ay

'Nimmi was always ahead of her time'

'She was gutsy and rebellious enough to take on roles other more conventional actresses wouldn't dare and she excelled in them.'




ay

Akshay in Singham 3

Salman may direct Tiger 3... Katrina drops Vikas Bahl film...





ay

'It feels like a close family member has passed away'

'Ever since I heard about his death this morning, I have not been able to control my tears,' says Patcy N who interviewed the actor often




ay

Untargeted metabolomics revealed therapeutic mechanisms of icariin on low bone mineral density in older caged laying hens

Food Funct., 2020, 11,3201-3212
DOI: 10.1039/C9FO02882J, Paper
Jie Huang, Yanping Hu, Xiaofeng Tong, Lei Zhang, Zhengwang Yu, Zhongxin Zhou
Untargeted metabolomics revealed the therapeutic effects and mechanisms of icariin on low bone mineral density in older caged laying hens.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Inducing secondary structural interplays between scallop muscle proteins and soy proteins to form soluble composites

Food Funct., 2020, 11,3351-3360
DOI: 10.1039/C9FO03106E, Paper
Chao Wu, Jiamei Wang, Xiaokang Na, Zhenyu Wang, Xianbing Xu, Tao Wang
Scallop muscle proteins and soya proteins were packed into a composite with tunable internal, molecular arrangements of the secondary structures.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

cis 9, trans 11, but not trans 10, cis 12 CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice through activation of GPR120-[Ca2+]i and the MLCK signaling pathway

Food Funct., 2020, 11,3657-3667
DOI: 10.1039/D0FO00376J, Paper
Han Su, Weijie Zhao, Fenglin Zhang, Min Song, Fangfang Liu, Jisong Zheng, Mingfa Ling, Xiaohua Yang, Qiang Yang, Haiwen He, Lin Chen, Xumin Lai, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
In vitro and in vivo studies show that c9, t11-CLA, but not t10, c12-CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice via activation of GPR120-[Ca2+]i and the MLCK pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Dietary intake of Lycium ruthenicum Murray ethanol extract inhibits colonic inflammation in dextran sulfate sodium-induced murine experimental colitis

Food Funct., 2020, 11,2924-2937
DOI: 10.1039/D0FO00172D, Paper
Shuai Zong, Liu Yang, Hyun Jin Park, Jinglei Li
Lycium ruthenicum Murray extract protected experimental colitis by inhibiting pro-inflammatory cytokines production, inflammatory cell infiltration, inflammatory mediators activation and oxidative stress, and restored intestinal barrier integrity.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Correction: 5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes

Food Funct., 2020, 11,3749-3749
DOI: 10.1039/D0FO90012E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jie Liu, Yu Wang, Yiming Hao, Zongwei Wang, Zihui Yang, Ziyuan Wang, Jing Wang
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Lycium barbarum polysaccharides ameliorate intestinal barrier dysfunction and inflammation through the MLCK-MLC signaling pathway in Caco-2 cells

Food Funct., 2020, 11,3741-3748
DOI: 10.1039/D0FO00030B, Paper
Wei Li, Mingbo Gao, Ting Han
Impairment of the intestinal barrier often occurs in inflammatory bowel diseases, and pro-inflammatory factors play a vital role in the pathogenesis of intestinal diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

tert-Butyl-p-benzoquinone induces autophagy by inhibiting the Akt/mTOR signaling pathway in RAW 264.7 cells

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00281J, Paper
Xianghe Meng, Chaosheng Xia, Qin Ye, Xiaohua Nie
Autophagy mediate by p53/Akt/mTOR signaling was linked to overproduction of ROS by tert-butyl-p-benzoquinone.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Red ginseng protects against cisplatin-induced intestinal toxicity by inhibiting apoptosis and autophagy via the PI3K/AKT and MAPK signaling pathways

