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Stanford's Tara VanDerveer on Haley Jones' versatile freshman year: 'It was really incredible'

During Friday's "Pac-12 Perspective," Stanford head coach Tara VanDerveer spoke about Haley Jones' positionless game and how the Cardinal used the dynamic freshman in 2019-20. Download and listen wherever you get your podcasts.




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On Mahalanobis Distance in Functional Settings

Mahalanobis distance is a classical tool in multivariate analysis. We suggest here an extension of this concept to the case of functional data. More precisely, the proposed definition concerns those statistical problems where the sample data are real functions defined on a compact interval of the real line. The obvious difficulty for such a functional extension is the non-invertibility of the covariance operator in infinite-dimensional cases. Unlike other recent proposals, our definition is suggested and motivated in terms of the Reproducing Kernel Hilbert Space (RKHS) associated with the stochastic process that generates the data. The proposed distance is a true metric; it depends on a unique real smoothing parameter which is fully motivated in RKHS terms. Moreover, it shares some properties of its finite dimensional counterpart: it is invariant under isometries, it can be consistently estimated from the data and its sampling distribution is known under Gaussian models. An empirical study for two statistical applications, outliers detection and binary classification, is included. The results are quite competitive when compared to other recent proposals in the literature.




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Analyzing complex functional brain networks: Fusing statistics and network science to understand the brain

Sean L. Simpson, F. DuBois Bowman, Paul J. Laurienti

Source: Statist. Surv., Volume 7, 1--36.

Abstract:
Complex functional brain network analyses have exploded over the last decade, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has facilitated these analyses and enabled examining the brain as an integrated system that produces complex behaviors. While the field of statistics has been integral in advancing activation analyses and some connectivity analyses in functional neuroimaging research, it has yet to play a commensurate role in complex network analyses. Fusing novel statistical methods with network-based functional neuroimage analysis will engender powerful analytical tools that will aid in our understanding of normal brain function as well as alterations due to various brain disorders. Here we survey widely used statistical and network science tools for analyzing fMRI network data and discuss the challenges faced in filling some of the remaining methodological gaps. When applied and interpreted correctly, the fusion of network scientific and statistical methods has a chance to revolutionize the understanding of brain function.




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Models of tree and stand dynamics : theory, formulation and application

Mäkelä, Annikki, author
9783030357610




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Human behavior analysis : sensing and understanding

Yu, Zhiwen, author
9789811521096 (electronic bk.)




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Handbook of immunosenescence : basic understanding and clinical implications

9783319645971 (electronic bk.)




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Handbook of geotechnical testing : basic theory, procedures and comparison of standards

Li, Yanrong (Writer on geology), author.
0429323743 electronic book




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Gapenski's understanding healthcare financial management

Pink, George H., author.
9781640551145 (electronic bk.)




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Botulinum toxins, fillers and related substances

9783319168029 (electronic bk.)




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Aquatic biopolymers : understanding their industrial significance and environmental implications

Olatunji, Ololade.
9783030347093 (electronic bk.)




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Anxiety disorders : rethinking and understanding recent discoveries

9789813297050 (electronic bk.)




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Suntuity AirWorks Offering FREE Assistance in Drone Acquisition...

The drones and programs will be fully paid for by the DOJ as part of the $850 million funding that has been allocated to help public safety departments fight the spread of COVID-19. This includes...

(PRWeb April 30, 2020)

Read the full story at https://www.prweb.com/releases/suntuity_airworks_offering_free_assistance_in_drone_acquisition_through_850mm_federal_grant_assistance_program_for_public_safety_agencies/prweb17090555.htm




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Bootstrap confidence regions based on M-estimators under nonstandard conditions

Stephen M. S. Lee, Puyudi Yang.

Source: The Annals of Statistics, Volume 48, Number 1, 274--299.

Abstract:
Suppose that a confidence region is desired for a subvector $ heta $ of a multidimensional parameter $xi =( heta ,psi )$, based on an M-estimator $hat{xi }_{n}=(hat{ heta }_{n},hat{psi }_{n})$ calculated from a random sample of size $n$. Under nonstandard conditions $hat{xi }_{n}$ often converges at a nonregular rate $r_{n}$, in which case consistent estimation of the distribution of $r_{n}(hat{ heta }_{n}- heta )$, a pivot commonly chosen for confidence region construction, is most conveniently effected by the $m$ out of $n$ bootstrap. The above choice of pivot has three drawbacks: (i) the shape of the region is either subjectively prescribed or controlled by a computationally intensive depth function; (ii) the region is not transformation equivariant; (iii) $hat{xi }_{n}$ may not be uniquely defined. To resolve the above difficulties, we propose a one-dimensional pivot derived from the criterion function, and prove that its distribution can be consistently estimated by the $m$ out of $n$ bootstrap, or by a modified version of the perturbation bootstrap. This leads to a new method for constructing confidence regions which are transformation equivariant and have shapes driven solely by the criterion function. A subsampling procedure is proposed for selecting $m$ in practice. Empirical performance of the new method is illustrated with examples drawn from different nonstandard M-estimation settings. Extension of our theory to row-wise independent triangular arrays is also explored.




