ita Why COVID-19 patients at the VA hospital in Spokane aren't counted as 'hospitalized' By www.inlander.com Published On :: Fri, 08 May 2020 15:20:19 -0700 If you go to check how many people are hospitalized with COVID-19 in Spokane, the Spokane County Regional Health District website will give you an answer. Right now, it lists eight people as currently hospitalized with COVID-19, and that number has been trending downward.… Full Article News/Local News
ita Process for producing biodiesel through lower molecular weight alcohol-targeted cavitation By www.freepatentsonline.com Published On :: Tue, 17 Mar 2015 08:00:00 EDT A method for producing fatty acid alkyl esters from biolipids through transesterification and/or esterification reactions uses a flow-through cavitation device for generating cavitation bubbles in a fluidic reaction medium. The fluidic medium is passed through sequential compartments in the cavitation device having varying diameters and inner surface features to create localized reductions in fluid pressure thus vaporizing volatile alcohols and creating an increased surface area and optimized conditions for the reaction to occur at the gas-liquid interface around the bubbles. Full Article
ita Using cavitation to increase oil separation By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT Methods and systems are provided that apply cavitation to a grain-based liquid medium processing stream of an oil separation process in order to achieve increased yields. Ultrasonic sources can be used in generating the cavitation. Typically, the oil processing system is a downstream process of an alcohol (such as ethanol) production facility utilizing a dry grind, a modified dry grind or a wet mill alcohol production process. Full Article
ita Bleed resistant, oil-extended olefin block copolymer composition with precipitated silica By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Disclosed are oil-extended olefin block copolymer compositions with precipitated silica. The precipitated silica reduces oil-bleed while maintaining composition softness. Full Article
ita Titanocenes, the use thereof, and N-substituted pyrroles By www.freepatentsonline.com Published On :: Tue, 16 Apr 1991 08:00:00 EDT Titanocenes containing two 5-membered cyclodienyl groups, for example cyclopentadienyl, and one or two 6-membered carbocyclic or 5- or 6-membered heterocyclic aromatic rings which are substituted by a fluorine atom in at least one of the two ortho-positions to the titanium-carbon bond and contain, as a further substituent, unsubstituted or substituted 1-pyrryl, are suitable as photoinitiators for radiation-induced polymerization of ethylenically unsaturated compounds. Full Article
ita Methods for forming lead zirconate titanate nanoparticles By www.freepatentsonline.com Published On :: Tue, 14 Apr 2015 08:00:00 EDT Methods for forming lead zirconate titanate (PZT) nanoparticles are provided. The PZT nanoparticles are formed from a precursor solution, comprising a source of lead, a source of titanium, a source of zirconium, and a mineralizer, that undergoes a hydrothermal process. The size and morphology of the PZT nanoparticles are controlled, in part, by the heating schedule used during the hydrothermal process. Full Article
ita Method and apparatus for detecting a parity error in a sequence of DQPSK symbols of a digital transmission system By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present disclosure relates to a method for detecting a parity error in a sequence of DQPSK symbols of a digital transmission system, comprising determining a first demodulated symbol r1; determining a second demodulated symbol r2; determining a first parity symbol p1; determining a second parity symbol p2; determining a super-parity symbol q1; and detecting a parity error in the sequence of DQPSK symbols by comparing a combination of the first parity symbol p1 and the second parity symbol p2 against the super-parity symbol q1, wherein a parity between two DQPSK symbols describes a phase difference between the two DQPSK symbols. Full Article
ita Container and method for facilitating disposal of unused pharmaceutical product By www.freepatentsonline.com Published On :: Tue, 14 Apr 2015 08:00:00 EDT Containers and methods for disposing unused pharmaceutical product are disclosed. Each container (100, 200, 300) may include a container body (104, 204, 304) with an internal chamber (116, 216, 316) for storing pharmaceutical product, along with a cover (124, 224, 324) for selectively limiting access to the chamber (116, 216, 316). An encapsulation component (128, 228, 328) may be selectively disposable within the chamber (116, 216, 316), and may be operable to encapsulate the pharmaceutical product within the container (100, 200, 300). For instance, the encapsulation component (128, 228, 328) may melt and/or flow into contact with the pharmaceutical product and thereafter solidify to encapsulate the pharmaceutical product. The encapsulation component (128, 228, 328) may melt and thereafter solidify between the cover (124, 224, 324) and shell (104, 204, 304) to limit removal of the cover (124, 224, 324) from the shell (104, 204, 304). Full Article
