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Treating Geriatric Polypharmacy by Deintensifying Unnecessary Diabetes Treatment

Polypharmacy is a rapidly worsening problem that hits elderly patients particularly hard.  As patients grow older, they need more medications but at the same time become less capable of managing the complexity of drug treatments.  In order to simplify treatment regimens for older patients, it is necessary to consider the evidence supporting treatment of various conditions and when the evidence is not particularly strong, reduce or eliminate medications accordingly.  Diabetes management in the elderly is highlighted in this podcast with specific attention given to deintensifying diabetes treatment in the elderly.

Articles discussed in this episode:




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The High Cost of Pharmaceuticals in the United States

Drug prices continue to rise in the US. Many solutions have been proposed but few have been implemented. Drs. Janet Woodcock from the FDA and Aaron Kesselheim, author of The High Cost of Prescription Drugs in the United States from the Harvard Medical School discuss the role of brand name drugs and generics and how they influence the cost of pharmaceuticals.

Also see The Cost of US Pharmaceutical Price Reductions: A Financial Simulation Model of R&D Decisions by Thomas A. Abbott and John A. Vernon.




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Managing energy, nutrients, and pests in organic field crops / edited by Ralph C. Martin and Rod MacRae




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Genomics in aquaculture / edited by Simon MacKenzie, Sissel Jentoft, Department of Natural Sciences

Mackenzie, Simon




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The status of kangaroos and wallabies in Australia / report of a Working Group on Macropod Habitat of the Standing Committee of the Council of Nature Conservation Ministers ; edited by Dr. A.A. Burbidge

Council of Nature Conservation Ministers (Australia). Working Group on Macropod Habitat




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Engineering salinity solutions : 1st National Salinity Engineering Conference 2004 conference proceedings : 9-12 November 2004, Burswood International Resort, Perth, Western Australia / Engineers Australia; edited by Shawan Dogramaci, Alex Waterhouse

National Salinity Engineering Conference (1st : 2004 : Perth, W.A.)




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[ASAP] Lithium Ion Conduction in Cathode Coating Materials from On-the-Fly Machine Learning

Chemistry of Materials
DOI: 10.1021/acs.chemmater.9b04663




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[ASAP] Toward Designing Highly Conductive Polymer Electrolytes by Machine Learning Assisted Coarse-Grained Molecular Dynamics

Chemistry of Materials
DOI: 10.1021/acs.chemmater.9b04830




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Space stations: the art, science, and reality of working in space / Dr. Gary Kitmacher, Ron Miller, Robert Pearlman ; foreword, Nicole Stott

Hayden Library - TL797.K5745 2018




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Handbook of Satellite Applications edited by Joseph N. Pelton, Scott Madry, Sergio Camacho-Lara

Online Resource




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Handbook of space pharmaceuticals / editors, Yashwant Pathak, Marlise Araújo dos Santos, Luis Zea

Online Resource




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Escape from Earth: a secret history of the space rocket / Fraseer MacDonald

Hayden Library - TL781.8.U5 M23 2019




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Unmanning: how humans, machines, and media perform drone warfare / Katherine Chandler

Dewey Library - UG1242.D7 C435 2020




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Modern architecture Kuwait: 1949-1989 / Fabbri Roberto, Sara Saragoça, Ricardo Camacho ; Arabic translation: Mohamed M. Moustafa

Rotch Library - NA1472.5.F33 2016




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The Ottomans and the Mamluks: imperial diplomacy and warfare in the Islamic world / Cihan Yüksel Muslu

Rotch Library - DS38.7.M865 2014




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Practising diplomacy in the Mamluk Sultanate: gifts and material culture in the medieval Islamic world / Doris Behrens-Abouseif

Rotch Library - DT96.B447 2016




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Arabic type-making in the machine age: the influence of technology on the form of Arabic type, 1908-1993 / by Titus Nemeth

Rotch Library - Z251.A6 N46 2017




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Political change in the Middle East and North Africa: after the Arab Spring / edited by Inmaculada Szmolka

Rotch Library - JQ1850.A91 P65 2017




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The progressive revolution: modern art for a new India / Zehra Jumabhoy and Boon Hui Tan ; with additional contributions by Amal Allana, Yashodhara Dalmia, Faisal Devji, Conor Macklin, and Gayatri Sinha

Rotch Library - N7304.5.P76 J86 2018




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Arabs: a 3,000-year history of peoples, tribes and empires / Tim Mackintosh-Smith

Rotch Library - DS218.M33 2019




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Çemberlitaș Hamami in Istanbul: the biographical memoir of a Turkish bath / Nina Macaraig

Rotch Library - GT2846.T9 M33 2018




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Mamluk Cairo, a crossroads for embassies: studies on diplomacy and diplomatics / edited by Frédéric Bauden, Malika Dekkiche

Rotch Library - DT96.M21535 2019




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The making of Selim: succession, legitimacy, and memory in the early modern Ottoman world / H. Erdem Cipa

Rotch Library - DR504.C56 2017




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HUL eyes bigger market with VWash, seeks larger presence in pharmacies

On Monday, the company announced it was buying VWash, an intimate hygiene brand from Glenmark Pharmaceuticals




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Ian Watt : the novel and the wartime critic / Marina MacKay

