bal Fantasy Football start/sit tips Week 9: Adrian Peterson won’t slow down against the Falcons By www.washingtonpost.com Published On :: Wed, 31 Oct 2018 14:24:19 +0000 Six teams are on a bye this week, giving stars like Saquon Barkley, Odell Beckham Jr., Andrew Luck, Zach Ertz and A.J. Green the week off. Here are three players that could have big games in their stead. Full Article
bal College Football Playoff projections: Alabama, Clemson at the top, but don’t count out Tier 2 By www.washingtonpost.com Published On :: Tue, 06 Nov 2018 16:32:38 +0000 Michigan, Georgia and Oklahoma scrambling for final spots. Full Article
bal The Kansas Jayhawks' inside-outside game makes them a major threat for the NCAA basketball title By www.washingtonpost.com Published On :: Tue, 06 Nov 2018 19:42:45 +0000 The key could be Dedric Lawson, a 6-foot-9 forward who sat out last season after transferring from Memphis and is the best transfer Coach Bill Self has landed in his time in Lawrence. Full Article
bal Fantasy Football start/sit tips Week 10: Bench all Redskins players. Like now. By www.washingtonpost.com Published On :: Wed, 07 Nov 2018 15:22:22 +0000 It's a bad week to own a Washington skill position player, but a great time to get Tevin Coleman and other into your lineup. Full Article
bal The fantasy football players you need in your Week 12 lineup By www.washingtonpost.com Published On :: Wed, 21 Nov 2018 14:30:05 +0000 Last Sunday, Jameis Winston started the game on the Buccaneers' bench. Here's why he needs to be in your lineup this week. Full Article
bal Fantasy Football start/sit tips Week 12: Cowboys will have no trouble stopping the Redskins By www.washingtonpost.com Published On :: Wed, 21 Nov 2018 15:07:29 +0000 Washington will be without their starting right guard, right tackle, left guard, left tackle, center and starting quarterback on Sunday, making the Dallas defense a very solid pickup. Full Article
bal Fantasy Football start/sit tips Week 13: Backup running backs take center stage By www.washingtonpost.com Published On :: Wed, 28 Nov 2018 14:34:03 +0000 If you were relying on Jaguars running back Leonard Fournette to help you this week you’re going to need a back up plan. Full Article
bal The fantasy football players you need in your lineup for Week 14 By www.washingtonpost.com Published On :: Wed, 05 Dec 2018 15:10:53 +0000 There are a number of players with favorable matchups this week, but none as palatable as Cowboys WR Amari Cooper. Full Article
bal Fantasy Football start/sit tips Week 14: Trust Kirk Cousins over Andrew Luck, Cam Newton By www.washingtonpost.com Published On :: Wed, 05 Dec 2018 15:41:49 +0000 Cousins's next opponent, the Seattle Seahawks, has been kind to fantasy quarterbacks of late, surrendering at least 21 fantasy points in each of the last four contests. Full Article
bal Week 15 waiver wire tips: Two helpful defenses available for the fantasy football playoffs By www.washingtonpost.com Published On :: Sun, 09 Dec 2018 21:33:03 +0000 The fantasy football regular season has come to an end but that doesn’t make the waiver wire any less important, especially if you have been streaming quarterbacks and defenses to make it this far. Full Article
bal Latest NFL playoff projections: Seahawks, Vikings can shake things up on Monday Night Football By www.washingtonpost.com Published On :: Mon, 10 Dec 2018 14:50:47 +0000 The two teams in control of the NFC's wild-card slots battle head-to-head, while the rest of the NFL playoff picture got much clearer despite four of the AFC’s top teams losing. Full Article
bal Harold Baines does not deserve a spot in baseball’s Hall of Fame. Period. By www.washingtonpost.com Published On :: Mon, 10 Dec 2018 15:58:15 +0000 Baines, a six-time all-star, led the league in a batting category just once over a 22-year career. If that' the new bar for the Hall, it's time to talk about Freddy Garcia and Placido Polanco, too. (Note: It should never be time to talk about Freddy Garcia and Placido Polanco.) Full Article
bal Fantasy Football start/sit tips Week 15: Starting Aaron Rodgers will lead to disappointment By www.washingtonpost.com Published On :: Wed, 12 Dec 2018 16:37:58 +0000 It's never easy benching star players who are in less-than-ideal situations but it is often the right thing to do. Full Article
bal The fantasy football players you need in your lineup for Week 15 By www.washingtonpost.com Published On :: Wed, 12 Dec 2018 17:06:32 +0000 Full Article
bal College football playoffs and bowl game ATS picks By www.washingtonpost.com Published On :: Fri, 14 Dec 2018 12:54:41 +0000 Alabama and Clemson appear to be on a collision course ending at the College Football Playoff championship game on Jan. 7 at Levi’s Stadium. Full Article
