20user guide

Extending across seven provinces and two autonomous regions, the Yellow River Ecological Corridor (YREC) comprises the second largest river basin in the People's Republic of China (PRC) with a population of 120 million. The basin is critical for food security yet faces complex ecological and environmental challenges. The region suffers from severe water scarcity, impacts from climate change and environmentally unsustainable development.

The project will continue the support of the Asian Development Bank (ADB) to Bangladesh in managing the influx of around one million displaced people from Myanmar (DPFM) since 2017. Now a protracted situation, the crisis is putting significant pressure on infrastructure and causing substantial challenges in terms of food, shelter, health, security, water, sanitation, and other services in the DPFM camps and host communities.

The project will be aligned with the following impacts: (i) modern public health service system ensuring well-being of all Thais in an effective, fair, sufficient, and sustainable manner developed; and (ii) UHC, including access to essential health care services, sustained. The outcome is: access to quality public hospital services by all in selected provinces improved.

The project will build and equip 3 climate-resilient and energy-efficient border crossing points (BCP) between the Kyrgyz Republic and Kazakhstan on the Kyrgyz side of the border and a training center for the Kyrgyz Border Service (the project EA). The project with the total loan and grant financing of $37 Million will help facilitate trade and tourism between the Kyrgyz Republic and Kazakhstan and will contribute to the sustainable economic development along the Almaty-Bishkek Economic Corridor.

The project will support Ho Chi Minh City People's Committee and their government to finance sound wastewater and drainage system in the remaining catchments, thereby strengthening its foundation as the socioeconomic growth pole of southern Viet Nam. The impact of the project will be improved surface water quality and drainage capacity in HCMC. The outcome will be increased wastewater and drainage collection and treatment capacity in key catchments in HCMC.

Project objectives. The proposed project will assist the government in addressing climate vulnerabilities and enhancing public health and economic conditions by ensuring inclusive access to safe, reliable, climate-resilient, and sustainable WSS services for the residents of Andijan, Djizzak and Fergana provinces; and the Republic of Karakalpakstan. The project will help upgrade and expand the WSS infrastructure in the project regions and support regional suvtaminots in implementing transformational changes.

The largest pterosaurs, ancient reptiles that were the first vertebrates to master flight, may have mostly soared while smaller ones flapped their wings, a pattern that persists in today's birds

Unravelling the complex biological process that allows fish to regrow injured fins could help advance regenerative medicine in humans

Kew scientists use paramotorists to collect rare plant species from Peruvian desert oases

Not all winged dinosaurs were necessarily capable of full flight, but this anatomical feature may have enabled them to travel further by flapping or gliding

One hundred years ago, we discovered there were other galaxies beyond our own. Now, we might be on the verge of another discovery: that there are other universes

Ultra-fast pulses of laser light can be shaped into vortices similar to smoke rings – when chained together, they can carry enough information to transmit a simple image

The Linac Coherent Light Source in California fired an X-ray pulse that lasted only a few hundred billionths of a billionth of a second but carried nearly a terawatt of power

One hundred years ago, we discovered there were other galaxies beyond our own. Now, we might be on the verge of another discovery: that there are other universes

Researchers have reshaped single electrons into spiralling matter waves with distinct handedness that could be used to study and control materials

Geologists think there may be vast natural stores of hidden hydrogen gas within Earth, but no one is sure how much there is or how much could be recovered for energy

An analysis of satellite observations has identified some extreme thunderstorms over the Indian Ocean and Gulf of Mexico with lightning flashes so frequent that the sky would appear continuously lit

Endurance sank beneath the ice during Ernest Shackleton’s legendary Antarctic expedition. More than a hundred years later, researchers document their own saga of how they found the vessel

Endurance sank beneath the ice during Ernest Shackleton’s legendary Antarctic expedition. More than a hundred years later, researchers document their own saga of how they found the vessel

Intact human brains 12,000 years old or more have been found in unexpected places such as shipwrecks and waterlogged graves, but it is unclear what preserved them

A settlement in the east of England burned down in a fire 3000 years ago, falling into a muddy waterway that preserved everything inside the houses including tools, fabric, cooking pots and more

Underground tunnels created by lava flows provided humans with shelter for thousands of years beneath the hot desert landscape of Saudi Arabia

Archaeologists have used AI to discover hundreds of large-scale drawings depicting figures like llamas, decapitated human heads and killer whales armed with knives

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Category: Health News
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Category: Health News
Created: 8/23/2021 12:00:00 AM
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Category: Health News
Created: 8/24/2021 12:00:00 AM
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Category: Health News
Created: 8/17/2022 12:00:00 AM
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Category: Diseases and Conditions
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Last Editorial Review: 7/5/2022 12:00:00 AM

Extract

Living with a respiratory illness requires patients to manage a wide range of symptoms, many of which will worsen as a disease progresses. Breathlessness is a hallmark feature of respiratory conditions, occurring in almost all individuals with COPD and interstitial lung disease (ILD) [1, 2]. Cough is present in 78% of people with ILD and is frequently distressing, with physical, social and emotional impacts [1, 3].

