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The first copper(II) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00006J, Paper
Sebastiano Masuri, Enzo Cadoni, Maria Grazia Cabiddu, Francesco Isaia, Maria Giovanna Demuru, Lukáš Moráň, David Buček, Petr Vaňhara, Josef Havel, Tiziana Pivetta
The novel complex Cu(phen)2(salubrinal)(ClO4)2 shows high free radical scavenging activity and good cytotoxic activity and induces cell death through ER-stress.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Testing with combined biopsy method improves prostate cancer diagnosis in NCI study

Testing for prostate cancer with a combined biopsy method led to more accurate diagnosis and prediction of the course of the disease in an NCI study. The method is poised to reduce the risk of prostate cancer overtreatment and undertreatment.




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[ASAP] Fragrant Venezuelaenes A and B with A 5–5–6–7 Tetracyclic Skeleton: Discovery, Biosynthesis, and Mechanisms of Central Catalysts

ACS Catalysis
DOI: 10.1021/acscatal.0c01575




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Mazumdar-Shaw recognised among world's top 20 inspirational leaders in Biopharma

Biocon Executive Chairperson Kiran Mazumdar-Shaw has been recognised for her contribution to the world of medicine as an entrepreneur and innovative business leader, the Bengaluru-headquartered biopharmaceuticals company said in a statement.




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Biocon gets establishment inspection report from USFDA for Bengaluru plant

The EIR has been closed with a voluntary action indicated (VAI) classification for the observations, it added. As per the USFDA, a VAI means that objectionable conditions or practices were found, but the agency is not prepared to take or recommend any administrative or regulatory action.




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Bharat Bio leads CSIR project to develop human antibodies

This programme brings together academia — National Centre for Cell Science, Indian Institute of Technology, Indore, and industry – PredOmix Technologies and Bharat Biotech, in a collaborative mode for a public health emergency.




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The Red Countess: Select Autobiographical and Fictional Writing of Hermynia Zur Mühlen (1883-1951).

Online Resource




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Science Podcast - Biomechanics of fruitflies on the wing and a news roundup (11 April 2014)

Fruitflies take evasive action; roundup of daily news with David Grimm.




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The home microbiome and a news roundup (29 August 2014)

Sharing microbes around the house; roundup of daily news.




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Scaling up a biofuel and a news roundup (5 Sep 2014)

Bringing cellulosic ethanol to market; roundup of daily news.




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Genes and the human microbiome and a news roundup

Seth Bordenstein discusses how our genes affect the composition of our microbiome, influencing our health, and David Grimm talks with Sarah Crespi about the origins of the Basque language, the benefits of being raised in a barn, and how some flying ants lost their wings. Hosted by Susanne Bard. [Image credit: Decaseconds/CC BY-NC 2.0, via flickr




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The origins of biodiversity in the Amazon and a daily news roundup

Lizzie Wade discusses whether the amazing biodiversity of the Amazon Basin was the result of massive flooding, or the uplift of the Andes mountain range. David Grimm talks about microbes aboard the International Space Station, the fate of juvenile giant ground sloths during the Pleistocene, and singing classes as social glue. Hosted by Susanne Bard. [Img: ©Jason Houston]




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Bioengineering functional vocal cords and a daily news roundup

Jennifer Long explains how scientists have engineered human vocal cords; Catherine Matacic talks about vanquishing a deadly amphibian fungus, pigeons that spot cancer, and more. Hosted by Susanne Bard. [Img: Jaime Bosch MNCN-CSIC]




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How our gut microbiota change as we age and a daily news roundup

Paul O'Toole discusses what happens to our gut microbes as we age; David Grimm talks about competent grandmas, our tilted moon, and gender in the brain. Hosted by Susanne Bard. [Img: Dhinakaran Gajavarathan CC BY 2.0, via flickr]




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Podcast: Bionic leaves that make fuel, digging into dog domestication, and wars recorded in coral

Listen to stories on new evidence for double dog domestication, what traces of mercury in coral can tell us about local wars, and an update to a classic adaptation story, with online news editor David Grimm.   Brendan Colón talks about a bionic leaf system that captures light and carbon and converts it to several different types of fuels with host Sarah Crespi.   [Image: Andy Phillips/Flickr/CC BY-ND 2.0/Music: Jeffrey Cook]




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Podcast: The archaeology of democracy, new additions to the uncanny valley, and the discovery of ant-ibiotics

