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Chemistry breakthrough could speed up drug development

Scientists have successfully developed a new technique to reliably grow crystals of organic soluble molecules from nanoscale droplets, unlocking the potential of accelerated new drug development.




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Perspective: Rapid COVID-19 vaccine development

When seeking the fastest pathway to a vaccine to prevent coronavirus disease 19 (COVID-19), defining the stakes and potential hurdles is critical, says Barney Graham in this Perspective.




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'Detailed' plans being drawn up to restart economy, Jenrick says as testing falls below 100,000 for fourth day

The update comes after Prime Minister Boris Johnson confirmed he would set out a lockdown exit strategy on Sunday.




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Tesla chief Elon Musk set for £600m payday after targets reached

He will receive nearly 1.69 million stock options priced at 350.02 dollars (£285).




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COVID-19 took my beloved mother, but in every way she is greater than this virus

There's a thought that really distresses me as I grieve for my 87-year-old mother.




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US oil price falls below $0 for first time

The benchmark price for US crude plummeted to negative $US35.20 a barrel as traders sought to avoid owning crude with nowhere to store it.




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Spirit of Tasmania to move Victorian operations to Geelong

The company behind the Spirit of Tasmania ferry service says its ships will no longer be docking at Station Pier in Port Melbourne, and will instead move to Corio Quay, north of Geelong.




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Australia's tallest building to be built in Melbourne as Government fast-tracks development

The Victorian Government announces a proposal for a 101-storey building is one of four to be approved amid moves to fast-track development in the wake of the coronavirus pandemic.



  • Business
  • Economics and Finance
  • Urban Development and Planning
  • Government and Politics
  • Building and Construction
  • States and Territories
  • Architecture

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Tesla shares tumble after Elon Musk tweets they're too expensive

Elon Musk has seen Tesla's share price falling after a series of unusual tweets, including saying he would sell all his possessions.



  • Business
  • Economics and Finance
  • Science and Technology
  • COVID-19
  • Diseases and Disorders

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We Now Know How To Pronounce Elon Musk's Son's Name & It's (X Æ A-)12 Different Types Of Weird




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India develops unique model to hit enemy targets without positioning error

New Delhi (Sputnik) Apr 22, 2020
Due to the unavailability of a reliable model to predict the electron density of the ionosphere, navigation errors remain, creating technological hurdles. A new model developed by Indian researchers has potential applications in calculating these Global Navigation Satellite System (GNSS) positioning errors. In a major development that could have a wider impact, ranging from accurate aiming




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Elon Musk bought properties around him because people climbed walls to break in - now he's selling them all

Billionaire and new dad Elon Musk has opened up about the alarming "privacy issues" that sparked his property-buying bonanza.The Tesla and SpaceX founder, who has just welcomed his sixth child, was interviewed by comedian Joe Rogan...




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[EN DIRECT 9 MAI] Tous les développements de la pandémie

Que ce soit au Québec ou ailleurs sur la planète, la pandémie de COVID-19 a bouleversé nos vies.





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NIH 'Shark Tank' to Develop Faster, Cheaper, More Reliable COVID-19 Tests

(MedPage Today) -- WASHINGTON -- Millions more coronavirus tests are needed to curb the spread of the virus and guide decisions around safely reopening businesses and schools, Sen. Lamar Alexander (R-Tenn.), chair of the Senate Health, Education...




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Geelong coach Chris Scott defends AFL players amid pay cut negotiations

AFL players have been accused of being greedy and selfish during talks with the league over pay cuts now that the season is suspended, but the Cats coach says it is unfair.




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LaMelo Ball in talks to buy Hawks after breakout NBL season

He came, he produced a jaw-dropping highlights reel, he got injured, he left without saying goodbye, and now the Californian NBA prospect apparently returns with a consortium in tow to buy the Illawarra Hawks.




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Grimes explains her baby's outlandish name — and Elon Musk corrects her

"I am recovering from surgery and barely alive so may my typos b forgiven," Grimes replied to boyfriend Elon Musk after tweeting the inspiration for baby name X Æ A-12.




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Comedy Central, BET, Nickelodeon coming to YouTube TV

ViacomCBS' first-quarter earnings beat expectations, leading to a stock rally.




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Even Elon Musk and Grimes can't decide how to pronounce their baby's name

Is the "Æ" in the name X Æ A-12 pronounced "A-I" or "ash"? Depends on which parent (Elon Musk or Grimes) you ask.




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$8-billion effort aims to speed development of coronavirus vaccines and treatments

The World Health Organization joined with global leaders to accelerate production of vaccines and treatments aimed at stamping out the coronavirus.




