Land O'Lakes ingredients puts signature touch on new "sea-salted caramel" dairy seasoning for snack, sauce and dip applications.

Zapp Brannigan wears quite the short miniskirt throughout Futurama, but the original design actually didn't intend to have him showing so much leg.

Lawley, C J M; Pearson, D G; Waterton, P; Zagorevski, A; Bédard, J H; Jackson, S E; Petts, D C; Kjarsgaard, B A; Zhang, S; Wright, D. Chemical Geology vol. 536, 119464, 2020 p. 1-17, https://doi.org/10.1016/j.chemgeo.2020.119464
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20190600.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20190600.jpg" title="Chemical Geology vol. 536, 119464, 2020 p. 1-17, https://doi.org/10.1016/j.chemgeo.2020.119464" height="150" border="1" /></a>

de Bronac de Vazelhes, V; McMartin, I; Côté-Mantha, O; Boulianne-Verschelden, N. Journal of Geochemical Exploration vol. 228, 106800, 2021 p. 1-17, https://doi.org/10.1016/j.gexplo.2021.106800
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20200684.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20200684.jpg" title="Journal of Geochemical Exploration vol. 228, 106800, 2021 p. 1-17, https://doi.org/10.1016/j.gexplo.2021.106800" height="150" border="1" /></a>

Swiss identity verification provider PXL Vision AG is responding to the growing demands on businesses. With the market launch of the software-as-a-service solution PXL Ident in April this year, the provider is expanding its AI-supported biometric identification process, which offers companies a secure way of verifying identity in online interactions.

Svartzonker is niet enkel een beroemde kunstaasbouwer, hij is ook een uitstekend hengelbouwer. We voelen ons vereerd om u een speciale roofvis serie aan te bieden waarvoor enkel uiterst lichte componenten gebruikt werden.

Signature Autohaus, a leader in automotive restyling, is excited to announce its expansion and relocation to a new, larger facility in Coral Springs, FL. This move marks a significant milestone in the company’s growth. It reflects its commitment to meeting the increasing demand for quality exotic and luxury auto restyling and performance within the community. The new location, situated at 3650 Coral Ridge Drive, [PR.com]

The heavily updated Hyundai Alcazar is a heady combination of space, luxury and practicality

RL Cafe is run by Bindhu KV and her husband, Balachandran T, in Thiruvananthapuram

A video on ‘Halwa Veedu’, where a family has been crafting broken-wheat halwa for decades

One important subject associated with personal authentication capabilities is the analysis of handwritten signatures. Among the many known techniques, algorithms based on linguistic formalisms are also possible. However, such techniques require a number of algorithms for intelligent image analysis to be applied, allowing the development of new solutions in the field of personal authentication and building modern security systems based on the advanced recognition of such patterns. The article presents the approach based on the usage of syntactic methods for the static analysis of handwritten signatures. The graph linguistic formalisms applied, such as the IE graph and ETPL(k) grammar, are characterised by considerable descriptive strength and a polynomial membership problem of the syntactic analysis. For the purposes of representing the analysed handwritten signatures, new hierarchical (two-layer) HIE graph structures based on IE graphs have been defined. The two-layer graph description makes it possible to take into consideration both local and global features of the signature. The usage of attributed graphs enables the storage of additional semantic information describing the properties of individual signature strokes. The verification and recognition of a signature consists in analysing the affiliation of its graph description to the language describing the specimen database. Initial assessments display a precision of the method at a average level of under 75%.

Felix Prangenberg got his first signature prototype from Wethepeople which has some unrivaled highlights to offer like the extruded chainstays and offset thickness bottom bracket shell. We will get the "Pathfinder" frame early in september and you can read some words of Felix and more details at the bike check of wethepeople (goto pathfinder bikecheck)! Best regards, Your kunstform BMX Shop

Kraft Signature Shreds are available in three debut offerings for the ultimate recipe versatility: Cheddar Blend, Mozzarella Blend, and Mexican Blend, all conveniently packaged in 8oz resealable bags. 

In addition to an already robust portfolio of cuts and flavors, including the recently added Nashville Hot pork loin filet, the new Hatch Chile tenderloin underscores Prairie Fresh’s commitment to quality, innovation and providing consumers with the best taste and flavor profiles possible.  

Made with Bob’s Red Mill’s signature blends of premium flours and quality pantry staples, each mix delivers light and fluffy pancakes in minutes. And, with home cooks preferring recipes with a short list of ingredients, they’ll become an essential shortcut for easy, convenient breakfasts with scratch-quality homemade taste. 