bal Week 16 waiver wire tips: Surprisingly solid options to win your fantasy football league By www.washingtonpost.com Published On :: Sun, 16 Dec 2018 21:20:33 +0000 Sleep easy knowing that no matter what next week’s injury report reveals, you will have the players you need to secure a year’s worth of bragging rights. Full Article
bal Fantasy Football start/sit tips Week 16: Bench Tom Brady. We know, but just do it. By www.washingtonpost.com Published On :: Wed, 19 Dec 2018 16:06:23 +0000 The Patriots quarterback has been sensational for years, but with everything on the line for your fantasy season in Week 16, he's a liability. Full Article
bal Drag queens, voguing and thongs: First annual Hirshhorn Ball ushers in a new kind of D.C. party By www.washingtonpost.com Published On :: Sun, 16 Jun 2019 19:10:55 +0000 Unlike most D.C. galas where the political powerhouses steal the spotlight, drag queens reigned supreme at this shindig. Full Article
bal Michelle Obama goes low and leads Team USA to victory in celebrity dodgeball match on ‘Late Late Show’ By www.washingtonpost.com Published On :: Tue, 18 Jun 2019 17:03:07 +0000 The former first lady and her A-list friends triumphed over late-night host James Corden and his squad. Full Article
bal Presidential hopefuls swap the campaign trail for the field at Congressional Women’s Softball Game By www.washingtonpost.com Published On :: Thu, 20 Jun 2019 20:25:45 +0000 The Members team ultimately fell 10-4 to the press team, despite valiant efforts from players such as 2020 presidential hopeful and team pitcher Kirsten Gillibrand. Full Article
bal A ball fit for Cinderella at the Library of Congress as the National Film Registry inducts the classic film By www.washingtonpost.com Published On :: Sun, 23 Jun 2019 16:15:40 +0000 Fans of the Disney animated movie celebrated its addition to the National Film Registry. Full Article
bal Harry and Meghan make surprise appearance at major league baseball game in London By www.washingtonpost.com Published On :: Sun, 30 Jun 2019 19:36:01 +0000 The new parents showed up at the first official MLB game in Europe on Saturday. Full Article
bal 10 Things Not To Do On A Cruise Ship Balcony (Ever!) By tips4travellers.libsyn.com Published On :: Mon, 09 Sep 2019 04:00:00 +0000 Discover the 10 things that you should never do on a cruise ship balcony. Some of them are rules from the cruise line, which if you break you could find yourself thrown off your cruising vacation (or even banned by the cruise line for life!). Some are things that will make your and the other cruisers around you have a more enjoyable cruise. And some even could save you a lot of embarrassment.... ** Buy my Cruise T-shirts: http://bit.ly/TFTStore ** USA cruisers get great cruise deals CRUISEDIRECT.COM: http://bit.ly/TFTBookCruise ** UK Cruisers get great cruise deals with CRUISE.CO.UK: http://bit.ly/BookCruiseUK Gary Bembridge's Tips For Travellers aims to help you make more of your precious travel time and money on land and when cruising the oceans or rivers of the world. To help you, in every video I draw on my first-hand tips and advice from travelling every month for over 20 years and 60+ cruises. Follow Tips For Travellers on: - Instagram: http://www.instagram.com/garybembridge - Facebook: http://www.facebook.com/tipsfortravellers - Twitter: http://www.twitter.com/garybembridge Full Article
bal Report: MRG Ranks Global IPTV Market Leaders By www.tvover.net Published On :: Thu, 08 Nov 2012 22:57:47 GMT MRG is excited to release its highly comprehensive annual study IPTV Market Leader Report by Product and Region — Fall 2012. MRG’s IPTV Market Leader Reports identify which IPTV systems and software companies are leading each of the six IPTV market segments: access systems, video headend systems, video-on-demand server software, set-top boxes, middleware, and content protection/digital rights management. The data is further segmented by geographic region as follows: North America, Latin America/Caribbean, Western Europe, Eastern Europe, Asia Pacific and the Middle East/Africa. “IPTV is continuing its rapid growth worldwide but some of the more exciting opportunities are only just beginning in the Middle East/Africa and Latin America/Caribbean regions,” said Jose Alvear, Senior Research Analyst at MRG. “While the growth in the number of new IPTV service providers has been slowing down because telcos around the world have already deployed IPTV services for a number of years, there are still plenty of new opportunities available to vendors in emerging markets. In addition, vendors are now supplying multi-screen, content delivery and OTT services, as the global pay-TV industry continues to evolve into new screens and devices.” Full Article IPTV Reports