ita Phase-to-amplitude converter for direct digital synthesizer (DDS) with reduced AND and reconstructed ADD logic arrays By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A sine wave generator for a Direct Digital Synthesizer (DDS) converts a digital phase input into a digital sine wave output. Sine values and slopes are stored in read-only memory (ROM) for coarse upper phase bits in a first quadrant. A quadrant folder and phase splitter reflects and inverts values from the first quadrant to generate amplitudes for all four quadrants. Each sine value and slope is stored for a range of lower phase bits. A Delta bit separates upper and lower phase bits. Delta conditionally inverts the lower phase bits, the sine value, and the final polarity. A reduced AND logic array multiplies the slope by the conditionally inverted lower phase bits. A reconstructed ADD logic array then adds the conditionally inverted sine value. The conditionally inverted polarity is added to generate the final sine value. Sine generation logic is streamlined with conditional inversion based on the Delta bit. Full Article
ita Method to facilitate fast context switching for partial and extended path extension to remote expanders By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method, apparatus, and system for switching from an existing target end device to a next target end device in a multi-expander storage topology by using Fast Context Switching. The method enhances Fast Context Switching by allowing Fast Context Switching to reuse or extend part of an existing connection path to an end device directly attached to a remote expander. The method can include reusing or extending at least a partial path of an established connection between an initiator and the existing target end device for a connection between the initiator and the next target end device, whereby the existing target end device and the next target end device are locally attached to different expanders. Full Article
ita Method and apparatus for generating metadata for digital content By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A method and an apparatus for generating metadata for digital content are described, which allow to review the generated metadata already in course of ongoing generation of metadata. The metadata generation is split into a plurality of processing tasks, which are allocated to two or more processing nodes. The metadata generated by the two or more processing nodes is gathered and visualized on an output unit. Full Article
ita Reactor and agitator useful in a process for making 1-chloro-3,3,3-trifluoropropene By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT Disclosed is a reactor and agitator useful in a high pressure process for making 1-chloro-3,3,3-trifluoropropene (1233zd) from the reaction of 1,1,1,3,3-pentachloropropane (240fa) and HF, wherein the agitator includes one or more of the following design improvements: (a) double mechanical seals with an inert barrier fluid or a single seal;(b) ceramics on the rotating faces of the seal;(c) ceramics on the static faces of seal;(d) wetted o-rings constructed of spring-energized Teflon and PTFE wedge or dynamic o-ring designs; and(e) wetted metal surfaces of the agitator constructed of a corrosion resistant alloy. Full Article
ita Implementation of multi-tasking on a digital signal processor with a hardware stack By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The disclosure relates to the implementation of multi-tasking on a digital signal processor. Blocking functions are arranged such that they do not make use of a processor's hardware stack. Respective function calls are replaced with a piece of inline assembly code, which instead performs a branch to the correct routine for carrying out said function. If a blocking condition of the blocking function is encountered, a task switch can be done to resume another task. Whilst the hardware stack is not used when a task switch might have to occur, mixed-up contents of the hardware stack among function calls performed by different tasks are avoided. Full Article
ita Dynamic energy savings for digital signal processor modules using plural energy savings states By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT In an example embodiment, there is described herein an apparatus comprising an interface for communicating with a plurality of digital signal processors and logic operable to send and receive data via the interface. The logic is configured to determine a first set of digital signal processors to be maintained in a ready state, a second set of digital signal processors to be maintained in a first energy saving state, and a third set of digital signal processors to be maintained in a second energy saving state. Full Article
