A connector for a fluid path set for delivery of a fluid to a patient during a procedure is described. The connector includes a magnetic check valve for limiting fluid flow to one direction through the fluid path. The magnetic check valve is configured to open in response to one or more of fluid pressure and change in value of magnetic force in the check valve.

Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.

A wheel speed sensor for a motor vehicle can be supplied with an operating voltage by a control device. The control device has a load resistance with a load resistance value. An operating voltage can be at a voltage input by the control device. An electrical circuit is designed to determine a turn-on or a turn-off voltage value according to the load resistance value. An operation control is designed to transfer the wheel speed sensor into a normal operation using the operating voltage, when the turn-on voltage value is exceeded, and to transfer the wheel speed sensor into an emergency operation using the operating voltage, when a turn-off voltage value is not met. In emergency operation only a low constant signal level is emitted.

A force-biased spring probe pin assembly includes a barrel member having a barrel wall defining an elongate internal cavity with a lower end and an upper end. The assembly also includes a first plunger member reciprocally mounted in the internal cavity proximate the lower end of the internal cavity. A spring member is positioned in the internal cavity between the plunger member and the second end of the internal cavity. At least one rectangular cavity formed in the plunger member with a movable cylindrical bearing in the cavity that applies a slight transverse force to the plunger member ensuring good electrical contact between the plunger and the wall of the barrel member. A force-biased spring probe pin assembly includes a barrel member having a barrel wall defining an elongate internal cavity with a lower end and an upper end. The assembly also includes a first plunger member reciprocally mounted in the internal cavity proximate the lower end of the internal cavity and a second plunger member reciprocally mounted in the internal cavity proximate the upper end of the internal cavity. A spring member is positioned in the internal cavity between the first plunger member and the second plunger member. At least one rectangular cavity formed in the first plunger member with a first movable cylindrical bearing in the cavity that applies a slight transverse force to the first plunger member ensuring good electrical contact between the first plunger member and the wall of the barrel member and at least one rectangular cavity formed in the second plunger member with a second movable cylindrical bearing in the cavity that applies a slight transverse force to the second plunger member ensuring good electrical contact between the second plunger member and the wall of the barrel member

A force biased spring probe pin assembly includes a barrel member having a barrel wall defining an elongate internal cavity with a lower end and an upper end. The assembly also includes a split plunger member comprised of an upper split plunger part separated from a lower split plunger part separated by a diagonal cut reciprocally mounted in the internal cavity proximate the lower end of the internal cavity. A spring member is positioned in the internal cavity between the upper split plunger part and the second end of the internal cavity. A force biased spring probe pin assembly includes a barrel member having a barrel wall defining an elongate internal cavity with a lower end and an upper end. The assembly also includes a first split plunger member reciprocally mounted in the internal cavity proximate the lower end of the internal cavity and a second split plunger member reciprocally mounted in the internal cavity proximate the upper end of the internal cavity. The first and second split plunger members are each comprised of two parts: a first upper plunger part separated from a first lower plunger part by a diagonal cut. A spring member is positioned in the internal cavity between the first and second upper split plunger parts. In each split plunger the diagonal surface of the upper split plunger part exerts a transverse force to the diagonal surface of the lower split plunger part ensuring good electrical contact between the lower split plunger member part and the barrel wall.

A sensored electrical jumper comprises a conductor having a first end and a second end, the first end including a first connection interface and the second end including a second connection interface, a sensor section including at least one sensor disposed over the conductor between the first and second ends, the sensor section sensing at least one of current and voltage of the conductor, and a sensor output conduit extending from the sensor and oriented substantially perpendicular to the conductor axis to protect at least one sensor output wire from leakage current or other potential electrical damage.

An electronic arrangement and method for providing a signal characterized by reduced phase noise having a signal source for providing a stimulus signal, a modulator coupled to the signal source for generating a modulated signal as function of the stimulus signal and a local oscillator signal, and a mixer combining the stimulus and modulated signals to generate a mixed signal that includes a component characterized by a mathematical difference of the stimulus signal and the modulated signal. The modulated signal is substantially identical to the stimulus signal and offset by a frequency of the local oscillator signal, so that the difference component of the mixed signal results in a local oscillator signal wherein the stimulus signal phase noise generated by the signal source has been mathematically cancelled.

