An article of footwear including a full monofilament upper is described. The full monofilament upper incorporates a knitted component including a monofilament knit element. The monofilament knit element is formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures. A fusible strand may be knit with the monofilament knit element. Upon heating, the fusible strand can combine and surround the monofilament strand within the monofilament knit element.

An article of footwear including a knitted component having a monofilament knit element with peripheral knit portions is described. The knitted component includes a monofilament knit element formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures.

A knit fabric for use as a wrap around-sleeve having connectors along opposed edges. The fabric comprises a body portion knitted in a single layer of warp and weft yarns, a first edge portion of warp and weft yarns formed into spaced chains which secure a woven tape having hooks onto the knit fabric and a second edge knit to form raised loops. The hooks secured along the first edge are adapted to secure with the loops along the second edge securing the fabric edges forming the fabric into a wrap-around sleeve.

An air belt having mesh webbing sufficiently strong and sufficiently expandable in the circumferential direction of a bag-shaped belt and an air belt apparatus including the air belt are provided. An air belt includes a folded member being a bag-shaped belt folded in a band shape and mesh webbing covering the folded member of the bag-shaped belt. The mesh webbing hardly expands in the longitudinal direction of the air belt, and is flexibly expandable in the circumferential direction of the bag-shaped belt. The mesh webbing is made of a raschel-knitted material. The knitted material is arranged such that the extending direction of knot portions of yarn threads and corresponds to the longitudinal direction of the air belt.

There is described herein a knitting technique for creating a garment having one or more 3D textile electrodes integrated therein. The knitting technique involves knitting the item with integrated electrodes and transmission channels in one single step. The electrode is knit using conducting thread while a base fabric is knit using non-conducting thread. The electrode is knit on a first needle bed and the base fabric is knit on a second needle bed opposite to and facing the first needle bed, the two needle beds being separated by a few millimeters. During the knitting process, the surface knit on the first needle bed and the surface knit on the second needle bed may be linked using an isolating thread network that is simply deposited, without forming a mesh, on the fabric, in order to provide the three-dimensional effect.

An apparatus for preparing a melon juice concentrate, such as watermelon juice concentrate, includes a finisher with brushes for separating melon flesh from melon rind including leaving at least 1/16 inch flesh on the rind and screens for separating juice from flesh. The apparatus also includes a steamer to reduce bacteria count on whole melon, a chopper for chopping melons into pieces less than about 16 inches square, an extractor for extracting juice from the flesh, and an evaporator for concentrating melon juice to form melon juice concentrate. The steamer includes a cylinder frame, steam jets directing steam through apertures in the cylinder frame at whole melon therein, and a motivator to move the whole melon along the cylinder frame. The apparatus can also process cantaloupe, honeydew melon, and other melon.

A two stage scrubber process for ethanol fermentation has a first stage using fusel oil to remove the hazardous air pollutants and recover the majority of the ethanol. A second stage uses water as the scrubbing solvent to recover any residual ethanol that is stripped from the first stage.

A beverage flavoring apparatus comprising of an elongated tubular body, having at least three elongated hollow sections and a container for holding liquid flavor. The top hollow section is for suction and at least one of the hollow sections is adapted to receive liquid flavor and it has a smaller cross sectional area and shorter length which enables the flavoring liquid to be introduced into the beverage stream in minute quantity. The other hollow section is adapted to receive beverage. The container is mounted or loaded on the elongated tubular body so that the section adapted to receive liquid flavor is immersed in the liquid flavor while the other hollow section is dipped in a beverage. As oral suction is being applied, both the liquid flavor and the beverage are drawn up the tubular body and mixes at the hollow suction end before ingestion.

A multi-functional electric cooker includes a heating boiler body (1) and a cover (2). The cooker also includes a rice soup collecting container (3) which is mounted between the heating boiler body (1) and the cover (2), a sealing ring (7) which is set between the rice soup collecting container (3) and the heating boiler body (1), and a rice soup sucker (6). An opening of one end of the sucker is located at the bottom of the rice soup collecting container (3) and the height of the opening is adjusted along with the amount of the rice in the heating boiler body. An opening of the other end of the sucker is located in the rice soup collecting container (3).

A shell cracking and retaining device for cracking shelled food products, wherein the device entirely or substantially retains food, shell portions and other debris during the cracking process, and therefore prevents said food, shell portions and other debris from being sent airborne from the device.

