The owner of a Detroit-area physical therapy clinic was sentenced to 11 years in prison today for his role in a drug diversion scheme.

ENTERCOM AC WDZH (98.7 THE BREEZE)/DETROIT Middayer KIM ADAMS has teamed up with D.A. ALEXANDER AND COMPANY to surprise, honor and show appreciation to nurses in celebration of National … more

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The 2012 french president's election from the side of political activists.

CEDAR RAPIDS — A Dubuque woman who helped her boyfriend and another person buy heroin that later led to a fatal overdose was convicted Thursday in federal court. Jacqueline M. Birch, 23,...

CEDAR RAPIDS — A Dubuque woman who helped her boyfriend and another person buy heroin that later led to a fatal overdose was convicted Thursday in federal court.

Jacqueline M. Birch, 23, pleaded guilty in U.S. District Court to one count of aiding and abetting the distribution of a controlled substance.

During the plea hearing, Birch admitted she knew that another person was going to illegally distribute a drug last May, and she aided in that distribution.

Evidence at a previous hearing showed that Birch drove her boyfriend, Mateusz Syryjczyk, 29, of Rockford, Ill., and another person, not identified in court documents, to a residence in Dubuque on May 27. Birch and the other person went into the residence and bought heroin from a dealer. The three drove to a hotel in Dubuque and all used the heroin.

The other person began to overdose in the room, but Birch and Syryjczyk didn’t immediately call 911, according to evidence. Over many hours, Birch occasionally would perform CPR on the person to restore some breathing function, though the person never regained consciousness.

Eventually, Birch and Syryjczyk decided to call 911, and Syryjczyk took the remaining drug paraphernalia from the room to prevent law enforcement from finding it, according to court documents. Birch and Syryjczyk also made false statements to police about the cause of the person’s condition.

Court documents showed the overdose victim died at the scene. An autopsy later determined the cause of death was use of heroin, fentanyl and valeryl fentanyl.

Syryjczyk previously pleaded to misprision of a felony and remains free on bond pending sentencing.

Birch faces up to 20 years in federal prison, a $1 million fine and supervised release for life following her prison term.

Sentencing will be set after a presentencing report is prepared.

The case was investigated by the Dubuque Drug Task Force and is being prosecuted by Assistant U.S. Attorney Dan Chatham.

Comments: (319) 398-8318; trish.mehaffey@thegazette.com

https://thenextweb.com/microsoft/2020/05/08/microsoft-bundled-its-beautiful-bing-wallpapers-into-a-free-android-app/

In today’s Adobe Illustrator tutorial I’m going to take you through the process of creating a colourful embroidered patch, based on the kinds of designs associated with National Parks. The artwork will incorporate a landscape scene at sunset, which helps to keep the design simple with a silhouette graphic and a warm colour palette. Stick […]

The post Video Tutorial: How to Create an Embroidered Patch Design in Illustrator appeared first on Spoon Graphics.

We introduce the conormal fan of a matroid M, which is a Lagrangian analog of the Bergman fan of M. We use the conormal fan to give a Lagrangian interpretation of the Chern-Schwartz-MacPherson cycle of M. This allows us to express the h-vector of the broken circuit complex of M in terms of the intersection theory of the conormal fan of M. We also develop general tools for tropical Hodge theory to prove that the conormal fan satisfies Poincar'e duality, the hard Lefschetz theorem, and the Hodge-Riemann relations. The Lagrangian interpretation of the Chern-Schwartz-MacPherson cycle of M, when combined with the Hodge-Riemann relations for the conormal fan of M, implies Brylawski's and Dawson's conjectures that the h-vectors of the broken circuit complex and the independence complex of M are log-concave sequences.

The Gabriel-Roiter measure is used to give an alternative proof of the finiteness of the representation dimension for Artin algebras, a result established by Iyama in 2002. The concept of Gabriel-Roiter measure can be extended to abelian length categories and every such category has multiple Gabriel-Roiter measures. Using this notion, we prove the following broader statement: given any object $X$ and any Gabriel-Roiter measure $mu$ in an abelian length category $mathcal{A}$, there exists an object $X'$ which depends on $X$ and $mu$, such that $Gamma = operatorname{End}_{mathcal{A}}(X oplus X')$ has finite global dimension. Analogously to Iyama's original results, our construction yields quasihereditary rings and fits into the theory of rejective chains.

