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1.6bn informal workers hit by lockdowns: ILO

ISLAMABAD: As many as 1.6 billion of the world’s 2bn informal economy workers are affected by Covid-19 lockdown and containment measures, a new briefing paper issued by the International Labour Organi­sation (ILO) said.

Most are working in the hardest-hit sectors or in small units more vulnerable to shocks including workers in accommodation and food services, manufacturing, wholesale and retail, and the more than 500 million farmers producing for the urban market, the report says. Women are particularly affected in high-risk sectors, it adds.

The Covid-19 lockdown and containment measures threaten to increase relative poverty levels among the world’s informal economy workers by as much as 56 percentage points in low-income countries.

In high-income countries, relative poverty levels among informal workers is estimated to increase by 52 percentage points, while in upper middle-income countries the increase is estimated to be 21 percentage points.

In addition, with these workers needing to work to feed their families, Covid-19 containment measures in many countries cannot be implemented successfully. This is endangering governments’ efforts to protect the population and fight the pandemic. It may become a source of social tension in countries with large informal economies, the report says.

More than 75 per cent of total informal employment takes place in businesses of fewer than ten workers, including 45pc of independent workers without employees.

With most informal workers having no other means of support, they face an almost unsolvable dilemma: to die from hunger or from the virus, the briefing says. This has been exacerbated by disruptions in food supplies, which has particularly affected those in the informal economy.

For the world’s 67 million domestic workers, 75pc of whom are informal workers, unemployment has become as threatening as the virus itself. Many have not been able to work, whether at the request of their employers or in compliance with lockdowns. Those who do continue to go to work face a high risk of contagion, caring for families in private households. For the 11 million migrant domestic workers the situation is even worse.

The countries with the largest informal economies, where full lockdowns have been adopted, are suffering the most from the consequences of the pandemic. Informal economy workers significantly impacted by lockdown vary from 89pc in Latin America and the Arab states to 83pc in Africa, 73pc in Asia and the Pacific, and 64pc in Europe and Central Asia.

Countries need to follow a multi-track strategy that combines several lines of actions relating to both the health and economic impacts of the pandemic, the ILO said.

Among its recommendations, the report highlights the need for policies that reduce the exposure of informal workers to the virus; ensure that those infected have access to health care; provide income and food support to individuals and their families; and prevent damage to the economic fabric of countries.

Published in Dawn, May 9th, 2020




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3353-VIE: The Second Greater Mekong Subregion (GMS) Corridor Towns Development Project [Package SP2]




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Baby Boom After Pandemic Lockdowns? Maybe Not

Title: Baby Boom After Pandemic Lockdowns? Maybe Not
Category: Health News
Created: 5/8/2020 12:00:00 AM
Last Editorial Review: 5/8/2020 12:00:00 AM




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Erratum for Townsend et al., "A Master Regulator of Bacteroides thetaiotaomicron Gut Colonization Controls Carbohydrate Utilization and an Alternative Protein Synthesis Factor"




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X-Linked RNA-Binding Motif Protein Modulates HIV-1 Infection of CD4+ T Cells by Maintaining the Trimethylation of Histone H3 Lysine 9 at the Downstream Region of the 5' Long Terminal Repeat of HIV Proviral DNA

ABSTRACT

Reversible repression of HIV-1 5' long terminal repeat (5'-LTR)-mediated transcription represents the main mechanism for HIV-1 to maintain latency. Identification of host factors that modulate LTR activity and viral latency may help develop new antiretroviral therapies. The heterogeneous nuclear ribonucleoproteins (hnRNPs) are known to regulate gene expression and possess multiple physiological functions. hnRNP family members have recently been identified as the sensors for viral nucleic acids to induce antiviral responses, highlighting the crucial roles of hnRNPs in regulating viral infection. A member of the hnRNP family, X-linked RNA-binding motif protein (RBMX), has been identified in this study as a novel HIV-1 restriction factor that modulates HIV-1 5'-LTR-driven transcription of viral genome in CD4+ T cells. Mechanistically, RBMX binds to HIV-1 proviral DNA at the LTR downstream region and maintains the repressive trimethylation of histone H3 lysine 9 (H3K9me3), leading to a blockage of the recruitment of the positive transcription factor phosphorylated RNA polymerase II (RNA pol II) and consequential impediment of transcription elongation. This RBMX-mediated modulation of HIV-1 transcription maintains viral latency by inhibiting viral reactivation from an integrated proviral DNA. Our findings provide a new understanding of how host factors modulate HIV-1 infection and latency and suggest a potential new target for the development of HIV-1 therapies.

IMPORTANCE HIV-1 latency featuring silence of transcription from HIV-1 proviral DNA represents a major obstacle for HIV-1 eradication. Reversible repression of HIV-1 5'-LTR-mediated transcription represents the main mechanism for HIV-1 to maintain latency. The 5'-LTR-driven HIV gene transcription can be modulated by multiple host factors and mechanisms. The hnRNPs are known to regulate gene expression. A member of the hnRNP family, RBMX, has been identified in this study as a novel HIV-1 restriction factor that modulates HIV-1 5'-LTR-driven transcription of viral genome in CD4+ T cells and maintains viral latency. These findings provide a new understanding of how host factors modulate HIV-1 infection and latency and suggest a potential new target for the development of HIV-1 therapies.




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Continue reading...




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Malls across America resemble ghost towns as they reopen...


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(Third column, 2nd story, link)





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Motsi Mabuse: ‘People didn't expect black people in ballgowns’

Strictly’s newest judge learned to stick up for herself in apartheid-era South Africa. She talks racism, the ‘rift’ with her sister Oti – and learning to dance amid knife fights

Motsi Mabuse is remembering the rough dance halls of apartheid-era South Africa and the shocking sights she would see as she took her first tentative steps across their floors. “When we had competitions,” she says, “we didn’t have security and people would be drunk and starting fights. We were just kids and we’d watch people with knives running through while we were in the middle of a routine. Compared to that, Strictly isn’t so difficult.”

Mabuse, the newest judge on Strictly Come Dancing, first fell for the glitterball world at the age of nine after watching couples waltz, swing and cha-cha-cha while on holiday in Durban. “What I love about my parents is that they didn’t say: ‘Oh, you can’t do that.’ They found a way. But we had a lot of backlash, being the only black kids. People would laugh at us and call us names. We were bullied, but we just kept on coming back – and then we beat them.”

Continue reading...




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Bow down to the politician who's the Queen of verbal smackdowns

Australia's political landscape has long been tumultuous and rough around the edges. But amoung the rough, there is a diamond. Enter ex-prime minister, sharp shooter and straight talker, Paul Keating. He's sassy AF.

Keating made headlines again Wednesday by implying the country's foreign policy was suffering because governmental powers are too concerned with appeasing the U.S. 

It's just the latest public comment in the long line of brutal honesty and cynical realism that is Paul Keating's autobiography. Need hard evidence? Watch and learn children. The shade. Read more...

More about Australian Politics, Australia, Paul Keating, World, and Australia




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Indian pharma & machinery sector sees Smart Factory model to mitigate future challenges of COVID─19 like lockdowns




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Federal Judge Hands Downs Sentences in Holy Land Foundation Case

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