The present invention relates to a compound of formula A, wherein R is alkyl. Compound A may be used as an intermediate in the preparation of O-desmethyl venlafaxine or a salt thereof, and the present invention provides such a preparation, as well as a process for preparing the compound of formula A.

A process has been developed for preparing 2-methoxymethyl-1,4-benzenediamine (IV-a), other compounds of formula (IV), and the salts thereof, all of which may be used as primary intermediates in compositions for dyeing keratin fibers.

A branched hetero polyfunctional polyoxyalkylene compound represented by the following formula (1): wherein Z represents a hydroxyl group-removed residue of pentaerythritol or dipentaerythritol, OA1 and OA2 represent an oxyalkylene group having 2 to 4 carbon atoms, L1, L2 and L3 represent an alkylene group or an alkylene group that contains an ester bond, a urethane bond, an amide bond, an ether bond, a carbonate bond, a secondary amino group or a urea bond, X and Y are different from each other and represent a functional group capable of a chemical reaction; m and n are an average number of moles of the oxyalkylene group added, m represents 5 to 1,000, n represents 0 to 1,000, and p, q and r represent 0 or 1; and s1 is an integer of 2 or more and s1+s2=4 or 6.

Systems and methods for recommending media content items are provided. In some implementations, a method includes, identifying a first set of media items selected by a first plurality of users; causing a second set of media items to be displayed to a second user not included in the first plurality of users in accordance with the first set of media items. The first set of media items and the second set of media items are associated with a same media item category. In some implementations, the method optionally includes, identifying the second set of media items without regard to media content item selection history associated with the second user. In some implementations, the first and second sets of media items are news items.

Bioassays for detecting the ability of one sample of a food substance, nutritional supplement, therapeutic agent and/or disease preventive agent relative to that of a second sample of such a substance, supplement and/or agent to inhibit, upregulate or otherwise modulate translation initiation, and thereby demonstrate a disease curative and/or preventive effect in a human and/or animal that consumes a such substance, supplement and/or agent or to whom a such substance, supplement and/or agent is administered are provided.

The present invention provides: an uracil derivative represented by general formula (I) or a physiologically acceptable salt thereof (in the formula, R1 represents a hydrogen atom, a C1-10 alkyl group, a C2-6 alkene group or a 3- to 6-membered saturated or 4- to 6-membered unsaturated aliphatic ring group which may contain 1 to 2 hetero atoms independently selected from the group consisting of N, O and S; R2 represents a hydrogen atom, a halogen atom, a cyano group, —NRcRd, —N═CHN(CH3)2, or an C1-3 alkyl group; Ar1 and Ar2 independently represent a 5- to 6-membered aromatic ring group which may contain 1 to 3 hetero atoms independently selected from the group consisting of N, O and S; and L represents a 6-membered aromatic ring group which may contain 1 to 4 nitrogen atoms, a pyrazole group, a triazole group, or an imidazole group); and a therapeutic agent or prophylactic agent for various inflammatory diseases associated with elastase, comprises the compound or the like as an active ingredient.

The present invention provides a compound useful as an agent for the prevention or treatment of a sex hormone-dependent disease or the like. That is, the present invention provides a fused heterocyclic derivative represented by the following general formula (I), a pharmaceutical composition containing the same, a medicinal use thereof and the like. In the formula (I), ring A represents 5-membered cyclic unsaturated hydrocarbon or 5-membered heteroaryl; RA represents halogen, alkyl, alkenyl, alkynyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like ; ring B represents aryl or heteroaryl; RB represents halogen, alkyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like; E1 and E2 represent an oxygen atom or the like; U represents a single bond or alkylene; X represents a group represented by Y, —SO2—Y, —O—(alkylene)—Y, —O—Z in which Y represents Z, amino or the like; Z represents cycloalkyl, heterocycloalkyl, aryl, heteroaryl or the like; or the like.