The two-piece electric coffee maker includes a Dallah (a traditional Arabian coffee pot for making Arabian coffee) and an electric stove. The coffee pot has a temperature sensor that extends from the base of the coffee pot handle into the pot. The base of the handle also has an electrical connector extending downward from the handle. The electric stove has a housing, a ceramic heating element or plate, a display console, and a mating electrical connector facing upward so that the connectors engage each other when the pot is placed on the heating element. An electronic control unit in the stove housing regulates boiling water for the coffee, reducing the heat after the water has started to boil, annunciating an alarm signal when the temperature of the water is suitable to add coffee grounds to the pot, and monitors brewing time for the coffee.

The invention relates to a capsule for the preparation of a beverage. The capsule includes first and second covering walls connected for forming a cavity containing a beverage ingredient and a contactless identifying element for identifying the capsule by detecting the identifying element using the detector of a beverage producing device. The identifying element is preferably disposed in the cavity.

The present invention relates to a device to regulate the level of a liquid inside a boiler of a coffee machine, having a transparent duct connected to the boiler and designed to visibly display the level of the liquid inside the boiler, a capacitive sensor that can be positioned outside the transparent duct in determined positions and designed to generate electric signals representing the presence or absence of liquid in correspondence to the position of the sensor along the transparent duct. The sensor of the device has first measuring elements and second measuring elements, both of capacitive type; the second measuring elements are positioned at a predetermined distance from the first measuring elements, and a measuring device designed to measure the impedance between the first and second measuring elements and to generate signals indicating the presence or absence of liquid in correspondence to the position of the sensor. The invention also relates to the machine that includes this device.

The invention provides a new method for preparing ultra-small polymeric-lipidic delivery nanoparticles (USDNs) that were synthesized by a nanoprecipitation method followed by a layer-by-layer nanodeposition. The USDNs particle size can be controlled between 5-25 mn and provides loading capacities of 22.12% to 72.08%. Moreover, the USDNs platform provides pH controlled drug release, within a terminal release ratio of 68% at pH 5.0 and almost no release to pH of 7.5. Furthermore, based on their small sizes (5-25 nm) and unique composition, the USDNs penetrates the skin strata efficiently, release the payload at the target site as topical or transdermal treatment of a variety of skin disorders. Additionally the USDNs system can be used to treat and diagnoses other crucial diseases (Cancer, Alzheimer, etc) can be combined with various micro-needles or needles free array technologies for special application.

A peptide comprising a sequence for opening a tight junction of an epithelial surface and optionally a cell penetrating sequence; and related compositions, optionally comprising further pharmaceutical agents; and related methods.

The invention provides compositions and methods for treating leukemia, for example, acute myeloid leukemia (AML) and B-cell acute lymphoid leukemia (B-ALL). The invention also relates to at least one chimeric antigen receptor (CAR) specific to CD123, vectors comprising the same, and recombinant T cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD123 binding domain. The invention also includes methods of bone marrow ablation for use in treatments necessitating bone marrow reconditioning or transplant.

Described herein are doppel-targeting molecules useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with pathological angiogenesis, such as tumors, cancers, atherosclerosis, tuberculosis, asthma, pulmonary arterial hypertension (PAH), neoplasms and neoplasm-related conditions, and for detecting doppel expression in a subject. Related compositions and methods also are described.

Provided herein are methods of treatment to regenerate, restore or rejuvenate a tissue. Methods include making adult somatic and germ cells pluripotent for administration to a patient. Alternatively, created pluripotent cells may be differentiated to the desired tissue type and administered to a patient to repair or enhance the target tissue.

Non-naturally occurring peptides are provided that act as a Src SH2 domain antagonist of cardiotonic steroids. Pharmaceutical compositions comprising the peptides are also provided along with vectors encoding the peptides. Methods of treating a Src-associated disease and reducing Src activity in a cell are further provided and include administering or contacting a cell with an effective amount of the peptide.

The present invention concerns cancer biomarkers. In particular, the invention concerns HGF as a biomarker for patient selection and patient prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.

The present invention provides methods for assessing whether a subject is at risk of developing a neurological disorder, diagnosing or confirming whether a subject is afflicted with a neurological disorder, assessing whether PD has progressed in a subject afflicted with PD, assessing whether a neurological disorder is developing in a subject who has been identified as being at risk of developing the neurological disorder, assessing whether a subject afflicted with a neurological disorder is likely to benefit from a therapy, assessing whether a subject afflicted with a neurological disorder has benefited from a therapy, treating a subject afflicted with a neurological disorder, and prophylactically treating a subject who has been identified as being at risk of developing a neurological disorder. The present invention also provides epitopes, compounds and compositions relating to these methods.

