemic injury can result in early allograft dysfunction and consequent rejection. In this issue of the JCI, Nakamura et al. used a mouse transplantation model with prolonged ex vivo cold storage to explore liver graft protection. The authors found that liver grafts with absent carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) exhibited increased ischemia-reperfusion injury inflammation and decreased function in wild-type recipients. The authors went on to correlate CEACAM1 levels with postreperfusion damage in human liver transplant recipients. Notably, this study identified a potential biomarker for liver transplant donor graft quality.

Josh Kelly suffered from epilepsy, a brain disorder that forced him to drop out of high school nine days before graduation. For nearly a decade, Kelly attended Idaho State University working toward a degree in geology, with his service dog, a black pit bull named Cletus, by his side. The pair would dutifully walk two miles both ways to catch the bus to campus.

Unfortunately, Kelly passed away in February just two classes shy of his degree. Nonetheless, ISU granted him a posthumous degree on May 10. In the young man's place, Kelly's tearful father, Terrell, walked across the stage with Cletus by his side and accepted the diploma.

Earlier this year I warned that The Ocean Cleanup would catch and kill floating marine life. This week they announced they’re collecting plastic, and their picture…

Donald Trump issued an executive order late Thursday that environmentalists warned will accelerate the corporate exploitation of oceans by relaxing regulations on and streamlining the construction of industrial offshore aquaculture facilities, which critics deride as "floating factory farms" that pump pollution and diseases into public waters.

The Don't Cage Our Ocean Coalition, which was formed to oppose ocean industrial fish farming, said in a statement that Trump's Executive Order on Promoting American Seafood Competitiveness and Economic Growth "mandates federal agencies to craft a program for rapid authorization of industrial offshore aquaculture facilities, which use giant floating cages to cultivate finfish, allowing toxic pollution to flow into open waters."

"The federal government should strengthen local food security during this health crisis by supporting sustainable seafood, rather than allowing corporations to pollute the ecosystems we depend on."
—Marianne Cufone, environmental attorney

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In an effort to find a balance between protecting the significant investment in our cellular devices and protecting the planet, LifeProof has developed a phone case that sources materials diverted from the ocean and simultaneously supports organizations directly involved in providing safe water, protecting ocean life and maintaining river habitat. [...]

DigitalOcean, one of the biggest modern web hosting platforms, recently hit with a concerning data leak incident that exposed some of its customers' data to unknown and unauthorized third parties. Though the hosting company has not yet publicly released a statement, it did has started warning affected customers of the scope of the breach via an email. According to the breach notification

Frank Ocean Blonde and Endless New Orleans-born and L.A.-raised Frank Ocean has been one of the most consistently interesting and mysterious pop stars of the 2010’s. After helping shape the sound of boundary-pushing and controversial L.A. rap collective Odd Future, Ocean released his first mixtape, Nostalgia Ultra in 2011. Frank Ocean was then highly featured … Continue reading "Frank Ocean’s Two Album Splash: Endless and Blonde"

Multiple Grade One-winning chaser Un De Sceaux left the yard of Willie Mullins for the final time on Monday.

Tá cead tugtha ag an Vatacáin d'ord Siúracha Cráifeacha na Carthannachta Ospidéal agus tailte Naomh Uinseann i mBaile Átha Cliath a bhronnadh ar an Stát trí chomhlacht dar teideal Grúpa Sealbhaíochta Cúram Sláinte Naomh Uinseann.

Tá sé deimhnithe ag an Aire Oideachais agus Eolaíochta, Joe McHugh go bhfuil scrúduithe na hArdteistiméireachta don bhliain seo curtha ar ceal agus go bhfuil Plean "C", mar a bhfaighfidh daltaí grádanna tuartha óna meánscoil féin, le teacht ina n-áit.

When talking about the impacts of climate change, we mostly hear about changes to land and the planet’s surface or atmosphere. However, most of the warming is going into the oceans where a lot of ecosystem changes are also occurring.

