1 Moldovan Leu = 6.7823 Nepalese Rupee

1 Colombian Peso = 0.031 Nepalese Rupee

1 Uruguayan Peso = 2.8034 Nepalese Rupee

1 Uzbekistan Som = 0.012 Nepalese Rupee

1 Russian Ruble = 1.6475 Nepalese Rupee

1 Iraqi Dinar = 0.1016 Nepalese Rupee

1 Cayman Islands Dollar = 145.0844 Nepalese Rupee

1 Swiss Franc = 124.5502 Nepalese Rupee

1 CFA Franc BCEAO = 0.1999 Nepalese Rupee

1 Vietnamese Dong = 0.0052 Nepalese Rupee

1 Macedonian Denar = 2.1282 Nepalese Rupee

1 Zambian Kwacha = 0.0233 Nepalese Rupee

1 South Korean Won = 0.0991 Nepalese Rupee

1 Jordanian Dinar = 170.4515 Nepalese Rupee

1 Lebanese Pound = 0.0799 Nepalese Rupee

1 Bahraini Dinar = 319.7851 Nepalese Rupee

1 Chilean Peso = 0.1464 Nepalese Rupee

1 Maldivian Rufiyaa = 7.8005 Nepalese Rupee

1 Malaysian Ringgit = 27.9038 Nepalese Rupee

1 Nicaraguan Cordoba Oro = 3.5152 Nepalese Rupee

1 Netherlands Antillean Guilder = 67.3663 Nepalese Rupee

1 Estonian Kroon = 8.4793 Nepalese Rupee

1 Danish Krone = 17.5756 Nepalese Rupee

1 Fiji Dollar = 53.6768 Nepalese Rupee

1 New Zealand Dollar = 74.2303 Nepalese Rupee

1 Croatian Kuna = 17.4295 Nepalese Rupee

1 Peruvian Nuevo Sol = 35.5795 Nepalese Rupee

1 Dominican Peso = 2.1972 Nepalese Rupee

1 Papua New Guinean Kina = 35.2544 Nepalese Rupee

1 Brunei Dollar = 85.5724 Nepalese Rupee

Hi,

I am trying to use "sed -e 's " from SKILL code to edit unix file "FileA", to replace 3 words in the 2nd line.

How to run below multiple commands using  ipcBeginProcess, Should I use ipcWait or ipcCloseProcess ?

Using && to combine , will that work as I have to work serially on each command. ?

With below code only the first command gets executed. Please advise.

FileA="/user/tmp/text1.txt"

sprintf(Command1 "sed -e '2s/%s/%s/g' %s > %s" comment1 get(form concat("dComment" RDWn))->value FileA FileA)
cid = ipcBeginProcess(Command1)


sprintf(Command2 "sed -e '2s/%s/%s/g' %s > %s"  Time getCurrentTime() FileA FileA)
cid1 = ipcBeginProcess(Command2)


sprintf(Command3 "sed -e '2s/%s/%s/g' %s > %s"  comment2 get(form concat("Duser" RDWn))->value FileA FileA)
cid2 = ipcBeginProcess(Command3)

Thanks,

Ajay

HP ThinPro versions 7.1, 7.0, 6.2.1, and 6.2 suffer from an application filter bypass vulnerability.

HP ThinPro versions 7.1, 7.0, 6.2.1, and 6.2 suffer from a local physical access information disclosure vulnerability.

SGI IRIX 6.5 /usr/sysadm/bin/runpriv local root exploit.

Here is the short answer to the question of how many Microsoft products you can request: You can get 50 of each kind of product in a two-year period — but there are some exceptions.

See Microsoft products

What do you mean by "each kind of product"?

The Microsoft Donation Program divides products into categories called title groups. See the current list of 37. A title group contains products that serve essentially the same purpose, like PowerPoint and PowerPoint for Mac.

You can get products from 10 title groups in your two-year cycle.

When does this two-year cycle start and end? Is it the calendar year?

No. Your nonprofit has its own two-year cycle. Your first cycle started the day you requested your first Microsoft product through TechSoup. You can see when your current cycle ends on your Microsoft Donation Center page.

Outlook and PowerPoint are both title groups. Does that mean we can get 50 of each product?

That's right. They can be all the Windows version, all the Mac version, or a mixture of the two. And you will be able to request products from eight more title groups.

What are the exceptions you mentioned?

They have to do with servers. Microsoft offers two licensing models for its server products.