The object of the present invention is to provide an intermediate film for laminated glass which prevents reductions of transparency and appearance property caused by permeation of moisture and water. The above object is attained by the present invention, i.e., a composition for forming an intermediate film for a laminated glass which comprises ethylene-vinyl acetate copolymer and a compound having alkyleneoxy group. The composition of the present invention enables the formation of an intermediate film for a laminated glass that restrains white spots from occurring by the permeation of moisture and water.

A glass for a magnetic recording medium substrate permitting the realization of a magnetic recording medium substrate affording good chemical durability and having an extremely flat surface, a magnetic recording medium substrate comprised of this glass, a magnetic recording medium equipped with this substrate, and methods of manufacturing the same. The glass is an oxide glass not including As or F.

A liquid composition is provided for forming a thin film in the form of a mixed composite metal oxide in which a composite oxide B containing copper (Cu) and a composite oxide C containing manganese (Mn) are mixed into a composite metal oxide A represented with the general formula: Ba1-xSrxTiyO3, wherein the molar ratio B/A of the composite oxide B to the composite metal oxide A is within the range of 0.002

To provide a method for producing a magnetic disk, whereby a magnetic recording layer is formed at a high temperature. A method for producing a magnetic disk, which comprises a step of forming a magnetic recording layer on a glass substrate having a temperature of at least 550° C., wherein the glass substrate comprises, as represented by mol percentage, from 62 to 74% of SiO2, from 6 to 18% of Al2O3, from 2 to 15% of B2O3 and from 8 to 21%, in total, of at least one component selected from MgO, CaO, SrO and BaO, provided that the total content of the above seven components is at least 95%, and further contains less than 1%, in total, of at least one component selected from Li2O, Na2O and K2O, or contains none of these three components.

The disclosure relates generally to a method for fabricating a patterned medium. The method includes providing a substrate with an exterior layer under a lithographically patterned surface layer, the lithographically patterned surface layer comprising a first pattern in a first region and a second pattern in a second region, applying a first masking material over the first region, transferring the second pattern into the exterior layer in the second region, forming self-assembled block copolymer structures over the lithographically patterned surface layer, the self-assembled block copolymer structures aligning with the first pattern in the first region, applying a second masking material over the second region, transferring the polymer block pattern into the exterior layer in the first region, and etching the substrate according to the second pattern transferred to the exterior layer in the second region and the polymer block pattern transferred to the exterior layer in the first region.

Amphiphilic biomimetic phosphorylcholine-containing silicone compounds for use in both topical and internal applications as components in biomedical devices. The silicone compounds, which include zwitterionic phosphorylcholine groups, may be polymerizable or non-polymerizable. Specific examples of applications include use as active functional components in ophthalmic lenses, ophthalmic lens care solutions, liquid bandages, wound dressings, and lubricious and anti-thrombogenic coatings.

Aspects of the present invention provide a tool for analyzing and remediating an update-related failure. In an embodiment, a failure state of a computer system that has been arrived at as a result of an update is captured. A semantic diff that includes the difference between the failure state and at least one of an original state or a completion state is then computed. This semantic diff is transformed into a feature vector format. Then the transformed semantic diff is analyzed to determine a remediation for the update. Failure and/or resolution signatures can be constructed using the semantic diff and contextual data, and these signatures can be used in comparison and analysis of failures and resolutions.

Embodiments of the present invention relate to an apparatus, method, and/or sequence for a distributed ECC that may be used in a storage system. In another embodiment of the invention, an apparatus for handling distributed error correction code (ECC) operations, includes: a plurality of ECC engines configured to perform ECC operations in parallel on multiple data parts; the plurality of ECC engines distributed in parallel to receive some of the multiple data parts that are read from storage media devices and to receive some of the other multiple data parts that are to be written to the storage media devices; and the plurality of ECC engines configured to use respective ECC bytes corresponding to respective ones of the multiple data parts.

General medication disposal systems are provided. Aspects of the systems include devices having a sealable container dimensioned to accommodate a pharmaceutical composition; and an amount of an inactivating substance, e.g., granulated or pelletized activated carbon, present inside of the sealable container. Aspects of the invention further include methods of making and using the systems, as well as kits comprising the devices of the system.