This week, what bear-mounted cameras can tell us about their caribou-hunting habits, ants that mix up their own medicine, and feeling alienated by emotional robots with Online News Editor David Grimm. And Lizzie Wade joins Sarah Crespi to discuss new thinking on the origins of democracy outside of Europe, based on archeological sites in Mexico. Listen to previous podcasts. Download the show transcript. Transcripts courtesy of Scribie.com. [Image: rpbirdman/iStockphoto; Music: Jeffrey Cook]




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The biology of color, a database of industrial espionage, and a link between prions and diabetes

This week we hear stories on diagnosing Alzheimer’s disease in chimps, a potential new pathway to diabetes—through prions—and what a database of industrial espionage says about the economics of spying with Online News Editors David Grimm and Catherine Matacic. Sarah Crespi talks to Innes Cuthill about how the biology of color intersects with behavior, development, and vision. And Mary Soon Lee joins to share some of her chemistry haiku—one poem for each element in the periodic table. Listen to previous podcasts. [Image: Zoltan Tasi/Unsplash; Music: Jeffrey Cook]




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What hunter-gatherer gut microbiomes have that we don’t, and breaking the emoji code

Sarah Crespi talks to Sam Smits about how our microbial passengers differ from one culture to the next—are we losing diversity and the ability to fight chronic disease? For our books segment, Jen Golbeck talks with Vyvyan Evans about his book The Emoji Code: The Linguistics Behind Smiley Faces and Scaredy Cats. Listen to previous podcasts. [Image: Woodlouse/Flickr; Music: Jeffrey Cook]




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Treating the microbiome, and a gene that induces sleep

Orla Smith, editor of Science Translational Medicine joins host Sarah Crespi to talk about what has changed in the past 10 years of microbiome research, what’s getting close to being useful in treatment, and how strong, exactly, the research is behind those probiotic yogurts. When you’re sick, sleeping is restorative—it helps your body recover from nasty infections. Meagan Cantwell speaks with Amita Sehgal, professor of neuroscience at the University of Pennsylvania and an investigator at Howard Hughes Medical Institute in Chevy Chase, Maryland, about the process of discovering a gene in fruit flies that links sleep and immune function. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Music: Jeffrey Cook]




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Where our microbiome came from, and how our farming and hunting ancestors transformed the world

Micro-organisms live inside everything from the human gut to coral—but where do they come from? Host Meagan Cantwell talks to Staff Writer Elizabeth Pennisi about the first comprehensive survey of microbes in Hawaii’s Waimea Valley, which revealed that plants and animals get their unique microbiomes from organisms below them in the food chain or the wider environment. Going global, Meagan then speaks with Erle Ellis, professor of geography and environmental science at the University of Maryland, Baltimore County, about a project that aggregated the expertise of more than 250 archaeologists to map human land use over the past 10,000 years. This detailed map will help fine-tune climate models. This week’s episode was edited by Podigy. Ads on this show: Science Sessions Podcast; Kroger Download a transcript (PDF)  Listen to previous podcasts. About the Science Podcast [Image: Chris Couderc/Flickr; Music: Jeffrey Cook]




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Science’s leading role in the restoration of Notre Dame, and the surprising biology behind how our body develops its tough skin

On this week’s show, freelance writer Christa Lesté-Lasserre talks with host Sarah Crespi about the scientists working on the restoration of Notre Dame, from testing the changing weight of wet limestone, to how to remove lead contamination from four-story stained glass windows. As the emergency phase of work winds down, scientists are also starting to use the lull in tourist activity to investigate the mysteries of the cathedral’s construction. Also this week, Felipe Quiroz, an assistant professor in the biomedical engineering department at the Georgia Institute of Technology and Emory University, talks with Sarah about his paper on the cellular mechanism of liquid-liquid phase separation in the formation of the tough outer layer of the skin. Liquid-liquid phase separation is when two liquids “demix,” or separate, like oil and water. In cells, this process created membraneless organelles that are just now starting to be understood. In this work, Quiroz and colleagues create a sensor for phase separation in the cell that works in living tissue, and show how phase separation is tied to the formation of the outer layers of skin in mice. Read the related Insight. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: r. nial bradshaw/Flickr; Music: Jeffrey Cook]




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Does coronavirus spread through the air, and the biology of anorexia

On this week’s show, Staff Writer Robert Service talks with host Sarah Crespi about a new National Academy of Sciences report that suggests the novel coronavirus can go airborne, the evidence for this idea, and what this means for the mask-wearing debate. See all of our News coverage of the pandemic here. See all of our Research and Editorials here. Also this week, Staff Writer Jennifer Couzin-Frankel joins Sarah to talk about a burgeoning understanding of the biological roots of anorexia nervosa—an eating disorder that affects about 1% of people in the United States. From genetic links to brain scans, scientists are finding a lot more biology behind what was once thought of as a culturally driven disorder. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).