• Core-based licensing. This licensing is based on the number of cores in the physical processors of your server machines. The product page on TechSoup will tell you whether the server uses this type of licensing. You can request up to 50 of these products from each title group, the same as desktop products. But you might have to request more than one product to fully license all the processors in your server.
• Non-core-based licensing. You can request a total of five server products that do not use core-based licensing. They can be from a single title group or from different title groups, but the total cannot be more than five.

A lot of the title groups are for CALs and MLs. What are the limits for these?

You can get 50 from each title group.

CALs, or client access licenses, give you access to a server from a device like your desktop computer.

MLs, or management licenses, let your device be managed by a management server.

Where can I find out more?

This article goes into a lot more detail and gives examples of how the various allotments work together.

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What does it take to make a city greener? In San Francisco, it took a small group of motivated people to come together to create a nonprofit. After the city cut funding for urban forestry 36 years ago, seven individuals decided to take matters into their own hands. They created a nonprofit, Friends of the Urban Forest (FUF).

Starting with a Small Budget, FUF Plants Nearly Half San Francisco's Street Trees

The organization started off with just a small budget from a leftover city grant. Then it used grassroots efforts to rally neighborhoods throughout the city around urban trees. By empowering and supporting communities and homeowners to plant and care for their own trees, FUF has successfully planted 60,000 of the 125,000 trees in San Francisco. The group eventually even worked with the city to create San Francisco's first ever Urban Forest Plan.

FUF Harnesses the Power of Many Volunteers to Plant and Advocate for Trees

FUF is a member of TechSoup, and TechSoup's staffers were very excited to reach out for an interview to hear more about the group's impact. My team joined FUF early on a Saturday morning for its volunteer tree planting event in the Portola neighborhood, a part of the city that is lacking street trees. It was cold even by San Francisco standards, but there was an impressive turnout of volunteers present and ready to plant.

The executive director of FUF, Dan Flanagan, joined us and told us about his work. "We get to get out in the city and make it greener. We advocate for trees; I always call ourselves the Lorax of San Francisco. We are the only organization in San Francisco that is speaking for the trees."

FUF Gets the Chance to Plant Even More Trees … in Neighborhoods That Really Need Them

Dan was excited about a recent accomplishment for the organization. San Francisco just passed Proposition E, which opens up major opportunities for the nonprofit. As he said, "It changes the responsibility from street trees and sidewalks away from the homeowners and to the city. As a result, homeowners are no longer responsible, and now we actually get a chance to make the city more green than ever before by planting more trees in neighborhoods that couldn't afford it before."

This policy makes the city responsible for maintenance, but it will still require FUF to continue its work of planting the trees. FUF hopes to plant 1,700 trees this year and ultimately hopes to plant 3,000 trees every year.

FUF Puts Technology from TechSoup to Work

I was curious to find out how FUF was using technology to further its mission. Jason Boyce, individual gifts manager, said: "Here at Friends of the Urban Forest, a lot of our field staff tend to be out in the field all day; technology really needs to be out of the way to allow us to plant. So, as a result, the relationships we build with our community tend to be stronger because we use technology to enable our work, but it doesn't get in the way of our work."

Jason explained, "We have been working with ArcMap for years, ... GIS software that TechSoup has provided for us. We use it to plant trees, to figure out where we are going to plant. When we do our plantings, we actually dole out the maps that our volunteers use to do the plantings, and all that comes through ArcMap. We use Adobe Acrobat to put together our tree manuals for our new tree owners and volunteer manuals. We use AutoCAD to put together the permit drawings for our sidewalk gardens. Technology plays a really important role in doing our plantings and making San Francisco more green."

FUF Partners with the City to Calculate the Environmental Benefits of Trees

Jason also recently worked with the city on the Urban Forest Map, which is an interactive online map that tracks every tree in San Francisco. The map helps calculate the environmental benefits the trees provide, including stormwater mitigation, air pollutants captured, and carbon dioxide removed from the atmosphere. This platform has increased the visibility of the city's urban forest.

As Jason said, "We are now at the forefront of cities worldwide that are building software to manage their urban forests. … [This] really gives a lot of benefit to the people living in San Francisco."

TechSoup is proud to support organizations like Friends of the Urban Forest by enabling them with the technology they need. That support gives them more time to focus on their impact, like planting trees, or to build the communities that help them thrive.

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In 2015, the state of Louisiana consumed more energy per capita than any other state, according to the U.S. Energy Information Administration. Although this may not come as a complete surprise — the state's warm, muggy climate makes air conditioning a must — it's clear that Louisiana's energy-use profile needs a drastic transformation.

The Energy Wise Alliance (EWA), a small nonprofit based in New Orleans, is determined to do just that. Along the way, the organization has gotten a boost from Microsoft's MileIQ app.