A method for preparing an object to be tested, having a given relative permittivity, intended to be illuminated by an incident electromagnetic wave. The method includes: providing a part including a cavity for housing the object and at least one extension element made from a material having a relative permittivity that is preferably equal to that of the object, the extension element at least partially delimiting the cavity and extending to either side of the cavity in a passage direction of the cavity, over a length at least equal, on either side of the cavity, to one third of the length of the cavity in the passage direction, and placing the object in the cavity, such that the object is in contact with the extension element in the passage direction.

The invention relates to a high-voltage dry apparatus having a semiconductor layer (2) covered by a metal screen (3), this screen (3) being eliminated so as to expose this semiconductor layer (2) over a length, this cable being connected to an element of equipment having an outer envelope (6) mechanically connected to said screen. According to the invention, an electronic monitoring arrangement (20) is contained within said envelope (6), this electronic arrangement (20) being electrically connected to an electrical power supply arrangement (21) surrounding said semiconductor layer (2) and to the metal screen (3) of said cable on either side of said length of the exposed semiconductor layer.

A universal, modular, temperature controlled MRI phantom for calibration and validation for anisotropic and isotropic imaging comprises an outer insulating shell configured to be received within an MRI chamber; an inner shell received within the outer insulating shell; a fluid conduits adjacent the inner shell for receiving temperature controlling fluid or gas cycling there-through; and a series of stacked layers of frames containing test points for the MRI phantom, each layer including at least one fiducial and including at least some anisotropic imaging test points in at least one frame and at least one isotropic imaging test point in at least one frame. The anisotropic imaging comprises hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 50 microns and an inner diameter of less than 20 microns, wherein at least some hollow tubular fibers are filled with a fluid.

Acquiring seismic data using time-distributed sources and converting the acquired data into impulsive data using a multiple-frequency approach. The methods are performed in frequency-source location domain, frequency-wavenumber domain, or frequency-slowness domain. The methods are applicable to single source acquisition or simultaneous source acquisition.

Disclosed is a device for detecting wall abrasion of a solid-filling feeding well and a detection method thereof. The device comprises a well wall abrasion detector, a horizontal displacement meter, a vertical displacement monitor, and a limit guide rod. One end of the limit guide rod is connected to the well wall abrasion detector. The signal output terminal of the well wall abrasion detector is connected to the signal input terminal of the horizontal displacement meter, and the other end of the limit guide rod passes through the vertical displacement monitor for slidable setting. This disclosure mainly utilizes a resistance strain displacement sensor to detect the abrasion and deformation degree of the well wall, determines the position of damages with the vertical displacement monitor, and draws wall abrasion curves by using the obtained data. The device provided is easy to use, has low cost, has high reliability, and can effectively detect the wall abrasion condition of a solid-filling feeding well, thereby providing a basis for ensuring the working efficiency of the feeding well.

A flow speed measurement method includes conducting a heat exchange at a prescribed part of a surface of a pipe, the flow speed measurement method further includes measuring a temperature distribution in a pipe-axis-direction on the surface of the pipe in a case that the heat exchange has been conducted at the prescribed part, and the flow speed measurement method further includes determining a flow speed of a thermal fluid flowing inside the pipe, based on the temperature distribution measured.

Pre-loaded force sensitive input devices, force sensing resistors (FSR), are formed as a multiple membrane assembly that is capable of detecting low intensity pressure inputs and quantifying varying applications of pressure to the sensor surface. Pre-loading the force sensor elements results in controlled amount of force between the two substrates causing a constant state of pre-load and eliminating the low-end or minimal pressure signal noise associated with unloaded sensors. Pre-loading the force sensing resistor sensors also enables the sensor to detect removal of low intensity pressure input such as might occur during theft of light weight articles placed in contact with the pre-loaded force sensor. Using an FSR or FSR Matrix Array will enable any handling of protected retail packaging to be detected and identified. A library of “touches” can be established that will yield cutting, ripping, twisting, etc. making the detection of a theft in progress more accurate.

A planet gear train based torque detector is provided with idler gears between an input shaft and an output shaft wherein a rotation of the input shaft rotates the idler gears which rotate the output shaft, and a force is applied to a tangent line between each idler gear and the input shaft; peripheral resilient members, each having a fixed first end and a second end for receiving force applied thereon by the revolution of idler gears; and at least one strain gauge, each attached on one resilient member for measuring a deformation at the resilient member due to the revolution of the idler gears. A torque between the input shaft and the output shaft is obtained by calculating the deformation. The resilient members parallel the input shaft.

