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Illuminating cisplatin-induced ferroptosis in non-small-cell lung cancer with biothiol-activatable fluorescent/photoacoustic bimodal probes

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01656D, Paper
Li Xu, Hongwen Liu, Yi Kong, Lingyun Li, Jia Li, Kang Li, Shuzhi Liang, Bolin Chen
Using activatable NIR fluorescent/PA bimodal probes, we successfully monitored real-time biothiol changes during ferroptosis in NSCLC cells and tumors, revealing enhanced ferroptosis with the combined use of erastin and cisplatin.
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Bigg Boss 16: Guess Who Is NOMINATED?

Day 3 inside the Bigg Boss house has the contestants at loggerheads even as they take part in the first nomination task.




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Bigg Boss 16: Is Soundarya Dominating?

With so many equations changing everyday, the Bigg Boss game is finally beginning to seem exciting.




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Bigg Boss 16: Will Vikas Get Eliminated? PREDICT!

Will he be the latest contestant to leave the show?




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97 national awardee teachers for 2020 and 2021 write to President, PM to honour them in physical ceremony on September 5

All these teachers had received the award in a virtual event due to the COVID-19 restrictions. Of them, 47 teachers had received the award in 2020 and the rest in 2021




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The Hindu EducationPlus International Education Fair in Bengaluru




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The Hindu International Education Fair opens with huge response

Hundreds of students and parents visited the stalls and interacted with colleges, universities, consulates, and agencies from across the globe, and got information about overseas education




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The illuminated and a new way of seeing

Anindita Ghose’s debut novel is a visceral account of loss and emerging anew from it




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Kalidasa, the poet of the natural world

As it rains, it is natural to turn to the epic writer whose verses bring home the monsoons and the plants in which the season become visible




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Golden Globes 2018: Shape Of Water, Dunkirk, Big Little Lies lead nominations

Other nominations include Dunkirk, The Post and I, Tonya.




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Shape Of Water leads Oscars nominations

Dunkirk may have been missed at the year's earlier awards shows, but thanks god, Chris Nolan's classic gets enough play at the Oscar noms.




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Roma, The Favourite lead 2019's Oscar nominations!

Which films are *you* rooting for?




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BAFTA Nominations: RRR Out, All That Breathes In

This comes as a rare miss for RRR, which bagged a Golden Globe for Best Original Song for the song Naatu Naatu and Critics Choice Awards for Best Foreign Language film and Best Song.




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Barbie, Oppenheimer Lead Golden Globe Nominations

The nominations for the 81st annual Golden Globes are out, and Barbie and Succession lead the list.




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'This Is For Every Native Kid Who Has A Dream'

Lily Gladstone picked up the Best Female Actor- Motion Picture award at the Golden Globes for her performance in Martin Scorsese's Killers of The Flower Moon.




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Oscar Nominations: A Quick Glance

The nominations for the 96th annual Academy Awards have been announced.




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Rapid quantification of disaccharide isomers by derivatization in combination with ion mobility spectrometry in beer and milk

Analyst, 2024, 149,5298-5305
DOI: 10.1039/D4AN00995A, Paper
Keqi Ye, Jiacheng Ye, Yinghua Yan, Chuan-Fan Ding
This work introduces rapid quantification of disaccharide isomers by derivatization in combination with ion mobility spectrometry in beer and milk.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Imaging specific proteins in living cells with small unnatural amino acid attached Raman reporters

Analyst, 2024, 149,5476-5481
DOI: 10.1039/D4AN00758A, Paper
Erli Cai, Yage Chen, Jing Zhang, Haozheng Li, Yiran Li, Shuai Yan, Zhiyong He, Quan Yuan, Ping Wang
For living HeLa cells, we report a small and minimally-invasive Raman reporter (about 2 aa and <1 kDa), which can be site-specifically introduced into proteins by genetic codon expansion combined with tetrazine ligation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Designing a novel paper-based microfluidic disc for rapid and simultaneous determination of multiple nutrient salts in water

Analyst, 2024, 149,5563-5571
DOI: 10.1039/D4AN01127A, Paper
Zhentao Sun, Youquan Zhao, Yameng Liu, Chen Chen, Hao Chen
A paper-based microfluidic disc is used for the rapid determination of various nutrients in water.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Structural determination of fructooligosaccharides and raffinose family oligosaccharides using logically derived sequence tandem mass spectrometry

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00872C, Paper
Chia Yen Liew, Wun-Long Li, Chi-Kung Ni
Logical procedures for structural determination of fructooligosaccharides and raffinose family oligosaccharides.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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A bank from ‘Karnata’



  • A J Vinayak

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Behind the glow: unveiling the nature of NanoLuc reactants and products