MileIQ is a mobile app from Microsoft that automatically tracks the miles you've traveled and records all of your tax-deductible and reimbursable mileage. It's kind of like using a Fitbit, except you're tracking your driving. You can report your business drives on demand and claim your reimbursements or maximize your tax deductions. The average MileIQ user is logging $6,900 per year.

Building a More Energy-Efficient Community

EWA works to make energy efficiency more accessible to everyone. The organization works primarily with low-income families, tenants, and others who would otherwise be left out of the green energy revolution. EWA accomplishes its goals through both workshops and equipment upgrades at homes and businesses.

Its Energy Smart for Kids program teaches students throughout the state how to lead a more energy-efficient lifestyle. These hourlong sessions cover the pitfalls of nonrenewable energy and detail more sustainable alternatives. At the end of each session, EWA volunteers hand out energy-efficiency starter kits so students can apply what they learned at home.

Much like the rest of EWA's programs, Energy Smart for Kids serves underserved and underprivileged communities. In fact, many of the schools that EWA serves are Title 1 schools — schools whose students generally come from lower-income households.

Aside from schools, EWA also helps nonprofits become more sustainable.

Making Nonprofits Greener and More Cost-Efficient

Nonprofits can benefit from EWA's work by way of simple but effective power-saving retrofits. EWA also provides volunteer labor and donates the materials for the retrofits, which means added cost savings. And as we all know, cost-saving programs are like gold dust for nonprofits.

For example, volunteers from EWA revitalized the Victorian-era headquarters of the Alliance Française, a nonprofit dedicated to preserving Francophone heritage in the New Orleans community, with sustainable retrofits. As part of these upgrades, EWA sealed cracks, gaps, and openings; installed additional insulation; and programmed new thermostats.

In addition, EWA gave the Alliance Française's volunteers a hands-on demonstration of behavioral changes so that they could bring this knowledge back home. EWA anticipated that the Alliance Française would save a total of $2,000 to $3,000 as a result of these green improvements.

EWA's staff members also actively save money and operate more efficiently through the use of the mile-tracking app MileIQ.

Saving Time and Money with MileIQ

This method, as you can imagine, was time-consuming, and it brought with it the risk of human error. Most people can't possibly remember every single trip they make with their car, after all.

"MileIQ is super accurate and takes the forgetting out of the equation," said Jamie Wine, executive director of EWA.

For Kevin Kellup, education coordinator at EWA, MileIQ has been a game-changer. Jamie explained, "Kevin drives like crazy from school to school," racking up miles on his personal car. Now, thanks to MileIQ, Kevin can get more fairly and accurately reimbursed for his constant traveling.

The most important benefit of Microsoft's MileIQ for Jamie is that his staff can be correctly reimbursed for mileage. He wants to show staff members that he values their time and effort spent traveling, which MileIQ really helps him achieve.

For nonprofits, particularly small ones like EWA, it's always great when the team can receive fair compensation for its hard work. "The staff doesn't get paid much," Jamie said. And considering how important staff members' work is to the community, every penny matters. That's also where TechSoup comes in.

TechSoup's Role: "Essential"

Through TechSoup, eligible nonprofits can get MileIQ at 80 percent off the subscription rate. "Without TechSoup," Jamie noted, "this huge step up in technology" would not have been possible. The MileIQ discount program from Microsoft has made acquiring MileIQ way easier on the nonprofit's pocket.

Having also previously obtained Microsoft Office 365 and QuickBooks Online through TechSoup, Jamie said, "TechSoup is a great equalizer." He mentioned that TechSoup helps a small nonprofit to grow into a technologically advanced organization. He added, "The super discounted products from TechSoup are like the pot of gold at the end of the rainbow."

Getting MileIQ Premium

Eligible nonprofits can get MileIQ at 80 percent off the individual subscription rate through TechSoup and can request an unlimited number of individual subscriptions. In addition to individual subscriptions, MileIQ is now included with an Office 365 Business Premium license. Nonprofits who currently do not have an Office 365 license can visit Microsoft's Office 365 for nonprofits page to register.

This blog post was written by Nicholas Fuchs.

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Many nonprofits handle sensitive personal information belonging to community members — whether it's names or email addresses or payment information. But are you handling this data properly to prevent a data breach?

This post is by no means exhaustive — after all, every nonprofit handles different sorts of data, and each organization has different security needs. That said, these are some practical things to think about when you review your handling of sensitive personal information.

#1 Risk: Malware and Software Vulnerabilities

The Problem

This one may seem obvious, but with so many other security risks out there, it's easy to forget that malware still poses a major threat to your organization's data.