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00469C, Paper
Jun-jie Zhang, Jian-qiang Wang, Xing-yue Xu, Jia-yu Yang, Zi Wang, Shuang Jiang, Ying-ping Wang, Jing Zhang, Rui Zhang, Wei Li
Although growing evidence has shown that ginseng (Panax ginseng C.A. Meyer.) exerts strong protective and preventive effects on cisplatin-induced side effects, the ameliorative effects of ginseng on intestinal damage caused by cisplatin are unknown to date.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00427H, Paper
Xiao-Shan Long, Sen-Tai Liao, Peng Wen, Yu-Xiao Zou, Fan Liu, Wei-Zhi Shen, Teng-Gen Hu
Mulberry removed monosaccharides (FM) displayed better hypoglycemic activity than untreated mulberry (MP), which may be attributed the stronger effects of FM on activating PI3K/Akt and AMPK signaling pathways.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Jiaogulan tea (Gpostemma pentaphyllum) potentiates the antidiabetic effect of white tea via the AMPK and PI3K pathways in C57BL/6 mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00395F, Paper
Xiaoyan Xia, Jing Xu, Xude Wang, Hua Wang, Zhenchuan Lin, Keping Shao, LinLin Fang, Chenning Zhang, Yuqing Zhao
The use of plant-based beverages to interfere with the onset of diabetes may be a promising approach towards type 2 diabetes mellitus (T2DM).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02602A, Paper
Chu-Wen Li, Min-Zhen Deng, Zhi-Jie Gao, Yuan-Ye Dang, Guo-Dong Zheng, Xiu-Juan Yang, Ying-Xin Chao, Ye-Feng Cai, Xiao-Li Wu
The metabolite of ginsenosides, compound K improves memory and cognitive dysfunction in diabetes mellitus mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00711K, Paper
J. Q. Ma, Yun-Zhi Sun, Qing-Lei Ming, Zhi-Kai Tian, Yu-Jia Zhang, Chan-Min Liu
Gastrodin (GAS), the main phenolic glycoside extracted from Gastrodia elata Blume, exhibited potential renoprotective properties. Here we examined the protective effects of GAS against carbon tetrachloride (CCl4)-induced kidney inflammation and...
The content of this RSS Feed (c) The Royal Society of Chemistry




ay

With 30 days more to pay premium, make sure you don't let your policy lapse

Usually, general insurers give 30 days for health and 90 days for auto insurance policyholders to pay renewal premiums, even after the due date has passed




ay

Senior citizens may see spike in premiums in wake of Covid-19 crisis

Since they are more vulnerable, medical insurers may become more wary




ay

Lockdown 2.0: Govt extends renewal of health, motor policies till May 15

If the renewal of motor third party and health policy falls due between March 25 and May 3, the lockdown period, then policyholders can make the renewal payment on or before May 15




ay

10 ways to plan your finances right during the coronavirus crisis

Here's how to protect your finances during these difficult times and work on your short- and long-term financial goals efficiently




ay

Health premiums maybe paid in instalments: Regulator tells insurers

Option can be a permanent feature of health policies or can be a temporary relief for policyholders for 12 months




ay

Apple Updates iMac Family with Stunning New Retina Displays

Apple has updated the entire iMac family, bringing a new Retina 4K display to the 21.5-inch iMac for the first time and the Retina 5K display to every 27-inch iMac. The updated iMacs also feature more powerful processors and graphics, two Thunderbolt 2 ports, and new storage options that make the high-performance Fusion Drive even more affordable. Apple also introduced a new lineup of wireless accessories including the all-new Magic Keyboard, Magic Mouse 2, and Magic Trackpad 2. “From the first iMac to today, the spirit of iMac has never wavered — deliver the ultimate desktop experience with the latest technologies, gorgeous displays, and cutting-edge designs,” said Philip Schiller, Apple’s senior vice president of Worldwide Marketing. “These are the most stunning iMacs we’ve ever made. With our gorgeous new Retina displays, more powerful processors and graphics, and all-new Magic accessories, the new iMac continues to redefine the ultimate desktop experience.”




ay

Record-Breaking Holiday Season for the App Store

Customers around the world made this holiday season the biggest ever for the App Store, setting new records during the weeks of Christmas and New Year’s. In the two weeks ending January 3, customers spent over $1.1 billion on apps and in-app purchases, setting back-to-back weekly records for traffic and purchases. January 1 marked the biggest day in App Store history with customers spending over $144 million. “The App Store had a holiday season for the record books. We are excited that our customers downloaded and enjoyed so many incredible apps for iPhone, iPad, Mac, Apple Watch, and Apple TV, spending over $20 billion on the App Store last year alone,” said Philip Schiller, Apple’s senior vice president of Worldwide Marketing. “We’re grateful to all the developers who have created the most innovative and exciting apps in the world for our customers. We can’t wait for what’s to come in 2016.”