ita Framework for facilitating implementation of multi-tenant SaaS architecture By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A framework for implementing multitenant architecture is provided. The framework comprises a framework services module which is configured to provide framework services that facilitate abstraction of Software-as-a-Service (SaaS) services and crosscutting services for a Greenfield application and a non SaaS based web application. Further the abstraction results in a SaaS based multitenant web application. The framework further comprises a runtime module configured to automatically integrate and consume the framework services and APIs to facilitate monitoring and controlling of features associated with the SaaS based multitenant web application. The framework further comprises a metadata services module configured to provide a plurality of metadata services to facilitate abstraction of storage structure of metadata associated with the framework and act as APIs for managing the metadata. The framework further comprises a role based administration module that facilitates management of the metadata through a tenant administrator and a product administrator. Full Article
ita Firmware update method and apparatus of set-top box for digital broadcast system By www.freepatentsonline.com Published On :: Tue, 03 Nov 2015 08:00:00 EST A firmware update method and apparatus of a set-top box for a digital broadcast system is provided. A firmware update method of a set-top box for a digital broadcast system includes determining whether a newly received Code Version Table (CVT) following a public CVT which has been previously received and stored is the public CVT or a filtering CVT; and updating, when the newly received CVG is the filtering CVT, the firmware of the set-top box with a filtering firmware indicated by the filtering CVT. Full Article
ita Data mining in a digital map database to identify blind intersections along roads and enabling precautionary actions in a vehicle By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Disclosed is a feature for a vehicle that enables taking precautionary actions in response to conditions on the road network around or ahead of the vehicle, in particular, a blind intersection along a section of road. A database that represents the road network is used to determine locations where a blind intersection is located along a section of road. Then, precautionary action data is added to the database to indicate a location at which a precautionary action is to be taken about the blind intersection located along the section of road. A precautionary action system installed in a vehicle uses this database, or a database derived therefrom, in combination with a positioning system to determine when the vehicle is at a location that corresponds to the location of a precautionary action. When the vehicle is at such a location, a precautionary action is taken by a vehicle system as the vehicle is approaching a blind intersection. Full Article
ita Method for displaying suitability of future waypoint locations By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method for illustrating an aircraft flight plan comprising at least one waypoint on a flight display of a flight deck of an aircraft, where the method may include displaying on the flight display of the flight deck some type of display indicia that indicates the suitability of locations for future waypoints. Full Article
ita Digital circuit verification monitor By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT A method, a system and a computer readable medium for providing information relating to a verification of a digital circuit. The verification may be formal verification and comprise formally verifying that a plurality of formal properties is valid for a representation of the digital circuit. The method comprises replacing at least a first input value relating to the representation of the digital circuit by a first free variable, determining if at least one of the plurality of formal properties is valid or invalid after replacing the first input value by the first variable and indicating if the at least one of the plurality of formal property is valid or invalid. The use of a free or open variable that has not determined value can be directly in the description or representation of the digital circuit. It is not necessary to insert errors or to apply an error model. Full Article
ita System and method for automated simulator assertion synthesis and digital equivalence checking By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT A system, method, and computer program product for automatically generating equivalent assertions in different forms for different verification tools, which may be analog or digital. A user submits a set of logic assertions that, if unclocked, are converted to clocked assertions by generating and skewing clocks to ensure simulator uniformity. A stimulus is generated, perhaps at random, or input. A test bench is either input or synthesized. For each verification tool, the test bench is simulated and simulation results are captured. An assertion status difference engine evaluates result differences between the verification tools, and identifies and outputs differences indicating a significant inconsistency. Errors in verification tool implementation and user assertion coding can be detected. The simulators used may include SPICE and Verilog, or any other simulators that differ in type, simulation algorithm, input format, or vendor implementation. Full Article