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NIAB develops portable 'ECovSens' tool for diagnosis of COVID─19 antigens from saliva




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Union health minister calls upon all scientific depts to develop enhanced synergy for better results




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Allmpus Labs to focus on increasing R&D in new drug discovery and development




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Teknor Apex develops new series of TPEs

Advanced chemistry developed by Teknor Apex has yielded a new series of ThermoPlastic Elastomers (TPEs) for over-moulding that exhibit adhesion to engineering plastic substrates while meeting the requirements for use in medical devices.




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Scientists are developing an anti-coronavirus surface coating based on nanomaterials

The research by Ben-Gurion University (BGU) and the National Institute of Biotechnology in the Negev (NIBN), has received financial support from the Israel Innovation Authority as part of a call for proposals for coping with the coronavirus.




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Newron drops development of sarizotan in Rett syndrome

The experimental 5-HT1A receptor agonist and D2 receptor antagonist was not effective on primary or secondary endpoints




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Dr Maritza McIntyre appointed Chief Development Officer at StrideBio

StrideBio have announced the appointment of Maritza McIntyre Ph.D., as its first Chief Development Officer.

The newly created role will see Dr McIntyre oversea the translational development of the company’s research-stage gene therapy programs. This includes regulatory filings, initiating early clinical studies and starting Investigational New Drug enabling preclinical studies.

read more




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New UK taskforce to help develop and roll out coronavirus vaccine

Government bodies, industry and charities to collaborate in research efforts

The government has announced a new vaccines taskforce to help the development of a vaccine for Covid-19 and ensure its rapid production and rollout if one arrives.

The business secretary, Alok Sharma, also gave details of cash grants for work into both vaccines and potential treatments. Among the projects receiving cash is one led by Public Health England (PHE), which hopes to develop an antibody drug, something that has the potential to work as both a prophylactic and a treatment for those infected.

Related: The hunt for a coronavirus vaccine

Hydroxychloroquine, also known by its brand name, Plaquenil, is a drug used to treat malaria. It is a less toxic version of chloroquine, another malaria drug, which itself is related to quinine, an ingredient in tonic water.

Continue reading...




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AstraZeneca joins forces with University of Oxford to develop and manufacture potential coronavirus vaccine

A “landmark” partnership has been struck between AstraZeneca and the University of Oxford in the ongoing battle against COVID-19, with the former agreeing to aid in the development and large-scale manufacture of the latter’s potential recombinant adenovirus vaccine for the prevention of novel coronavirus infection.



  • Research and Development
  • Manufacturing and Production

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Firms ready RNAi candidate for COVID-19 development

A collaboration in COVID-19 between immunology specialist Vir Biotechnology and Alnylam Pharmaceuticals…



  • Alnylam Pharmaceuticals/Anti-virals/Biotechnology/Cell and Gene Therapy/Coronavirus/Focus On/Public health/Research/USA/Vir Biotechnology/VIR-2703

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Justice Department Sues Large Multi-Family Housing Developer Alleging Disability-Based Housing Discrimination

The Department filed a lawsuit today against JPI Construction L.P. (JPI) and six JPI-affiliated companies in U.S. District Court in Dallas for failing to provide accessible features required by the Fair Housing Act and the Americans with Disabilities Act at multi-family housing developments in Texas and other states.



  • OPA Press Releases

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60th Felony Conviction Obtained in Software Piracy Crackdown “Operation Fastlink”

The 60th felony conviction from Operation Fastlink, a major Department of Justice initiative to combat online piracy worldwide. Bryan Thomas Black, 30, of Waterloo, Ill., pleaded guilty today to one count of conspiracy to commit criminal infringement of a copyright for his involvement in a multinational software piracy organization that was targeted by investigators as part of “Operation Fastlink,” an internationally coordinated 18-month investigation.



  • OPA Press Releases

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Attorney General Eric Holder at the Semi-Annual Conference of the Office of Overseas Prosecutorial Development Assistance and Training (OPDAT) Resident Legal Advisors and Foreign Service Nationals

"Helping foreign countries improve their criminal justice systems so they can cooperate more effectively with us and with their neighbors in real time is an important aspect of this department’s mission."




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Justice Department Files Complaint and Reaches Settlement to Improve Conditions at Texas State Facilities for Persons with Developmental Disabilities

The Department announced a simultaneous lawsuit and settlement with the state of Texas concerning the care given to residents of the state’s 13 facilities for persons with developmental disabilities. Along with the settlement agreement, the Department will file a complaint initiating a lawsuit against the state in federal court. An independent monitor will be appointed to oversee the state’s compliance with the settlement agreement and the court will retain ultimate jurisdiction.



  • OPA Press Releases

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Justice Department Announces Disabled Access Settlement with Developers of Woodbridge, Virginia, Apartment Complex

The Justice Department today announced a settlement that, pending court approval, will resolve allegations that those involved in the design and construction of the Summerland Heights Apartments, a 318-unit apartment complex in Woodbridge, Va., discriminated on the basis of disability in the design and construction of the project.