Applicant's invention relates to a process and apparatus for the high speed welding in large quantities of various geometric shaped jump rings to buttons, pendants and other jewelry by utilizing composite jump ring apparatus having first and second projections extending from the jump rings at different locations so that they may function in automatic welding machines.

Disclosed is a wireless surround sound speaker system wherein a transmitter broadcasts a variety of FM signals that correspond to the individual speaker channels commonly found in a surround sound system. Receivers, individually equipped with signal receiving, conditioning and amplification components, are configured to receive any one of the broadcast signals in a remote location and are used to drive a conventional loudspeaker in that location. Powered by wall socket or via DC battery packs, the receivers, used in conjunction with the transmitter, provide surround sound capabilities without the need for complex and difficult wiring.

A button system and method of manufacturing the same are provided for identifying fiber from which an article of apparel is manufactured. Initially, an article of apparel manufactured with a predetermined fiber is identified. Next, indicia indicative of the predetermined fiber is selected. Next, at least one button is manufactured with the indicia thereon for identifying the fiber from which the article of apparel is manufactured.

A machine manufactures buttons having coplanar shell flanges in a two-stroke operation. The machine comprises a crimp die having different resistances to advancement of a ram. The first resistance enables a metal shell margin to partially bend under a flat back that is placed on a first surface of the crimp die. The second resistance enables the shell wall to completely bend against a second surface of the crimp die so as to form flanges that lie in a single plane. Both round and rectangular buttons are manufacturable using the same basic machine. The rectangular machine uses a shifter cage on the ram that rotates in response to indexing a die table on which the crimp die and a pickup die are attached. The round machine uses a rotatable frame on the ram. With the rectangular machine, the shell is initially bent during a pickup stroke of the ram.

A button, knob or control key with an etchable support plate which is engraved on the backside with a fine symbol by laser, erosion or mechanical engraving, which only cuts into the material of the support plate, but not through the support plate. The backside of the support plate is optionally coated. A foil is applied on the laminated layer and affixed thereto. The front side of the support plate is treated with a material-removing substance. The material removal with the material-removing substance is performed until the engraving extending into the support plate is at least partially or completely exposed on the front side. Application of a protective layer to the front side of the support plate from which the material was removed. A function symbol is provided on the button such that it can be backlit. It is engraved in a fine line width providing a sharp optical definition erosion, mechanical engraving.

A soy protein product having a protein content of at least 60 wt % (N×6.25) d.b., preferably an isolate having a protein content of at least about 90 wt % (N×6.25) d.b., is formed from the supernatant from the precipitation of a soy protein micellar mass. A calcium salt or other divalent salt is added to the supernatant, before concentration, after initial concentration or after final concentration, to provide a conductivity of about 2 to about 30 mS. Precipitate is removed from the resulting solution and the pH of the clear soy protein solution is optionally adjusted to about 1.5 to about 4.4. The optionally pH-adjusted clear solution is concentrated to a concentration of about 50 to about 400 g/L and the clear concentrated protein solution is optionally diafiltered prior to drying. The soy protein product is soluble in acidic media and produces transparent, heat stable solutions at low pH values and, therefore, may be used for protein fortification of soft drinks and sports drinks.

The present disclosure relates to a method and a device for producing food products, in particular sleeveless products of a specific form with the following steps: entry of form parameters, display of the form of the food product as a function of the entered form parameters as a 2D or 3D graphic, calculation of process parameters as a function of the entered form parameters.

The brewing system disclosed herein includes a spinning or rotating inlet nozzle for use in intermixing hot water and coffee in a coffee cartridge. The inlet nozzle may include one or more flow ports that inject hot water into an inner chamber of the coffee cartridge at select angles, locations and pressures to create the desired fluidized mixture of hot water and beverage medium. Such an inlet nozzle may be adapted for use in commercial coffee brewers and the amount of coffee brewed may be user regulated with an external indicator dial coupled to a controller-regulated rheostat that governs fluid flow to the brewer head by taking readings from a pump, flow meter or strain gauge.

