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Highly responsive and rapid hydrogen peroxide-triggered degradation of polycaprolactone nanoparticles

Biomater. Sci., 2020, 8,2394-2397
DOI: 10.1039/C9BM02019E, Communication
Peng-Hao Hsu, Carina Arboleda, Alexandra Stubelius, Ling-Wei Li, Jason Olejniczak, Adah Almutairi
Nanoparticles formulated from fast-degrading oxidation-responsive polycaprolactone are responsive to 50 μM of H2O2.
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Topography induced stiffness alteration of stem cells influences osteogenic differentiation

Biomater. Sci., 2020, 8,2638-2652
DOI: 10.1039/D0BM00264J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Liangliang Yang, Qi Gao, Lu Ge, Qihui Zhou, Eliza M. Warszawik, Reinier Bron, King Wai Chiu Lai, Patrick van Rijn
Topography-driven alterations to single cell stiffness rather than alterations in cell morphology, is the underlying driver for influencing cell biological processes, particularly stem cell differentiation.
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Advances in living cell-based anticancer therapeutics

Biomater. Sci., 2020, 8,2344-2365
DOI: 10.1039/D0BM00036A, Review Article
He Dong, Xiao Xu, Leikun Wang, Ran Mo
This review summarizes recent advances in the applications of living cells as drug carriers or active drugs for anticancer drug delivery and cancer therapy.
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Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications

Biomater. Sci., 2020, 8,2434-2446
DOI: 10.1039/D0BM00182A, Paper
Jann Harberts, Undine Haferkamp, Stefanie Haugg, Cornelius Fendler, Dennis Lam, Robert Zierold, Ole Pless, Robert H. Blick
Nanostructured substrates such as nanowire arrays form a powerful tool for building next-generation medical devices.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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Modulating neutrophil extracellular traps for wound healing

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00355G, Paper
Tejinder Kaur, Shweta Dumoga, Veena Koul, Neetu Singh
An alginate-GelMa scaffold for modulating neutrophil extracellular traps using a PAD4 inhibitor could be a novel therapeutic approach for wound healing.
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A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00474J, Paper
Qiwen Wang, Jie Shen, Enqi Mo, Haotian Zhang, Jianwei Wang, Xiurong Hu, Jun Zhou, Hongzhen Bai, Guping Tang
An H+-modified montmorillonite (H-MMT) was prepared using an acid modification method to obtain powerful absorption ability as a theranostic platform for both metabolic syndrome and gastric mucosa protection.
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Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00312C, Paper
Kunnumpurathu Jibin, Jayaram S. Prasad, Giridharan Saranya, Sachin J. Shenoy, Kaustabh K. Maiti, Ramapurath S. Jayasree
Gold–graphene nanohybrid for simultaneous dual-imaging guided triple therapy as a new paradigm in light-triggered cancer theranostics. The material demonstrates excellent therapeutic efficacy and treatment monitoring features.
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A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper
Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
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Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage

Toxicol. Res., 2019, 8,833-841
DOI: 10.1039/C9TX00080A, Paper
Qiaoyun Liu, Longsheng Wang, Hanwen Chen, Bo Huang, Jiawei Xu, Ying Li, Paul Héroux, Xinqiang Zhu, Yihua Wu, Dajing Xia
Prometryn induces oxidative stress-mediated DNA damage; Prometryn induces S phase of cell cycle arrest; Prometryn induces Bax-dependent apoptosis in BEAS-2B cells.
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Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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Characteristic synergistic cytotoxic effects toward cells in graphene oxide dressing with cadmium and copper ions

Toxicol. Res., 2019, 8,908-917
DOI: 10.1039/C9TX00146H, Paper
Yiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
Cadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.
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Synergistic antioxidant capacity of CsNPs and CurNPs against cytotoxicity, genotoxicity and pro-inflammatory mediators induced by hydroxyapatite nanoparticles in male rats

Toxicol. Res., 2019, 8,939-952
DOI: 10.1039/C9TX00221A, Paper
Israa F. Mosa, Mokhtar Youssef, Maher Kamel, Osama F. Mosa, Yasser Helmy
Due to their dynamic characteristics, hydroxyapatite nanoparticles (HAP-NPs) have been employed numerous times in nanomedicine and in tissue engineering, particularly as diagnostic and therapeutic agents.
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Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis

Toxicol. Res., 2019, 8,972-978
DOI: 10.1039/C9TX00142E, Paper
Open Access
Rashin Ghaffari, John H. Richburg
Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
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Application of the direct peptide reactivity assay (DPRA) to inorganic compounds: a case study of platinum species