bal Trump’s proposed tennis ball tariff represents a grand slam of terrible trade policy By www.washingtonpost.com Published On :: Thu, 27 Jun 2019 19:24:22 +0000 His unforced errors would make it hard on a U.S. manufacturer. Full Article
bal A global recession is likely here. Lawmakers need to do their jobs. By www.washingtonpost.com Published On :: Mon, 16 Mar 2020 23:13:02 +0000 Policymakers need to step up and do something useful — yesterday. Full Article
bal oscon: RT @oreillyanimals Vote Instant Wild's Digital Eyes & Ears for Wildlife Protection to win Google Global Impact Award http://t.co/BM3qufX1PF By twitter.com Published On :: Thu, 23 May 2013 17:36:51 +0000 oscon: RT @oreillyanimals Vote Instant Wild's Digital Eyes & Ears for Wildlife Protection to win Google Global Impact Award http://t.co/BM3qufX1PF Full Article
bal strataconf: A roundup from the data journalism beat http://t.co/y8RVUwHO4G Global open data, scholarships, mapping a civil war & more #strataconf By twitter.com Published On :: Thu, 06 Jun 2013 21:36:47 +0000 strataconf: A roundup from the data journalism beat http://t.co/y8RVUwHO4G Global open data, scholarships, mapping a civil war & more #strataconf Full Article
bal strataconf: Innovative ways journalists are using data to tell stories http://t.co/y8RVUwHO4G Global open data, scholarships, mapping a civil war & more By twitter.com Published On :: Sun, 09 Jun 2013 11:25:28 +0000 strataconf: Innovative ways journalists are using data to tell stories http://t.co/y8RVUwHO4G Global open data, scholarships, mapping a civil war & more Full Article
bal Prior Knowledge, Or He Isn't Going to Pick on the Baseball Study By feedproxy.google.com Published On :: Mon, 16 Mar 2020 11:55:19 EDT Teacher question: You wrote recently that it was a good idea to teach comprehension skills, but our school district says we shouldn’t, that it’s prior knowledge that matters. Do you know the baseball study? Have you read Natalie Wexler’s research? It is really difficult to trust research when everyone tells us something different. Shanahan's response: I feel your pain. Full Article
bal New Global OReilly Report Finds 85% of Organizations Are Evaluating or Using Artificial Intelligence in Production By www.oreilly.com Published On :: Wed, 18 Mar 2020 11:10:29 PDT Full Article
bal Prior Knowledge, Or He Isn't Going to Pick on the Baseball Study By feedproxy.google.com Published On :: Mon, 16 Mar 2020 11:55:19 EDT Teacher question: You wrote recently that it was a good idea to teach comprehension skills, but our school district says we shouldn’t, that it’s prior knowledge that matters. Do you know the baseball study? Have you read Natalie Wexler’s research? It is really difficult to trust research when everyone tells us something different. Shanahan's response: I feel your pain. Full Article
bal News24.com | China supports WHO-led review of global pandemic response By www.news24.com Published On :: Fri, 08 May 2020 20:11:02 +0200 China says it supports a World Health Organisation-led review into the global response to the coronavirus outbreak, but only "after the pandemic is over". Full Article
bal velocityconf: Free webcast from our friends at @citrix 5/29 http://t.co/IOeY4U0wUP Learn to consolidate 40 load balancers and ADCs into single platform By feedproxy.google.com Published On :: Tue, 21 May 2013 15:01:58 +0000 velocityconf: Free webcast from our friends at @citrix 5/29 http://t.co/IOeY4U0wUP Learn to consolidate 40 load balancers and ADCs into single platform Full Article
bal velocityconf: RT @oreillyanimals Vote Instant Wild's Digital Eyes & Ears for Wildlife Protection to win Google Global Impact Award http://t.co/Z0EetiQshZ By feedproxy.google.com Published On :: Thu, 23 May 2013 17:35:35 +0000 velocityconf: RT @oreillyanimals Vote Instant Wild's Digital Eyes & Ears for Wildlife Protection to win Google Global Impact Award http://t.co/Z0EetiQshZ Full Article
bal News24.com | LIVE | Covid-19: Ramaphosa to visit epicentre Western Cape, Global death toll passes 275 000 By www.news24.com Published On :: Sat, 09 May 2020 19:27:05 +0200 Stay up to date with the latest news, views and analysis as the number of coronavirus cases in SA increases. Full Article