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Distance multivariance: New dependence measures for random vectors

Björn Böttcher, Martin Keller-Ressel, René L. Schilling.

Source: The Annals of Statistics, Volume 47, Number 5, 2757--2789.

Abstract:
We introduce two new measures for the dependence of $nge2$ random variables: distance multivariance and total distance multivariance . Both measures are based on the weighted $L^{2}$-distance of quantities related to the characteristic functions of the underlying random variables. These extend distance covariance (introduced by Székely, Rizzo and Bakirov) from pairs of random variables to $n$-tuplets of random variables. We show that total distance multivariance can be used to detect the independence of $n$ random variables and has a simple finite-sample representation in terms of distance matrices of the sample points, where distance is measured by a continuous negative definite function. Under some mild moment conditions, this leads to a test for independence of multiple random vectors which is consistent against all alternatives.




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Estimating the rate constant from biosensor data via an adaptive variational Bayesian approach

Ye Zhang, Zhigang Yao, Patrik Forssén, Torgny Fornstedt.

Source: The Annals of Applied Statistics, Volume 13, Number 4, 2011--2042.

Abstract:
The means to obtain the rate constants of a chemical reaction is a fundamental open problem in both science and the industry. Traditional techniques for finding rate constants require either chemical modifications of the reactants or indirect measurements. The rate constant map method is a modern technique to study binding equilibrium and kinetics in chemical reactions. Finding a rate constant map from biosensor data is an ill-posed inverse problem that is usually solved by regularization. In this work, rather than finding a deterministic regularized rate constant map that does not provide uncertainty quantification of the solution, we develop an adaptive variational Bayesian approach to estimate the distribution of the rate constant map, from which some intrinsic properties of a chemical reaction can be explored, including information about rate constants. Our new approach is more realistic than the existing approaches used for biosensors and allows us to estimate the dynamics of the interactions, which are usually hidden in a deterministic approximate solution. We verify the performance of the new proposed method by numerical simulations, and compare it with the Markov chain Monte Carlo algorithm. The results illustrate that the variational method can reliably capture the posterior distribution in a computationally efficient way. Finally, the developed method is also tested on the real biosensor data (parathyroid hormone), where we provide two novel analysis tools—the thresholding contour map and the high order moment map—to estimate the number of interactions as well as their rate constants.




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On the best constant in the martingale version of Fefferman’s inequality

Adam Osękowski.

Source: Bernoulli, Volume 26, Number 3, 1912--1926.

Abstract:
Let $X=(X_{t})_{tgeq 0}in H^{1}$ and $Y=(Y_{t})_{tgeq 0}in{mathrm{BMO}} $ be arbitrary continuous-path martingales. The paper contains the proof of the inequality egin{equation*}mathbb{E}int _{0}^{infty }iglvert dlangle X,Y angle_{t}igrvert leq sqrt{2}Vert XVert _{H^{1}}Vert YVert _{mathrm{BMO}_{2}},end{equation*} and the constant $sqrt{2}$ is shown to be the best possible. The proof rests on the construction of a certain special function, enjoying appropriate size and concavity conditions.




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Characterization of probability distribution convergence in Wasserstein distance by $L^{p}$-quantization error function

Yating Liu, Gilles Pagès.

Source: Bernoulli, Volume 26, Number 2, 1171--1204.

Abstract:
We establish conditions to characterize probability measures by their $L^{p}$-quantization error functions in both $mathbb{R}^{d}$ and Hilbert settings. This characterization is two-fold: static (identity of two distributions) and dynamic (convergence for the $L^{p}$-Wasserstein distance). We first propose a criterion on the quantization level $N$, valid for any norm on $mathbb{R}^{d}$ and any order $p$ based on a geometrical approach involving the Voronoï diagram. Then, we prove that in the $L^{2}$-case on a (separable) Hilbert space, the condition on the level $N$ can be reduced to $N=2$, which is optimal. More quantization based characterization cases in dimension 1 and a discussion of the completeness of a distance defined by the quantization error function can be found at the end of this paper.




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Distances and large deviations in the spatial preferential attachment model

Christian Hirsch, Christian Mönch.

Source: Bernoulli, Volume 26, Number 2, 927--947.

Abstract:
This paper considers two asymptotic properties of a spatial preferential-attachment model introduced by E. Jacob and P. Mörters (In Algorithms and Models for the Web Graph (2013) 14–25 Springer). First, in a regime of strong linear reinforcement, we show that typical distances are at most of doubly-logarithmic order. Second, we derive a large deviation principle for the empirical neighbourhood structure and express the rate function as solution to an entropy minimisation problem in the space of stationary marked point processes.