Toxicol. Res., 2019, 8,802-814
DOI: 10.1039/C9TX00242A, Paper
Jocelyn D. C. Hemming, Mark Hosford, Martin M. Shafer
The in chemico Direct Peptide Reactivity Assay (DPRA) was developed as a non-animal, relatively high throughput, screening tool for skin sensitization potential.
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Franklin Templeton issues apology to Sebi for global chief's remarks

Stung by the comments made by the global chief, market regulator on Thursday issued a press release defending the new rules it introduced in October last year




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Export contraction in April could surpass March's steep 25-year decline

Major forex earning sectors cite lack of labour, funds and key supplies




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Adityanath seeks ways to boost tax revenue as UP misses April target by 90%

Chairing a review meeting here, Adityanath directed the revenue minister and other senior officials to look at additional sources of revenue and accelerate tax collection




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Miners want mandatory capex rule relaxed as workers stay away fearing Covid

None of the merchant mines in Odisha whose lease validity expired by March 31 has been able to restart. Though the successful bidders have got LoI, they awaiting formal vesting orders




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Release of graphene-related materials from epoxy-based composites: characterization, quantification and hazard assessment in vitro

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10245K, Paper
Open Access
Woranan Netkueakul, Daria Korejwo, Tobias Hammer, Savvina Chortarea, Patrick Rupper, Oliver Braun, Michel Calame, Barbara Rothen-Rutishauser, Tina Buerki-Thurnherr, Peter Wick, Jing Wang
We measured the cytotoxicity of pristine GRMs and the abraded particles from epoxy/GRM composites, which indicated low risks to consumers of such composites.
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Wrinkle-induced highly conductive channels in graphene on SiO2/Si substrate

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01406K, Paper
Ruisong Ma, Jiajun Ma, Jiahao Yan, Liangmei Wu, Wei Guo, Shuai Wang, Qing Huan, Lihong Bao, Sokrates T Pantelides, Hong-Jun Gao
Graphene wrinkle is a quasi-one-dimensional structure and can alter the intrinsic physical and chemical activity, modify the band structure and introduce transport anisotropy in graphene thin films. However, their quasi-one-dimensional...
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Plasma-assisted filling electron beam lithography for high throughput patterning of large area closed polygon nanostructures

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01032D, Paper
You Sin Tan, Hailong Liu, Qifeng Ruan, Hao Wang, Joel K. W. Yang
The PFEBL process allows enhancement of electron beam writing efficiency for patterning of closed polygon structures using a post-exposure plasma treatment.
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Correction: Anomalous polarization dependence of Raman scattering and crystallographic orientation of black phosphorus

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR90098B, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jungcheol Kim, Jae-Ung Lee, Jinhwan Lee, Hyo Ju Park, Zonghoon Lee, Changgu Lee, Hyeonsik Cheong
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Pristine Graphene Induces Innate Immune Training

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/C9NR09661B, Paper
Filipa Lebre, John B Boland, Pedro Gouveia, Aoife Gorman, Mimmi Lundahl, Fergal J O'Brien, Jonathan N Coleman, Ed Lavelle
Graphene-based materials are of increasing interest for their potential use in biomedical applications. However, there is a need to gain a deeper understanding of how graphene modulates biological responses before...
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Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy

Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper
Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
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Boosting the photocatalytic CO2 reduction of metal–organic frameworks by encapsulating carbon dots

Nanoscale, 2020, 12,9533-9540
DOI: 10.1039/D0NR01696A, Paper
Shumin Li, Kang Ji, Meng Zhang, Cangshuang He, Jin Wang, Zhengquan Li
Small carbon dots as cocatalysts were loaded in MOF particles for CO2 reduction and their location effect was explored.
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Strong plasmon–exciton coupling between lithographically defined single metal nanoparticles and monolayer WSe2

Nanoscale, 2020, 12,9708-9716
DOI: 10.1039/D0NR01056A, Paper
Xiaohong Yan, Hong Wei
Strong coupling between monolayer WSe2 and lithographically defined single gold nanobowties is realized for the first time, and smaller nanobowties lead to larger coupling strength.
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Facile synthesis of core–shell structured Si@graphene balls as a high-performance anode for lithium-ion batteries

Nanoscale, 2020, 12,9616-9627
DOI: 10.1039/D0NR01346C, Paper
Anif Jamaluddin, Bharath Umesh, Fuming Chen, Jeng-Kuei Chang, Ching-Yuan Su
Encapsulating silicon (Si) nanoparticles with graphene nanosheets in a microspherical structure is proposed to increase electrical conductivity and solve stability issues when using Si as an anode material in lithium-ion batteries (LIBs).
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A high-efficiency ammonia-responsive solar evaporator