bal AT#237 - Travel to Bali in Indonesia By asia.amateurtraveler.com Published On :: Sat, 19 Jun 2010 14:00:00 +0000 The Amateur Traveler talks to Sam Oppenheim who makes a rare 4th appearance on the show to talk about Bali in Indonesia. Sam started his exploration of Bali in Ubud which is the cultural capital of the area. He met two of the people mentioned in the popular book Eat, Pray, Love: Wayan and Ketut Liyer. In Ubud he attended some of the traditional Balinese dances (Legong, Barong and Kecak). Sam explored the Hindu temples and the resort area of Kuta Beach with its famous nightlife, dove a ship wreck and explored the island by motorcycle. Sam’s does regret was not getting down to Nusa Dua on the southern tip with its wonderful sunsets or out to Komodo. Full Article
bal AT#438 - Travel to Baltimore, Maryland By usa.amateurtraveler.com Published On :: Sat, 27 Sep 2014 19:10:09 +0000 Hear about travel to Baltimore, Maryland as the Amateur Traveler talks to Nancy Parode from about.com. Nancy has lived in the Baltimore area for a total of about 12 years and tells us about her adopted hometown. Full Article
bal AT#524 - Hiking the Peaks of the Balkans (Albania, Kosovo, Montenegro) By europe.amateurtraveler.com Published On :: Sat, 13 Aug 2016 14:00:00 +0000 Hear about hiking the Peaks of the Balkans trail in Albania, Kosovo, and Montenegro as the Amateur Traveler talks to Dan and Audrey from uncorneredmarket.com about this off the beaten track route in Europe. Full Article
bal AT#525 - Baltic Cruise with Viking Ocean By europe.amateurtraveler.com Published On :: Sat, 20 Aug 2016 14:00:00 +0000 Hear about a Baltic Cruise on Viking Ocean as the Amateur Traveler talks to Mary Jo Manzanares from travelingwithmj.com about their recent Viking Homelands cruise on the Viking Sea. Full Article
bal AT#649 - Travel to Bali By amateurtraveler.com Published On :: Sat, 16 Mar 2019 14:00:00 +0000 Hear about travel to the Island of Bali in Indonesia as the Amateur Traveler talks to David Brodie from TravelIn10.com about a recent family trip to this popular tropical destination. Full Article
bal Sport24.co.za | Haiti football federation boss probed for alleged rape of girls By www.sport24.co.za Published On :: Sat, 09 May 2020 18:12:58 +0200 Police in Haiti are investigating allegations that the president of the national football federation raped teenage girls. Full Article
bal Sport24.co.za | Phillies star lashes 'dumb' rule: Let baseball stars play Olympics By www.sport24.co.za Published On :: Sat, 09 May 2020 19:29:04 +0200 Philadelphia Phillies star Bryce Harper believes Major League Baseball should relax its "dumb" rule preventing top players from competing in the Olympics. Full Article
bal The UK Global Tariff By feedproxy.google.com Published On :: Fri, 06 Mar 2020 09:05:01 +0000 Research Event 18 March 2020 - 9:00am to 10:00am Chatham House | 10 St James's Square | London | SW1Y 4LE Event participants Michael Gasiorek, Professor of Economics, UKTPO Fellow, University of Sussex; Director, InteranalysisJulia Magntorn Garrett, Research Officer, UKTPO, University of SussexAllie Renison, Head of Europe and Trade Policy at the Institute of DirectorsMaximiliano Mendez-Parra, Senior Research Fellow, Overseas Development InstituteChair: Professor Jim Rollo, Associate Fellow, Global Economy and Finance Department, Chatham House; Deputy Director, UK Trade Policy Observatory The UK government’s public consultation on tariffs closes on 5 March. This meeting will discuss the proposals floated in the consultation document and consider their effects on tariff and protection levels, prices and variety. It will also place tariff policy in the wider context of trade policy, including the UK’s future trading relationship with the EU and the USA. Department/project Global Economy and Finance Programme, UK Trade Policy Observatory Michela Gariboldi Research Assistant, Global Economy and Finance Programme 02073143692 Email Full Article
bal Coronavirus: Global Response Urgently Needed By feedproxy.google.com Published On :: Sun, 15 Mar 2020 14:33:11 +0000 15 March 2020 Jim O'Neill Chair, Chatham House Robin Niblett Director and Chief Executive, Chatham House @RobinNiblett Creon Butler Research Director, Trade, Investment & New Governance Models: Director, Global Economy and Finance Programme LinkedIn There have been warnings for several years that world leaders would find it hard to manage a new global crisis in today’s more confrontational, protectionist and nativist political environment. 