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The Lancet Rheumatology: Small observational study of patients with severe COVID-19 treated with the arthritis drug anakinra finds clinical improvements

The first study to report use of the rheumatoid arthritis drug anakinra to treat COVID-19 patients found that high-dose anakinra was safe and was associated with respiratory improvements and reduced signs of cytokine storm [1] in 72% (21/29) of patients, according to results from patients studied for 21 days (enrolled from 17 to 27 March 2020) in a Milan hospital, published in The Lancet Rheumatology journal.




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Treatment for Diverticulitis -- updated ASCRS Guidelines published in Diseases of the Colon & Rectum

Reflecting research-driven changes in clinical practice, a revised set of evidence-based recommendations for the medical and surgical treatment of left-sided colonic diverticulitis has been published in Diseases of the Colon & Rectum (DC&R), the official journal of the American Society of Colon and Rectal Surgeons (ASCRS). The journal is published by Wolters Kluwer.




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Traffic pollution drops in lockdown -- but other risks revealed by Manchester experts

Traffic pollution for most parts of the UK is plummeting thanks to the COVID-19 lockdown but more urban ozone -- a dangerous air pollutant which can cause airway inflammation in humans -- is probably being generated, say experts from The University of Manchester. Observations in cities across the UK show marked decreases in nitrogen oxides but with corresponding increases in ozone during lockdown.




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Dearth of medical resources in Africa for COVID-19 reminiscent of early HIV/AIDS pandemic

'We have seen this before.' Global health scholars have issued a clarion call about the needless loss of life expected because of a foreseeable prospect of 'slow and inadequate access to supplies' to control COVID-19 in sub-Saharan Africa. They say what is unfolding now is similar to when lifesaving diagnostics and treatments came to the region long after they were available elsewhere.




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Controlling quantumness: Simulations reveal details about how particles interact

A recent study at the Okinawa Institute of Science and Technology Graduate University has described new states that can be found in super-cold atom experiments, which could have applications for quantum technology.




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Ancient DNA paints genetic portrait of Andes civilizations

An international team of researchers including the University of Adelaide, has completed the first large-scale study of DNA belonging to ancient humans of the central Andes in South America and found early genetic differences between groups of nearby regions, and surprising genetic continuity over thousands of years.




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Disproportionate burden of COVID-19 for immigrants in the Bronx, New York

The authors explain why COVID-19 presents a greater burden for immigrant communities and this article advocates for a more equitable health care system.




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Neandertals were choosy about making bone tools

Evidence continues to mount that the Neandertals, who lived in Europe and Asia until about 40,000 years ago, were more sophisticated people than once thought. A new study from UC Davis shows that Neandertals chose to use bones from specific animals to make a tool for specific purpose: working hides into leather.




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Transporting energy through a single molecular nanowire

Photosynthetic systems in nature transport energy very efficiently towards a reaction center, where it is converted into a useful form for the organism. Scientists have been using this as inspiration to learn how to transport energy efficiently in, for example, molecular electronics. Physicist Richard Hildner from the University of Groningen and colleagues have investigated energy transport in an artificial system made from nanofibres. The results were published in the Journal of the American Chemical Society.




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OSU study shows grange a 'natural partner' for expanding health outreach

In the ongoing struggle to address health care disparities in rural communities across the US, a recent study found that the perfect partner may be hiding in plain sight. The grange, founded in 1867, is a community-based organization that is likely familiar to anyone who's spent time in a small town. In addition to political advocacy on behalf of farmers, the grange's missions around community and family also align closely with the goals of public health.




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'Detailed' plans being drawn up to restart economy, Jenrick says as testing falls below 100,000 for fourth day

The update comes after Prime Minister Boris Johnson confirmed he would set out a lockdown exit strategy on Sunday.




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Debenhams accused of 'stealing' as retailer demands 90% discount on clothes from suppliers already at UK ports

ITV News has seen correspondence from Debenhams’ administrator to Bangladeshi suppliers demanding a 90% discount on garments orders.




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New Banksy artwork pays tribute to NHS heroes

The piece, called Game Changer, is on display in a corridor at Southampton General Hospital.




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Four-year-old with cancer reunited with father after seven weeks kept apart in lockdown

Mila Sneddon hasn't seen her father in seven weeks in order to keep her safe during coronavirus lockdown.




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Care company launch own We Care badge to support workers during coronavirus pandemic

A North East based care provider, Wellburn Care Homes, has launched their own We Care badge aiming to show support for care workers.




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Portrait of Dame Vera Lynn unveiled to mark VE Day

The oil on canvas painting is entitled The Enduring Sweetheart.




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Many parents of young children will be in greater debt after pandemic – report

Half of parents with young children will struggle to make ends meet in the next three months, study suggests.




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Report appears to show link between Covid-19 and a rare inflammatory syndrome seen in children

A report published in The Lancet appeared to show there was a link between Covid-19 and a deadly syndrome that affects some children.




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Passengers told to wear face coverings and gloves at some of UK's busiest airports

Limited temperature screening will also be trialled at the airports in coming weeks.




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UK coronavirus death toll increases to 30,615 as further 539 deaths confirmed

Dominic Raab announced the latest figures during the daily briefing.