Nanoscale, 2020, 12,9680-9687
DOI: 10.1039/D0NR00791A, Paper
Jingjing Xing, Jintao Tong, Ye Liu, Yutong Guo, Lanjian Zhuge, Dafeng Zhang, Ruomeng Duan, Bo Song, Yu Zhao, Bin Dong
We report a highly efficient solar evaporator based on the TiO2NP and PPyNP composite with ammonia responsiveness.
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Reply to the ‘Comment on “Hierarchically porous, ultra-strong reduced graphene oxide–cellulose nanocrystal sponges for exceptional adsorption of water contaminants”’ by J. Ma, Y. Xiong and F. Yu, Nanoscale, 2019, 11, DOI: 10.1039/C8NR08780F

Nanoscale, 2020, 12,9899-9901
DOI: 10.1039/D0NR01846E, Comment
Nariman Yousefi, Nathalie Tufenkji
We respond to the comments of Ma et al. and clarify the rationale behind our methodology and why it is suitable for our work.
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CVD growth of large-area InS atomic layers and device applications

Nanoscale, 2020, 12,9366-9374
DOI: 10.1039/D0NR01104E, Communication
Chien-Liang Tu, Kuang-I Lin, Jiang Pu, Tsai-Fu Chung, Chien-Nan Hsiao, An-Ci Huang, Jer-Ren Yang, Taishi Takenobu, Chang-Hsiao Chen
Indium sulfide (InS) atomic layers made by chemical vapor deposition (CVD) are synthesized onto a mica substrate, producing a highly crystalline, large-area, and atomically thin-film InS flakes.
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Plasmonic nanopapers: flexible, stable and sensitive multiplex PUF tags for unclonable anti-counterfeiting applications

Nanoscale, 2020, 12,9471-9480
DOI: 10.1039/D0NR01223H, Paper
Hongrui Cheng, Yongfeng Lu, Dongyan Zhu, Lorenzo Rosa, Fei Han, Mingguo Ma, Wenyue Su, Paul S. Francis, Yuanhui Zheng
Highly flexible and stable plasmonic nanopaper comprised of silver nanocubes and cellulose nanofibres was fabricated through a self-assembly-assisted vacuum filtration method.
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Ternary PtFeCo alloys on graphene with high electrocatalytic activities for methanol oxidation

Nanoscale, 2020, 12,9824-9832
DOI: 10.1039/D0NR00757A, Paper
Hongfei Wang, Kefu Zhang, Jun Qiu, Juan Wu, Jingwen Shao, Huijuan Wang, Yujuan Zhang, Jie Han, Yong Zhang, Lifeng Yan
Ternary PtFeCo alloys as alternatives to conventional Pt electrocatalysts are highly important in the field of the methanol oxidation reaction.
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Designing transition-metal-boride-based electrocatalysts for applications in electrochemical water splitting

Nanoscale, 2020, 12,9327-9351
DOI: 10.1039/D0NR01279C, Review Article
Yuanyuan Jiang, Yizhong Lu
Recent progresses made in transition metal boride (TMB)-based electrocatalysts for electrochemical water splitting are summarized.
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NiSe2-anchored N, S-doped graphene/Ni foam as a free-standing bifunctional electrocatalyst for efficient water splitting

Nanoscale, 2020, 12,9866-9872
DOI: 10.1039/D0NR00879F, Paper
Jinhao Zhou, Zegao Wang, Dongxu Yang, Fei Qi, Xin Hao, Wanli Zhang, Yuanfu Chen
A strategy to synthesize free-standing electrocatalysts coupling active nanostructured NiSe2 with conductive S, N-doped 3D graphene foam (3DSNG) is presented and the hybrid delivers superior performances for the HER, OER and overall water splitting.
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Nanosphere-shaped ammonio methacrylate copolymers: converting a pharmaceutical inactive ingredient to efficient therapeutics for experimental colitis

Nanoscale, 2020, 12,9590-9602
DOI: 10.1039/D0NR00465K, Paper
Brice Moulari, Maryam A. Shetab Boushehri, Jean-Paul Pais de Barros, Thilo Faber, Arnaud Béduneau, Laurent Lagrost, Yann Pellequer, Alf Lamprecht
Even in the absence of any drug load, nanosphere-shaped ammonio methacrylate copolymers can mitigate murine experimental colitis.
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High charge carrier mobility in solution processed one-dimensional lead halide perovskite single crystals and their application as photodetectors

Nanoscale, 2020, 12,9688-9695
DOI: 10.1039/D0NR01495H, Paper
Tianjun Liu, Weidong Tang, Sally Luong, Oliver Fenwick
Large space-charge limited mobility and a fast optical response is reported in low dimensional halide perovskite crystals. A transition between hopping transport and band-like transport is observed at 200 K.
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Quantitative encapsulation and retention of 227Th and decay daughters in core–shell lanthanum phosphate nanoparticles