2020-03-15-Korea-Stock-Exchange.jpg A currency dealer wearing a face mask monitors exchange rates in front of a screen showing South Korea's benchmark stock index in Seoul on March 13, 2020. Photo by JUNG YEON-JE/AFP via Getty Images. An infectious disease outbreak has long been a top national security risk in several countries, but the speed and extent of COVID-19’s spread and the scale of its social and economic impact has come as an enormous and deeply worrying shock.This pandemic is not just a global medical and economic emergency. It could also prove a decisive make-or-break point for today’s system of global political and economic cooperation.This system was built up painstakingly after 1945 as a response to the beggar-thy-neighbour economic policies of the 1930s which led to the Second World War. But it has been seriously weakened recently as the US and China have entered a more overt phase of strategic competition, and as they and a number of the other most important global and regional players have pursued their narrowly defined self-interest.Now, the disjointed global economic response to COVID-19, with its enormous ramifications for global prosperity and economic stability, has blown into the open the urgent need for an immediate reaffirmation of international political and economic cooperation.What is needed is a clear, coordinated and public statement from the leaders of the world’s major countries affirming the many things on which they do already agree, and some on which they should be able to agree.In particular that:they will give the strongest possible support for the WHO in leading the medical response internationally;they will be transparent and tell the truth to their peoples about the progress of the disease and the threat that it represents;they will work together and with the international financial institutions to provide businesses, particularly SMEs, and individuals whatever support they need to get through the immediate crisis and avoid long-term damage to the global economy; they will ensure the financial facilities for crisis support to countries - whether at global or regional level - have whatever resources they need to support countries in difficulty;they will avoid new protectionist policies - whether in trade or finance;they commit not to forget the poor and vulnerable in society and those least able to look after themselves.Such a statement could be made by G20 leaders, reflecting the group’s role since 2010 as the premier forum for international economic cooperation.But it could be even more appropriate coming from the UN Security Council, recognising that COVID-19 is much more than an economic challenge; and also reflecting the practical fact, in a time when international travel is restricted, the UNSC has an existing mechanism in New York to negotiate and quickly agree such a statement.A public statement by leading countries could do a great deal to help arrest a growing sense of powerlessness among citizens and loss of confidence among businesses worldwide as the virus spreads.It could also set a new course for international political and economic cooperation, not just in relation to the virus, but also other global threats with potentially devastating consequences for economic growth and political stability in the coming years. Full Article
bal To Advance Trade and Climate Goals, ‘Global Britain’ Must Link Them By feedproxy.google.com Published On :: Thu, 19 Mar 2020 17:12:54 +0000 19 March 2020 Carolyn Deere Birkbeck Associate Fellow, Global Economy and Finance Programme, and Hoffmann Centre for Sustainable Resource Economy @carolyndeere LinkedIn Google Scholar Dr Emily Jones Associate Professor, Blavatnik School of Government Dr Thomas Hale Associate Professor, Blavatnik School of Government COVID-19 is a sharp reminder of why trade policy matters. As the UK works to forge new trade deals, it must align its trade policy agenda with its climate ambition. 2020-03-19-Boris-Johnson-COP26.jpg Boris Johnson at the launch of the UK-hosted COP26 UN Climate Summit at the Science Museum, London on February 4, 2020. Photo by Jeremy Selwyn - WPA Pool/Getty Images. COVID-19 is a sharp reminder of why trade and climate policy matters. How can governments maintain access to critical goods and services, and ensure global supply chains function in times of crisis?The timing of many trade negotiations is now increasingly uncertain, as are the UK’s plans to host COP26 in November. Policy work continues, however, and the EU has released its draft negotiating text for the new UK-EU trade deal, which includes a sub-chapter specifically devoted to climate. This is a timely reminder both of the pressing need for the UK to integrate its trade and climate policymaking and to use the current crisis-induced breathing space in international negotiations - however limited - to catch up on both strategy and priorities on this critical policy intersection.The UK government has moved fast