How You Can Mitigate It

To start, make sure you have antivirus software installed, and that it's up to date. In addition, you'll want to make sure your operating system and any software installed are also up to date, with all security patches installed.

Beyond that, be careful what you click on. Don't download and install software from sites you don't trust. Be careful of the email attachments and links you click on — even from people you know. If you aren't expecting a file or link, click with caution.

#2 Risk: Ransomware

The Problem

Ransomware is an especially insidious form of malware that holds your computer or data hostage unless you pay a sum of money to a criminal actor. Oftentimes, ransomware will encrypt your data, preventing you from accessing it. And according to Symantec's Director of Security Response Kevin Haley, some forms of ransomware will threaten to publicly release your data.

How You Can Mitigate It

Aside from up-to-date antivirus software and taking steps to avoid infection in the first place, there isn't a ton you can do to deal with a ransomware attack once your data's been encrypted.

In that case, according to Haley, keeping up-to-date backups of your data is your best bet. That way, you'll be able to get back up and running quickly with minimal data loss. (TechSoup offers backup and recovery solutions from Veritas.)

#3 Risk: Public Wi-Fi

The Problem

Public Wi-Fi is generally fine for some things, such as browsing cat videos on YouTube, or catching up on the headlines. However, for anything involving sensitive personal information, it's a security disaster waiting to happen. Bad actors could potentially eavesdrop on what you're doing while using public Wi-Fi, leaving your data and work open to prying eyes.

How You Can Mitigate It

First off, avoid using public, unsecured Wi-Fi when handling sensitive information — whether it's internal organizational data or your own personal banking information. Using a wireless hotspot, like those from Mobile Beacon (offered through TechSoup), instead of public Wi-Fi is an easy way to keep your data more secure.

If you can't avoid public Wi-Fi, a virtual private network (VPN) is a good option — VPNs secure data between your computer and the website you're visiting. Not all VPNs provide the same level of security, though, and you'll need to make sure your VPN of choice conforms to any data security regulations that your organization may be subject to. See our previous overview of VPNs for more.

#4 Risk: Inappropriate Sharing of Sensitive Information

The Problem

Sharing sensitive information via email, messaging apps, or similar means is a risky proposition.

Email is a notoriously insecure method of communication. Email accounts are often the target of data breaches and phishing attacks. (A phishing attack is where an attacker tries to steal your account information by tricking you to enter your account information on a phony login page.)

And whether it's through email or messaging app, it's all too easy to accidentally leak data by sharing it with the wrong person.

How You Can Mitigate It

Avoid sending sensitive information to colleagues via email. It's easier said than done, we know. Maybe you need to share a list of donor contact information with your marketing department, for example. Consider uploading it to a secure file server on your network that can only be accessed by others in the office.

If your organization uses a cloud storage service like Box, consider using that instead — so long as it meets your organization's security needs. These cloud storage services usually encrypt data you upload to prevent it from getting stolen. You may also want to consider using constituent relationship management (CRM) software, a tool designed specifically to store and manage your organization's contacts.

In addition, pay attention to access permissions. If you can, restrict access to sensitive information to only those who need it. Revisit your permissions settings regularly and update them as needed.

To prevent your user accounts from being compromised in the first place, practice good account security hygiene. Use strong passwords and require your staff to use two-factor authentication.

#5 Risk: Handling Credit Card Data

The Problem

A breach involving credit card data can be embarrassing for your organization, but it could wreak financial havoc on your members and supporters. All it takes is for hackers to grab a few pieces of information to rack up credit card debt in your supporters' names.

How You Can Mitigate It

Securing credit card information is important, but you don't have to make it up as you go. Make sure your organization conforms to payment card security standards. The Payment Card Industry Security Standards Council, as well as banks and credit card issuers, provide guidelines on how to best handle credit card information to prevent breaches.

Has your nonprofit recently encountered any other notable risks? Tell us about it in the comments!

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Exxon Mobil Corp. will use renewable energy to produce oil in West Texas.

The first coronavirus infection in the United States was confirmed in Seattle 100 days ago. A team of DER SPIEGEL reporters has documented what has happened since, following a dozen people as they struggle to come to terms with the health catastrophe.