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Biobased Polyols for Industrial Polymers


 
The replacement of polyols synthesized from petrochemical by polyols originating from natural products, notably from vegetable oils and animal fats, has been the subject of research projects for a number of decades.

Very recently, however, the polymers industry has intensified its efforts to include the “green products”, such as biobased polyols, in applications already available in the market. Examples of such applications include polyurethane foams


Read More...




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Surface and Interface Science, Volumes 7 and 8: Volume 7 - Solid-Liquid and Biological Interfaces; Volume 8 - Applications of Surface


 
In ten volumes, this unique handbook covers all fundamental aspects of surface and interface science and offers a comprehensive overview of this research area for scientists working in the field, as well as an introduction for newcomers.

Volume 1: Concepts and Methods
Volume 2: Properties of Elemental Surfaces
Volume 3: Properties of Composite Surfaces: Alloys, Compounds, Semiconductors
Volume 4: Solid-Solid Interfaces and Thin Films
Volume 5: Solid-Gas

Read More...




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Bio-assay of non-amidated progastrin-derived peptide (G17-Gly) using Tailor-made recombinant antibody fragment and phages display method: A biomedical analysis

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00627K, Paper
Deniz Sadighbayan, Mohammad Reza Tohid-kia, Tayebeh Mehdipour, Mohammad Hasanzadeh, Ahmad Yari Khosroushahi
In this research, four novel and sensitive immunosensor for electrochemical determination of G17-Gly were designed based on signal amplification and tailor-made recombinant antibody technology. Anti-G17-Glyantibody fragments (i.e. scFv and VL...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Determination of total and bioavailable of As and Sb in children’s paints using MSFIA system coupled to HG-AFS

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/C9AY02779C, Paper
Dayara Virginia Lino Ávila, Sidnei OLIVEIRA Souza, Victor Cerdà, Rennan Geovanny Oliveira Araujo
In this work, the application of Doehlert design for the optimisation aiming the determination of As and Sb in gouache and tempera children's paints, using multi-syringe flow injection analysis (MSFIA)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Development of a magnetic dispersive micro-solid-phase extraction method based on a deep eutectic solvent as a carrier for the rapid determination of meloxicam in biological samples

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00095G, Paper
Samira Rastbood, Mohammad Reza Hadjmohammadi, Seyedeh Maedeh Majidi
An environmentally friendly magnetic dispersive micro solid phase extraction based on a deep eutectic solvent as a carrier and disperser of adsorbents.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Elemental chemical composition and As speciation in rice varieties selected for biofortification

Anal. Methods, 2020, 12,2102-2113
DOI: 10.1039/D0AY00294A, Paper
Bruna Moreira Freire, Vivian da Silva Santos, Pericles de Carvalho Ferreira Neves, Juliana Maria Oliveira Souza Reis, Samuel Simião de Souza, Fernando Barbosa, Bruno Lemos Batista
Toxic elements, essential elements and other elements were determined in Brazilian rice by inductively coupled plasma-mass spectrometry (ICP-MS). A method for As speciation using hydride generation was developed and applied in rice samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Development of a paper-immobilized yeast biosensor for the detection of physiological concentrations of doxycycline in technology-limited settings

Anal. Methods, 2020, 12,2123-2132
DOI: 10.1039/D0AY00001A, Paper
Rachel A. Miller, Galen Brown, Elsa Barron, Jamie L. Luther, Marya Lieberman, Holly V. Goodson
To combat pharmaceutical counterfeiting in low- and middle-income countries (LMIC), there is a need for improved low-cost, portable methods that monitor pharmaceutical concentrations relevant to dosage forms and physiological fluids.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Towards simultaneous quantification of protease inhibitors and inflammatory biomarkers in serum for people living with HIV

Anal. Methods, 2020, 12,2196-2196
DOI: 10.1039/D0AY90050H, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Pengyi Wang, Charles S. Venuto, Raymond Cha, Benjamin L. Miller
The content of this RSS Feed (c) The Royal Society of Chemistry




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A rapid and colorimetric biosensor based on GR-5 DNAzyme and self-replicating catalyzed hairpin assembly for lead detection