to reset its external trade relations post-Brexit. In the past month it formally launched bilateral negotiations with the EU and took up a seat at the World Trade Organization (WTO) as an independent member. Until the COVID-19 crisis hit, negotiations were also poised to start with the US.The UK is also in the climate spotlight as host of COP26, the most important international climate negotiation since Paris in 2015, which presents a vital opportunity for the government to show leadership by aligning its trade agenda with its climate and sustainability commitments in bold new ways.Not just an empty aspirationThis would send a signal that ‘Global Britain’ is not just an empty aspiration, but a concrete commitment to lead.Not only is concerted action on the climate crisis a central priority for UK citizens, a growing and increasingly vocal group of UK businesses committed to decarbonization are calling on the government to secure a more transparent and predictable international market place that supports climate action by business.With COP26, the UK has a unique responsibility to push governments to ratchet up ambition in the national contributions to climate action – and to promote coherence between climate ambition and wider economic policymaking, including on trade. If Britain really wants to lead, here are some concrete actions it should take.At the national level, the UK can pioneer new ways to put environmental sustainability – and climate action in particular - at the heart of its trade agenda. Achieving the government’s ambitious Clean Growth Strategy - which seeks to make the UK the global leader in a range of industries including electric cars and offshore wind – should be a central objective of UK trade policy.The UK should re-orient trade policy frameworks to incentivize the shift toward a more circular and net zero global economy. And all elements of UK trade policy could be assessed against environmental objectives - for example, their contribution to phasing out fossil fuels, helping to reverse overexploitation of natural resources, and support for sustainable agriculture and biodiversity.In its bilateral and regional trade negotiations, the UK can and should advance its environment, climate and trade goals in tandem, and implementation of the Paris Agreement must be a core objective of the UK trade strategy.A core issue for the UK is how to ensure that efforts to decarbonise the economy are not undercut by imports from high-carbon producers. Here, a ‘border carbon adjustment (BCA)’ - effectively a tax on the climate pollution of imports - would support UK climate goals. The EU draft negotiating text released yesterday put the issue of BCAs front and centre, making crystal clear that the intersection of climate, environment and trade policy goals will be a central issue for UK-EU trade negotiations.Even with the United States, a trade deal can and should still be seized as a way to incentivize the shift toward a net zero and more circular economy. At the multilateral level, as a new independent WTO member, the UK has an opportunity to help build a forward-looking climate and trade agenda.The UK could help foster dialogue, research and action on a cluster of ‘climate and trade’ issues that warrant more focused attention at the WTO. These include the design of carbon pricing policies at the border that are transparent, fair and support a just transition; proposals for a climate waiver for WTO rules; and identification of ways multilateral trade cooperation could promote a zero carbon and more circular global economy. To help nudge multilateral discussion along, the UK could also ask to join a critical ‘path finder’ effort by six governments, led by New Zealand, to pursue an agreement on climate change, trade and sustainability (ACCTS). This group aims to find ways forward on three central trade and climate issues: removing fossil fuel subsidies, climate-related labelling, and promoting trade in climate-friendly goods and services.At present, the complex challenges at the intersection of climate, trade and development policy are too often used to defer or side-step issues deemed ‘too hard’ or ‘too sensitive’ to tackle. The UK could help here by working to ensure multilateral climate and trade initiatives share adjustment burdens, recognise the historical responsibility of developed countries, and do not unfairly disadvantage developing countries - especially the least developed.Many developing countries are keen to promote climate-friendly exports as part of wider export diversification strategies and want to reap greater returns from greener global value chains. Further, small