  • OPA Press Releases

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Home Development Company Agrees to Settle Federal Lawsuit for Clean Water Act Violations

Cooper Land Development, Inc., a luxury home development company headquartered in Rogers, Ark., has agreed to pay a civil penalty and implement a storm water compliance program at its construction sites to settle allegations that it violated the Clean Water Act.



  • OPA Press Releases

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Justice Department Files Lawsuit Alleging Disability-Based Housing Discrimination Against Idaho Condominium Developer

The Justice Department today filed a lawsuit against the developer of the Riverwalk Condominiums, a condominium apartment complex in Post Falls, Idaho, for violating the Fair Housing Act by constructing apartments that do not have required accessibility for individuals with disabilities.



  • OPA Press Releases

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California Court Permanently Enjoins Developer of the “Derivium” “90% Loan” Tax Scheme

The complex tax scheme involved numerous entities located around the globe and sales of over $1.25 billion in securities



  • OPA Press Releases

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KV Pharmaceutical Subsidiary Pleads Guilty to Two Felonies Regarding Oversized Drugs

Ethex Corporation, a wholly owned subsidiary of St. Louis-based drug manufacturer, KV Pharmaceutical Company, pleaded guilty to two felonies and was sentenced today in connection with the manufacturing of oversized prescription drug tablets.



  • OPA Press Releases

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Justice Department Files for Immediate Relief Regarding Conditions at Conway Human Development Center, in Conway, Arkansas

The department’s motion for preliminary injunction aims to prevent the segregation of children with developmental disabilities in dangerous conditions and to address accusations of imminent and serious threats to the safety of the facility’s more than 500 current residents.



  • OPA Press Releases

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Miami Beach Hotel Developers Charged with Conspiring to Defraud United States

Mauricio Cohen Assor and his son, Leon Cohen-Levy, each with residences in Miami Beach, Fla., have been charged in a criminal complaint with conspiring to defraud the United States.



  • OPA Press Releases

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Felon Who Impersonated a Police Officer Pleads Guilty in Danziger Bridge Case

David Ryder, a convicted felon who was dressed as a police officer on the day of a police-involved shooting on Sept. 4, 2005, in New Orleans, pleaded guilty today in federal court to lying to a federal agent and to illegally possessing a firearm.



  • OPA Press Releases

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Miami Beach Hotel Developers Indicted and Charged with Tax Fraud

Mauricio Cohen Assor and his son, Leon Cohen-Levy, each with residences in Miami Beach, Fla., have been charged with conspiring to defraud the United States and filing false tax returns.



  • OPA Press Releases

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Attorney General Holder Delivers Remarks at the Organisation for Economic Co-Operation and Development

"Only by working together, across borders and jurisdictions, can we ensure that the ideals set forth in the Anti-Bribery Convention more than a decade ago are realized today and in the future.  And only by working together will the promise of democracy be fulfilled, and will the rule of law be respected, across the globe," said Attorney General Holder.




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Justice Department Enters Settlement with Rainbow River Child Development Center on Care for Children with Diabetes

The Department of Justice and the Rainbow River Child Development Center of Hawthorne, Calif., have joined in a settlement agreement to assure that children with diabetes will receive appropriate care so that they may participate fully in the programs and activities at the center.



  • OPA Press Releases

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Justice Department Files Lawsuit Against Georgia-based Multi Family Housing Developer Alleging Discrimination

The Justice Department announced that it filed a lawsuit today against Post Properties Inc., Post Apartment Homes L.P. and Post GP Holdings Inc. in the U.S. District Court for the Northern District of Georgia for failing to provide accessible features required by the Fair Housing Act and the Americans with Disabilities Act at multi-family housing developments in six states.



  • OPA Press Releases

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Laurence Tribe, Senior Counselor for Access to Justice, Speaks at the American College of Trial Lawyers 2010 Annual Meeting

"It’s a special honor for me to address the American College of Trial Lawyers, and to share the stage today with such impressive and distinguished speakers as Justice Cromwell, Justice Kirby, Judge Sparks, and Professor Coffee."




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Justice Department Obtains Comprehensive Agreement Regarding the State of Georgia’s Mental Health and Developmental Disability System

The Justice Department today announced that it has entered into a comprehensive settlement agreement that will transform the state of Georgia’s mental health and developmental disability system and resolve a lawsuit the United States brought against the state.



  • OPA Press Releases

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Laurence Tribe, Senior Counselor for Access to Justice, Speaks at the Bronx Defenders Annual Gala Dinner

"I’m enormously pleased that we at the Justice Department are supporting your important work through the Office of Justice Programs and are thereby helping you expand the reach of the holistic community oriented model to defender agencies across the country through the Center for Holistic Defense."