Spyrosoft today announced it has joined NVIDIA Inception, a program designed to nurture startups revolutionising industries with advancements in AI and data science.

Manufacturing

Candida albicans and Aspergillus fumigatus are dangerous fungal pathogens with high morbidity and mortality, particularly in immunocompromised patients. Innate immune-mediated programmed cell death (pyroptosis, apoptosis, necroptosis) is an integral part of host defense against pathogens. Inflammasomes, which are canonically formed upstream of pyroptosis, have been characterized as key mediators of fungal sensing and drivers of proinflammatory responses. However, the specific cell death pathways and key upstream sensors activated in the context of Candida and Aspergillus infections are unknown. Here, we report that C. albicans and A. fumigatus infection induced inflammatory programmed cell death in the form of pyroptosis, apoptosis, and necroptosis (PANoptosis). Further, we identified the innate immune sensor Z-DNA binding protein 1 (ZBP1) as the apical sensor of fungal infection responsible for activating the inflammasome/pyroptosis, apoptosis, and necroptosis. The Zα2 domain of ZBP1 was required to promote this inflammasome activation and PANoptosis. Overall, our results demonstrate that C. albicans and A. fumigatus induce PANoptosis and that ZBP1 plays a vital role in inflammasome activation and PANoptosis in response to fungal pathogens.

Following a tease, Microsoft and Activision Blizzard have announced Spyro Reignited Trilogy will release for Xbox Game Pass tomorrow, November 12.

VGChartz staff gave Spyro Reignited Trilogy an 8 out of 10 and stated, "it was wise to steer away from marketing the collection as a remaster because that label undercuts the developers’ level of dedication and investment in revitalizing these games."

Read details on the trilogy below:

Remade from the ground up, the Spyro Reignited Trilogy features all three of the original games that started it all – Spyro the Dragon, Spyro 2: Ripto’s Rage, and Spyro: Year of the Dragon, amazing for the original fans and new players alike.

Spyro the Dragon

Our new favorite little purple dragon starts on a quest to rescue his dragon friends who have been turned into crystal by the villain Gnasty Gnorc (what an unfortunate and yet apt name!). Spyro explores vibrant Dragon Realms, collects gems, and flambés his enemies, all while learning to how breathe fire and glide.

Spyro 2: Ripto’s Rage!

Spyro finds himself in the magical land of Avalar where he is trying to save the realm from the evil sorcerer Ripto and his minions. Along the way, he befriends new entirely new allies, overcomes challenges, complete tasks, and unlocks even more powers to take down Ripto and restore peace.

Spyro: Year of the Dragon

In Spyro: Year of the Dragon, Spyro finds out that the Dragon Eggs have been stolen by the devious Sorceress, sending him on a new mission to recover the eggs and save the dragon population. Our favorite purple dragon meets new friends, learns new abilities, all while exploring more vibrant realms with challenges (and treasures!).

Xbox players have been able to explore the Dragon Realms with Spyro since 2018 with the release of the Reignited Trilogy, and now we’re excited to invite our community to jump into these incredible adventures once again and relive the fun and nostalgia that only Spyro can bring.

Available on Game Pass Standard, Game Pass Ultimate, and PC Game Pass, for cloud, console and PC, it’s sure to ignite some serious fun. Let’s go save the Dragon Realms!

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463034/spyro-reignited-trilogy-headed-to-xbox-game-pass-tomorrow-november-12/

Pyrotechnician Patrick Cyrana joins WIRED to answer your burning questions about fireworks. How are fireworks designed? How do they get their color? What is the most dangerous firework statistically? Who invented fireworks? How do you become a professional pyrotechnician. Patrick answers all of these questions and more—it’s Fireworks Support. Director: Lisandro Perez-Rey Director of Photography: Constantine Economides Editor: Richard Trammell Expert: Patrick Cyrana Line Producer: Joseph Buscemi Associate Producer: Paul Gulyas; Brandon White Production Manager: Peter Brunette Casting Producer: Nicholas Sawyer Camera Operator: Mar Alfonso Sound Mixer: Rebecca ONeil Production Assistant: Ryan Coppola Post Production Supervisor: Christian Olguin Post Production Coordinator: Ian Bryant Supervising Editor: Doug Larsen Additional Editor: Jason Malizia; JC Scruggs Assistant Editor: Justin Symonds

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting

Dec 4-5, 2019 in Greenville, SC

Disclosed is a process for biomass conversion which includes co-processing the biomass with thermoplastic and non-thermoplastic polymer based materials in a catalytic pyrolysis reactor to convert such to liquid hydrocarbons; wherein hydrogen atoms originating with the polymer materials can remove oxygen from oxygenated hydrocarbons produced in the conversion of the biomass in the reactor.