Nanoscale, 2020, 12,9744-9755
DOI: 10.1039/D0NR01172J, Paper
M. Toro-González, A. N. Dame, C. M. Foster, L. J. Millet, J. D. Woodward, J. V. Rojas, S. Mirzadeh, S. M. Davern
La(227Th)PO4 core +2 shells nanoparticles retained >99.75% of activity from 227Th and decay daughters (223Ra, 211Pb) for targeted alpha therapy.
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Tuning the electronic structure of transition metals embedded in nitrogen-doped graphene for electrocatalytic nitrogen reduction: a first-principles study

Nanoscale, 2020, 12,9696-9707
DOI: 10.1039/D0NR00072H, Paper
Xiaonan Zheng, Yuan Yao, Ya Wang, Yang Liu
The Fe/Mn–N–C catalyst is a promising candidate for the NRR as it shows significantly improved NRR catalytic activity and strong selectivity against the HER.
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Actuated plasmonic nanohole arrays for sensing and optical spectroscopy applications

Nanoscale, 2020, 12,9756-9768
DOI: 10.1039/D0NR00761G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Daria Kotlarek, Stefan Fossati, Priyamvada Venugopalan, Nestor Gisbert Quilis, Jiří Slabý, Jiří Homola, Médéric Lequeux, Frédéric Amiard, Marc Lamy de la Chapelle, Ulrich Jonas, Jakub Dostálek
We report a new approach to rapidly actuate the plasmonic characteristics of thin gold films perforated with nanohole arrays by thermo-responsive hydrogel and demonstrate its utilization to sensing with flow-through format and SPR/SERS readout.
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MnV2O6/Graphene Nanocomposite as an Efficient Electrocatalyst for the Oxygen Evolution Reaction

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02325F, Communication
Kyeong-Ho Kim, Yun-Hyuk Choi, Seong-Hyeon Hong
MnV2O6/graphene nanocomposite was fabricated through hydrothermal synthesis and high energy mechanical milling as an electrocatalyst for oxygen evolution reaction (OER). MnV2O6/graphene (20 wt%) nanocomposite deposited on carbon fiber paper (CFP)...
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Exploring the Limits of Sensitivity for Strain Gauges of Graphene and Hexagonal Boron Nitride Decorated with Metallic Nanoislands

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02270E, Paper
Julian Ramirez, Armando Urbina, Andrew T Kleinschmidt, Mickey Finn, Samuel J. Edmunds, Guillermo L. Esparza, Darren J Lipomi
The purpose of this work is to clarify the mechanism of piezoresistance in a class of ultra-sensitive strain gauges based on metallic films on 2D substrates (“2D/M” films). The metals...
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Direct carbonization of organic solvent toward graphene quantum dots

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01903H, Communication
Hongji Liu, Xiaotong Lv, Changwei Li, Yong Qian, Xingyu Wang, Lin Hu, Yu-Cai Wang, Wenchu Lin, Hui Wang
The bottom-up synthesis of graphene quantum dots (GQDs) using solvothermal method has attracted considerable attention because of their fewer defects and controllable size/ morphology. However, the influence of organic solvent...
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Near-infrared nanosecond-pulsed laser-activated high efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01792B, Paper
Tuhin Subhra Santra, Srabani Kar, Chih-Wei Chen, Jayant Borana, Te-Chang Chen, Ming-Chang Lee, Fan-Gang Tseng
Here, efficient intracellular delivery of molecules with high cell viability is reported using nanosecond-pulsed laser-activated plasmonic photoporation mediated by high-aspect-ratio nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles (nm-AuPNPs) at near-infrared wavelength. Upon...
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Let me draw you a map: knowledge management from "two completely different streams of thought"

Let me draw you a map: knowledge management from "two completely different streams of thought" HeavyHead, Danielle; Greenshields, Mary This paper represents the results of a conversation between Adrienne Heavy Head, the creator and manager of the Blackfoot Digital Library (BDL), at the University of Lethbridge in Alberta, Canada, and Mary Greenshields, a new librarian in Alberta. The aim of the conversation was for Mary, a settler living in traditional Blackfoot Territory, to learn about the creation and maintenance of the BDL and to gain insight into the organization, access, and classification of information within the library as a real-life example of some of the Protocols suggested by the Canadian Federation of Library Associations. Adrienne and Mary hope that this conversation will help librarians to better understand knowledge management from a Blackfoot perspective and might inspire librarians to start and continue such conversations with the Indigenous peoples upon whose lands their libraries rest. Open access article. Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0) applies.




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To appreciate my role as a scientist, I had to step outside academia

This Ph.D. student learned that science policy work satisfies her desire to make an impact




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Napoleon's aide settle 'God's own resting place'




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Capital's oldest public building is a church




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Real royalty once graced Florida's capital




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Florida capitol old as the state itself