Phys. Chem. Chem. Phys., 2024, 26,27447-27458
DOI: 10.1039/D4CP02551B, Paper
Alessandro Bonardi, Michele Turelli, Giorgio Moro, Claudio Greco, Ugo Cosentino, Carlo Adamo
Among all the possible candidates involved in the NanoLuc bioluminiescnce, this computational analysis identifies the enol tautomer of furimazine as a probable reactive species and the zwitterionic forms of furimamide as the luminescent product.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hydrogen bond network structures of protonated 2,2,2-trifluoroethanol/ethanol mixed clusters probed by infrared spectroscopy combined with a deep-learning structure sampling approach: the origin of the linear type network preference in protonated fluoroal

Phys. Chem. Chem. Phys., 2024, 26,27751-27762
DOI: 10.1039/D4CP03534H, Paper
Po-Jen Hsu, Atsuya Mizuide, Jer-Lai Kuo, Asuka Fujii
Infrared spectroscopy combined with a deep-learning structure sampling approach reveals the origin of the unusual structure preference in protonated fluorinated alcohol clusters.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A combination of experimental and theoretical methods in evaluating triazole derivatives' mild steel corrosion inhibition ability in an acidic solution

Phys. Chem. Chem. Phys., 2024, Advance Article
DOI: 10.1039/D4CP03537B, Paper
Ngo Hong Cat Van, Nguyen Quang Trung, Pham Dinh Tu Tai, Pham Cam Nam, Dinh Quy Huong
The introduction of many nitrogen heteroatoms into inhibitor molecules improves corrosion inhibition efficiency.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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A Comprehensive Guide for Accurate Conformational Energies of Microsolvated Li+ Clusters with Organic Carbonates

Phys. Chem. Chem. Phys., 2024, Accepted Manuscript
DOI: 10.1039/D4CP03487B, Paper
Arseniy A. Otlyotov, Andrey Moshchenkov, Timofey P. Rozov, Anna A. Tuma, Alexander S. Ryzhako, Yury Minenkov
Organic carbonates and their mixtures are frequently used in electrolyte solutions in lithium-ion batteries. Rationalization and tuning of the related Li+ solvation processes are rooted in the proper identification of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Innovative, combinatorial and high-throughput approaches to degrader synthesis

Chem. Soc. Rev., 2024, Advance Article
DOI: 10.1039/D3CS01127E, Tutorial Review
Rebecca Stevens, James D. F. Thompson, Julie C. L. Fournier, Glenn A. Burley, David J. Battersby, Afjal H. Miah
In this review we highlight how the synthesis of degraders has evolved in recent years, in particular the application of high-throughput chemistry and screening approaches such as D2B and DEL technologies to expedite discovery timelines.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Construction of olefinic coordination polymer single crystal platforms: precise organic synthesis, in situ exploration of reaction mechanisms and beyond

Chem. Soc. Rev., 2024, Advance Article
DOI: 10.1039/D3CS01050C, Review Article
Qiaoqiao Zhang, Yong Wang, Pierre Braunstein, Jian-Ping Lang
Olefinic coordination polymers were used as universal single crystal platforms for precise organic synthesis, in situ mechanism exploration and photochemical applications.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Safety concerns dominate chaotic opening day of Chennai night street race

The opening day of the weekend turned out to be a damp squib for the fans as the organisers couldn’t get the circuit ready in time for the action to start




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A humdinger looms in the three-day Indian National Motorcycle Racing Championship

The contenders across all categories are closely bunched as the fourth round of the INMRC gets under way on September 6




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Indian National Motorcycle Racing Championship | Chiranth Vishwanath secures two pole positions




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At the brand new Madras International Karting Arena, drive on the track that Mika Hakkinen, Narain Karthikeyan, and Karun Chandhok raced on

At the brand new Madras International Karting Arena, drive on the track that Mika Hakkinen, Narain Karthikeyan, and Karun Chandhok raced on The 1.2 kilometre track is India’s first karting circuit built to FIA-CIK (Commission Internationale de Karting) specifications



  • Life &amp; Style

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National Motorcycle Racing Championship set for grand climax at MIC

Over 100 entrants, representing 19 teams, will vie for top honours across 19 races at MRF MMSC FMSCI Indian National Motorcycle Racing Championship in Chennai on October 4




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Sarthak Chavan clinches maiden National crown




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Watch: Remembering Dhyan Chand | National Sports Day

As we celebrate National Sports Day, we honour Major Dhyan Chand’s legacy




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Karnataka gets the better of NCOE; Railways beats Maharashtra; Photo: Velankanni Raj

NCOE came to the tournament with a reputation to defend, having won the Lakshmi Ammal memorial tournament in Kovilpatti in June. It hasn’t done well so far, losing two of its three ties




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India eyes Paris revenge against Germany in Test series as international hockey returns to Delhi

For the last 10 years, the capital's Major Dhyan Chand National Stadium, once considered the spiritual home of the game, has not hosted any international match.