Extract

We read with great interest the review article by Randerath et al. [1] recently published in the European Respiratory Review. We would like to congratulate the authors on this clearly structured review, which emphasises the urgent need for an increasingly differentiated view of central sleep apnoea (CSA) in the context of precision medicine.

Background

People living with serious respiratory illness experience a high burden of symptoms. This review aimed to determine whether multicomponent services reduce symptoms in people with serious illness related to respiratory disease.

Background

In adults with serious respiratory illness, fatigue is prevalent and under-recognised, with few treatment options. The aim of this review was to assess the impact of graded exercise therapy (GET) on fatigue in adults with serious respiratory illness.

Background

In adults with serious respiratory illness, breathlessness is prevalent and associated with reduced health-related quality of life. The aim of this review was to assess the impact of breathing techniques on breathlessness in adults with serious respiratory illness.

Background

People living with serious respiratory illness experience a high burden of distressing symptoms. Although opioids are prescribed for symptom management, they generate adverse events, and their benefits are unclear.

Purpose Low-income children experience disproportionately high rates of dental caries and challenges in accessing dental care compared to their higher-income peers. The purpose of this scoping review was to examine the prevalence of dental caries and dental service utilization among Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) enrolled children.Methods The literature search and review were conducted between September 2023 and February 2024. The review followed the PRISMA-ScR reporting guidelines and included three databases: PubMed, CINAHL, and Dentistry & Oral Sciences Source. The study focused on children aged one to five participating in WIC within the United States (US) and aimed to determine the prevalence of dental service utilization and dental caries in the targeted population.Results This review includes twelve articles that are quantitative observational studies conducted from February 2001 to February 2023. Most of the studies were conducted in WIC programs in the Southern and Midwest regions of the US. Dental caries rates decreased by 61.8% from 2004 to 2016, with the highest prevalence in 2004, and the lowest prevalence in 2016. Dental service utilization among WIC children increased by 56.9% from 1992 to 2020.Conclusion There has been an increase in dental service utilization among WIC-enrolled children, with an overall decrease in dental caries over the last two decades. However, the prevalence of dental caries remains disproportionately high for children enrolled in WIC when compared to non-participants. To develop effective dental interventions for children enrolled in WIC, it is fundamental to identify the unique determinants of dental caries in this population.

A STING (stimulator of interferon genes) agonist GSK3996915 under investigation in early discovery for hepatitis B was orally dosed to a mouse model for understanding the parent drug distribution in liver, the target organ. Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) was used to quantify the distribution of GSK3996915 in liver collected from mice administered a single oral dose at 90 mg/kg. GSK3996915 was detected with a zonal distribution localized in the portal triad and highly concentrated in the main bile ducts, indicating clearance through biliary excretion. High spatial resolution imaging showed the distribution of the parent drug localized to the cellular populations in the sinusoids, including the Kupffer cells. Additionally, a series of drug-related metabolites were observed to be localized in the central zones of the liver. These results exemplify the potential of utilizing MALDI IMS for measuring not only quantitative drug distribution and target exposure but also drug metabolism and elimination in a single suite of experiments.

ABSTRACTIntroduction:Since the health information system (HIS) in public health care services in Serbia was introduced in 2009, it has gradually expanded. However, it is unclear how well the HIS components have developed and the whole system’s stage of maturity.Method:In June–September 2021, a maturity assessment of the Serbian HIS was conducted for the first time using the HIS Stages of Continuous Improvement (SOCI) toolkit. The toolkit measures HIS status across 5 HIS domains: leadership and governance, management and workforce, information and communication technology (ICT), standards and interoperability, and data quality and use. The domains were further divided into 13 components and 39 subcomponents whose maturity stage was assessed on a 5-point Likert scale, indicating the level of development: (1) emerging/ad hoc; (2) repeatable; (3) defined; (4) managed; and (5) optimized. The toolkit was applied in a working group of 32 professionals and experts who were engaged in developing the new national eHealth strategy and action plan.Results:The overall maturity score of the Serbian HIS was 1.6, which indicates a low level. The highest baseline score (2) was given to the standards and interoperability domain, and the lowest (1.1) was given to ICT infrastructure. The remaining 3 domains (leadership and governance, Management and Workforce, and Data Quality and Use) were similarly rated (1.7, 1.7, and 1.6, respectively).Conclusion:A baseline assessment of the maturity level of Serbian HIS indicates that the majority of components are between the emerging/ad hoc stage and repeatable, which represent isolated, ad hoc efforts, with some basic processes in place and existing and accessible policies. This exercise provided an opportunity to address identified weaknesses in the upcoming national eHealth strategy.