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Convergence and concentration of empirical measures under Wasserstein distance in unbounded functional spaces

Jing Lei.

Source: Bernoulli, Volume 26, Number 1, 767--798.

Abstract:
We provide upper bounds of the expected Wasserstein distance between a probability measure and its empirical version, generalizing recent results for finite dimensional Euclidean spaces and bounded functional spaces. Such a generalization can cover Euclidean spaces with large dimensionality, with the optimal dependence on the dimensionality. Our method also covers the important case of Gaussian processes in separable Hilbert spaces, with rate-optimal upper bounds for functional data distributions whose coordinates decay geometrically or polynomially. Moreover, our bounds of the expected value can be combined with mean-concentration results to yield improved exponential tail probability bounds for the Wasserstein error of empirical measures under Bernstein-type or log Sobolev-type conditions.




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Discover Protestant nonconformity in England and Wales / Paul Blake.

Dissenters, Religious -- Great Britain.




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Chaffetz: I don't understand why Adam Schiff continues to have a security clearance

Fox News contributor Jason Chaffetz and Andy McCarthy react to House Intelligence transcripts on Russia probe.





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'We Cannot Police Our Way Out of a Pandemic.' Experts, Police Union Say NYPD Should Not Be Enforcing Social Distance Rules Amid COVID-19

The New York City police department (NYPD) is conducting an internal investigation into a May 2 incident involving the violent arrests of multiple people, allegedly members of a group who were not social distancing





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Forget Black Booties, Amal Clooney and J.Lo Are Wearing This Weather-Resistant Boot Trend Instead

And it’s on sale at Nordstrom.




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A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

John D. Cahoy
Jan 2, 2008; 28:264-278
Cellular




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Endothelial Adora2a Activation Promotes Blood-Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance

Masaki Yamamoto
May 22, 2019; 39:4179-4192
Neurobiology of Disease




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Indigenous peoples and dementia : new understandings of memory loss and memory care

9780774837835 (hardcover)




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A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

John D. Cahoy
Jan 2, 2008; 28:264-278
Cellular




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Le Comité de Bâle finalise sa revue du traitement réglementaire des expositions aux actifs souverains sans modifier les règles existantes et publie un document de discussion

French translation of the press release about the Basel Committee publishing a discussion paper on "The regulatory treatment of sovereign exposures" (7 December 2017)




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Le Communiqué de Bâle finalise les principes relatifs aux tests de résistance, passe en revue les moyens pour mettre fin aux comportements d'arbitrage réglementaire, s'accorde sur la liste annuelle des G-SIB et discute du ratio

French translation of press release - the Basel Committee on Banking Supervision is finalising stress-testing principles, reviews ways to stop regulatory arbitrage behaviour, agrees on annual G-SIB list, discusses leverage ratio, crypto-assets, market risk framework and implementation, 20 September 2018.




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your job wont stand a chance!




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Coding of Navigational Distance and Functional Constraint of Boundaries in the Human Scene-Selective Cortex

For visually guided navigation, the use of environmental cues is essential. Particularly, detecting local boundaries that impose limits to locomotion and estimating their location is crucial. In a series of three fMRI experiments, we investigated whether there is a neural coding of navigational distance in the human visual cortex (both female and male). We used virtual reality software to systematically manipulate the distance from a viewer perspective to different types of a boundary. Using a multivoxel pattern classification employing a linear support vector machine, we found that the occipital place area (OPA) is sensitive to the navigational distance restricted by the transparent glass wall. Further, the OPA was sensitive to a non-crossable boundary only, suggesting an importance of the functional constraint of a boundary. Together, we propose the OPA as a perceptual source of external environmental features relevant for navigation.

SIGNIFICANCE STATEMENT One of major goals in cognitive neuroscience has been to understand the nature of visual scene representation in human ventral visual cortex. An aspect of scene perception that has been overlooked despite its ecological importance is the analysis of space for navigation. One of critical computation necessary for navigation is coding of distance to environmental boundaries that impose limit on navigator's movements. This paper reports the first empirical evidence for coding of navigational distance in the human visual cortex and its striking sensitivity to functional constraint of environmental boundaries. Such finding links the paper to previous neurological and behavioral works that emphasized the distance to boundaries as a crucial geometric property for reorientation behavior of children and other animal species.




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Understanding the true cost of malnutrition

Malnutrition isn’t just a problem of hunger in developing countries—it exists in all regions and across socio-economic classes. The effects on human health Besides undernutrition, malnutrition also includes micronutrient-deficient diets and overweight and obesity. Chronic malnutrition can have serious, often life-threatening, health consequences, especially for children. Undernutrition can lead to physical and cognitive stunting, and makes children more susceptible to infectious diseases. Micronutrient deficiencies [...]