Method and apparatus for disposal of used home medication which comprises an outer container being sealable and disposable containing an inner water-soluble packet/bag of gelling agent and coloring agent for stabilizing the used medication wherein the outer container comprises a foil-type container having a double sealing mechanism including a first zip lock sealing portion and a second self-sticking sealing portion to insure that the contents are safely sealed prior to disposal in a conventional home solid waste disposal unit.

A data collection unit obtains physiological data from a subject interface on a subject. The subject interface can be connected to the data collection unit. When the subject interface is connected to the data collection unit, subject interface contacts on the subject interface make contact with data collection unit contacts on the data collection unit. Some of the data collection unit contacts are for communicating physiological data from the subject interface to the data collection unit. Some of the contacts are for powering the data collection unit upon the subject interface being connected to the data collection unit and for powering down the data collection unit upon the subject interface being disconnected from the data collection unit.

A communication device includes a storage unit to store quotients and remainders associated with multiplication values obtained by multiplying a specified integer number, which is expressed in a form of (2β+α) where β is a positive integer number and α is a positive integer number other than integral multiples of 2, respectively, the quotients and the remainders being obtained by dividing the multiplication values by 2β, respectively, a first unit to divide a dividend by 2βand calculate a quotient and a remainder, a second unit to obtain a quotient, which corresponds to the remainder from the storage unit, and a third unit to determine that the data length of the packet data is normal, when a combination of the quotient and the remainder calculated by the first unit is in the storage unit.

Techniques for medium access control. Some techniques include receiving, at a first computing device, a solicitation for at least a first medium access request that specifies at least one time period for transmitting the first medium access request to the second computing device; encoding the first medium access request at least in part by using a compressive sensing encoding technique to obtain a first encoded medium access request; and transmitting the first encoded medium access request to the second computing device during the at least one time period specified in the received solicitation.

A function f(x) is calculated with a calculating apparatus that makes a correct calculation with a low probability. Provided that G and H are cyclic groups, f is a function that maps an element x of the group H into the group G, X1 and X2 are random variables whose values are elements of the group G, x1 is a realized value of the random variable X1, and x2 is a realized value of the random variable X2, an integer calculation part calculates integers a' and b' that satisfy a relation a'a+b'b=1 using two natural numbers a and b that are relatively prime. A first randomizable sampler is capable of calculating f(x)bx1 and designates the calculation result as u. A first exponentiation part calculates u'=ua. A second randomizable sampler is capable of calculating f(x)ax2 and designates the calculation result as v. A second exponentiation part calculates v'=vb. A determining part determines whether u'=v' or not. A final calculation part calculates ub'va' in a case where it is determined that u'=v'.

The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature.

Provided are a storage device, controller, and method for using host transfer rates to select a recording medium transfer rate for transferring data to a recording medium. A host transfer rate of data with respect to a buffer is measured. Provided are a plurality of recording medium transfer rates at which data is transferred between the buffer and the recording medium. A determination is made of an amount of decrease in the host transfer rate. The recording medium transfer rate is selected based on the amount of decrease in the host transfer rate. A transfer rate at which the storage device transfers data is set to the selected recording medium transfer rate.

An information processing apparatus includes a plurality of modules connected in a ring shape via a bus, and each module processes a packet flowing in a single direction on the ring in a predetermined order. The module includes a communication unit for transmitting a packet received from a first direction in the ring via the bus to a second direction, a discrimination unit for discriminating a packet from among the packets received from the first direction as a processing packet to be processed by the module, and a processing unit which is connected with the communication unit one by one and configured to process the processing packet. The communication unit transmits the packet processed by the processing unit at an interval equivalent to processing time or more for a processing packet processed by a module in a latter stage in the predetermined order among packets transmitted by the communication unit to the second direction.