ita Method of optimizing capacitive couplings in high-capacitance nets in simulation of post-layout circuits By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT A method of asymmetric asynchronous decoupling of capacitors in an integrated circuit design is provided for faster simulation by circuit simulators, e.g. FastSPICE circuit simulators. This method includes removing a coupling capacitor from a list, which includes coupling capacitors that capacitively couple two nets in the design. The two nets have capacitances C1 and C2, and at least one of capacitances C1 and C2 exceeds a threshold. The coupling capacitor has capacitance Cc. When coupling capacitance Cc is low and only one of capacitances C1 and C2 has a low capacitance, then a forward capacitance can be used at whichever of the two nets has the low capacitance and a lump capacitance can be used at the other net for simulation. When coupling capacitance Cc is low and both of capacitances C1 and C2 have high capacitances, then lump capacitances can be used at the two nets for the simulation. Full Article
ita Email administration for rendering email on a digital audio player By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Methods, systems, and computer program products are provided for email administration for rendering email on a digital audio player. Embodiments include retrieving an email message; extracting text from the email message; creating a media file; and storing the extracted text of the email message as metadata associated with the media file. Embodiments may also include storing the media file on a digital audio player and displaying the metadata describing the media file, the metadata containing the extracted text of the email message. Full Article
ita Method and system for facilitating communications for a user transaction By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Current human-to-machine interfaces enable users to interact with a company's database and enter into a series of transactions (e.g., purchasing products/services and paying bills). Each transaction may require several operations or stages requiring user input or interaction. Some systems enable a user to enter a voice input parameter providing multiple operations of instruction (e.g., single natural language command). However, users of such a system do not know what types of commands the system is capable of accepting. Embodiments of the present invention facilitate communications for user transactions by determining a user's goal transaction and presenting a visual representation of a voice input parameter for the goal transaction. The use of visual representations notifies the user of the system's capability of accepting single natural language commands and the types of commands the system is capable of accepting, thereby enabling a user to complete a transaction in a shorter period of time. Full Article
ita Interfaces for digital media processing By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT APIs discussed herein promote efficient and timely interoperability between hardware and software components within the media processing pipelines of media content players. A PhysMemDataStructure API facilitates a hardware component's direct access to information within a memory used by a software component, to enable the hardware component to use direct memory access techniques to obtain the contents of the memory, instead of using processor cycles to execute copy commands. The PhysMemDataStructure API exposes one or more fields of data structures associated with units of media content stored in a memory used by a software component, and the exposed fields store information about the physical properties of the memory locations of the units of media content. SyncHelper APIs are used for obtaining information from, and passing information to, hardware components, which information is used to adjust the hardware components' timing for preparing media samples of synchronously-presentable media content streams. Full Article
ita System and method for identifying exploitable weak points in a network By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The system and method described herein may leverage passive and active vulnerability discovery to identify network addresses and open ports associated with connections that one or more passive scanners observed in a network and current connections that one or more active scanners enumerated in the network. The observed and enumerated current connections may be used to model trust relationships and identify exploitable weak points in the network, wherein the exploitable weak points may include hosts that have exploitable services, exploitable client software, and/or exploitable trust relationships. Furthermore, an attack that uses the modeled trust relationships to target the exploitable weak points on a selected host in the network may be simulated to enumerate remote network addresses that could compromise the network and determine an exploitation path that the enumerated remote network addresses could use to compromise the network. Full Article