This invention is provided for improvement of corrosion-resistant property of a crucible and for promotion of safety in a pyrochemical reprocessing method for the spent nuclear fuel. The spent nuclear fuel is dissolved in a molten salt placed in the crucible. In a pyrochemical reprocessing method, the nuclear fuel is deposited, and the crucible (2) is heated by induction heating. Cooling media (5, 6) are supplied to cool down, and a molten salt layer (7) is maintained by keeping balance between the heating and the cooling, and a solidified salt layer (8) is formed on inner wall surface of the crucible.

An apparatus for producing disilane through pyrolysis of monosilane, includes: a monosilane pyrolysis unit; a solid particle removal unit which removes solid particles generated in the pyrolysis unit; a condensing unit which liquefies and collects unreacted monosilane, and disilane and higher silanes with three (3) to seven (7) silicon atoms as pyrolysis products excluding hydrogen from a gas with the solid particles removed; a first separation unit which separates monosilane from a mixture of the liquefied unreacted monosilane, disilane and higher silanes; and a second separation unit which separates disilane and higher silanes from the mixture with the monosilane removed. In accordance with the present disclosure, disilane can be produced economically and efficiently with high purity through pyrolysis of monosilane.

A pyrolytic conversion assembly for processing biomass including: a rotary kiln including a tube for heating the biomass at pressure having a sealable inlet at a first, higher end for ingress of the biomass, and a sealable outlet at a lower end for egress of charcoal formed from the biomass; and heating elements disposed around the kiln to provide a localized source of heating at a predetermined distance from the sealable inlet for reflux condensation of gas from the biomass.

Mechanical visbreaking and pyrolysis between counter-rotating coaxial centrifugal impellers in a continuous radial counterflow process minimizes wastewater discharges. In one example, a cataclastic shear retort comminutes, shear thins, and shear heats an axial feed, such as tar sand, oil shale, coal tailings, distillation bottoms, or lignite. Pyrolyzing the feedstock in this shear retort yields a product stream of gases, naphthas, and oils which first mixes with the feedstock and then is axially extracted, while spent solids are simultaneously extruded from the periphery as coked devolatilized residue, such as char sand for upgrading soil to terra preta. Recirculation of shear-heated solids in long residence time within the shear retort brings heat from the spent solids at the periphery to the feedstock without an external heated sand loop. CO2 emissions from combustion to heat water for oil extraction are eliminated.

A process for the controlled gasification of a carbonaceous feedstock includes pyrolizing the feedstock by conveying the feedstock through a retort surrounded by a plurality of successive heating chambers each comprising an axially adjustable chamber separation wall and each operated at a predetermined temperature, wherein a predetermined dwell time of the feedstock in each of the plurality of successive heating chambers is controlled by a conveyance rate of the feedstock through the retort and a position of each of the axially adjustable chamber separation walls to produce a gas product and a solid product. The gas product includes methane and noxious chemicals and the solid product includes carbon, and the pyrolizing step is controlled using feedback related to constituents of the gas product.

The present invention provides a microwave assisted flash pyrolysis system to carry out microwave assisted flash pyrolysis in an industrial scale. The microwave assisted flash pyrolysis system comprises at least one microwave generator; a chamber comprises: at least one feedstock inlet, at least one baffle plate, a microwave-transparent rotating window, and at least one microwave inlet, at least one wet gas outlet, and at least one dry end product outlet. The present invention also provides a method using the same system to carry out microwave assisted flash pyrolysis.

Method for fast pyrolysis of lignocellulose including: mechanically comminuting the lignocellulose to lignocellulose particles; at least one of completely drying and preheating the lignocellulose particles; mixing the lignocellulose particles with heat transfer particles so as to provide a mixture; heating the heat transfer particles, prior to the mixing, to a temperature between 500° C. and 650° C.; and heating, in a pyrolysis reactor with oxygen excluded, the lignocellulose particles using the heat transfer particles so as to establish a temperature between 400° C. and 600° C. for 1 to 50 seconds and so as to react the lignocellulose particles so as to provide pyrolysis coke, pyrolysis condensate, and pyrolysis gas.