The description generally relates to a system designed to synchronize the rendering of a media file between a master device and a sister device. The system is designed so that a media file is simultaneously rendered on a master device and a sister device beginning from identical temporal starting points.

A usage allocation of a hardware resource to each of a number of workloads over time is determined using a demand model. The usage allocation of the resource includes a current and past actual usage allocation of the resource, a future projected usage allocation of the resource, and current and past actual usage of the resource. A capacity allocation of the resource is determined using a capacity model. The capacity allocation of the resource includes a current and past capacity and a future projected capacity of the resource. Whether a gap exists between the usage allocation and the capacity allocation is determined using a mapping model. Where the gap exists between the usage allocation of the resource and the capacity allocation of the resource, a user is presented with options determined using the mapping model and selectable by the user to implement a remediation strategy to close the gap.

An optically active bisbenzyl compound or a racemic bisbenzyl compound represented by formula (2) that has axial chirality: where: R1 represents a halogen, or an optionally substituted: linear, branched, or cyclic C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, C6-14 aryl, C3-8 heteroaryl, linear, branched, or cyclic C1-8 alkoxy, or C7-16 aralkyl;R21 each independently represents hydrogen, halogen, nitro, or an optionally substituted: linear, branched, or cyclic C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, C6-14 aryl, linear, branched, or cyclic C1-8 alkoxy, or a C7-16 aralkyl;R3 represents hydrogen, or an optionally substituted: C6-14 aryl, a C3-8 heteroaryl, or a C7-16 aralkyl; andY2 represents a halogen, or an optionally substituted: C1-8 alkylsulfonyloxy, C6-14 arylsulfonyloxy, or C7-16 aralkylsulfonyloxy.

The present invention relates to 1,4-diethynylbenzene derivatives having substituents in the 2,3-position (cf. formula I, Claims), to the use thereof for high-frequency components, to liquid-crystalline media comprising the compounds, and to high-frequency components, in particular antennae, especially for the gigahertz range, comprising these media. The liquid-crystalline media serve, for example, for the phase shifting of microwaves for tuneable ‘phased-array’ antennae.

A processing apparatus includes an execution unit which performs computation on two operand inputs each being selectable between read data from a register and an immediate value. The processing apparatus also includes another execution unit which performs computation on two operand inputs, one of which is selectable between read data from a register and an immediate value, and the other of which is an immediate value. A control unit determines, based on a received instruction specifying a computation on two operands, whether each of the two operands specifies read data from a register or an immediate value. Depending on the determination result, the control unit causes one of the execution units to execute the computation specified by the received instruction.

A para-methoxy protected benzaldehyde useful in preparation of treprostinil, and of formula: (Formula (1)) is prepared by subjecting to Claisen re-arrangement a substituted benzaldehyde of formula (1a): (Formula (Ia)) to form the m-hydroxy-substituted benzaldehyde of formula (1b): (Formula (Ib)) and then reacting compound (1b) with a p-methoxybenzyl (PMB) compound to form a PMB-substituted benzaldehyde of formula (1).

Processes are disclosed for the conversion of a carbohydrate source to hexamethylenediamine (HMDA) and to intermediates useful for the production of hexamethylenediamine and other industrial chemicals. HMDA is produced by direct reduction of a furfural substrate to 1,6-hexanediol in the presence of hydrogen and a heterogeneous reduction catalyst comprising Pt or by indirect reduction of a furfural substrate to 1,6-hexanediol wherein 1,2,6-hexanetriol is produced by reduction of the furfural substrate in the presence of hydrogen and a catalyst comprising Pt and 1,2,6-hexanediol is then converted by hydrogenation in the presence of a catalyst comprising Pt to 1,6 hexanediol, each process then proceeding to the production of HMDA by known routes, such as amination of the 1,6 hexanediol. Catalysts useful for the direct and indirect production of 1,6-hexanediol are also disclosed.

