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Recovery for brands look difficult as anxious consumers maintain distance

India among the top 3 nervous nations in the world; consumers expect long-term spending to be hit, want brands to spread optimism and cheer: Kantar




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Everything under : a novel / Daisy Johnson

Johnson, Daisy, 1990- author




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The man who saw everything / Deborah Levy

Levy, Deborah, author




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[ASAP] Continuous Flow Conditions for High Temperature Formation of a Benzodioxan Pharmaceutical Intermediate: Rapid Scaleup for Early Phase Material Delivery

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00499




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A polymeric nanocarrier with a tumor acidity-activatable arginine-rich (R9) peptide for enhanced drug delivery

Biomater. Sci., 2020, 8,2255-2263
DOI: 10.1039/D0BM00069H, Paper
Liting Zhang, Chengtao Jiang, Fanjun Zeng, Haiyu Zhou, Dongdong Li, Xinyu He, Song Shen, Xianzhu Yang, Jun Wang
The cell-penetrating function of R9 peptide of DA@R9-NPDOX was masked in the blood circulation, while reactivated in tumor tissue for enhanced tumor cellular uptake.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tumor-targeting peptide functionalized PEG-PLA micelles for efficient drug delivery

Biomater. Sci., 2020, 8,2274-2282
DOI: 10.1039/C9BM02036E, Paper
Yue Cai, Zhuomin Xu, Qi Shuai, Fangtao Zhu, Jiao Xu, Xin Gao, Xuanrong Sun
PEG-PLA micelles are modified with F3 peptides, thus endowing the micelles with active-targeting ability due to the nucleolin-binding ability of the F3 peptides.
The content of this RSS Feed (c) The Royal Society of Chemistry




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An acoustic/thermo-responsive hybrid system for advanced doxorubicin delivery in tumor treatment

Biomater. Sci., 2020, 8,2202-2211
DOI: 10.1039/C9BM01794A, Paper
Li Zhang, Shiyu Zhang, Huajian Chen, Yu Liang, Bingxia Zhao, Wanxian Luo, Qian Xiao, Jinheng Li, Junqiao Zhu, Chao Peng, Yaru Zhang, Zhe Hong, Ying Wang, Yingjia Li
Ultrasound-assisted fast extravasation and the following laser-triggered drug release of thermo-sensitive liposomes synergistically enhanced drug delivery in deep tumors.
The content of this RSS Feed (c) The Royal Society of Chemistry




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From single to a dual-gene delivery nanosystem: coordinated expression matters for boosting the neovascularization in vivo

Biomater. Sci., 2020, 8,2318-2328
DOI: 10.1039/C9BM02000D, Paper
Bin Gao, Xiaoyu Wang, Meiyu Wang, Xiang-kui Ren, Jintang Guo, Shihai Xia, Wencheng Zhang, Yakai Feng
A dual-gene delivery system with coordinated expression function boosted the neovascularization.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00015A, Paper
Manisha Ahir, Priyanka Upadhyay, Avijit Ghosh, Sushmita Sarker, Saurav Bhattacharya, Payal Gupta, Swatilekha Ghosh, Sreya Chattopadhyay, Arghya Adhikary
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Development of new self-assembled cationic amino liposomes for efficient gene delivery

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00331J, Communication
Yihang Wu, Yue Xiong, Ling Wang, Quanming Zhou, Linxian Li, Pavel A. Levkin, Gary Davidson, Liqian Gao, Wenbin Deng
A library of lipidoids self-assembling to liposomes exhibits excellent transfection efficiency in HEK 293T cells and mESCs with low cytotoxicity.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Messenger RNA/polymeric carrier nanoparticles for delivery of heme oxygenase-1 gene in the post-ischemic brain

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00076K, Paper
Jungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung Lee
Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Long-term delivery of alendronate through an injectable tetra-PEG hydrogel to promote osteoporosis therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00376J, Paper
Dawei Li, Jin Zhou, Mingming Zhang, Yuanzheng Ma, Yanyu Yang, Xue Han, Xing Wang
An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Core–shell particles for drug-delivery, bioimaging, sensing, and tissue engineering