island states and least-developed countries – many of which are Commonwealth members – that are especially vulnerable to the impacts of climate change and natural disasters, need support to adapt in the face of trade shocks and to build climate-resilient, trade-related infrastructure and export sectors.As an immediate next step, the UK should actively support the growing number of WTO members in favour of a WTO Ministerial Statement on environmental sustainability and trade. It should work with its key trading partners in the Commonwealth and beyond to ensure the agenda is inclusive, supports achievement of the UN Sustainable Development Goals (SDGs) and helps developing countries benefit from a more environmentally sustainable global economy.As the UK prepares to host COP26, negotiates deals with the EU and US, and prepares for its first WTO Ministerial meeting as an independent member, it must show it can lead the way nationally, bilaterally, and multilaterally. And to ensure the government acts, greater engagement from the UK’s business, civil society and research sectors is critical – we need all hands on deck to forge and promote concrete proposals for aligning UK trade policy with the climate ambition our world needs. Full Article
bal Brain manganese and the balance between essential roles and neurotoxicity [Molecular Bases of Disease] By feedproxy.google.com Published On :: 2020-05-08T03:41:14-07:00 Manganese (Mn) is an essential micronutrient required for the normal development of many organs, including the brain. Although its roles as a cofactor in several enzymes and in maintaining optimal physiology are well-known, the overall biological functions of Mn are rather poorly understood. Alterations in body Mn status are associated with altered neuronal physiology and cognition in humans, and either overexposure or (more rarely) insufficiency can cause neurological dysfunction. The resultant balancing act can be viewed as a hormetic U-shaped relationship for biological Mn status and optimal brain health, with changes in the brain leading to physiological effects throughout the body and vice versa. This review discusses Mn homeostasis, biomarkers, molecular mechanisms of cellular transport, and neuropathological changes associated with disruptions of Mn homeostasis, especially in its excess, and identifies gaps in our understanding of the molecular and biochemical mechanisms underlying Mn homeostasis and neurotoxicity. Full Article
bal NAD+ biosynthesis in bacteria is controlled by global carbon/nitrogen levels via PII signaling [Microbiology] By feedproxy.google.com Published On :: 2020-05-01T00:06:09-07:00 NAD+ is a central metabolite participating in core metabolic redox reactions. The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+. Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln. Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell. Here, using affinity chromatography, bioinformatics analyses, NAD synthetase activity, and biolayer interferometry assays, we show that PII and NadEGln physically interact in vitro, that this complex relieves NadEGln negative feedback inhibition by NAD+. This mechanism is conserved in distantly related bacteria. Of note, the PII protein allosteric effector and cellular nitrogen level indicator 2-oxoglutarate (2-OG) inhibited the formation of the PII-NadEGln complex within a physiological range. These results indicate an interplay between the levels of ATP, ADP, 2-OG, PII-sensed glutamine, and NAD+, representing a metabolic hub that may balance the levels of core nitrogen and carbon metabolites. Our findings support the notion that PII proteins act as a dissociable regulatory subunit of NadEGln, thereby enabling the control of NAD+ biosynthesis according to the nutritional status of the bacterial cell. Full Article
bal Global Speaker Line-up for The London Conference 2015 By feedproxy.google.com Published On :: Wed, 08 Jul 2015 15:55:58 +0000 21 May 2015 Chatham House is pleased to announce the speaker line-up for its second annual London Conference, at Lancaster House on 1-2 June 2015. 