The company is debuting three just-add-water variations for homemade pancakes and waffles.

Schwan’s Consumer Brands, Inc.—a subsidiary of Schwan’s Company that offers trusted retail brands throughout the frozen-food category—has pushed forward in its innovation efforts and will launch new products under the Edwards brand.

Consumers can add eggs, butter or oil, and water for homemade baked goods with the new mixes.

Leading Commercial Glass Company in Salinas Now Offers Residential Solutions Across California's Central Coast

Signature Image Global School, the online academic institution affiliated with and stemming from Signature Image Academy International in Asia Singapore, announces the launch of its cutting-edge Advanced Diploma online learning programmes.

This integration centers on the strategic marketing opportunities associated with email signatures, enabling marketers to deliver personalized, data-driven communication that improves contact relationships and engagement

Electronic signatures would be allowed for all California workers’ compensation documents, under a recently amended bill. Assemblymember Diane Dixon, R-Newport Beach, last week amended AB 2337 to strike a provision that…

California lawmakers closed out the 2024 legislative session by passing a bill that would allow electronic signatures on all work comp documents, and a bill requiring that doctors who do utilization review on claims…

California Gov. Gavin Newsom signed a bill allowing electronic signatures in the state’s workers’ compensation system. Newsom on Sunday signed AB 2337, by Assemblymember Diane Dixon, R-Newport Beach. As introduced, the…

When exploring the arsenal of digital marketing tools, the concepts of email signature banner prominently feature as pivotal elements for interaction and outreach within the expansive domain of email marketing. While at a glance they may appear similar, email signatures [...]

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The post Harnessing the Power of Email Signatures and Banners in Digital Marketing first appeared on CSS Reset.

ETSI releases three specifications for cloud-based digital signatures

Sophia Antipolis, 2 April 2019

The ETSI technical committee on Electronic Signature Infrastructure (TC ESI) has just released a set of three Technical Specifications for cloud-based digital signatures supporting mobile devices: ETSI TS 119 431-1, ETSI TS 119 431-2 and ETSI TS 119 432. This new set of standards supports the creation of digital signatures in the cloud, facilitating digital signature deployment by avoiding the need for specialized user software and secure devices.

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ETSI standard to secure digital signatures solves issue for 4,000 banks

Sophia Antipolis, 17 March 2021

ETSI is pleased to unveil ETSI TS 119 182-1, a specification for digital signatures supported by PKI and public key certificates which authenticates the origin of transactions ensuring that the originator can be held accountable and access to sensitive resources can be controlled.

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ETSI virtual training on electronic signatures and trust services: register now!

Sophia Antipolis, 26 May 2021

The ETSI Technical Committee Electronic Signatures and Infrastructures (TC ESI) is organising a training on its standards on trust services and their use. This virtual event will take place on 1 June from 11:00 CEST to 15:00 CEST.

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ETSI eSignature testing event helps industry to comply with EU regulation

Sophia Antipolis, 22 July 2022

With the eIDAS Regulation, European Union Member States have put in place the necessary technical means to process electronically signed documents that are required when using an online service offered by, or on behalf of, a public sector body. In order to ensure that the cross-border dimension works in practice, testing needs to be done to mutually check Member States’ signatures against their existing digital signature validation applications.

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Sophia Antipolis, 20 September 2023

ETSI has published a new standard on “Requirements for trust service providers issuing publicly trusted S/MIME certificates” (ETSI TS 119 411-6 ) helping Trust Service Providers comply with new standards for S/MIME certificates that are enforced since 1 September 2023. Secure MIME (S/MIME) certificates are used to sign, verify, encrypt, and decrypt email messages. 

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Sophia Antipolis, 21 February 2024

ETSI’s first LTA Signature Augmentation and Validation Plugtests™ has seen international participants exchange over 35 000 digital signature validation reports.

Held from 23 October - 22 December 2023, the remote interoperability event was organized by the ETSI Centre for Testing and Interoperability (CTI), on behalf of ETSI’s Technical Committee for Electronic Signatures and Trust Infrastructures (TC ESI). This Plugtests™ event was facilitated with the support and co-funding of the European Commission (EC) and the European Free Trade Association (EFTA).

Conducted using a dedicated web portal, sessions over the month-long Plugtests™ attracted the involvement of 190 participants from 121 organizations across 38 countries.