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Whittling down instances of child labour in agriculture

“Children subjected to child labour need our support and action so they can enjoy their right to education and health and become productive farmers and workers as adults to escape poverty and hunger.” - José Graziano da Silva, FAO Director- General  Child labour is not unique to a particular country, ethnicity, culture, or ideology. Today, there are about 100 million boys [...]




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Antimicrobial resistance – What you need to know

An estimated 700 000 people die each year from antimicrobial resistant (AMR) infections and an untold number of sick animals may not be responding to treatment. AMR is a significant global threat to public health, food safety and security, as well as to livelihoods, animal production and economic and agricultural development. The intensification of agricultural production has led to a rising use of antimicrobials – a use that is expected to more than double by 2030. Antimicrobials are important for the treatment of animal and plant diseases [...]




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Green Climate Fund approves programmes to fight climate change in Chile, Kyrgyzstan and Nepal

The Board of the Full Article



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These Graphics Help Explain Why Social Distancing Is Critical

The positive outcomes won’t be immediately apparent, but will help reduce the strain on our healthcare system




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Archaeologists Unearth Remnants of Kitchen Behind Oldest House Still Standing in Maui

The missionary who lived in the house during the mid-1800s delivered vaccinations to locals during a smallpox epidemic




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Recall opponents seek to drop court fight: Stand Tall With Mike withdraws its appeal, gearing up for possible recall election




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As Face Mask Supply Dwindles, Fashion Designers Offer Their Assistance

In New York City, a desperate need among healthcare workers has pushed to the forefront the question: Is homemade equipment safe to use?




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When the Stanley Cup Final Was Canceled Because of a Pandemic

In 1919, a second wave of cases of the previous year's flu lead to the sudden death of the hockey championship




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How 'Social Distancing' Can Get Lost in Translation

Governments around the world grapple with how to deliver important guidelines on minimizing the spread of COVID-19




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Former champ Lance Mackey wiped from 2020 Iditarod standings over failed drug test

Veteran musher Lance Mackey has had his 21st place finish in this year's Iditarod Trail Sled Dog Race vacated because of a failed drug test, race officials announced Thursday.



  • News/Canada/North

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'They don’t understand what love is'

Noy shares her journey of experiencing God's love for herself and forgiving the community that persecuted her family.




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Standard Immunization of Mice, Rats, and Hamsters

Mice, rats, or hamsters are immunized by giving biweekly injections of a purified antigen, cultured cells, or cDNA. For mice, if a pure, soluble protein antigen is being used and is abundant, a dose of 50–100 µg in adjuvant at each immunization is a sensible general recommendation; for rats and hamsters, a dose of 100–200 µg is sufficient. Lower doses can be used for antigens with higher immunogenicity. Adjuvants (Freund's, Ribi, Hunter's TiterMax, ImmunEasy, or Alum) should be mixed with the immunizing antigen for the first two immunizations only; Complete Freund's adjuvant is only used with the first immunization. Subsequent immunizations are performed in phosphate-buffered saline (PBS) or normal saline, with or without Incomplete Freund's adjuvant. The choice of adjuvant is dependent on the subclass of immunoglobulin required. Over the course of the 6-wk immunization schedule, each animal usually receives a total of six injections (three subcutaneous and three intraperitoneal). Once a good titer has developed against the antigen of interest, regular boosts and bleeds are performed to collect the maximum amount of serum. For rats and hamsters, boosts should be spaced every 2–3 wk, and serum samples of 400–500 µL should be collected 10–12 d after each boost. For mice, boosts should be spaced every 2–3 wk, and serum samples of 200–300 µL should be collected 10–12 d after each boost.




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Understanding the Pandemic: New Virtual Programs Announced

The National Book Festival Presents series was created to provide a book festival experience to lovers of the event on a year-round basis. Because these programs can no longer be held at the Library, we are offering a virtual multipart series, with authors who have written books about widespread diseases and the worldwide response to them.




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For 100 Years, KitchenAid Has Been the Stand-Up Brand of Stand Mixers

Even celebrity chef Julia Child said that the sleek appliance made mixing 'marvelous'




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Jurisdictions move towards full implementation of standards for financial market infrastructures

CPMI Press release "Jurisdictions move towards full implementation of standards for financial market infrastructures", 8 April 2020.




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No pomp, under the circumstances: CBU holding online convocation

What would have been Cape Breton University's largest convocation to date is being replaced by an online offering this year because of COVID-19. Some graduating students say it just won't be the same as a traditional ceremony.



  • News/Canada/Nova Scotia

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8M substandard masks from Montreal supplier did not make it into health-care system, Trudeau says




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Distant notes |India Today Insight – India Today

Distant notes |India Today Insight  India Today



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