MacKay, Marina, 1975- author




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[ASAP] A Perspective on Continuous Flow Chemistry in the Pharmaceutical Industry

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00524




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[ASAP] Recent Progress in Continuous Crystallization of Pharmaceutical Products: Precise Preparation and Control

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00362




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[ASAP] Continuous Flow Conditions for High Temperature Formation of a Benzodioxan Pharmaceutical Intermediate: Rapid Scaleup for Early Phase Material Delivery

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00499




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[ASAP] Green Chemistry Articles of Interest to the Pharmaceutical Industry

Organic Process Research & Development
DOI: 10.1021/acs.oprd.0c00154




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[ASAP] Improved Synthesis of 6-Chloro-5-methylpyridin-2-amine: A Key Intermediate for Making Lumacaftor

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00556




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The boy, the mole, the fox and the horse / Charlie Mackesy

Barker Library - PN6737.M35 B69 2019




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American Gods: shadows / story and words by Neil Gaiman ; script and layouts by P. Craig Russell ; art by Scott Hampton ; letters by Rick Parker ; cover by David Mack

Barker Library - PN6728.A482 R87 2018




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Strategic reconstruction of macrophage-derived extracellular vesicles as a magnetic resonance imaging contrast agent

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00128G, Paper
Sagar Rayamajhi, Ramesh Marasini, Tuyen Duong Thanh Nguyen, Brandon L. Plattner, David Biller, Santosh Aryal
Reconstruction of extracellular vesicles with imaging agents allows precise downstream analysis using clinical imaging modalities, for example, MRI. This will further improve the biocompatibility of agents thereby enhancing clinical investigations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00147C, Paper
Open Access
Junxiong Qiu, Peng Peng, Min Xin, Zhenkang Wen, Zhong Chen, Sipeng Lin, Manyuan Kuang, Yuan Fu, Guibin Fang, Shixun Li, Changchuan Li, Jiaji Mao, Ling Qin, Yue Ding
Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide

Toxicol. Res., 2019, 8,850-861
DOI: 10.1039/C9TX00067D, Paper
Wei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
Integrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Nanosphere-shaped ammonio methacrylate copolymers: converting a pharmaceutical inactive ingredient to efficient therapeutics for experimental colitis

Nanoscale, 2020, 12,9590-9602
DOI: 10.1039/D0NR00465K, Paper
Brice Moulari, Maryam A. Shetab Boushehri, Jean-Paul Pais de Barros, Thilo Faber, Arnaud Béduneau, Laurent Lagrost, Yann Pellequer, Alf Lamprecht
Even in the absence of any drug load, nanosphere-shaped ammonio methacrylate copolymers can mitigate murine experimental colitis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bad Neighbour, Good Neighbour: How Magnetic Dipole Interactions Between Soft and Hard Ferrimagnetic Nanoparticles Affect Macroscopic Magnetic Properties in Ferrofluids

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02023K, Paper
Niéli Daffé, Jovana Zecevic, Kalliopi Trohidou, Marcin Sikora, Mauro Rovezzi, Claire Carvallo, Marianna Vasilakaki, Sophie Neveu, Johannes D. Meeldijk, Nadejda Bouldi, Veronica Gavrilov, Yohan Guyodo, Fadi Choueikani, Vincent Dupuis, Dario Taverna, Philippe Sainctavit, Amélie JUHIN
Fluids responding to magnetic fields (ferrofluids) offer a scene with no equivalent in nature to explore long-range magnetic dipole interactions. Here, we studied the very original class of binary ferrofluids,...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pharmacist's hobby becomes a museum




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Dan MaCarty's is "a living monument"




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Información hidrométrica del caudal Cuecha en Monteverde, febrero-marzo 2002




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Del Lic. José Manuel Echandi, Defensor de los Habitantes, para el Ing. Sergio Salas Arias, gerente general, Servicio Nacional de Aguas Subterraneas Riego y Avenamiento. Solicitud de ampliación de información a Ing. Sergio Salas Arias (SENAR




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Del Lic. José Manuel Echandi, Defensor de los Habitantes, para el Lic. Randall Quirós Bustamante, ministro, MOPT. Solicitud de ampliación de información a M.O.P.T., 1-3-05




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De Xenia González Rojas, vecina Los LLanos, para Victorino Molina Rojas, presidente, Junta Directiva, Asociación Acueductos Rurales. Solicitud de información sobre razones de falta de agua en Monteverde




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The effects of pollution on benthic macroinvertebrate community structure and composition




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Del Licenciado José Manuel Echandi, Defensoria de los Habitantes, para el Licenciado Randall Quiros Bustamante, Ministerio de Obras Públicas y Transportes. Solicitud de Ampliación de Información




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Estudio para determinar el volumen del tanque de almacenamiento a Construir en el sector Cañitas




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Estudio para determinar el volumen del tanque de almacenamiento a construir en el sector de los Llanos




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The effects of human-caused disturbances on water quality and the capability of river ecosystems to recover from disturbances : using benthic macroinvertebrates as indicators of water quality




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There and where again : a watershed's tale : use of macroinvertebrate indicators in the Río Guacimal Watershed to indicate changes in water conditions over time and present anthropogenic impact




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Estudio para determinar el volumen del tanque de almacenamiento para el acueducto de Santa Elena de Monteverde (tanque Juan Delfín)