The present invention is directed to novel organoleptic compounds, a process of augmenting, enhancing or imparting taste to a material selected from the group consisting of a foodstuff, a chewing gum, a dental product, an oral hygiene product and a medicinal product comprising the step of incorporating an olfactory acceptable amount of such novel organoleptic compounds, and a process of improving, enhancing or modifying a fragrance composition through the addition of an olfactory acceptable amount of such novel organoleptic compounds.

A formulation consisting of a food-grade dye and a plant aroma cocktail is uptaken by plants and flowers and fruit. The improved aroma profile and color make the plant or it's flowers or it's fruit more desirable for consumption or viewing with an enhanced aroma.

Disclosed herein is a nutrient delivery system that provides a nutritional formula for consumption. The nutrient delivery system includes a pod and a nutritional powder comprising at least one phospholipid. The nutritional formula has improved characteristics, such as decreased foaming.

A wireless small motor driver, in which power consumption is decreased by adjusting a gear ratio, the efficiency of an operation is increased due to a high torque, and the safety of a worker at night is ensured using an illumination lamp. The wireless small motor driver includes a driver case inside of which a motor is provided. A driver bit has a predetermined length in a bilateral direction, the driver bit being replaceable, with one or both ends thereof conforming to the shape of a bolt, and has a fixing projection. A socket is coupled to an end portion of the driver case, the driver bit being fastened to the socket. A rotation reduction gear is coupled to the motor, the rotation reduction gear transmitting rotary force to the socket and increasing a torque. A USB and a battery for supplying uniform power to the motor are added.

A power tool, in particular a hand-held power tool, preferably embodied as a cordless screwdriver, is equipped with a torque limiting unit in which the release torque is settable by way of a locking brace that is equipped with a spring brace for locking elements that abut axially against parts of a planetary drive, in particular the ring gear thereof or the planet carrier thereof as a last gear stage, the spring elements of the spring brace and the locking elements being located with a radial offset from one another.

The invention relates to a guiding device for guiding an oblong intermediate element while joining at least two decorative elements by means of this intermediate element.

A thread hook and a looper thread holder are arranged on a rear side of a needle drop position of a sewing machine. When usual sewing is completed, the thread hook and the looper thread holder swing and move close to a looper. A hook part provided at a tip end of the thread hook holds a needle thread loop caught by the looper and positions it on an advance end side of the looper away from the needle drop position, and a thread receiving part provided at a tip end of the looper thread holder holds a looper thread extending from the looper to cloths and positions it on the front side away from the needle drop position. The sewing machine performs sewing for at least one stitch while maintaining positions of the needle thread loop and the looper thread.

Aspects and embodiments of the present invention are directed to systems and methods for embellishing fabric. In accordance with embodiments, a stitching system for a sewing machine is provided comprising a processor configured to control the sewing machine and a user interface configured to receive a stitch selection corresponding to a set of commands executable by the processor to instruct the sewing machine to sew the stitch selection. The set of commands may comprise a first command to sew a first portion of the stitch selection, a second command to stop sewing after completion of the first portion, and a third command to sew a second portion of the stitch selection after completion of the second command. The systems and methods of the present invention may advantageously allow an operator to create a running sequence of perfectly replicated embellishments.

An anti-ballistic shelter is provided. The antiballistic shelter includes a frame having two or more support members and one or more wall surfaces. The one or more wall surfaces include a flexible high strength layered anti-ballistic material attached to the frame. The flexible high strength layered anti-ballistic material is layered in at least two directions and is attached to the frame in an inverted T construction including a calculated stretch material portion, one or more breakaway stitches and one or more holding stitches.

A tension release device for compensating mechanical error of a tension device for a sewing machine includes a rotary arm, a tension release shaft, a guiding member, an actuating member, and a micro-adjustment member, the rotary arm is located at one end of the tension release shaft which is inserted through the base, the tension release shaft is coupled to the guiding member, the guiding member is provided with an arc-shaped guiding flange which includes a first end and a second end higher than the first end. On the actuating member is provided a push portion which protrudes toward and is pushed by the guiding flange of the guiding member, a micro-adjustment hole is formed at one end of the actuating member or at the one end of the control shaft, and the micro-adjustment member is screwed in the micro-adjustment hole and extends toward the tension release shaft.

