Project monitoring plays a crucial role in project management, which is a part of every stage of a project's life-cycle. Nevertheless, along with the increasing ratio of outsourcing in many companies' strategic plans, project monitoring has been challenged by geographically dispersed project teams and culturally diverse team members. Furthermore, because of the lack of a uniform standard, data exchange between various project monitoring software becomes an impossible mission. These factors together lead to the issue of ambiguity in project monitoring processes. Ontology is a form of knowledge representation with the purpose of disambiguation. Consequently, in this paper, we propose the framework of an ontology-based real-time project monitoring system (ORPSM), in order to, by means of ontologies, solve the ambiguity issue in project monitoring processes caused by multiple factors. The framework incorporates a series of ontologies for knowledge capture, storage, sharing and term disambiguation in project monitoring processes, and a series of metrics for assisting management of project organizations to better monitor projects. We propose to configure the ORPMS framework in a cloud environment, aiming at providing the project monitoring service to geographically distributed and dynamic project members with great flexibility, scalability and security. A case study is conducted on a prototype of the ORPMS in order to evaluate the framework.

We identified a de novo heterozygous transient receptor potential cation channel subfamily M (melastatin) member 3 (TRPM3) missense variant, p.(Asn1126Asp), in a patient with developmental delay and manifestations of cerebral palsy (CP) using phenotype-driven prioritization analysis of whole-genome sequencing data with Exomiser. The variant is localized in the functionally important ion transport domain of the TRPM3 protein and predicted to impact the protein structure. Our report adds TRPM3 to the list of Mendelian disease–associated genes that can be associated with CP and provides further evidence for the pathogenicity of the variant p.(Asn1126Asp).

The Bastille Hardening program locks down an operating system, configuring the system for increased security. It currently supports Red Hat, Fedora Core, Red Hat Enterprise, SuSE, SuSE Enterprise, Mandrake, Debian, and Gentoo, HP-UX, and Apple's Mac OS X. Screenshot available here..

The Bastille Hardening program locks down an operating system, configuring the system for increased security. It currently supports Red Hat, Fedora Core, Red Hat Enterprise, SuSE, SuSE Enterprise, Mandrake, Debian, and Gentoo, HP-UX, and Apple's Mac OS X. Screenshot available here..

The Bastille Hardening program locks down an operating system, configuring the system for increased security. It currently supports Red Hat, Fedora Core, Red Hat Enterprise, SuSE, SuSE Enterprise, Mandrake, Debian, and Gentoo, HP-UX, and Apple's Mac OS X. Screenshot available here..

The Bastille Hardening program locks down an operating system, configuring the system for increased security. It currently supports Red Hat, Fedora Core, Red Hat Enterprise, SuSE, SuSE Enterprise, Mandrake, Debian, and Gentoo, HP-UX, and Apple's Mac OS X. Screenshot available here..

With an action-packed Mobile World Congress behind us, HARMAN continued the momentum by revealing a range of breakthrough in-car audio and infotainment experiences at the Geneva International Motor Show 2019. At this event in Switzerland, HARMAN’s...

Ohio-based RPM International Inc. and its subsidiary, Tremco Inc., have paid $60.9 million to resolve allegations that Tremco filed false claims in connection with two multiple award schedule (MAS) contracts with the General Services Administration (GSA) for roofing supplies and services.