Title: Interest in Unproven COVID Drugs Soared After Trump Gave Thumbs Up
Category: Health News
Created: 4/29/2020 12:00:00 AM
Last Editorial Review: 4/30/2020 12:00:00 AM

Title: Intense Exercise Can Trigger Heart Trouble in the Unprepared
Category: Health News
Created: 3/2/2020 12:00:00 AM
Last Editorial Review: 3/3/2020 12:00:00 AM

Title: U.S. Primary Care Docs Unprepared for Surge in Alzheimer's Cases
Category: Health News
Created: 3/11/2020 12:00:00 AM
Last Editorial Review: 3/11/2020 12:00:00 AM

ABSTRACT

The multifunctional nature of viral proteins is essentially driven by posttranslational modifications (PTMs) and is key for the successful outcome of infection. For influenza A viruses (IAVs), a composite pattern of PTMs regulates the activity of viral proteins. However, almost none are known that target the PB2 replication protein, except for inducing its degradation. We show here that PB2 undergoes a nonproteolytic ubiquitination during infection. We identified E3 ubiquitin ligases catalyzing this ubiquitination as two multicomponent RING-E3 ligases based on cullin 4 (CRL4s), which are both contributing to the levels of ubiquitinated forms of PB2 in infected cells. The CRL4 E3 ligase activity is required for the normal progression of the viral cycle and for maximal virion production, indicating that the CRL4s mediate a ubiquitin signaling that promotes infection. The CRL4s are recruiting PB2 through an unconventional bimodal interaction with both the DDB1 adaptor and DCAF substrate receptors. While able to bind to PB2 when engaged in the viral polymerase complex, the CRL4 factors do not alter transcription and replication of the viral segments during infection. CRL4 ligases catalyze different patterns of lysine ubiquitination on PB2. Recombinant viruses mutated in the targeted lysines showed attenuated viral production, suggesting that CRL4-mediated ubiquitination of PB2 contributes to IAV infection. We identified K29-linked ubiquitin chains as main components of the nonproteolytic PB2 ubiquitination mediated by the CRL4s, providing the first example of the role of this atypical ubiquitin linkage in the regulation of a viral infection.

IMPORTANCE Successful infection by influenza A virus, a pathogen of major public health importance, involves fine regulation of the multiple functions of the viral proteins, which often relies on post-translational modifications (PTMs). The PB2 protein of influenza A viruses is essential for viral replication and a key determinant of host range. While PTMs of PB2 inducing its degradation have been identified, here we show that PB2 undergoes a regulating PTM signaling detected during infection, based on an atypical K29-linked ubiquitination and mediated by two multicomponent E3 ubiquitin ligases. Recombinant viruses impaired for CRL4-mediated ubiquitination are attenuated, indicating that ubiquitination of PB2 is necessary for an optimal influenza A virus infection. The CRL4 E3 ligases are required for normal viral cycle progression and for maximal virion production. Consequently, they represent potential candidate host factors for antiviral targets.

The intracellular lifestyle of bacteria is widely acknowledged to be an important mechanism in chronic and recurring infection. Among the Staphylococcus genus, only Staphylococcus aureus and Staphylococcus pseudintermedius have been clearly identified as intracellular in nonprofessional phagocytic cells (NPPCs), for which the mechanism is mainly fibronectin-binding dependent. Here, we used bioinformatics tools to search for possible new fibronectin-binding proteins (FnBP-like) in other Staphylococcus species. We found a protein in Staphylococcus delphini called Staphylococcus delphini surface protein Y (SdsY). This protein shares 68% identity with the Staphylococcus pseudintermedius surface protein D (SpsD), 36% identity with S. aureus FnBPA, and 39% identity with S. aureus FnBPB. The SdsY protein possesses the typical structure of FnBP-like proteins, including an N-terminal signal sequence, an A domain, a characteristic repeated pattern, and an LPXTG cell wall anchor motif. The level of adhesion to immobilized fibronectin was significantly higher in all S. delphini strains tested than in the fibronectin-binding-deficient S. aureus DU5883 strain. By using a model of human osteoblast infection, the level of internalization of all strains tested was significantly higher than with the invasive-incompetent S. aureus DU5883. These findings were confirmed by phenotype restoration after transformation of DU5883 by a plasmid expression vector encoding the SdsY repeats. Additionally, using fibronectin-depleted serum and murine osteoblast cell lines deficient for the β₁ integrin, the involvement of fibronectin and β₁ integrin was demonstrated in S. delphini internalization. The present study demonstrates that additional staphylococcal species are able to invade NPPCs and proposes a method to identify FnBP-like proteins.

Anxiety levels soared to unprecedented heights around the time lockdown was announced in late March, according to the Government's official "happiness index".

The Trump administration failed to prepare for the onslaught of coronavirus, then sought a quick fix by trying to rush an unproven drug to patients, a senior government scientist has alleged in a whistleblower complaint.

Imaging specialist produces clearest pictures yet from dramatic Nasa mission