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Karnataka defeats Chandigarh, makes the last-eight stage




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Chennai Corporation Schools register 88.86% pass in Plus Two examination

A total of 5,899 students of 32 Corporation schools appeared for the examination. As many as 2,129 boys and 2,995 girls cleared it. The pass percentage among boys was 81.07 while among the girls it was 91.5.




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Hello fungi : a little guide to nature / Nina Chakrabarti

Chakrabarti, Nina, author, illustrator




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Digital detox for hallucinating chatbots and other AI fails

Bengaluru start-up’s automated platform detects and fixes machine learning gone wrong




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The unfortunate truth about ‘pedigree’ and the founder ecosystem

How old school ties do matter in the Indian startup system, and why that’s a problem




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Visible light-activated polyphenol–Al3+ coordination for ambient and quantitative xylose-to-furfural conversion

Chem. Commun., 2024, Advance Article
DOI: 10.1039/D4CC04899G, Communication
Jinshu Huang, Qizhi Luo, Tengyu Liu, Song Yang, Hu Li
Visible light-enhanced coordination of polyphenol–Al3+ is uncovered to switch Lewis/Brønsted acid sites for room-temperature cascade upgrading of xylose to furfural in ultrahigh yields.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Fabrication of gelatin hydrogels using pre-coordinated lanthanide complexes via imine crosslinking

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC03886J, Communication
Chen-Cheng Yu, Yu Yun Hsu, Yu-Chia Su, Yi-Chen Yang, Tzu-Ying Wang, Yi-Cheun Yeh
Precoordinated lanthanide-containing complexes are used to crosslink polyethyleneimine-modified gelatin to form gelatin hydrogel through imine bond formation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Fluorination of antimonene hexagons

Chem. Commun., 2024, 60,13336-13339
DOI: 10.1039/D4CC03423F, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Michael Fickert, Rebeca Martinez-Haya, Diego López-Alcalá, Frank Hauke, José J. Baldoví, Andreas Hirsch, Gonzalo Abellán
Fluorination of two-dimensional antimonene hexagons synthesized through colloidal synthesis has been reached using CF4 plasma through a reactive ion etching process.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Sulfonated hierarchical ZSM-5 zeolite monoliths as solid acid catalyst for esterification of oleic acid

Chem. Commun., 2024, 60,13356-13359
DOI: 10.1039/D4CC05044D, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Binhang Zhao, Pan Yang, Nan Zhang, Donald R. Inns, Elena F. Kozhevnikova, Alexandros P. Katsoulidis, Ivan V. Kozhevnikov, Alexander Steiner, Haifei Zhang
Sulfonated hierarchical H-ZSM-5 monoliths were synthesized via ice-templating as solid acid catalysts for biodiesel production.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pivotal role of starch in restoring the photocatalytic performance of chitosan films for eliminating water pollutants

Chem. Commun., 2024, 60,13364-13367
DOI: 10.1039/D4CC04759A, Communication
Aman Chauhan, Archana Negi, Kirti, Moondeep Chauhan, Ajeet Kaushik, Ganga Ram Chaudhary
The enhanced adsorption properties of chitosan films after starch impregnation combined with the excellent charge-transfer traits of the CdS@CuS catalyst restore the reduced photocatalytic activity towards ciprofloxacin degradation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tuneable Sulfonated Hypercrosslinked Polymers for Selective Esterification: Insights into Performance and Stability

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC05208K, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Paul Schweng, Dorian Guerin-Faucheur, Freddy Kleitz, Robert Thomas Woodward
We report sulfonated hypercrosslinked polymers (SHCPs) as heterogeneous catalysts for the selective esterification of hexanoic acid with benzyl alcohol. The SHCPs demonstrate tuneable catalytic activity and selectivity, outperforming conventional acid...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Iron-catalysed intramolecular C(sp3)–H amination of alkyl azides

Chem. Commun., 2024, Advance Article
DOI: 10.1039/D4CC04169K, Feature Article
Open Access
Kai Wu, Chi-Ming Che
This review summarizes recent major advances in iron-catalysed C–H aminations of alkyl azides through iron–alkylnitrene/alkylimido intermediates to access various N-heterocycles.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Positional effects of electron-donating and withdrawing groups on the photophysical properties of single benzene fluorophores

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC04451G, Communication
Dopil Kim, Jun Yeong Kim, Haein Kim, Eunjin Jeong, Minhyuk Lee, Dongwook Kim, JunWoo Kim, Myung Hwan Park, Min Kim
We investigated how the positional arrangement of electron-donating (amino) and electron-withdrawing (ester) groups in single benzene-based fluorophores influences their emission properties. By synthesizing 26 regioisomeric fluorophores, we achieved wavelength modulation...
The content of this RSS Feed (c) The Royal Society of Chemistry