A chemical composition for cleaning a medium is provided. For some embodiments, the chemical composition comprises a nonionic surfactant, an inorganic salt, a glycol compound, a chelating agent, and deionized water. For example, the chemical composition may comprise between about 1% and 5% of nonionic surfactant, between about 2% and 6% by weight of an inorganic salt, between about 5% and 10% by weight of a glycol compound, between about 5% and 10% by weight of a chelating agent, and deionized water.

In an intermediate connecting unit 50 of superconducting cables, by forming the connecting superconducting wires 101 in a trapezoid shape tapered in the direction of the electric insulating layer 113 (the superconducting shield layers 114) sides from the large radius section 213a side of the reinforcement insulating layer 213, the inclined surface sections 213b can be covered without spaces and without the plurality of connecting superconducting wires overlapping. The plurality of connecting superconducting wires 101 cover the inclined surface sections 213b of the reinforcement insulating layer 213 formed thicker than the radius of the cable cores 11 of the superconducting cables 10. The connecting superconducting wires 101 further connects the superconducting wires 10 arranged on the outer periphery of the large radius section 213a of the reinforcement insulating layer 213 and the superconducting wires 100 constituting the superconducting shield layers 114.

Disclosed herein are systems and methods for navigating electronic texts. According to an aspect, a method may include determining text subgroups within an electronic text. The method may also include selecting a text seed within one of the text subgroups. Further, the method may include determining a similarity relationship between the text seed and one or more adjacent text subgroups that do not include the selected text seed. The method may also include associating the text seed with the one or more adjacent text subgroups based on the similarity relationship to create a text cluster.

An information processing apparatus according to this invention, being capable of communicating with a Web server via a network, receives from the Web server a response to a processing request issued to a Web application of the Web server. The information processing apparatus changes, when screen control information described in a header of the response contains information which designates priority of a screen display by a Web browser of the information processing apparatus, priority of the screen display by the Web browser to the designated priority. When an event to display a screen other than a screen by the Web browser occurs while the Web browser presents a screen display corresponding to the response, the information processing apparatus inhibits an interrupt display by the event in order for the designated priority.

In accordance with one or more embodiments of the present disclosure, methods and apparatus are provided for flexible and user-friendly position editing of loaded media in a multi-media presentation. In one embodiment, a method for editing the position of loaded media comprises loading a page of a collage document to a client device, the page having a plurality of layers with each layer being associated with a media object, and creating a list of layers of the loaded page with each layer indexed by at least a position in the collage document. The method further includes selecting a first media object, selecting a position editing tool to group the first media object and at least one other media object adjacent to the first media object; and moving the grouped first media object and the at least one other media object to a different position in the collage document. A client device for position editing loaded media is also disclosed.

Techniques and systems for centralized access to multimedia content stored on or available to a computing device are disclosed. The centralized access can be provided by a media control interface that receives user inputs and interacts with media programs resident on the computing device to produce graphical user interfaces that can be presented on a display device.

To freely establish a peripheral equipment selection operating environment of excellent operability which can remarkably reduce an operation burden which is applied until construction information of selectable peripheral equipment can be confirmed and can easily confirm the construction information of the selectable peripheral equipment by everyone by a simple operating instruction, a CPU obtains construction information of a printer that is being selected and default setting on the basis of a selection instructing state relative to a selectable printer candidate on a network and allows them to be caption-displayed at a position near the position indicated by a cursor on a printer selection picture plane displayed on a CRT.

The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.

Methods, apparatuses and systems directed to account-based access to media services are described. A media access controller server validates a voucher for an offer of network content and issues a token permitting access to the content. A media access manager server validates the token and invokes a playlist-generation step at a publishing point, and returns the content to a user's media player. A custom plug-in on the media access manager may enforce terms of service imposed by the publisher, such as a maximum number of simultaneous streams permitted by a single voucher, or a time window for use of the voucher. Streams whose voucher's end time has expired are terminated by the plug-in.