A perfect matroid design (PMD) is a matroid whose flats of the same rank all have the same size. In this paper we introduce the q-analogue of a PMD and its properties. In order to do that, we first establish new cryptomorphic definitions for q-matroids. We show that q-Steiner systems are examples of q-PMD's and we use this matroid structure to construct subspace designs from q-Steiner systems. We apply this construction to S(2, 13, 3; q) Steiner systems and hence establish the existence of subspace designs with previously unknown parameters.

The disclosed embodiments describe a method, an apparatus, an application specific integrated circuit, and a server that provides a fast and efficient look up for data analysis. The apparatus and server may be configured to obtain data segments from a plurality of input devices. The data segments may be individual unique subsets of the entire data set obtained by a plurality input devices. A hash function may be applied to an aggregated set of the data segments. A result of the hash function may be stored in a data structure. A codebook may be generated from the hash function results.

A microprocessor capable of running both x86 instruction set architecture (ISA) machine language programs and Advanced RISC Machines (ARM) ISA machine language programs. The microprocessor includes a mode indicator that indicates whether the microprocessor is currently fetching instructions of an x86 ISA or ARM ISA machine language program. The microprocessor also includes a plurality of model-specific registers (MSRs) that control aspects of the operation of the microprocessor. When the mode indicator indicates the microprocessor is currently fetching x86 ISA machine language program instructions, each of the plurality of MSRs is accessible via an x86 ISA RDMSR/WRMSR instruction that specifies an address of the MSR. When the mode indicator indicates the microprocessor is currently fetching ARM ISA machine language program instructions, each of the plurality of MSRs is accessible via an ARM ISA MRRC/MCRR instruction that specifies the address of the MSR.

A method for operating an invisible system service on Android platform is disclosed. The method for operating system services on Android platform includes selectively registering a created system service in a context manager according to a type of the created system service, where the type of the system service comprises a first type for permitting access from an outside and a second type for not permitting access from the outside, and the selectively registering comprises registering in the context manager the created system service belonging to the first type and not registering in the context manager the created system service belonging to the second type.

A device for electroimpedance tomography with an electrode belt (2), which has electrodes (E1 . . . E16), wherein at least two groups (5, 6) of electrodes located next to each other are formed and the electrodes of one group are contacted with at least one, multiwire feed cable (7, 8). For a reduced noise level during data acquisition, provisions are made for at least one electrode (E9) of two mutually adjacently located electrodes (E8, E9) of two different groups (5, 6) to have an additional electrode feed line (15), which is led over the feed cable (7) of the adjacent group (5).

Steroid compounds having increased resistance against metabolism and increased water solubility are disclosed, together with methods for their production. These substances are suitable for the manufacture of pharmaceuticals for the treatment of steroid related or steroid induced CNS disorders and for use in methods of prevention, alleviation or treatment of such disorders.

The present invention relates to a process for the preparation of 17α-(3-hydroxypropyl)-17β-hydroxysteroids of the formula I starting from 17-ketosteroids of the formula III via the intermediates of the formula V wherein the radicals R3, R5, R6, R7, R10, R13, R15, R16, R40, R41 and R42 have the meaning indicated in the description.

The invention relates to nitrooxyderivative of corticosteroids of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof R—(Z)a—Rx (I) wherein R is the corticosteroid residue of formula (II): wherein: R1 is OH, R2—CH3, or R1 and R2 are taken together to form a group of formula (III) R3 is Cl or F;R4 is H or F; wherein R1, R2, R3 and R4 can be linked to the correspondent carbon atoms of the steroidal structure in position α or β; with the proviso that: when R1 and R2 are the group of formula (III) then R3 is F and R4 is H or F; The compounds are useful in the treatment of respiratory diseases, inflammatory diseases, dermatological diseases and ocular diseases.

The invention relates to compounds of formula (I): wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.

The invention relates to a process for the preparation of a compound of formula (I): wherein R1 and R2 are as defined in the description, by reaction of a compound of formula (II) with a base. Compound (I) is an intermediate useful in the preparation of gestodene.

