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Serotonin (5-HT) Shapes the Macrophage Gene Profile through the 5-HT2B-Dependent Activation of the Aryl Hydrocarbon Receptor [INNATE IMMUNITY AND INFLAMMATION]

By www.jimmunol.org
Published On :: 2020-05-04T13:00:28-07:00

Key Points

  • 5-HT2B agonists stimulate AhR transcriptional activation in human macrophages.

  • Serotonin-induced expression of AhR target genes is 5-HT2B dependent in macrophages.


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    Correction to "Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells" [Errata]

    By dmd.aspetjournals.org
    Published On :: 2020-04-09T08:02:00-07:00


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