A sensor for detecting a pressure of a fluid medium is provided. The sensor includes a sensor element for detecting the pressure of the fluid medium, a supply duct for supplying the fluid medium to the sensor element and a control and/or evaluation circuit for processing signals of the sensor element. The control and/or evaluation circuit is situated on the sensor element.

A percolation network of functionalised reduced graphene oxide flakes, the percolation network configured to allow for hopping of charge carriers between adjacent reduced graphene oxide flakes to enable a flow of charge carriers through the percolation network, and wherein the reduced graphene oxide flakes are functionalised to facilitate detectable changes in the flow of charge carriers in response to a stimulus to the percolation network.

A flexible, foldable light-weight gas chromatography transfer line suitable for connecting a gas chromatograph (GC) to a spectrometer, such as a mass spectrometer or optical spectrometer, in particular to the ion source of the spectrometer, such as an inductively coupled plasma (ICP) ion source. The transfer line has a heating arrangement that allows maintaining an even temperature profile, which improves quality of spectra. The transfer line has low thermal mass and the heating can be controlled with the control unit of the GC.

A vacuum-assisted in-needle capillary adsorption trap (VA-INCAT) device for sampling and delivering materials to an analytical device is disclosed. A sorbent is multiwall carbon nanotube/polyaniline (PANI/MWCNT) nanocomposite and is coated within an interior space of the needle between the second end and the side aperture to entrap an analyte within a sample. The VA-INCAT device also includes a vacuum device configured to vacuum the vacuum flask to improve the extraction of the analytes vapors from the sample matrix to the sorbent bed.

An electronic circuit for amplifying signals with two components in phase quadrature, which includes: a feedback amplifier with a feedback capacitor; a switch that drives charging and discharging of the feedback capacitor; an additional capacitor; and a coupling circuit, which alternatively connects the additional capacitor in parallel to the feedback capacitor or else decouples the additional capacitor from the feedback capacitor. The switch opens at a first instant, where a first one of the two components assumes a first zero value; the coupling circuit decouples the additional capacitor from the feedback capacitor in a way synchronous with a second instant, where the first component assumes a second zero value.

The invention provides a method for acquiring fragment ion spectra of substances in complex substance mixtures wherein a trapped ion mobility spectrometer (“TIMS”) is used as the ion mobility separation device coupled to a triple quadrupole mass filter assembly. The fragment ion spectra may be used for the identification of high numbers of proteins in complex mixtures, or for a safe quantification of some substances, by their fragment ion mass spectra in a mass spectrometer with upstream substance separator. TIMS, in particular equipped with parallel accumulation, provides the unique possibility to prolong the ion accumulation duration to find more detectable ion species without decreasing the measuring capacity for fragment ion mass spectra. The high measurement capacity for fragment ion mass spectra permits the repeated measurement of low abundance ion species such as to improve the quality of the fragment ion spectra.

A process for fabricating an organic photodetector is presented. The process includes providing an array of thin film transistor assemblies, each thin film transistor assembly including a first electrode disposed on a thin film transistor; disposing an organic semiconductor layer on the array; disposing a second electrode layer including a first inorganic material on the organic semiconductor layer through a shadow mask to form a first etch stop layer; and removing portions of the organic semiconductor layer unprotected by the first etch stop layer using a dry etching process to form a multilayered structure. An organic photodetector, for example an organic x-ray detector fabricated by the process is further presented. An x-ray system including the organic x-ray detector is also presented.

A method and apparatus for controlling a dose of extreme ultraviolet (EUV) radiation generated by a laser produced plasma (LPP) EUV light source. In one embodiment, a running total of the EUV energy generated over a predetermined number of laser pulses is measured; once that number of pulses is exceeded, the energy from the pulse immediately preceding the most recent predetermined number of pulses is dropped from the running total, so that the running total is from the most recent predetermined number of pulses. If the running total of the EUV energy exceeds a target dose, the next pulse is caused to not hit a droplet. This avoids the unwanted side effects of various prior art solutions, such as needing to miss many droplets in a row, or requiring the laser pulses to be shortened or reduced in power as in other prior art solutions.