ita System and method for providing digital messaging services By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An exemplary embodiment of the invention relates to a system and method for providing digital messaging services received from multiple sources over a communications network. The system includes a client system, including a display screen coupled to a communications link; a workstation including a web browser, a memory, and a processor, said workstation coupled to said communications link; a hosting system, including a graphics server, a content server, and a scheduling server, each in communication with each other via a communications link; and a workstation and data storage device coupled to the communications link; and a data storage device for storing data utilized by said hosting system. The client system requests and receives digital messaging services from said hosting system under a subscription agreement. Digital messaging services include advertisements procured from said client system, and one or more local content providers, national advertisers, local advertisers, corporate marketing groups, and advertising agencies. Interactive digital messaging services are also available through the present invention. A user accesses these services via a variety of input devices; such as a bar code scanner, a wireless telephone or personal digital assistant, a kiosk with touch screen design, microphone, or other similar input device. Full Article
ita Facilitating context delivery during communication sessions By www.freepatentsonline.com Published On :: Tue, 07 Jul 2015 08:00:00 EDT An approach is disclosed that facilitates context delivery during communication sessions. The approach may be implemented in a computer infrastructure having computer executable code tangibly embodied on a computer readable storage medium having programming instructions operable to: render at least one service to a user device through a communication session; collect information of the communication session; and send the information of the communication session to a service provider when a call is setup between the user device and the service provider. The service provider renders the information of the communication session for viewing by the service provider. Full Article
ita Method for controlling content and digital device using the same By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method and device for controlling content that includes plural display pages in a sequence, the method including: displaying a current page included in the content; receiving a user input to or above a display screen of the display unit for changing from the current page to another page of the content; extracting fingerprint information from the user input; determining whether the content of the another page is or is not accessible based on the extracted fingerprint information; if all of the content of the another page is determined to be accessible based on the extracted fingerprint information, displaying the another page; and if any of the content of the another page is determined not to be accessible based on the extracted fingerprint information, displaying a page following the current page without displaying content of the another page that was determined not to be accessible. Full Article
ita Method and system for facilitating remote medical diagnosis and consultation By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system for facilitating remote medical diagnosis and consultation of heart disease for a patient, the system comprising: a diagnostic device for performing Electrocardiography on the patient, a network device in communication with the diagnostic device via wired or wireless communication links, a software program pre-installed in the network device, a server located remotely, wherein during operation, the patient activates the diagnostic device which will perform Electrocardiography on the patient, the diagnostic device receives diagnostic data and transmits the diagnostic data to the network device, the software program transmit the diagnostic data to over a network to a server which a physician have access to, and based on the diagnostic data gathered by the server and some additional medical data, the physician can review the patient's health condition and offer an appropriate feedback and diagnosis for the patient. Full Article
ita Catalytic synthesis of vitamin A intermediate By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention relates to a process of production of a compound, which is useful as an intermediate (building block) in organic synthesis, especially in the synthesis of vitamin A or β-carotene and derivatives thereof, e.g. canthaxanthin, astaxanthin or zeaxanthin. Full Article
ita Crystallization of (20R) and (20S) analogs of 2-methylene-19-nor-24-dimethyl-1α,25-dihydroxyvitamin D3 By www.freepatentsonline.com Published On :: Tue, 11 Nov 2014 08:00:00 EST Disclosed are methods of purifying (20R) and (20S) analogs of 2-methylene-19-nor-22-dimethyl-1α,25-dihydroxyvitamin D3 to obtain the (20R) and (20S) analogs in crystalline form. The method includes the steps of preparing a solvent of either diethyl ether or a mixture of 2-propanol and hexane, dissolving a product containing the (20R) and (20S) analog to be purified in the solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals. Full Article