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Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children | Communications Biology  Nature.com

Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures  Nature.com

Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer’s pathology  Nature.com

Serum proteomics reveal APOE-ε4 -dependent and APOE-ε4 -independent protein signatures in Alzheimer’s disease  Nature.com

Proteomic signatures improve risk prediction for common and rare diseases  Nature.com

Posted by Gordon Fyodor Lyon on May 05

Multipurpose Smart ID Card with PKI (Bio Digital Signature with Smart Card + e-ID + Credit Card)
Source: SG 17 Chairman
Study Questions: Q9/17

UPU-ITU mini workshop: Multipurpose Smart ID Card with PKI (Bio Digital Signature with Smart Card + e-ID + Credit Card)"
Source: TSB
Study Questions: Q9/17

PABCO Roofing’s entire Signature Cut line, including Paramount, Cascade, and Paramount Advantage, has earned UL 2218 Class 4 impact resistance, offering enhanced durability and aesthetic appeal.

Location: Electronic Resource- 

When Tina Berkett moved from New York City to Los Angeles in 2007, she immediately noticed the West Coast's creative spirit…

Maybe you shouldn't be surprised that Spokane's most notable distillery has an origin not unlike its host city…

By David Blackmon In the wake of the election of President Donald Trump to serve a second term in office, along with presumptive Republican majorities in both houses of Congress, many are now asking about what the future will hold for the oddly named Inflation Reduction Act. Trump made it repeatedly clear on the campaign […]

The post Biden’s Signature Climate ‘Boondoggle’ Might Be On Chopping Block After Trump Win appeared first on Liberty Unyielding.

Sean A Burnap
Dec 7, 2020; 0:RA120.002305v1-mcp.RA120.002305
Research

Tirsa L. E. van Westering
Dec 1, 2020; 19:2047-2067
Research

AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism that phosphorylates a wide range of proteins to maintain cellular homeostasis. AMPK consists of three subunits: α, β, and γ. AMPKα and β are encoded by two genes, the γ subunit by three genes, all of which are expressed in a tissue-specific manner. It is not fully understood, whether individual isoforms have different functions. Using RNA-Seq technology, we provide evidence that the loss of AMPKβ1 and AMPKβ2 lead to different gene expression profiles in human induced pluripotent stem cells (hiPSCs), indicating isoform-specific function. The knockout of AMPKβ2 was associated with a higher number of differentially regulated genes than the deletion of AMPKβ1, suggesting that AMPKβ2 has a more comprehensive impact on the transcriptome. Bioinformatics analysis identified cell differentiation as one biological function being specifically associated with AMPKβ2. Correspondingly, the two isoforms differentially affected lineage decision toward a cardiac cell fate. Although the lack of PRKAB1 impacted differentiation into cardiomyocytes only at late stages of cardiac maturation, the availability of PRKAB2 was indispensable for mesoderm specification as shown by gene expression analysis and histochemical staining for cardiac lineage markers such as cTnT, GATA4, and NKX2.5. Ultimately, the lack of AMPKβ1 impairs, whereas deficiency of AMPKβ2 abrogates differentiation into cardiomyocytes. Finally, we demonstrate that AMPK affects cellular physiology by engaging in the regulation of hiPSC transcription in an isoform-specific manner, providing the basis for further investigations elucidating the role of dedicated AMPK subunits in the modulation of gene expression.

Astrid M. Moerman
Dec 23, 2020; 0:jlr.RA120000974v1-jlr.RA120000974
Research Articles

Carotid atherosclerosis is a risk factor for ischemic stroke, one of the main causes of mortality and disability worldwide. The disease is characterized by plaques, heterogeneous deposits of lipids and necrotic debris in the vascular wall, which grow gradually and may remain asymptomatic for decades. However, at some point a plaque can evolve to a high-risk plaque phenotype, which may trigger a cerebrovascular event. Lipids play a key role in the development and progression of atherosclerosis, but the nature of their involvement is not fully understood. Using matrix-assisted laser desorption/ionization mass spectrometry imaging, we visualized the distribution of approximately 200 different lipid signals, originating of > 90 uniquely assigned species, in 106 tissue sections of 12 human carotid atherosclerotic plaques. We performed unsupervised classification of the mass spectrometry dataset, as well as a histology-directed multivariate analysis. These data allowed us to extract the spatial lipid patterns associated with morphological plaque features in advanced plaques from a symptomatic population, revealing spatial lipid patterns in atherosclerosis and their relation to histological tissue type. The abundances of sphingomyelin and oxidized cholesteryl ester species were elevated specifically in necrotic intima areas, while diacylglycerols and triacylglycerols were spatially correlated to areas containing the coagulation protein fibrin. These results demonstrate a clear co-localization between plaque features and specific lipid classes, as well as individual lipid species in high-risk atherosclerotic plaques.