Devices and methods for gastrointestinal bypass are described. A gastrointestinal bypass device includes a gastrointestinal cuff and a gastrointestinal sleeve. The cuff may be configured to be attached in the esophagus, and may be sufficiently flexible to expand and collapse to conform with the inside of the esophagus to allow the esophagus to function substantially normally. The sleeve is configured to be coupled to the cuff, and may be made of a material that is floppy or flaccid but does not substantially expand radially.

A method for treating spheroidal graphite iron includes the step: pouring molten spheroidal graphite iron into a pouring electrical furnace (1); covering the molten spheroidal graphite iron (5) with alkali slag (6) which is melted at high temperature and rich in alkali earth metal ion, rare earth metal ion, or mixture of them; connecting the molten spheroidal graphite iron (5) with the negative pole of the direct current source by one pole (7); connecting the alkali slag (6) with the positive pole of the direct current source by another pole (4), treating the molten spheroidal graphite iron (5) with the alkali slag (6) which is used as electrolyte. The method can prevent the spheroidized fading velocity of the spheroidal graphite iron. The pouring electrical furnace can be used for treating the molten spheroidal graphite iron.

A light absorption anisotropic film, having at least one dichroic dye, in which the light absorption anisotropic film shows a diffraction peak derived from a periodic structure in a direction in a plane of the light absorption anisotropic film in X-ray diffraction measurement and the diffraction peak has a half width of 1.0 Å or less.

A hypoxia contrast medium including nitroimidazole-amino acid chelate with a positively charged radioactive nuclide, a preparation method and use thereof. The contrast medium can be used in imaging cerebral thrombosis, tumors or other diseases such as ulceration, thrombosis, and so on.

Described is a black dichroic dye composition comprising 2 or more dyes, wherein at least one dye, generally a red dye and optionally a yellow dye, conforms to the formula A and at least one dye, usually a blue dye, conforms to the formula B Ar1—N═N—[Ar2—N═N—]qAr3—N═N—Ar4 (B) with symbols as defined in present claims. The dye composition is well suited for combination with liquid crystal material for use, inter alia, as polarizing film and/or in liquid crystal displays, showing, inter alia, high dichroic ratio and excellent compatibility with the LC material.

An apparatus and method are disclosed for controlling fluid flow to a variator which responsive to separate high and low pressure fluids to control an output torque thereof. A first trim valve may be responsive to a first control signal to supply a first fluid at a fluid outlet thereof. A second trim valve may be responsive to a second control signal to supply a second fluid at a fluid outlet thereof. A variator switching sub-system may controllably supply the high pressure fluid and the low pressure fluid to the variator. A multiplex valve may be fluidly coupled to the outlets of the first and second trim valves, and may supply the first fluid as the high pressure fluid to the variator switching sub-system during at least one predefined operating condition and may otherwise supply the second fluid as the high pressure fluid to the variator switching sub-system.

A toroidal continuously variable transmission includes: an input disk; an output disk; a plurality of power rollers; a plurality of trunnions; an oil pump; a pressing hydraulic mechanism that moves and brings the input disk and output disk closer to each other; a shifting hydraulic mechanism that moves the trunnions forward and rearward; and a hydraulic control device that controls the pressing hydraulic mechanism and the shifting hydraulic mechanism by oil pressure. The hydraulic control device has an oil pressure regulation unit that sets an oil pressure in a shifting hydraulic line that is a hydraulic source of the shifting hydraulic mechanism to an oil pressure at which shifting control can be performed by the shifting hydraulic mechanism till the transmission of power between the input disk and output disk is interrupted when the operation of the oil pump is stopped.

A toroidal variable speed traction drive includes a driving disc and a driven disc. The discs have a common axis. A plurality of pairs of contacting rollers are interposed between the discs. The discs are urged together against the roller pairs (A) by a clamping force. Each of the rollers has a first rolling surface, by which it rolls on the other roller of the pair, and a second rolling surface by which it rolls on the toroidal surface of a corresponding disc. Each roller is mounted on a supporting axle about which it can rotate. The rotational axes of the rollers in a pair are supported in a plane that contains the two points where the rollers of the pair contact the discs. At least one of the rollers in each pair is adapted to be moved to adopt a stable position within the plane by the reactionary force exerted on it by the other roller of the pair.