ita Oral dosage form of 25-hydroxyvitamin D By www.freepatentsonline.com Published On :: Tue, 09 Dec 2014 08:00:00 EST Methods and compositions for treating 25-hydroxyvitamin D insufficiency and deficiency in a patient are described herein. The method includes orally administering to the patient a delayed, sustained release formulation including a first ingredient selected from the group consisting of 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, or a combination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3, or it includes gradually administering to the patient a sterile intravenous formulation including a first ingredient selected from the group consisting of 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, or a combination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3. Full Article
ita Low-calcemic 16,23-diene 25-oxime analogs of 1α,25-dihydroxy vitamin D3 By www.freepatentsonline.com Published On :: Tue, 09 Dec 2014 08:00:00 EST The present invention provides novel 16,23-diene 25-oxime ether analogs of 1,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the novel compound of the invention are useful for treating diseases which benefit from a modulation of the levels of 1,25-dihydroxy vitamin D3, for example, cell-proliferative disorders. Full Article
ita Crystallization of (20R)-2-methylene-19-nor-24-difluoro-1α,25-dihydroxyvitamin D3 By www.freepatentsonline.com Published On :: Tue, 27 Jan 2015 08:00:00 EST Disclosed are methods of purifying the compound (20R)-2-methylene-19-nor-24-difluoro-1α,25-dihydroxyvitamin D3 to obtain the compound in crystalline form. The methods typically include the steps of dissolving a product containing the compound in a solvent comprising hexane and 2-propanol, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals. Full Article
ita N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs and their uses By www.freepatentsonline.com Published On :: Tue, 24 Mar 2015 08:00:00 EDT This invention discloses N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs, and specifically N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-1α-hydroxyvitamin D3 and pharmaceutical uses therefor. This compound exhibits relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent especially for the treatment or prevention of leukemia, colon cancer, breast cancer, skin cancer or prostate cancer. Full Article
ita 3-desoxy-2-methylene-19-nor-vitamin D analogs and their uses By www.freepatentsonline.com Published On :: Tue, 31 Mar 2015 08:00:00 EDT This invention discloses 3-desoxy-2-methylene-19-nor-vitamin D analogs, and specifically (20S)-3-desoxy-2-methylene-1α,25-dihydroxy-19-nor-vitamin D3 and (20R)-3-desoxy-2-methylene-1α,25-dihydroxy-19-nor-vitamin D3 as well as pharmaceutical uses therefor. These compounds exhibit relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to monocytes thus evidencing use as anti-cancer agents especially for the treatment or prevention of osteosarcoma, leukemia, colon cancer, breast cancer, skin cancer or prostate cancer. These compounds also exhibit relatively high calcemic activity evidencing use in the treatment of bone diseases. Full Article
ita 23-yne-vitamin D3 derivative By www.freepatentsonline.com Published On :: Tue, 14 Apr 2015 08:00:00 EDT To provide a novel vitamin D3 derivative useful as a therapeutic agent for osteoporosis. Provided is a vitamin D3 derivative represented by the following formula (1) or a medicinally acceptable solvate thereof: wherein R1 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkylcarbonyloxyalkyl group with each alkyl having 1 to 6 carbon atoms, or an arylcarbonyloxyalkyl group with the aryl having 6 to 10 carbon atoms and the alkyl having 1 to 6 carbon atoms; R2 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms or, together with the other R2 and the carbon atom to which they are bound to, may form a cyclic alkyl group having 3 to 6 carbon atoms; R3 represents an alkyl group having 1 to 6 carbon atoms or, together with the other R3 and the carbon atom to which they are bound to, may form a cyclic alkyl group having 3 to 6 carbon atoms; X represents an oxygen atom or a methylene group; and n represents an integer of 1 or 2. Full Article
ita Vitamin D receptor modulators with partial agonist activity By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The present invention provides a compound which functions as a selective vitamin D receptor modulator and has action-selectivity or tissue-selectivity such that it does not induce hypercalcemia but causes other effects. There is provided a compound represented by formula (I), a solvate thereof or a prodrug thereof. wherein m and n each independently represent 1 or 0;R represents a hydrogen atom or an alkyl group;Y represents an ethane-1,1-diyl group or an ethyne-1,2-diyl group; andZ1 represents a hydrogen atom and Z2 represents a hydroxyalkoxy group, orZ1 and Z2 jointly form a methylene group. Full Article