20140521ShardLondon.jpg Photo by Sean Randall/Getty Images. Chatham House’s annual London Conference looks at the big issues that confront the world at this key moment in history, and at how to design the new systems and institutions that will shape the international landscape of the future.Speaker highlights Fernando Henrique Cardoso, President of Brazil (1995-03)Kevin Rudd, President, Asia Society Policy Institute; Prime Minister of Australia (2013; 2007-10)Yannis Stournaras, Governor, Bank of Greece; Minister of Finance, Greece (2012-14) Børge Brende, Minister of Foreign Affairs, Norway Sergey Karaganov, Foreign policy adviser to the Presidential Administration, Russia (2001-13) Anders Fogh Rasmussen, Secretary General, NATO (2009-14); Prime Minister of Denmark (2001-09) Dr Barham Ahmed Salih, Prime Minister of Iraqi Kurdistan (2009-12); Deputy Prime Minister of Iraq (2006-09) This year's London Conference takes places ahead of the G7 summit in Germany. The themes – demographic changes, urbanization, technological disruptions and resource constraints – are woven throughout the sessions. The aim is not only to discuss the major challenges that these issues present, but also ‘how’ and ‘by whom’ they should be addressed.Panel discussions will include The Changing Geopolitical Context: Reassessing Priorities and Approaches - In conversation with Kevin Rudd and Fernando Henrique Cardoso What are the implications of the United States substantially retreating from its global leadership role? How are new patterns and habits of digital connectivity changing relations between governments and their populations? Can countries count on technological advances to deliver new routes to economic growth and social inclusion? Is it more important to build national, regional or sectoral successes than to expect answers at the level of global governance?Click here for full list of speakers >Click here for full conference agenda > Editor's notes Journalists are asked to email pressoffice@chathamhouse.org if they wish to apply for press accreditation. This conference will be livestreamed on the Chatham House website.The conference is sponsored by Chevron, AIG, BP, Bloomberg and Diageo and has the support of the UK Foreign and Commonwealth Office.The recommended hashtag for this event will be #LondonConference Contacts Press Office +44 (0)20 7957 5739 Email Full Article
bal Global health system needs reform to help deliver SDGs, says new report By feedproxy.google.com Published On :: Fri, 09 Oct 2015 14:31:11 +0000 24 September 2015 20150922RethinkingGlobalHealthArchitecture.jpg A Pakistani health worker gives polio vaccines to children in the suburbs of Lahore, Pakistan, February 2015. Photo: Associated Press. The global health system has contributed significantly to improved health and life expectancy in recent decades. However, the existing architecture needs to be reformed in order to address future challenges and meet the health targets in the Sustainable Development Goals. Rethinking the Global Health System, a new Chatham House report, analyses how fit for purpose the current system is and identifies priority areas for reform. The Ebola crisis has shown that weak systems make individual countries more vulnerable and that strong, resilient and equitable systems at country level are needed to protect global health security. There is a pressing need for enhanced global disease surveillance and detection capacity, as well as improved international coordination in responding to emerging health threats.In addition, addressing determinants of health outside the health sector requires cross-sectoral collaboration and linkages to other policy domains. Historically, the focus has rested on directly reducing illness and death, but the need to address other influences on health outcomes – safe drinking water, proper sewage treatment, good education – is now well recognized.The report says that stronger leadership in global health is therefore required and the report lends support to calls for the creation of a new organization that would bring together United Nations agencies with health-related mandates – UN-HEALTH. Just as UNAIDS created a more coherent response for HIV, a UN-HEALTH organization could achieve a similar but more wide-reaching effect by bringing together and streamlining all UN agencies working on global health issues.Professor David Harper, who led the Chatham House project that resulted in the report, said: 'This report is intended to make a substantial contribution to the international debate on what the world will require of the health architecture of the future. It offers some options for political leaders to consider, but it is just a starting point. More work is urgently needed to develop the ideas introduced in this project and to help generate the high-level political traction that is so vital in any change process.' Editor's notes Read the report Rethinking the Global Health System from the Centre on Global Health Security at Chatham House. For all enquiries, including requests to speak with the authors of this paper, please contact the press office. Contacts Press Office +44 (0)20 7957 5739 Email Full Article