An apparatus for controlling a variator having at least one roller between two toroidal disks may include at least one actuator responsive to fluid pressure at separate high side and low side fluid inlets thereof to control torque applied by the at least one roller to the disks. First and second variator switching valves may each receive a first fluid at a first pressure and a second fluid at a second lesser pressure. The first and second variator switching valves supply the first fluid to the high side fluid inlet and the second fluid to the low side fluid inlet during two of four different operational states together defined by the variator switching valves, and supply the second fluid to the high side fluid inlet and the first fluid to the low side fluid inlet during each of the remaining two of the four different operational states.

A toroidal continuously variable transmission of the present invention comprises: input side disks (1a, 1b) and output side disks (6) being supported concentric with each other such that the disks can rotate freely; a trunnion (9) that comprises end sections (36) on both ends on which tilt shafts (13) that are concentric with each other are provided, and a support beam section (15) that extends between both end sections (36), the trunnion (9) being capable of pivotally displacing around the tilt shafts (13); a thrust rolling bearing (17); and a power roller (8) that is supported to the inside surface of the trunnion (9) by way of the thrust rolling bearing (17) such that it rotates freely; wherein the support beam section (15) comprises an inside surface having a cylindrical convex surface (14); the thrust rolling bearing (17) comprises an outer race (18a) having an outside surface with a concave section (19a) that fits with the cylindrical convex surface (14) of the support beam section (15), and a plurality of rolling bodies (26) that are located between the power roller (8) and a track of an outer race (18a); and the concave section (19a) of the outer race (18a) has side surface sections (29) on both sides in the width direction, fits with the cylindrical convex surface (14) by the cylindrical convex surface (14) coming in contact with both side surface sections (29).

A toroidal traction drive has an axial loading system with a primary loading component and a non-linear cam roller loading component.

The invention relates to the quantitative measurement of steroidal compounds by mass spectrometry. In a particular aspect, the invention relates to methods for quantitative measurement of steroidal compounds from multiple samples by mass spectrometry.

Monoclonal antibodies (mAbs) having thyroid stimulating activity (TSAb), especially full or considerably agonistic activity, or thyroid blocking activity (TBAb), which are obtainable by genetic immunization of mice, or fragments (F(ab')2, Fab or Fv) or humanized forms of such monoclonal antibodies or single chain forms (SCA; scFv) of such fragments, which antibodies, or their fragments, compete with bovine TSH for epitopes of the human TSHr, compete with autoantibodies from sera from Graves' patients as well as with autoantibodies from sera from patients harboring blocking autoantibodies for epitopes of the human TSHr, bind to conformational epitopes of the human TSHr located in the first 281 amino acids of the human TSHr, and usually also bind to TSFR receptors (TSHr) from different animals. Various uses of such antibodies, or of peptides corresponding to variable regions of such antibodies, are also described and claimed.

The spiroid wing tip according to embodiments of the invention including a continuous segmental assembly having a closed loop frontal profile comprising a lower near vertical segment, a horizontal segment, a vertical segment, a second horizontal upper segment, and a near vertical segment. Accordingly to some embodiments of the invention, the spiroid profile is lowered with respect to the wing chord plane, such that a portion of the spiroid wing tip extends below the wing chord plane.

Provided is bearing steel excellent in workability after spheroidizing-annealing and in hydrogen fatigue resistance property after quenching and tempering. The bearing steel has a chemical composition containing, by mass %: 0.85% to 1.10% C; 0.30% to 0.80% Si; 0.90% to 2.00% Mn; 0.025% or less P; 0.02% or less S; 0.05% or less Al; 1.8% to 2.5% Cr; 0.15% to 0.4% Mo; 0.0080% or less N; and 0.0020% or less O, which further contains more than 0.0015% to 0.0050% or less Sb, with the balance being Fe and incidental impurities, to thereby effectively suppress the generation of WEA even in environment where hydrogen penetrates into the steel, so as to improve the roiling contact fatigue life and also the workability such as cuttability and forgeability of the material.

