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Cadmium isotope fractionation reveals genetic variation in Cd uptake and translocation by <i>Theobroma cacao</i> and role of natural resistance-associated macrophage protein 5 and heavy metal ATPase-family transporters




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Genes and genomes and unnecessary complexity in precision medicine




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Genetic structure in hybrids and progenitors provides insight into processes underlying an invasive cattail (<i>Typha</i> × <i>glauca</i>) hybrid zone




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The complex genetic architecture of male mate choice evolution between <i>Drosophila</i> species




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Reinventing quantitative genetics for plant breeding: something old, something new, something borrowed, something BLUE




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Targeted conservation genetics of the endangered chimpanzee




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AAV-mediated cardiac gene transfer of wild-type desmin in mouse models for recessive desminopathies




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Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect




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Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy




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Treating osteoarthritis via gene therapy with rejuvenation factors




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Gene therapy for cardiovascular diseases in China: basic research




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Gene Therapy




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The genetics of macrophage activation syndrome




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Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat




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Genes & Immunity




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Finding a unifying SLE expression signature in a sea of heterogeneity




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Genetic and clinical correlates of entosis in pancreatic ductal adenocarcinoma




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Mucinous carcinoma with micropapillary features is morphologically, clinically and genetically distinct from pure mucinous carcinoma of breast




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An analysis of the effect of mu-opioid receptor gene (<i>OPRM1</i>) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence




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Identification of gene modules associated with survival of diffuse large B-cell lymphoma treated with CHOP-based chemotherapy




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Combining clinical and candidate gene data into a risk score for azathioprine-associated leukopenia in routine clinical practice




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Mechanisms of graft-versus-leukemia effects after allogeneic stem cell transplantation: effects on the leukemia stem cell?




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Deconvoluting MLL1-dependent pathways in hematopoiesis and leukemogenesis




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To Sleep, Perchance to Gene

Researchers identify genes linked to rapid eye movement sleep




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Basement membrane remodelling regulates mouse embryogenesis




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Oncogene




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CDK11 is required for transcription of replication-dependent histone genes




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Author Correction: Metabolic activity analyses demonstrate that Lokiarchaeon exhibits homoacetogenesis in sulfidic marine sediments




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Principal Investigator/Professor Positions at Max-Planck Center for Tissue Stem Cell Research and Regenerative Medicine, GDL

With a generous support from the Guangzhou City Government and the Guangdong Provincial Government, Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL) was launched in 2017. GRMH-GDL aims to bring together multiple leading scientific research units from Guangdong, Hong Kong, Macao and well-known international research institutes to achieve the vital goal of "Healthy China" and to cooperatively tackle the scientific and technical problems and challenges. GRMH-GDL is focused…




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Author Correction: Genetic circuit design automation for the gut resident species <i>Bacteroides thetaiotaomicron</i>




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Tissue-specific alteration of gene expression and function by RU486 and the GeneSwitch system




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Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in <i>Drosophila</i>




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Repository of proposed pathways and protein–protein interaction networks in age-related macular degeneration




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Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




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Oral health in allogeneic hematopoietic stem cells transplantation survivors




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism




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NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas




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Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC)

In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins.




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FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome




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MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis




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Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice




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Cancer Gene Therapy




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Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity




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New insights into K<sub>ATP</sub> channel gene mutations and neonatal diabetes mellitus




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Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder




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Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human




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Efficient generation of mouse models with the prime editing system




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Mendelian neurodegenerative disease genes involved in autophagy




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Expert opinion—management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors