Plazomicin was tested against 697 recently acquired carbapenem-resistant Klebsiella pneumoniae isolates from the Great Lakes region of the United States. Plazomicin MIC₅₀ and MIC₉₀ values were 0.25 and 1 mg/liter, respectively; 680 isolates (97.6%) were susceptible (MICs of ≤2 mg/liter), 9 (1.3%) intermediate (MICs of 4 mg/liter), and 8 (1.1%) resistant (MICs of >32 mg/liter). Resistance was associated with rmtF-, rmtB-, or armA-encoded 16S rRNA methyltransferases in all except 1 isolate.

People with type 1 diabetes may receive a significant portion of their care from primary care providers (PCPs). To understand the involvement of PCPs in delivering type 1 diabetes care, we performed surveys in California and Florida, two of the most populous and diverse states in the United States. PCPs fill insulin prescriptions but report low confidence in providing type 1 diabetes care and difficulty accessing specialty referrals to endocrinologists.

BACKGROUND AND PURPOSE:

Not all tandem occlusions diagnosed on traditional vascular imaging modalities, such as MRA, represent actual complete ICA occlusion. This study aimed to explore the utility of high-resolution vessel wall imaging in identifying true ICA tandem occlusions and screening patients for their suitability for endovascular recanalization.

BACKGROUND AND PURPOSE:

After endovascular coiling of intracranial aneurysms, round dark parenchymal lesions believed to be particulate metal are sometimes encountered in MR imaging studies of the brain. We used SWI to assess the frequency of such occurrences, in addition to exploring likely causes and clinical implications.

Self-made millionaire David Bach says not buying a home is the single biggest mistake millennials (who were born between 1980 and 2000) are making.

Nguyen Tran Nam, former Deputy Minister of Construction, also President of the Vietnam Real Estate Association (VNREA) says in comparison to buying, renting a home is a better solution for young Vietnamese.

पंजाब पुलिस ने गुरुवार को अमृतसर से आतंकियों के दो मददगारों को गिरफ्तार किया है।

It’s quite the spectacle, but the light show is leading people to be less than cautious about social distancing.

People overreact to layoffs. Candy Box consumes another person’s life. Square Enix decides the best thing for its future is to make an HD version...

Jingle bells, tarutaru smell, people played FF 14. Alex played more Xenoblade and Alice played Warframe. Happy Holidays!

"I just couldn't be more proud of you and the prospect of your presidency," Newsom told Biden Friday during a campaign event.

A species of plant that grew about 400 million years ago (Early Devonian period) produced a spectrum of spore sizes, which is an essential innovation necessary for all advanced plant reproductive strategies, including seeds and flowers. The Devonian period is one of the most important time periods for the evolution of land plants. It witnessed [...]

While the present-day Martian surface is generally dry and cold, its sedimentary rocks contain compelling evidence for the former presence of liquid water. According to a new analysis of orbital images of 3.7-billion-year-old sedimentary layers at Izola mensa, an outcrop in the northwestern rim of the Hellas impact crater on Mars, deep rivers were active [...]

Mouse neurons trapped inside cages grow long appendages to connect to each other. Trapping the cells allows us to precisely control their growth

Oscar-winning Iranian director Asghar Farhadi said Sunday he will not attend the Academy Awards on Feb. 26, “even if exceptions were to be made for my trip,” as protests over President Donald Trump's immigration ban spread to Hollywood's biggest global stage.

Sania Mirza took to social media to post a picture with her son Izhaan.

California on Friday became the first state to commit to sending mail-in ballots to all registered voters for the November election as a result of the coronavirus pandemic to safeguard voter access and public safety.

Thousands of cyclists took over streets in the centre of the Slovenian capital Ljubljana on Friday evening to protest against the government of Prime Minister Janez Jansa and the restrictions it has imposed to fight the coronavirus.

Spain's daily death toll from the coronavirus fell to its second lowest since mid-March on Saturday, as half the country prepared to move to the next phase of an exit from one of Europe's strictest lockdowns.

County officials in northern California county are threatening to sue Gov. Gavin Newsom if he doesn't ease his requirements to begin letting municipalities lift lockdown measures amid the coronavirus crisis that has fractured the global economy.

California Gov. Gavin Newsom on Friday signed an executive order that will send every registered voter in the state a mail-in ballot for November’s presidential election -- immediately raising concerns from Republicans that it would lead to fraud and abuse.

The attempts seem to be experiments that were quickly abandoned, and none of those identified received substantial engagement.

Pennsylvania Gov. Tom Wolf has a brewing rebellion on his hands as counties set out to defy his plans.

California Gov. Gavin Newsom on Friday signed an executive order that will send every registered voter in the state a mail-in ballot for November’s presidential election -- immediately raising concerns from Republicans that it would lead to fraud and abuse.

Crowds are coming to see the light show as beaches begin to reopen after an almost month-long closure due to coronavirus

Mother nature has provided a radical gift to nighttime beach-goers in southern California, in the form of bioluminescent waves that crash and froth with an otherworldly light.

Related: California surf shimmers with bioluminescence – in pictures

The newly launched #SmithsonianEdu campaign highlights 1.7 million online tools geared specifically toward students and teachers

As a biological anthropologist focused on health, diseases are part of Sabrina Sholts' specialty

The two-day virtual event will bring scientists and many other experts to highlight success stories in conservation

Meet the hugely influential polymath, who foretold of climate change and inspired artists, writers and even the founder of the Smithsonian

Tesla Inc has not been allowed to resume operations at its California vehicle factory as local lockdown measures to curb the spread of the coronavirus remain in effect, a county health official said on Friday.

Tesla Inc "must not reopen" its vehicle factory in the San Francisco Bay area as local lockdown measures to curb the spread of the coronavirus remain in effect, the local county health department said on Friday.

Tesla Inc "must not reopen" its vehicle factory in the San Francisco Bay area as local lockdown measures to curb the spread of the coronavirus remain in effect, the local county health department said on Friday.

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One dog owner has found out the hard way that giving her Pomeranian a haircut at home during the coronavirus lockdown isn't an easy job.

Officials in San Clemente draw line in the sand at local park after weeks of rule-breaking by unruly skateboarders

Donald Trump has instructed the US Navy to shoot down and destroy Iranian gunboats "if they harass our ships at sea".

Nail-biting video captures the moment police in the US flip suspect's car was flipped as part of a manoeuvre to end a pursuit.

Police have been forced to close a California beach after thousands of people flouted the lockdown to bask in a heatwave.

Joggers, cyclists and surfers across Spain have emerged from their homes as adults were allowed out for exercise for the first time in seven weeks.

Hundreds of protestors have swarmed the streets in Huntington Beach in California to demand an end to coronavirus lockdown rules.

California's governor has announced that the six-week lockdown of America's most populous state will be relaxed within days as the daily coronavirus death toll across the United States fell to its lowest level in a month.

Grimes and her boyfriend Elon Musk want to call their newborn son X Æ A-12 Musk, but California law might prevent it.