A discussion, including the former United Nations Deputy High Commissioner for Refugees, examining the huge strains on the global protection system and how it can better respond to protracted refugee situations and other long-term displacement, focusing on the conclusions of the Transatlantic Council on Migration's recent meeting, Beyond Asylum: Rethinking Protection Policies to Meet Sharply Escalating Needs.

Raj Kamal Maurya, Yogesh Mani Tripathi.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 2, 345--369.

Abstract:
We consider estimation of the multicomponent stress-strength reliability under progressive Type II censoring under the assumption that stress and strength variables follow Burr XII distributions with a common shape parameter. Maximum likelihood estimates of the reliability are obtained along with asymptotic intervals when common shape parameter may be known or unknown. Bayes estimates are also derived under the squared error loss function using different approximation methods. Further, we obtain exact Bayes and uniformly minimum variance unbiased estimates of the reliability for the case common shape parameter is known. The highest posterior density intervals are also obtained. We perform Monte Carlo simulations to compare the performance of proposed estimates and present a discussion based on this study. Finally, two real data sets are analyzed for illustration purposes.

Chenlu Shi, Boxin Tang.

Source: Bernoulli, Volume 26, Number 1, 418--431.

Abstract:
Strong orthogonal arrays were recently introduced as a class of space-filling designs for computer experiments. The most attractive are those of strength three for their economical run sizes. Although the existence of strong orthogonal arrays of strength three has been completely characterized, the construction of these arrays has not been explored. In this paper, we provide a systematic and comprehensive study on the construction of these arrays, with the aim at better space-filling properties. Besides various characterizing results, three families of strength-three strong orthogonal arrays are presented. One of these families deserves special mention, as the arrays in this family enjoy almost all of the space-filling properties of strength-four strong orthogonal arrays, and do so with much more economical run sizes than the latter. The theory of maximal designs and their doubling constructions plays a crucial role in many of theoretical developments.

Guo-qiang Bi
Dec 15, 1998; 18:10464-10472
Articles

Nitric oxide (NO) is an important signaling molecule that fulfills diverse functional roles as a neurotransmitter or diffusible second messenger in the developing and adult CNS. Although the impact of NO on different behaviors such as movement, sleep, learning, and memory has been well documented, the identity of its molecular and cellular targets is still an area of ongoing investigation. Here, we identify a novel role for NO in strengthening inhibitory GABA_A receptor-mediated transmission in molecular layer interneurons of the mouse cerebellum. NO levels are elevated by the activity of neuronal NO synthase (nNOS) following Ca²⁺ entry through extrasynaptic NMDA-type ionotropic glutamate receptors (NMDARs). NO activates protein kinase G with the subsequent production of cGMP, which prompts the stimulation of NADPH oxidase and protein kinase C (PKC). The activation of PKC promotes the selective strengthening of α3-containing GABA_ARs synapses through a GABA receptor-associated protein-dependent mechanism. Given the widespread but cell type-specific expression of the NMDAR/nNOS complex in the mammalian brain, our data suggest that NMDARs may uniquely strengthen inhibitory GABAergic transmission in these cells through a novel NO-mediated pathway.

SIGNIFICANCE STATEMENT Long-term changes in the efficacy of GABAergic transmission is mediated by multiple presynaptic and postsynaptic mechanisms. A prominent pathway involves crosstalk between excitatory and inhibitory synapses whereby Ca²⁺-entering through postsynaptic NMDARs promotes the recruitment and strengthening of GABA_A receptor synapses via Ca²⁺/calmodulin-dependent protein kinase II. Although Ca²⁺ transport by NMDARs is also tightly coupled to nNOS activity and NO production, it has yet to be determined whether this pathway affects inhibitory synapses. Here, we show that activation of NMDARs trigger a NO-dependent pathway that strengthens inhibitory GABAergic synapses of cerebellar molecular layer interneurons. Given the widespread expression of NMDARs and nNOS in the mammalian brain, we speculate that NO control of GABAergic synapse efficacy may be more widespread than has been appreciated.

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

Moner, a third generation believer from Syria, worked as a Christian worker under the protection of a Muslim ambassador from Syria in communist Poland.

Name: Oliviana Tugui Home: Bucharest, Romania Born in: August 1984 Joined OM Ships: February 2013 Previous employment: Teacher’s Assistant and ESL/Spanish Teacher for Primary Students Current job on board: International Café team member

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

Through contemporary worship, the OM team seeks to create an atmosphere of worship in which the younger generation in Japan can experience God.