This update includes a couple of info graphics and charts as well as a video from an ocean and climate scientist that explains this further.

Read full article: Climate Change Affects Biodiversity

After ending print publication in 2019 and moving to online nonprofit model, Nuvo will cease operations.

The Conrad Indianapolis temporarily suspended operations as occupancy rates for Downtown hotels nosedive because of the coronavirus outbreak.

After ending print publication in 2019 and moving to online nonprofit model, Nuvo will cease operations.

She is the youngest woman to row solo across the Indian Ocean. Find out more in this week's Media English.

Indianapolis Prize finalist Sylvia Earle was the first woman to act as an Explorer in Residence for the National Geographic Society.

Mediterranean sediments are shown to have up to 1.9 million tiny plastic pieces per square metre.

Princess Cruises were the first cruise line to introduce the Ocean Medallion smart wearable device that is supposed to change the way you cruise. It helps you board the ship faster, find your way around the ship, order food and drink to wherever you are on the ship, gamble and play games , locate your friends and more. But how does it really work? What are the pros and cons? Find out my thoughts, take and review of the Princess Cruises Ocean Medallion.

Hear about a Baltic Cruise on Viking Ocean as the Amateur Traveler talks to Mary Jo Manzanares from travelingwithmj.com about their recent Viking Homelands cruise on the Viking Sea.

Part of the Antarctic diary promo for the BBC UK Homepage

The 2019 Chatham House Prize is awarded to Sir David Attenborough and Julian Hector, head of BBC Studios Natural History Unit, for the galvanizing impact of the Blue Planet II series on tackling ocean plastic pollution.

The respiratory epithelium comprises polarized cells at the interface between the environment and airway tissues. Polarized apical and basolateral protein secretions are a feature of airway epithelium homeostasis. Human respiratory syncytial virus (hRSV) is a major human pathogen that primarily targets the respiratory epithelium. However, the consequences of hRSV infection on epithelium secretome polarity and content remain poorly understood. To investigate the hRSV-associated apical and basolateral secretomes, a proteomics approach was combined with an ex vivo pediatric human airway epithelial (HAE) model of hRSV infection (data are available via ProteomeXchange and can be accessed at https://www.ebi.ac.uk/pride/ with identifier PXD013661). Following infection, a skewing of apical/basolateral abundance ratios was identified for several individual proteins. Novel modulators of neutrophil and lymphocyte activation (CXCL6, CSF3, SECTM1 or CXCL16), and antiviral proteins (BST2 or CEACAM1) were detected in infected, but not in uninfected cultures. Importantly, CXCL6, CXCL16, CSF3 were also detected in nasopharyngeal aspirates (NPA) from hRSV-infected infants but not healthy controls. Furthermore, the antiviral activity of CEACAM1 against RSV was confirmed in vitro using BEAS-2B cells. hRSV infection disrupted the polarity of the pediatric respiratory epithelial secretome and was associated with immune modulating proteins (CXCL6, CXCL16, CSF3) never linked with this virus before. In addition, the antiviral activity of CEACAM1 against hRSV had also never been previously characterized. This study, therefore, provides novel insights into RSV pathogenesis and endogenous antiviral responses in pediatric airway epithelium.

Expert

Imagine trying to describe the circulation and temperatures across the vast expanse of our oceans. Good models of our oceans not only benefit fishermen on our coasts but farmers inland as well. Until recently, there were neither adequate tools nor enough data to construct models. Now with new data and new mathematics, short-range climate forecasting for example, of an upcoming El Nino is possible.There is still much work to be done in long-term climate forecasting, however, and we only barely understand the oceans. Existing equations describe ocean dynamics, but solutions to the equations are currently out of reach. No computer can accommodate the data required to approximate a good solution to these equations. Researchers therefore make simplifying assumptions in order to solve the equations. New data are used to test the accuracy of models derived from these assumptions. This research is essential because we cannot understand our climate until we understand the oceans. For More Information: What.s Happening in the Mathematical Sciences, Vol 1, Barry Cipra.