ita Crystallization of (20R) 19-nor-24-difluoro-1α,25-dihydroxyvitamin D3 By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Disclosed are methods of purifying the compound (20R)-19-nor-24-difluoro-1α,25-dihydroxyvitamin D3 to obtain the compound in crystalline form. The methods typically include the steps of dissolving a product containing the compound in a solvent comprising hexane and 2-propanol, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals. Full Article
ita Digital flowmeter By www.freepatentsonline.com Published On :: Tue, 14 Jul 2015 08:00:00 EDT A control and measurement system for a coriolis flowmeter having a flowtube, a driver adapted to vibrate the flowtube, and a pair of sensors adapted to generate signals indicative of movement of the flowtube when it is being vibrated by the driver, wherein the sensors are positioned relative to one another so the signals from the sensors are indicative of a mass flow rate of fluid through the flowtube. A digital drive signal generator is adapted to generate a variable digital drive signal for controlling operation of the driver. The digital drive signal generator can be adapted to cause the driver to resist motion of the flowtube during a first time period and amplify motion of the flowtube during a second time period. The digital drive signal generator can also be adapted to initiate motion of the flowtube by sending one or more square wave signals to the driver. Full Article
ita Digital flowmeter By www.freepatentsonline.com Published On :: Tue, 28 Jul 2015 08:00:00 EDT A control and measurement system for a coriolis flowmeter having a flowtube, a driver adapted to vibrate the flowtube, and a pair of sensors adapted to generate signals indicative of movement of the flowtube when it is being vibrated by the driver, wherein the sensors are positioned relative to one another so the signals from the sensors are indicative of a mass flow rate of fluid through the flowtube. A digital drive signal generator is adapted to generate a variable digital drive signal for controlling operation of the driver. The digital drive signal generator can be adapted to cause the driver to resist motion of the flowtube during a first time period and amplify motion of the flowtube during a second time period. The digital drive signal generator can also be adapted to initiate motion of the flowtube by sending one or more square wave signals to the driver. Full Article
ita Polysiloxane-modified polyhydroxy polyurethane resin, method for producing same, heat-sensitive recording material using the resin, imitation leather, thermoplastic polyolefin resin skin material, material for weather strip, and weather strip By www.freepatentsonline.com Published On :: Tue, 10 Feb 2015 08:00:00 EST Disclosed are a polysiloxane-modified polyhydroxy polyurethane resin characterized by being derived from a reaction between a 5-membered cyclic carbonate polysiloxane compound represented by the below-described formula (1) and an amine compound, and its production process; and a resin composition, thermal recording medium, imitation leather, thermoplastic polyolefin resin skin material, weather strip material, and weather strip, all of which make use of the resin. wherein A means Full Article
ita Method and apparatus for quantitative nerve localization By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method for localizing a needle to a nerve, the method comprising: using the needle to electrically stimulate the nerve, with a known current intensity, so as to evoke a nerve response;detecting the nerve response;analyzing the detected nerve response so as to identify at least one attribute of the same; andconfirming that the needle is in the immediate proximity of the nerve based upon known current intensity and at least one identified attribute of the detected nerve response. Full Article
ita Ultrasound operation apparatus, cavitation control method, and ultrasound transducer control method By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT An ultrasound operation apparatus comprises: an ultrasound transducer; a driving section that drives the ultrasound transducer by a drive signal; a probe having a proximal end section provided with the ultrasound transducer and a distal end section to which ultrasound oscillation is transmitted, the probe performing a treatment on a living tissue using ultrasound oscillation at the distal end section; a detecting section that detects, from a drive signal, a physical quantity which varies due to cavitation generated by ultrasound oscillation of the distal end section; and an output control section that controls an output of the driving section in accordance with the detected physical quantity. Full Article
ita Method for manufacturing aluminum-titanate-based ceramic honeycomb structure By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT A method for manufacturing a ceramic honeycomb structure includes kneading titania particles, alumina particles and a binder ingredient such that raw material paste including the titania particles, alumina particles and binder ingredient is prepared, forming a body made of the raw material paste and having a honeycomb structure such that the body has the honeycomb structure having multiple through-holes extending in the longitudinal direction of the body and multiple partition portions formed between the through-holes, applying sealant composition including aluminum hydroxide particles, talc particles, kaolin particles, water and organic binder to either end of each through-hole of the body in the longitudinal direction such that the honeycomb structure of the body has each through-hole sealed at one end, and sintering the body made of the raw material paste and having the honeycomb structure sealed by the sealant composition such that a ceramic body having the honeycomb structure is formed. Full Article