The invention relates to a method for controlling the divergence of a jet of particles in vacuo with an aerodynamic lens, the aerodynamic lens including at least one chamber; a diaphragm, a so-called inlet diaphragm, intended to form an inlet of the aerodynamic lens for a jet of particles, the inlet diaphragm having a given diameter (d1); and another diaphragm, a so-called outlet diaphragm, intended to form an outlet of the aerodynamic lens for this jet of particles; the method including: a step for generating the jet of particles from the inlet to the outlet, in vacuo, of the aerodynamic lens; and a step for adjusting the diameter (ds) of the outlet diaphragm for controlling the divergence of the jet of particles.

The application provides a printed circuit board and an optical module so as to alleviate poor contact between the electro-conductive contact sheet group and the clamping piece due to the solder resist. The printed circuit board includes a substrate, and electro-conductive wirings and electro-conductive contact sheet group both laid on the surface of the substrate, where the substrate is overlaid with solder resist, and the solder resist has no contact with the electro-conductive contact sheet group.

Disclosed is an apparatus configured for collection and sterilization of expectorates. According to the embodiments of the invention, the apparatus includes a receptacle having an interior space defined by a bottom wall, and one or more side walls, an opening at a top portion for selectively receiving a separator for the expectorates to pass therethrough and be received at the interior space, and a power source, one or more light sources, such as ultraviolet (UV) light source radiating rays of sufficient wavelengths capable of sterilizing the expectorates received at the interior space, a reflective source surrounding the interior space of the receptacle for substantially reflecting the radiated rays throughout the interior space to effectively sterilize the expectorates received at the interior space, and a receptacle lid removably engaging the separator to close the opening at the top portion of the receptacle.

The present technology provides methods for increasing sensitivity of detection and/or quantification of a negatively charged analyte, e.g., an oligonucleotide, using an analytical system that comprises liquid chromatography and mass spectrometry. The methods comprise passing an acidic solution through the analytical system, i.e., through a fluidic path from the mobile phase reservoir to the detector to remove or displace, at least in part, metal ions adsorbed to charged sites in the fluidic path.

An electronic device may have a display with a cover layer. A light-based component such as an infrared-light proximity sensor or other infrared-light-based component may be aligned with a window in the display cover layer. The window may block visible light and transmit infrared light. A coating in the window may include a thin-film filter formed from a stack of inorganic dielectric layers. The thin-film filter may block visible light and transmit infrared light. The coating may also include at least one layer of material such as a semiconductor material that absorbs visible light and that passes infrared light. This material may be interposed between the thin-film filter and the display cover layer. Antireflection properties and color adjustment properties may be provided using thin-film layers between the thin-film filter and the display cover layer.

The present disclosure provides one embodiment of an IC method. First pattern densities (PDs) of a plurality of templates of an IC design layout are received. Then a high PD outlier template and a low PD outlier template from the plurality of templates are identified. The high PD outlier template is split into multiple subsets of template and each subset of template carries a portion of PD of the high PD outlier template. A PD uniformity (PDU) optimization is performed to the low PD outlier template and multiple individual exposure processes are applied by using respective subset of templates.

Superconducting nanowire avalanche photodetectors (SNAPs) have using meandering nanowires to detect incident photons. When a superconducting nanowire absorbs a photon, it switches from a superconducting state to a resistive state, producing a change in voltage that can be measured across the nanowire. A SNAP may include multiple nanowires in order to increase the fill factor of the SNAP's active area and the SNAP's detection efficiency. But using multiple meandering nanowires to achieve high fill-factor in SNAPs can lead to current crowding at bends in the nanowires. This current crowding degrades SNAP performance by decreasing the switching current, which the current at which the nanowire transitions from a superconducting state to a resistive state. Fortunately, staggering the bends in the nanowires reduces current crowding, increasing the nanowire switching current, which in turn increases the SNAP dynamic range.

In an example arrangement an apparatus includes a semiconductor substrate having a front side surface including circuitry and a backside surface opposing the front side surface; a plurality of metal conductors formed over a front side surface of the semiconductor substrate; at least one cavity opening etched in a backside surface of the semiconductor substrate; and a radiator formed in a portion of the metal conductors and configured to radiate signals through the cavity opening in the backside surface. Methods and additional apparatus arrangements are also disclosed.