Non-naturally occurring peptides are provided that act as a Src SH2 domain antagonist of cardiotonic steroids. Pharmaceutical compositions comprising the peptides are also provided along with vectors encoding the peptides. Methods of treating a Src-associated disease and reducing Src activity in a cell are further provided and include administering or contacting a cell with an effective amount of the peptide.

One embodiment of the present invention relates to a machine for sewing, embroidering, quilting and/or the like. Another embodiment of the present invention relates to a method for sewing, embroidering, quilting and/or the like. In one example, the present invention may be applied (e.g., as a machine and/or method) to a multi-needle machine or method. In another example, the present invention may provide for automatic lower (or bottom) thread cutting. In another example, the present invention may provide for automatic lower (or bottom) thread cutting by utilizing the phase (that is, movement phase) of a return of a looper (or hook) to cut the lower (or bottom) thread.

Method for creating a crystal/rhinestone template utilizing a sewing/embroidery machine to perforate a medium in a desired pattern. In the case of a multiple-needle sewing/embroidery machine, the machine's needle is replaced by a perforator blade and perforator blade holder which are attached to machine's needle bar. Machine's needle plate is replaced by perforator plate and waste holder. With a single-needle sewing/embroidery machine, machine's needle is replaced by a pressing tool attached to the machine's needle bar. A contact point, a spring, and an arm are attached to machine's presser foot. Machine's needle plate is replaced by perforator plate. A template medium is placed on a work surface of machine. Machine is operated by software that reads a user-specified pattern/motif outline for filling stones in vector form, using innate rules to move machine frame and control hole placement.

An embroidery data processor includes a color information acquiring unit configured to acquire color information of a workpiece cloth on which an embroidery pattern composed of a plurality of color-based pattern portions is sewn, a color storage unit configured to store data of defined colors, an assignment unit configured to randomly extract colors from the colors stored by the color storage unit for every color-based pattern portion, the extracted colors being used as thread color data specifying colors of the color-based pattern portions respectively, the assignment unit assigning the extracted colors to the respective color-based pattern portions, and a setting unit configured to set a predetermined extraction range containing a similar color or a contrast color based on the color information acquired by the acquiring unit. The assignment unit is configured to extract the color stored by the color storage unit in the set extraction range.

A embroidery clamp for thick fabric includes a movable clamping window support that is pivotally connected to a frame and extends around a pivotal axis. An actuating system applies a force to the end of the clamping window support and rotates the support around to pivotal axis to move clamping windows together. The clamping window supports have resilient properties and are configured for flexure.

An embroidery hoop includes a first frame, a second frame and a resilient member. The first frame includes an inner surface and an outer surface. A second frame includes an inner surface, an outer surface and a split portion. The split portion of the second frame includes a pair of separate end portions. One of the first and second frames is positionable in circumscribing alignment with the other of the first and second frames. The resilient member spans the end portions of the second frame split portion and is operable to provide a biasing force for abutting the inner surface of one of the first and second frames against the outer surface of the other of the first and second frames when the first and second frames are in circumscribing alignment.

An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.

Minecraft's blocky appearance may at first appear primitive and like a game of yesteryear, but they're in fact the building blocks of which a player is bestowed god-like creative powers, shackled only by the limitations of their own mind.

EVER fancied being a shepherd in a steampunk environment, filled with perilous danger which wouldn’t be out of place in a Saw movie?

IT’S been three months since we were treated to the rip-roaring hilarity-fest which was the opening episode of Tales from the Borderlands. It’s been a long wait.

As a penniless wanderer making landfall in The Trail: Frontier Challenge, you have one thing to do: push the thumbstick forward and hike to the next camp.

YOUNG motorcycle racing starlet Brody Crockford made a dramatic return to the British Junior Supersport series.

Earlier this Month vocalist Roberta Gambarini visited Detroit to be the judge for Detroit Jazz Festival Vocal Competition and appear at The Dirty Dog Jazz Café. She also visited WEMU to share her Italian and international jazz life story as well as her admiration for jazz masters such as Hank Jones and Jimmy Heath. She also brought her most recent CD “Connecting Spirits”.

Couldn't make it to this year's Detroit Jazz Festival? You can catch all the highlights from WEMU hosts and staff from the 2016 Detroit Jazz Festival right here!