Validated questionnaires can improve the identification of psychosocial problems among children. The Strengths and Difficulties Questionnaire (SDQ) 3-4 is a promising option. However, no studies are available that examine the psychometric properties of the SDQ parent form 3-4.

The results of this study show that the SDQ 3-4 is a valid tool for the identification of psychosocial problems in preschool-aged children. (Read the full article)

Levels of daily physical activity in children are decreasing worldwide. This implies risk factors for cardiovascular and metabolic diseases.

Strength training makes children not only stronger but significantly increases their daily spontaneous physical activity outside the training intervention. (Read the full article)

Resistance exercise is known to have a robust effect on glycemic control and cardiometabolic health among children and adolescents, even in the absence of weight loss.

Normalized strength capacity is associated with lower cardiometabolic risk clustering in boys and girls, even after adjustment for cardiorespiratory fitness, level of physical activity, and BMI. (Read the full article)

Among US youth 6 to 15 years of age there are differences in strength by gender and age. Little is known about differences in strength by weight status in the US pediatric population.

This study provides current US nationally representative reference values for 4 measures of strength in youth 6 to 15 years old. Body weight was associated with strength, but the association varied depending upon the measure. (Read the full article)

Direct antiglobulin titer (DAT) positive, blood group A or B newborns born to group O mothers have a high incidence of hyperbilirubinemia, attributable to increased hemolysis.

DAT ++ readings were associated with a higher incidence of hyperbilirubinemia and a greater degree of hemolysis than DAT ± or DAT + counterparts. DAT strength should be taken into consideration when planning treatment strategies or follow-up of ABO-heterospecific newborns. (Read the full article)

Although the psychometric properties of the school-age Strengths and Difficulties Questionnaire (SDQ) have been extensively examined by using longitudinal data, the preschool version of the SDQ has only been explored in a limited number of cross-sectional studies.

This is the first psychometric study of the preschool SDQ using longitudinal data. We report measurement invariance over time, satisfactory reliability, construct and criterion validity, and predictive utility for subsequent behavioral problems (4 years) and clinical disorders (2 years). (Read the full article)

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

Winners to qualify automatically for UEFA Champions League while commercial rights are fully centralised from group stage

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

Needing God’s love and job skills, one young woman discovers a new future at OM Bangladesh’s residential discipleship programme.

During special Easter outreaches to women in red light areas, outreach workers go in the knowledge that Jesus is with them and His resurrection power gives hope, strength and life.

A community-based organization's partnership with researchers creates a 'knowledge neighborhood' supporting after-school programs.

In an effort to strengthen relationships with local churches, OM Chile recently held a dinner for local pastors that featured international flavours and testimonies.

Delaware farmers, between 18 and 40 years old have the opportunity to apply for the Young Farmers Loan Program through November 30, 2017. The program provides long-term, no-interest loans to help eligible farmers purchase land, reducing the financial impact on farmers just starting out or looking to expand.

NEW CASTLE (July 24, 2018) – Following a 14-month review of Delaware’s opioid use disorder treatment system, a research team from the Johns Hopkins Bloomberg School of Public Health and the Bloomberg American Health Initiative today recommended four major strategies to achieve the state’s goal of a system of care that is accessible, evidence-based, individualized, […]

With the country remaining under a lockdown due to coronavirus, the supply chain of essential goods has been disrupted, but, the same has also presented the government with an opportunity to identify and plug those gaps.

There were times when AICTE was a bed of corruption, but from that perspective we are today clean and more transparent.

Edtech players can supplement brick-and-mortar companies, but it’s difficult to replace them as students from classes 8th to 12th are young enough to be self-motivated to study themselves.

Special grade steel plates have been procured from the Bhilai plant of the Steel Authority of India Limited (SAIL) to be used in the launch vehicle.

(LAWRENCE KS) As the sun set Saturday over Memorial Field, the Indians and Bacone College kicked off game four of Haskell Football's season. Athletes and fans were pulling for a win against our rival Warriors. The Indians came out hard and fought endlessly through the night, but in the end, it would be experience that would win the game.

This is the 21st installment of The Rationalist, my column for the Times of India.

When all political parties agree on something, you know you might have a problem. Giriraj Singh, a minister in Narendra Modi’s new cabinet, tweeted this week that our population control law should become a “movement.” This is something that would find bipartisan support – we are taught from school onwards that India’s population is a big problem, and we need to control it.

This is wrong. Contrary to popular belief, our population is not a problem. It is our greatest strength.

The notion that we should worry about a growing population is an intuitive one. The world has limited resources. People keep increasing. Something’s gotta give.