A fuel additive imparting high lubricity to gasoline and diesel fuels while concurrently increasing miles and reducing emissions. The fuel additive is formed of a plurality of individual components having individual and a combined synergistic effect along with components increasing fuel lubricity which are mixed with a liquid fuel-soluble carrier and added to the fuel supply of internal combustion engines.

A method that includes clarifying a thin stillage product in a mechanical processor to produce a fine suspended solids stream and a clarified thin stillage is provided. The method further includes providing the thin stillage product and the clarified thin stillage, separately or in a combined stream, to one or more evaporators to produce one or more reduced suspended solids streams, each stream having a reduced amount of suspended solids and a lower viscosity as compared to process streams having a comparable total solids content but containing a higher amount of suspended solids. The method can further included further processing of one or more of the reduced suspended solids streams to produce a bio-oil product.

A fuel additive and its preparation for a engine, a fuel containing the additive, a fuel additive concentrate, a method for improving performance of fuel injectors and a method for cleaning fuel injectors for an engine. The fuel additive includes a quaternary ammonium salt derived from a reaction of a hydrocarbyl substituted anhydride, a tertiary amine and a hydroxyl-containing epoxide, wherein the tertiary amine is devoid of primary and secondary amino groups.

A method for obtaining diesel fuel from vegetable or animal oils through the addition of hydrogen in the presence of catalysts under suitable temperature and pressure conditions is described. The method is different from other similar methods in that it involves the use of space velocities of between 5.1 h-1 and 9 h-1, thereby enabling a reduction in the size of the reactor and in hydrogen consumption, as well as lowering construction and operating costs. The invention also relates to the products obtained using said method, which have demonstrated that in additions, even below 10%, they improve the performance of diesel engines, thereby lowering fuel consumption.

A method for controlling the manufacture and certification of an oxygenated gasoline product is carried out by manufacturing a gasoline Basestock for Oxygenate Blending (BOB) at a refinery site in accordance with an empirical relationship, valid for at that site under typical manufacturing conditions, between (i) a property value of the BOB stream such as octane as determined by an on-site online process analyzer and (ii) the corresponding instantaneous value or FPAPV property value as determined by the test method mandated by the product specification for the final gasoline stream when blended with the required proportion of oxygenate. The quality of fit of this empirical relationship is calculated according to the standard deviation of the residuals of the relationship and a confidence level is fixed so that the final oxygenated gasoline formulated with the BOB will meet the required property specification when measured by the test method mandated by the specification. The final oxygenated gasoline blend is certified as having a property value conforming to the required specification based on the predicted property value for the finished gasoline.

Methods for producing alcohols and oligomers contemporaneously from a hydrocarbon feed containing mixed butenes using an acid based catalyst are provided. Additionally, methods for producing fuel compositions having alcohols and oligomers prepared from mixed olefins are also provided as embodiments of the present invention. In certain embodiments, the catalyst can include a dual phase catalyst system that includes a water soluble acid catalyst and a solid acid catalyst.

Systems and methods for producing engineered fuels from municipal solid waste material are described herein. In some embodiments, a method includes combining a first waste stream that includes at least one of hard plastic, soft plastic and mixed plastic with a sorbent and increasing the temperature of the combined first waste stream and sorbent to a temperature of at least about 200° C. The method further includes combining the thermally treated first waste stream and sorbent with a second waste stream that includes fiber, and compressing the combined first waste stream, sorbent, and second waste stream to form a densified engineered fuel feedstock.

Modified solid fuel manufacturing method and modified solid fuels manufactured using the manufacturing method. When solid fuels are manufactured by crushing low grade coal, mixing the crushed low grade coal with solvent oil to prepare a slurry, heating the slurry to at least the boiling point of water to evaporate moisture included in the slurry, separating the solvent oil from the slurry to produce charcoal dust and compression compacting said charcoal dust, by heating the slurry to at least the boiling point of water, the non-volatile components included in the low grade coal are extracted with the solvent oil, the outer surface of the low grade coal and the internal surfaces of the pores are coated with the extracted non-volatile components, and the content of heavy oil added from the outside will be less than 0.5 mass % relative to the solid fuel after drying.

The present disclosure is directed to a middle distillate fuel composition comprising a friction modifying effective amount of a hydrocarbyl-substituted succinimide derived from maleic anhydride, polyisobutylene and ammonia; and a middle distillate fuel. A method for modifying friction in a compression engine comprising providing to the engine the disclosed fuel composition is also disclosed. Moreover, there is disclosed a method for improving fuel mileage.