ay

Apple Introduces iPhone SE — the Most Powerful Phone with a 4-inch Display

Apple today introduced iPhone SE, the most powerful phone with a 4-inch display, in a compact aluminum design that has been updated with matte-chamfered edges, a color-matched stainless steel Apple logo, and four metallic finishes. iPhone SE offers the same 64-bit A9 chip offered in iPhone 6s and iPhone 6s. “iPhone SE is packed with a stunning 4-inch Retina display, advanced 64-bit A9 chip with M9 motion co-processor, longer battery life, 12-megapixel iSight camera with True Tone flash, Live Photos, 4K video, faster LTE and Wi-Fi, and Touch ID with Apple Pay. Everyone who wants a smaller phone is going to love iPhone SE,” said Philip Schiller, Apple’s senior vice president of Worldwide Marketing.




ay

The One Day: Justice Delivered Review

Slipshod direction and listless story produce a superfluous drama about how a judge turns into a murderer, notes Prasanna D Zore.




ay

The Panchayat review

'Even a hardcore nit-picker will struggle to find faults in this extraordinarily crafted television series that I rate as a must watch, an instant classic,' says Sukanya Verma.




ay

I take responsibility for the rebellion by MLAs: Kishore Upadhyay

Interview with Uttarakhand Pradesh Congress Committee President




ay

Why can't we just be friends, says Husain Haqqani

Interview with former Pakistan ambassador to the US




ay

Google announces company holiday on May 22 to deal with ‘virus burnout’

Google announces company holiday on May 22 to deal with ‘virus burnout’




ay

Don't hike fees, give parents more payment options: Maharashtra Education department

Don't hike fees, give parents more payment options: Maharashtra Education department




ay

Covid-19 lockdown: Delayed academic plans and uncertainty - anxiety grips CBSE class 12 students

Covid-19 lockdown: Delayed academic plans and uncertainty - anxiety grips CBSE class 12 students




ay

Mother's Day: Greetings, Photos, WhatsApp and Facebook Status

Mother's Day: Greetings, Photos, WhatsApp and Facebook Status




ay

Mother's Day special: How about buying your mother some jewellery in lockdown?

Mother's Day special: How about buying your mother some jewellery in lockdown?




ay

Wrinkles and tired skin? Your mom needs some DIY treatment this Mother's Day

Wrinkles and tired skin? Your mom needs some DIY treatment this Mother's Day




ay

Only these two Malayalam movies qualify for digital release

Only these two Malayalam movies qualify for digital release




ay

Here's how Payal Rajput feels about Kartikeya being cast for RX 100 instead of Vijay Deverakonda

Here's how Payal Rajput feels about Kartikeya being cast for RX 100 instead of Vijay Deverakonda




ay

Anu Emmanuel to pair up with Udhayanidhi in Magizh Thirumeni's film?

Anu Emmanuel to pair up with Udhayanidhi in Magizh Thirumeni's film?




ay

Ajay Gnanamuthu clarifies on Vikram's Cobra!

Ajay Gnanamuthu clarifies on Vikram's Cobra!




ay

Taylor Swift announces 'City of Lover' concert

Taylor Swift announces 'City of Lover' concert




ay

Important to keep young shuttlers motivated: Sanjay Mishra

Important to keep young shuttlers motivated: Sanjay Mishra




ay

Lockdown effect: Junior badminton coach says feel like a counsellor dealing with frustrated players

Lockdown effect: Junior badminton coach says feel like a counsellor dealing with frustrated players




ay

Tiger Woods, Phil Mickelson, Peyton Manning and Tom Brady showdown set for May 24

Tiger Woods, Phil Mickelson, Peyton Manning and Tom Brady showdown set for May 24




ay

Senior hockey players to undergo coaching course online amid lockdown

Senior hockey players to undergo coaching course online amid lockdown




ay

None more unbeatable than Novak Djokovic at his best, says Todd Martin

None more unbeatable than Novak Djokovic at his best, says Todd Martin




ay

Grand Slam tally should decide 'GOAT' debate, says Ivan Lendl

Grand Slam tally should decide 'GOAT' debate, says Ivan Lendl




ay

Chennai connection: Chennaiyin FC player Anirudh Thapa loves MS Dhoni's 'down to earth' attitude

Chennai connection: Chennaiyin FC player Anirudh Thapa loves MS Dhoni's 'down to earth' attitude




ay

One of world's oldest men marks 116th birthday in South Africa

One of world's oldest men marks 116th birthday in South Africa




ay

Coronavirus forces Russia to hold slimmed down Victory Day in blow to Putin - Times of India

Coronavirus forces Russia to hold slimmed down Victory Day in blow to Putin - Times of India