ita Unitary elastic mold and cutter combination By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A unitary elastic mold and cutter combination configured to mold and cut moldable material is disclosed herein. The mold and cutter combination comprises an elastic mold cavity having an elastic bottom wall with an embossed inner surface and an elastic sidewall extending from and unitary with a perimeter of the bottom wall. An elastic cutting blade extends from and is unitary with the sidewall of the mold cavity and is configured to cut moldable material and maintain a substantially consistent perimeter upon cutting. The cutting blade comprises a cutting edge disposed between an inner cutting blade surface and an outer cutting blade surface. The mold and cutter combination may have an elasticity sufficient to release molded material therefrom by hand stretching, wherein the cutting edge, inner cutting blade surface, and the inner surface of the sidewall of the mold cavity are stretched by an amount sufficient to release the molded material. Full Article
ita Harness attachment for a guitar By www.freepatentsonline.com Published On :: Tue, 26 Jun 2001 08:00:00 EDT A harness attachment to shoulder strap harness for holding a guitar in the front of the player which is attached to the left fret end and right strumming end of the guitar. The present invention has an additional right srumming end attachment which mounts over the right strumming end attachment of the shoulder strap harness. The attachment of the present invention includes a lower mounting member and an upper adjustable loop member movably attachable to the player's right hip area in a number of embodiments. Full Article
ita Modular automated assistive guitar By www.freepatentsonline.com Published On :: Tue, 23 Oct 2007 08:00:00 EDT A modular automated assistive guitar is described comprising a base assembly, a pick assembly, a strumming mechanism and a fretting mechanism which, in combination with a standard guitar or similar stringed musical instrument (e.g., banjo, steel guitar, ukulele), forms a musical device that can be played by an individual with a range of independence, cognitive and physical abilities. The base assembly accepts, positions, and secures a standard guitar. The pick assembly includes quick attach and spring-loaded features for attaching and detaching picks, in addition to flexibility for smooth interaction with the guitar strings. The strumming mechanism provides cyclic motion and speed control to create pleasant and variable rhythm from the mounted guitar. The fretting mechanism allows a user to change chords and tone. An unmodified, traditional guitar is preferably used in the musical device. The guitar is easily interchangeable with another guitar or other stringed instrument, at the convenience of the user. The modular automated assistive musical device, with or without the guitar, is compact, light, portable, and easily adjustable to different individual's needs, motor skills, and dexterity. Full Article
ita Method and an apparatus/universal combine for agitation of liquids By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A method of mixing together liquids or liquid/solid combinations, and mixing apparatus/universal combine utilizing a vertical spinning container or vessel having a rib, or a cross rib in its bottom wall. The container is spun about a vertical axis with no wobbling component to the motion. Meshed elements are used for high shear mixing. Start/stop routines, and variable acceleration/speed values are used, to facilitate complete mixing. Use of ‘impeller’ blade stirrers is completely eliminated. Full Article
ita Tank agitation system with moveable shaft support By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT An apparatus for containing and mixing a load of liquids and solids is disclosed. The apparatus includes an elongated tank, which includes a lower portion and an upper portion. The apparatus further includes an elongated rotatable shaft within the tank. At least one blade is connected to the shaft and is configured to mix the liquids and solids when the shaft is rotated. The apparatus also includes a shaft support configured for maintaining the shaft in a rotatable manner within the tank. The shaft support is selectively moveable in a manner permitting the shaft to move in an upward direction from the lower portion toward the upper portion, and in a downward direction from the upper portion toward the lower portion. An is contained with the tank for moving the shaft support in the upward direction and in the downward direction. Full Article