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Spread of coronavirus in hospitals and care homes is the big problem, writes Robert Peston

In the community, the rate of transmission is probably as low as 0.5/0.6, which means its progress through the population has been arrested.




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Legal proceedings launched against Andrew ‘over unpaid ski resort bill’

Le Temps newspaper says the chalet was bought in 2014.




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Queen’s televised addresses just weeks apart

The monarch will speak to the nation on Friday to mark 75 years since VE Day.




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Fart leads police to hiding man

Officers heard a noise ‘believed to be the sound of someone breaking wind from a nearby bush’.




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Exclusive: Hospices to receive government supplies of PPE after warning of chronic shortages

Hospices are set to receive weekly supplies of critical personal protective equipment from the government.




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Our royal team on Kate's photography project and Princess Charlotte's birthday

In this week's Royal Rota, our team discuss the Duchess of Cambridge's latest volunteer work and Princess Charlotte birthday celebrations.




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Captain Tom Moore shares memories of wartime in VE Day ITV documentary

Captain Tom Moore has shared his memories of wartime in a special ITV documentary, Captain Tom's War.




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Cars could ‘talk’ to each other to warn of dangers using 5G, experts predict

Researchers said a vehicle-generated early warning system that alerts drivers is feasible within the next few years using 5G.




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UK weather: Temperatures could hit 26C in parts of the country

Southern parts of the UK will be fine, warm and dry.




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Transport Secretary Grant Shapps announces £2bn package to boost cycling and pedestrian capacity

The Secretary of State will be joined at Downing Street with deputy chief medical officer Professor Jonathan Van-Tam.




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Coronavirus: Further 346 people die after testing positive for Covid-19 in UK

Officials have urged Britons to follow lockdown rules during the sunny weekend.




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Trump ditches Easter goal, as US expert predicts up to 200,000 deaths

Donald Trump's announcement to extend coronavirus controls came as his infectious disease expert Anthony Fauci predicted up to 200,000 Americans could die of the coronavirus.




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Human rights clampdown as virus spreads in south-east Asia: experts

Authoritarian leaders across south-east Asia are putting tighter controls on their citizens as the coronavirus spreads and infections rise.




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'Shoot them dead': Duterte threatens people who defy lockdown

The Philippine President's anti-drug campaign has resulted in thousands of extra-judicial killings. He's now turned his attention to the coronavirus pandemic.




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As Italy teeters, EU wrestles with crisis that could tear it apart

It might be remembered as one of the most consequential calls for help in modern European history. 




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Coronavirus economy is already hurting Trump's re-election chances, economists say

Still, it's an open question whether the economy will ultimately doom Trump in November. One election model still predicts a Trump victory by a wide margin.




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Organised effort helping drive 5G coronavirus conspiracy theory

One Qatar-based researcher analysed 22,000 recent interactions on Twitter and found a large number of accounts displayed "inauthentic activity."




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Boris Johnson 'able to do short walks' but UK Prime Minister's recovery only just beginning

Johnson's father Stanley said his son's illness "got the whole country to realise this is a serious event".




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Abortion providers ask Supreme Court to intervene after Texas ban

The urgent intervention was sought after appeal courts twice ruled that special coronavirus laws meant only women who might not be able to receive an abortion before the state's 22-week limit could receive a waiver.




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Trump retweets call to fire Anthony Fauci after the coronavirus expert says quicker response 'could have saved lives'

President Donald Trump retweeted a call to fire his top infectious disease specialist Anthony Fauci Sunday evening, amid mounting criticism of the federal response to the coronavirus pandemic.




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Kim Jong-un raises sister's profile with North Korean Politburo post

Part emissary, part personal assistant, Kim Yo-jong was reinstated to her position as an alternate Politburo member of the ruling Workers' Party of Korea.




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Experts defend New Zealand's strict lockdown rules in face of criticism

As the number of new coronavirus cases drop, a group of academics said the government's lockdown plan is out of proportion with the health risks posed by virus.




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Pandemic gives Arthur Sinodinos 'baptism of fire' as US ambassador

Our man in Washington is making new friends at a safe distance.




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'Immunity passport' to free recovered Chileans from lockdown

Critics warn against moving too quickly with a medical union secretary saying: "There are serious doubts over existence of long-term immunity to this virus."




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South Korea plays down reports Kim Jong-un is near death

Officials in Seoul say they have not seen any unusual activity in North Korea, following reports North Korean dictator Kim Jong-un was gravely ill.




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Tamil family on Christmas Island wins Federal Court case

A Tamil asylum seeker family detained on Christmas Island has won a legal battle in the Federal Court, which found two-year-old Tharunicaa was denied procedural fairness.




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"Very messy": Principals question premier's part-time learning plan

Premier Gladys Berejiklian wants students to resume learning under a roster system, but principals have slammed the idea as confusing and unrealistic




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'Very messy': Principals question Premier's part-time learning plan

Premier Gladys Berejiklian wants students to resume learning under a roster system, but principals have slammed the idea as confusing and unrealistic.




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Company 'knew' virus was running rampant on Ruby Princess, court told

In a series of explosive allegations, Princess Cruises has been accused of recklessly endangering lives.




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Pandemic is an opportunity to entirely rethink university education

Students ought to be allowed to sample lectures to find which path best suits them before they put money down.