Robert Malthus made just this point in his 1798 book, An Essay on the Principle of Population. He was worried that our population would grow exponentially while resources would grow arithmetically. As more people entered the workforce, wages would fall and goods would become scarce. Calamity was inevitable.

Malthus’s rationale was so influential that this mode of thinking was soon called ‘Malthusian.’ (It is a pejorative today.) A 20th-century follower of his, Harrison Brown, came up with one of my favourite images on this subject, arguing that a growing population would lead to the earth being “covered completely and to a considerable depth with a writhing mass of human beings, much as a dead cow is covered with a pulsating mass of maggots.”

Another Malthusian, Paul Ehrlich, published a book called The Population Bomb in 1968, which began with the stirring lines, “The battle to feed all of humanity is over. In the 1970s hundreds of millions of people will starve to death in spite of any crash programs embarked upon now.” Ehrlich was, as you’d guess, a big supporter of India’s coercive family planning programs. ““I don’t see,” he wrote, “how India could possibly feed two hundred million more people by 1980.”

None of these fears have come true. A 2007 study by Nicholas Eberstadt called ‘Too Many People?’ found no correlation between population density and poverty. The greater the density of people, the more you’d expect them to fight for resources – and yet, Monaco, which has 40 times the population density of Bangladesh, is doing well for itself. So is Bahrain, which has three times the population density of India.

Not only does population not cause poverty, it makes us more prosperous. The economist Julian Simon pointed out in a 1981 book that through history, whenever there has been a spurt in population, it has coincided with a spurt in productivity. Such as, for example, between Malthus’s time and now. There were around a billion people on earth in 1798, and there are around 7.7 billion today. As you read these words, consider that you are better off than the richest person on the planet then.

Why is this? The answer lies in the title of Simon’s book: The Ultimate Resource. When we speak of resources, we forget that human beings are the finest resource of all. There is no limit to our ingenuity. And we interact with each other in positive-sum ways – every voluntary interactions leaves both people better off, and the amount of value in the world goes up. This is why we want to be part of economic networks that are as large, and as dense, as possible. This is why most people migrate to cities rather than away from them – and why cities are so much richer than towns or villages.

If Malthusians were right, essential commodities like wheat, maize and rice would become relatively scarcer over time, and thus more expensive – but they have actually become much cheaper in real terms. This is thanks to the productivity and creativity of humans, who, in Eberstadt’s words, are “in practice always renewable and in theory entirely inexhaustible.”

The error made by Malthus, Brown and Ehrlich is the same error that our politicians make today, and not just in the context of population: zero-sum thinking. If our population grows and resources stays the same, of course there will be scarcity. But this is never the case. All we need to do to learn this lesson is look at our cities!

This mistaken thinking has had savage humanitarian consequences in India. Think of the unborn millions over the decades because of our brutal family planning policies. How many Tendulkars, Rahmans and Satyajit Rays have we lost? Think of the immoral coercion still carried out on poor people across the country. And finally, think of the condescension of our politicians, asserting that people are India’s problem – but always other people, never themselves.

This arrogance is India’s greatest problem, not our people.

© 2007 IndiaUncut.com. All rights reserved.
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This is the 21st installment of The Rationalist, my column for the Times of India.

When all political parties agree on something, you know you might have a problem. Giriraj Singh, a minister in Narendra Modi’s new cabinet, tweeted this week that our population control law should become a “movement.” This is something that would find bipartisan support – we are taught from school onwards that India’s population is a big problem, and we need to control it.

This is wrong. Contrary to popular belief, our population is not a problem. It is our greatest strength.

The notion that we should worry about a growing population is an intuitive one. The world has limited resources. People keep increasing. Something’s gotta give.

Robert Malthus made just this point in his 1798 book, An Essay on the Principle of Population. He was worried that our population would grow exponentially while resources would grow arithmetically. As more people entered the workforce, wages would fall and goods would become scarce. Calamity was inevitable.

Malthus’s rationale was so influential that this mode of thinking was soon called ‘Malthusian.’ (It is a pejorative today.) A 20th-century follower of his, Harrison Brown, came up with one of my favourite images on this subject, arguing that a growing population would lead to the earth being “covered completely and to a considerable depth with a writhing mass of human beings, much as a dead cow is covered with a pulsating mass of maggots.”

Another Malthusian, Paul Ehrlich, published a book called The Population Bomb in 1968, which began with the stirring lines, “The battle to feed all of humanity is over. In the 1970s hundreds of millions of people will starve to death in spite of any crash programs embarked upon now.” Ehrlich was, as you’d guess, a big supporter of India’s coercive family planning programs. ““I don’t see,” he wrote, “how India could possibly feed two hundred million more people by 1980.”