A sewing apparatus and method therefor includes a drive mechanism, a thread feed mechanism, and a needle engagement mechanism for engaging the thread feed mechanism. The drive mechanism comprises a drive motor configured to transmit power from the drive motor to the needle engagement mechanism such that it drives a needle within a cartridge without moving the entire cartridge. A method and sewing apparatus includes a plurality of thread feed mechanisms and a needle engagement mechanism for selecting and engaging each of the thread feed mechanisms.

A method of dispensing adhesive onto a stretched elastic strand includes applying a first volume of adhesive onto a first portion of the elastic strand, applying a second volume of adhesive onto a second portion of the elastic strand, and applying a third volume of adhesive onto a third portion of the elastic strand. The second volume is less than the first and third volumes. When the elastic strand is adhered to a substrate to form a personal disposable hygiene product, the first and third portions of the elastic strand define opposing ends of the elastic strand, which are adhered with a larger amount of adhesive to resist creep at the opposing ends. The reduction of adhesive in the second or central portion between the opposing ends significantly reduces the adhesive add on in the personal disposable hygiene product.

A fuselage panel made of composite material having a skin with an opening, at least part of the contour of which is reinforced by an integrated reinforcement made of composite material. The fuselage panel includes at least one liner made of composite material which is attached to and superposed on the reinforced skin portion and participates at least partially in defining the contour of the opening, the panel additionally including consolidating members, each passing at least partially through the liner and at least partially through the reinforced skin portion.

A method for making a water-degradable paper sheet involves the following: providing at least one strip of a water-soluble binding material in the form of a dry film; providing at least two strips each made of at least one ply of cellulose wadding; placing the strip of water-soluble binding material between the two strips of cellulose wadding; humidifying, assembling and pressing the three strips; and drying the complex strip thus obtained. The sheet thus obtained can be used for making a roll carrier mandrel by helically winding one or more strips from the sheet about a cylinder. Articles produced from the sheet can particularly be used in the field of products for sanitary or domestic use.

A labelling machine comprising a supply spool support (12) adapted to receive a supply spool (28), a takeup spool support (14) adapted to form a takeup spool (32) of web (30) from which at least some labels (74) have been removed, a motor (40) arranged to turn the takeup spool, and a controller to control operation of the motor. A web path (16) is defined between the supply spool and the take-up spool, and the controller is arranged to control the motor to turn the take-up spool so as to cause controlled predetermined linear movement of a web along the web path and onto the take-up spool, furthermore comprising a sensor (50) operable to sense linear displacement of the web and/or displacement of the web in a direction other than the direction of the web, a printer (34) movable between a first position and a second position, and a separator surface (24) comprising a first portion inclined relative to the web path.

Positioning system of sectors of a device for producing an airplane fuselage in which a lamination mandrel comprises a plurality of sectors borne by a supporting structure and mobile along guides between: an expanded lamination position and a contracted disassembling position. Each guide comprises a fixed part borne by the supporting structure and a mobile part sliding along/with respect to the fixed part in a rectilinear direction H. Between a portion of each mobile part facing towards the respective sector and a stiffening structure of the sector a positioning device is provided which allows adjustment of the position of the sector with respect to the guide in two directions which lie in a plane RP perpendicular to the axis H of the guide.

A constraint system of sectors of a device for producing an airplane fuselage in which a lamination mandrel is adapted to receive and support a band of impregnated synthetic material. The lamination mandrel comprises a plurality of sectors angularly spaced about the axis and mobile between: an expanded lamination position and a contracted disassembling position. A constraint system is provided between each sector and the sectors adjacent thereto which guarantees a predetermined arrangement of the first sector with respect to the second sector adjacent thereto, preventing any translation along two directions which lie in an adjustment plane perpendicular to an axis RD which extends radially from the symmetry axis to the external surface.

A ceramic green sheet laminate is produced by stacking ceramic green sheets, each including conductive films for forming first or second internal electrodes on a surface thereof. A first cutting step is performed in which the ceramic green sheet laminate is cut to form first and second end surfaces at which the first or second internal electrodes are exposed. A second cutting step is performed in which the ceramic green sheet laminate is cut to form first and second side surfaces at which the first and second internal electrodes are exposed. In the second cutting step, the ceramic green sheet laminate is pressed and cut by moving a cutting blade in a length direction or a width direction.

The invention relates to the use of a hot-melt adhesive having high hardness for adhesive bonding of metal films or foils, paper films or foils, and/or plastic films or foils. The invention further relates to a method for adhesively bonding a metal film or foil, paper film or foil, and/or plastic film or foil onto a substrate.