Present embodiments include systems for reducing moisture in a solid feed provided to a gasifier. For example, in an embodiment, a feedstock preparation system includes an aspirator having a first inlet for receiving a flow of steam, a second inlet for receiving a flow of a moist gaseous phase from a grinding mechanism configured to grind a solid fuel in the presence of a conveyance gas. The moist gaseous phase includes the conveyance gas and moisture removed from the ground solid fuel. The aspirator also includes an outlet configured to output a reduced pressure flow having the steam and the moist gaseous phase. The aspirator is configured to enhance moisture removal from the ground solid fuel to produce a dry feed of the ground solid fuel. The aspirator discharge is recycled within the process to heat the incoming dry conveyance gas and improve system efficiency.

A compound having formula (Ph3C)mAr(OR)n, wherein Ph represents a phenyl group, Ar is an aromatic ring system having from six to twenty carbon atoms, R is C1-C18 alkyl or C7-C12 aralkyl, m is one or two, and n is an integer from one to four.

A method for improving performance of fuel injectors, and a method for cleaning fuel injectors for an internal combustion engine. The methods include operating the engine on a fuel composition comprising a major amount of fuel and from about 1 to about 200 ppm by weight based on a total weight of the fuel of a reaction product of (i) a hydrocarbyl substituted compound containing at least one tertiary amino group and (ii) a halogen substituted C2-C8 carboxylic acid, ester, amide, or salt thereof, wherein the reaction product as made is substantially devoid of free anion species.

The present invention relates generally to processes for preparing agglomerated particulate low-rank coal feedstocks of a particle size suitable for reaction in a fluidized-bed reactor and certain other gasification reactors and, in particular, for coal gasification and combustion applications. The present invention also relates to integrated coal gasification and combustion processes including preparing and utilizing such agglomerated particulate low-rank coal feedstocks.

A process is provided comprising subjecting a quantity of plant biomass fibers to a pretreatment to cause at least a portion of lignin contained within each fiber to move to an outer surface of said fiber, wherein a quantity of pretreated tacky plant biomass fibers is produced; and densifying the quantity of pretreated tacky plant biomass fibers to produce one or more densified biomass particulates, wherein said biomass fibers are densified without using added binder.

A method for removing glyphosate from a solution by contacting the solution with a polymeric particle including a moiety selected from the group consisting of ammonium, amine and combinations thereof, wherein the moiety is positively charged in the solution.

Provided is a method for reducing COD of wastewater with improved utilization efficiency of ozone. The method achieves an objective by adding agents for removing hydroxyl radical scavengers produced by base-catalyzed ozone advanced oxidation to wastewater. The addition of calcium ion, barium ion, etc. to a base-catalyzed ozonation system makes the hydroxyl radical scavengers form precipitates, separated from water and lose the capability of scavenging hydroxyl radicals, thereby enhancing ozone utilization efficiency. Furthermore, calcium ion, barium ion, etc. form precipitates with partial organic acids yielded in the wastewater ozonation and are separated from water, hence diminishing ozone consumption and indirectly improving the ozone utilization efficiency in the wastewater treatment. The present invention can not only significantly enhance the reaction rate and utilization efficiency of ozone, saving reaction time and costs, but also enable complete mineralization of the organic compounds, significantly reducing COD and total phosphorus of wastewater.

A preparation method of Bacillus subtilis biological composite material loaded with Fe3O4 magnetic nanoparticles with core-shell structure includes the following steps: 1) preparation of Fe3O4 nanoparticles, 2) preparation of Fe3O4@mSiO2 nanoparticles, 3) preparation of Fe3O4@mSiO2@MANHE nanoparticles; and 4) preparation of Bacillus subtilis@Fe3O4@mSiO2@MANHE composite.

The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction.

A method of manufacturing a refined pitch includes the steps of providing a pitch and performing a heated blending process thereon to produce a pitch solution; adding an aromatic additive to the pitch solution; adding an aliphatic additive to the pitch solution; performing a quiescent sedimentation process on the pitch solution; and separating a liquid part from the pitch solution. Therefore, the method allows a concentrated mesophase pitch to be manufactured quickly and by heat processing.