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01872G, Review Article
Ratchapol Jenjob, Treethip Phakkeeree, Daniel Crespy
Core–shell particles offer significant advantages in their use for bioimaging and biosensors.
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A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00204F, Paper
Yongju He, Linjie Shao, Ibrahim Usman, Yao Hu, Anqiang Pan, Shuquan Liang, Hui Xu
The dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Trastuzumab targeted micellar delivery of docetaxel using dendron–polymer conjugates

Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper
Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis

Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper
Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Particle-mediated delivery of frataxin plasmid to a human sensory neuronal model of Friedreich's ataxia

Biomater. Sci., 2020, 8,2398-2403
DOI: 10.1039/C9BM01757G, Communication
Ewa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank Caruso
Multilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper
Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper
Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Covid-19 lockdown effect: Every second Indian now on internet in cities

The data released by Nielsen and the Broadcast Audience Research Council (BARC) shows that internet usage has grown sharply in cities over the last one month, touching 54 per cent




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RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10673A, Paper
Amit S. Yadav, N. Naga Venkata Radharani, Mahadeo Gorain, Anuradha Bulbule, Dattatrya Shetti, Gaurab Roy, Thejus Baby, Gopal C. Kundu
Peptide functionalized pH sensitive raloxifene-chitosan nanoparticles with high biocompatibility synergistically inhibit tumor growth and angiogenesis in breast cancer.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy

Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper
Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effective atherosclerotic plaque inflammation inhibition with targeted drug delivery by hyaluronan conjugated atorvastatin nanoparticles

Nanoscale, 2020, 12,9541-9556
DOI: 10.1039/D0NR00308E, Paper
Seyedmehdi Hossaini Nasr, Zahra Rashidijahanabad, Sherif Ramadan, Nate Kauffman, Narayanan Parameswaran, Kurt R. Zinn, Chunqi Qian, Ripla Arora, Dalen Agnew, Xuefei Huang
Atherosclerosis is associated with inflammation in the arteries. Hyaluronan atorvastatin nanoparticle conjugate could target CD44 overexpressed in atherosclerotic plaques and significantly reduce plaque associated inflammation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Near-infrared nanosecond-pulsed laser-activated high efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01792B, Paper
Tuhin Subhra Santra, Srabani Kar, Chih-Wei Chen, Jayant Borana, Te-Chang Chen, Ming-Chang Lee, Fan-Gang Tseng
Here, efficient intracellular delivery of molecules with high cell viability is reported using nanosecond-pulsed laser-activated plasmonic photoporation mediated by high-aspect-ratio nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles (nm-AuPNPs) at near-infrared wavelength. Upon...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The role of the aged in community recovery following Hurricane Andrew




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The recovery of schools from earthquake effects




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Self organization in disaster response and recovery




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Community recovery from a major natural disaster




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Race, religion, and ethnicity in disaster recovery




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Diversity, abundance, biomass, and the presence of certain families of aquatic insects as bioindicators of stream recovery from a pollution source




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The marriage record of Bryant, Eavery and Blocker, Nellie A




very

Inscribed: "Yours very sincerely" [Eric Morgan]




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Iris ; a very ornate inner label by F. Garcia and Bros.




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El Carpio; a very ornate outer label.




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F. Garcia and Bros: a very ornate outer cigar label




very

Could Be Very Potent




very

Unidentified entertainer at the Columbia wears a very short dress




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Parade of men in coats, ties, and straw hats carrying signs: Realtors, Our Flowers Never Die, Sunworshippers Every One, No Wonder Lew Brown Is Happy; spectators include boy on crutches, man in tank top [like volleyball player from #457], woman in flowered




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Young women in bathing suits standing in a line with group of boy scouts; sign, "Enjoy Outdoor Sports Every Day."




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Everyday is a golf day at Hotel Charlotte Harbor, Punta Gorda




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Haven Hotel -fire proof, modern in every appointment- Winter Haven, Florida




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Corvery, Thomas L




very

Turner and Wilson Coffee delivery wagon




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Coca-cola delivery truck with driver and passenger




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Glass delivery truck crossing the Gandy Bridge




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Delivery trucks at the Tampa Arctic Ice Company, Inc.




very

Fur trader's discovery, or, The brotherhood of thieves




very

Frank Reade, Jr., in the sea of sand and his discovery of a lost people




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Synthesis and characterization of potential drug delivery systems using nonionic surfactant "niosome"




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Applying the wrapper approach for auto discovery of under-sampling and over-sampling percentages on skewed datasets