APIs discussed herein promote efficient and timely interoperability between hardware and software components within the media processing pipelines of media content players. A PhysMemDataStructure API facilitates a hardware component's direct access to information within a memory used by a software component, to enable the hardware component to use direct memory access techniques to obtain the contents of the memory, instead of using processor cycles to execute copy commands. The PhysMemDataStructure API exposes one or more fields of data structures associated with units of media content stored in a memory used by a software component, and the exposed fields store information about the physical properties of the memory locations of the units of media content. SyncHelper APIs are used for obtaining information from, and passing information to, hardware components, which information is used to adjust the hardware components' timing for preparing media samples of synchronously-presentable media content streams.

A printing device includes a printing device side wireless communication unit configured to execute wireless communication with a mobile terminal, an operation acquisition unit configured to acquire user operation thereof, and a processor. The processor is configured to acquire operation data which is generated as the operation acquisition unit acquires a user operation, acquire establishment data which is generated as the printing device side wireless communication unit establishes a wireless communication with the mobile terminal, and issue a request control to control the printing device side wireless communication unit to transmit request data requesting the mobile terminal to transmit print data necessary for printing, via the wireless communication, when the establishment data is acquired, the request control being issued in accordance with the operation data as acquired.

A reactive rectification column suitable for the production of 2-hydroxy-4-methylmercaptobutyric acid and/or methionine contains a weir having a height of 100 mm or more.

Medical devices comprising an anti-connexin agent suitable for introduction into a subject.

The invention refers to polynucleotides selected from the group consisting of a) polynucleotides encoding for the polypeptide RBM20 comprising a P638L mutation for a human polypeptide RBM20, or a P641L mutation for a rat polypeptide RBM20, b) polynucleotides with a reverse complementary sequence of the polynucleotide of a) above, and c) polynucleotides with an identity at least 50% to a polynucleotide of a) or b) above.

RNA interference is provided for inhibition of Frizzled Related Protein-1 mRNA expression, in particular, for treating patients having glaucoma or at risk of developing glaucoma.

Arrangements for restarting data transmission on a serial low-power inter-chip media bus (SLIMbus) are presented. A clock signal may be provided in an active mode to a component communicatively coupled with the SLIMbus. Immediately prior to the clock signal in the active mode being provided, the clock signal may have been in a paused mode. While the clock signal was in the paused mode at least until the clock signal is provided in the active mode, the data line may have been inactive (e.g., a toggle on the data line may not have been present). Frame synchronization data for a frame may be transmitted. The frame synchronization data for the frame, as received by the component, may not match expected frame synchronization data. Payload data may be transmitted as part of the frame to the component, wherein the payload data is expected to be read properly by the component.

A system for facilitating remote medical diagnosis and consultation of heart disease for a patient, the system comprising: a diagnostic device for performing Electrocardiography on the patient, a network device in communication with the diagnostic device via wired or wireless communication links, a software program pre-installed in the network device, a server located remotely, wherein during operation, the patient activates the diagnostic device which will perform Electrocardiography on the patient, the diagnostic device receives diagnostic data and transmits the diagnostic data to the network device, the software program transmit the diagnostic data to over a network to a server which a physician have access to, and based on the diagnostic data gathered by the server and some additional medical data, the physician can review the patient's health condition and offer an appropriate feedback and diagnosis for the patient.

Provided is an amide ester that is useful as an intermediate manufacturing product for an aroma compound such as spilanthol or the like. Also provided is a spilanthol manufacturing method using said amide ester. High-purity spilanthol can be manufactured by reacting an amide ester represented by general formula (1) with a basic compound. (In the formula, R1 represents a C1-6 alkyl group or a phenyl group that may be substituted with a C1-4 alkyl group, a C1-4 alkoxy group, or a halogen atom; R2 represents a C1-8 hydrocarbon group; and the wavy lines represent cis configurations, trans configurations, or a mixture of the two configurations.)

Chiral amino compounds, methods of preparation and uses thereof. Tamiflu can be obtained from the said compounds. Multi-substituted chiral tetrahydropyrrolyl amine which can be used as intermediate compounds of medicament can also be produced by the said compounds.