Anal. Methods, 2020, 12,2215-2220
DOI: 10.1039/D0AY00091D, Paper
Fang Wang, Jianyuan Dai, Hongli Shi, Xiaoqian Luo, Lan Xiao, Cuisong Zhou, Yong Guo, Dan Xiao
A rapid and colorimetric biosensor for Pb2+ detection has been constructed on the basis of Pb2+-dependent GR-5 DNAzyme and the self-replicating catalyzed hairpin assembly (SRCHA) reaction.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hydrothermal synthesis of Auricularia auricula derived nitrogen, phosphorus-doped carbon dots and application in Ag(I) and 4-nitrophenol detection and bioimaging

Anal. Methods, 2020, 12,2237-2243
DOI: 10.1039/D0AY00316F, Paper
Yujiao Tu, Suping Wang, Xiaotian Yuan, Pengfei Song, Yunlin Wei, Kunhao Qin, Qi Zhang, Xiuling Ji
Schematic of the synthetic route for fluorescent Aa N,P-CDs and their application in the detection of 4-NP and Ag(I) and bioimaging.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Selection and optimization of protein and carbohydrate assays for the characterization of marine biofouling

Anal. Methods, 2020, 12,2228-2236
DOI: 10.1039/D0AY00272K, Paper
Chloe Richards, Nicole O'Connor, Diveena Jose, Alan Barrett, Fiona Regan
Biofilms comprise a set of microorganisms attached to a surface through extracellular polymeric substances (EPS). Development of reliable analytical assays are valuable in determining the rate of biofilm attachment on surfaces.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The application of antibody – aptamer hybrid biosensors in the clinical diagnostics and environmental analysis

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00678E, Critical Review
Marta Jarczewska, Elzbieta Malinowska
The growing number of various diseases and the increase of environmental contamination are the causes for elaboration of novel methods for their detection. The possibility of application of affinity-based biosensors...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Classical and Spatial Stochastic Processes [electronic resource] : With Applications to Biology / by Rinaldo B. Schinazi

New York, NY : Springer New York : Imprint: Birkhäuser, 2014




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Statistical Methods and Applications from a Historical Perspective [electronic resource] : Selected Issues / edited by Fabio Crescenzi, Stefania Mignani

Cham : Springer International Publishing : Imprint: Springer, 2014




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Interventional ultrasound of the breast: from biopsy to ablation / Bruno D. Fornage

Online Resource




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The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology Andrew S. Field, Wendy A. Raymond, Fernando Schmitt, editors

Online Resource




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Life-Cycle Design, Assessment, and Maintenance of Structures and Infrastructure Systems edited by Fabio Biondini, et al

Online Resource




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Ibn Khaldun : an intellectual biography / Robert Irwin

Irwin, Robert, 1946- author




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[ASAP] “Sample-to-Answer” Detection of Rare ctDNA Mutation from 2 mL Plasma with a Fully Integrated DNA Extraction and Digital Droplet PCR Microdevice for Liquid Biopsy

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00818




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[ASAP] In Situ Incorporation of Fluorophores in Zeolitic Imidazolate Framework-8 (ZIF-8) for Ratio-Dependent Detecting a Biomarker of Anthrax Spores

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00499




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[ASAP] Bifunctional Au@Pt/Au core@shell Nanoparticles As Novel Electrocatalytic Tags in Immunosensing: Application for Alzheimer’s Disease Biomarker Detection

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00760




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[ASAP] Discovering New Lipidomic Features Using Cell Type Specific Fluorophore Expression to Provide Spatial and Biological Specificity in a Multimodal Workflow with MALDI Imaging Mass Spectrometry

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00446




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[ASAP] Metal Ion-Mediated Potential-Resolved Ratiometric Electrochemiluminescence Bioassay for Efficient Determination of miR-133a in Early Diagnosis of Acute Myocardial Infarction

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00377




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[ASAP] Tag-Free Methodology for Ultrasensitive Biosensing of miRNA Based on Intrinsic Isotope Detection

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c01295




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Microbes and Enzymes in Soil Health and Bioremediation Ashok Kumar, Swati Sharma, editors

Online Resource




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Medically important plant biomes: source of secondary metabolites / Dilfuza Egamberdieva, Antonio Tiezzi, editors

Online Resource




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Powdery mildew disease of crucifers: biology, ecology and disease management / Govin Singh Saharan, Naresh K. Mehta, Prabhu Dayal Meena

Online Resource




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In Vitro Plant Breeding Towards Novel Agronomic Traits: Biotic and Abiotic Stress Tolerance / Manoj Kumar, Annamalai Muthusamy, Vivek Kumar, Neera Bhalla-Sarin, editors

Online Resource