None of these fears have come true. A 2007 study by Nicholas Eberstadt called ‘Too Many People?’ found no correlation between population density and poverty. The greater the density of people, the more you’d expect them to fight for resources – and yet, Monaco, which has 40 times the population density of Bangladesh, is doing well for itself. So is Bahrain, which has three times the population density of India.

Not only does population not cause poverty, it makes us more prosperous. The economist Julian Simon pointed out in a 1981 book that through history, whenever there has been a spurt in population, it has coincided with a spurt in productivity. Such as, for example, between Malthus’s time and now. There were around a billion people on earth in 1798, and there are around 7.7 billion today. As you read these words, consider that you are better off than the richest person on the planet then.

Why is this? The answer lies in the title of Simon’s book: The Ultimate Resource. When we speak of resources, we forget that human beings are the finest resource of all. There is no limit to our ingenuity. And we interact with each other in positive-sum ways – every voluntary interactions leaves both people better off, and the amount of value in the world goes up. This is why we want to be part of economic networks that are as large, and as dense, as possible. This is why most people migrate to cities rather than away from them – and why cities are so much richer than towns or villages.

If Malthusians were right, essential commodities like wheat, maize and rice would become relatively scarcer over time, and thus more expensive – but they have actually become much cheaper in real terms. This is thanks to the productivity and creativity of humans, who, in Eberstadt’s words, are “in practice always renewable and in theory entirely inexhaustible.”

The error made by Malthus, Brown and Ehrlich is the same error that our politicians make today, and not just in the context of population: zero-sum thinking. If our population grows and resources stays the same, of course there will be scarcity. But this is never the case. All we need to do to learn this lesson is look at our cities!

This mistaken thinking has had savage humanitarian consequences in India. Think of the unborn millions over the decades because of our brutal family planning policies. How many Tendulkars, Rahmans and Satyajit Rays have we lost? Think of the immoral coercion still carried out on poor people across the country. And finally, think of the condescension of our politicians, asserting that people are India’s problem – but always other people, never themselves.

This arrogance is India’s greatest problem, not our people.

The India Uncut Blog © 2010 Amit Varma. All rights reserved.
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London event hears how the UK export credit agency is increasing its focus on trade with African countries. Jason Mitchell reports.

The minister of foreign affairs for Belarus tells fDi why the country is keen to join the WTO and strengthen economic relations with the CIS.

Scotland-based power and environmental consultant Aquatera Ltd. Has entered into a partnership with the Nagasaki Marine Industry Cluster Promotion Association in an effort to help Japan bolster its marine energy sector through international collaboration.

By East-West Center HONOLULU (October 4, 2019)—President Donald Trump first laid out a vision for a “free and open Indo-Pacific” at the November 2017 Asia-Pacific Economic Cooperation (APEC) Summit in Vietnam. From the start, statements describing the emerging US Indo-Pacific strategy have recognized the central role of Southeast Asia. The US approach to the Indo-Pacific focuses on three vital areas: enhancing shared prosperity, championing good governance and civil society, and ensuring a peaceful and secure regional order. Two recent visitors to the East-West Center described the potential role of the 10-member Association of Southeast Asian Nations (ASEAN) in the US Indo-Pacific strategy and spelled out several steps that the United States needs to take to strengthen US-ASEAN...

This is a summary only. Click the title for the full article, or visit www.EastWestCenter.org/Research-Wire for more.

On 2 December 2019, the European Council agreed to update Regulation 1371/2007 (the “Regulation”) on rail passengers’ rights and obligations. The proposed amendments to the Regulation aim to strengthen the rights of passengers wher...

New regulations on foreign investment in France were published on January 1, 2020. These texts make numerous changes to the legal framework for investment control in France. Financial relations between France and foreign countries are, in principle,...

Diplomatic Affairs: Marking two years since the move of the embassy to Jerusalem, David Friedman talks about annexation, the peace process and rapprochement in the Gulf.

1

The global value chains that help drive Asia’s export-driven economic miracle have widespread development impacts. We need to understand them better to maximize the benefits.

Past financial crises have demonstrated how adequate financial safety net arrangements—globally, regionally, and nationally—are vital to safeguarding financial stability.

ADB needs to address issues causing weak sustainability of its projects to improve performance, says the 2020 Annual Evaluation Review (AER) conducted by ADB’s Independent Evaluation Department.

ADB President Masatsugu Asakawa and AFD Chief Executive Officer Rémy Rioux held discussions today on strengthening the partnership between ADB and AFD to respond to the novel coronavirus disease (COVID-19) pandemic.