This invention relates to a process for thermochemically transforming biomass or other oxygenated feedstocks into high quality liquid hydrocarbon fuels. In particular, a catalytic hydropyrolysis reactor, containing a deep bed of fluidized catalyst particles is utilized to accept particles of biomass or other oxygenated feedstocks that are significantly smaller than the particles of catalyst in the fluidized bed. The reactor features an insert or other structure disposed within the reactor vessel that inhibits slugging of the bed and thereby minimizes attrition of the catalyst. Within the bed, the biomass feedstock is converted into a vapor-phase product, containing hydrocarbon molecules and other process vapors, and an entrained solid char product, which is separated from the vapor stream after the vapor stream has been exhausted from the top of the reactor. When the product vapor stream is cooled to ambient temperatures, a significant proportion of the hydrocarbons in the product vapor stream can be recovered as a liquid stream of hydrophobic hydrocarbons, with properties consistent with those of gasoline, kerosene, and diesel fuel. Separate streams of gasoline, kerosene, and diesel fuel may also be obtained, either via selective condensation of each type of fuel, or via later distillation of the combined hydrocarbon liquid.

A system and method for processing biomass into hydrocarbon fuels that includes processing a biomass in a hydropyrolysis reactor resulting in hydrocarbon fuels and a process vapor stream and cooling the process vapor stream to a condensation temperature resulting in an aqueous stream. The aqueous stream is sent to a catalytic reactor where it is oxidized to obtain a product stream containing ammonia and ammonium sulfate. A resulting cooled product vapor stream includes non-condensable process vapors comprising H2, CH4, CO, CO2, ammonia and hydrogen sulfide.

Pyrolysis fuels and methods for processing pyrolysis fuel are provided. In one embodiment, a method of processing pyrolysis fuel converts biomass to pyrolysis fuel including pyrolysis oil and char particles. Also, the method includes resizing a portion of the char particles so that substantially all resized char particles have a largest dimension no greater than about 5 microns.

A pyrolysis device and process to convert a carbonaceous feedstock to a carbon solid and pyrolysis gas, and processes for refining the resulting carbon solid and pyrolysis gases. The pyrolysis process may include introducing a carbonaceous feedstock into a pyrolysis processor having a vertical rotary tray processor, heating the feedstock to a temperature above about 790° F., removing a carbon material from a bottom of the pyrolysis processor, and removing a pyrolysis gas from a top of the pyrolysis processor.

The disclosure encompasses in-line reactive condensation processes via vapor phase esterification of bio-oil to decease reactive species concentration and water content in the oily phase of a two-phase oil, thereby increasing storage stability and heating value. Esterification of the bio-oil vapor occurs via the vapor phase contact and subsequent reaction of organic acids with ethanol during condensation results in the production of water and esters. The pyrolysis oil product can have an increased ester content and an increased stability when compared to a condensed pyrolysis oil product not treated with an atomized alcohol.

The device and method are provided to increase anhydrosugars yield during pyrolysis of biomass. This increase is achieved by injection of a liquid or gas into the vapor stream of any pyrolysis reactor prior to the reactor condensers. A second feature of our technology is the utilization of sonication, microwave excitation, or shear mixing of the biomass to increase the acid catalyst rate for demineralization or removal of hemicellulose prior to pyrolysis. The increased reactivity of these treatments reduces reaction time as well as the required amount of catalyst to less than half of that otherwise required. A fractional condensation system employed by our pyrolysis reactor is another feature of our technology. This system condenses bio-oil pyrolysis vapors to various desired fractions by differential temperature manipulation of individual condensers comprising a condenser chain.

A pyrolyzer apparatus (i.e. a “cracking pipe”) comprises a first screen, a second screen, and a catalyst material positioned between the first and second screens. The pyrolyzer is structured so that feedstock is pyrolyzed and pyrolyzer-generated gas is drawn through the first screen, through the catalyst material, and then through the second screen in series. The gas may then be directed to other processing equipment so that bio-oil is extracted from the gas.

A particulate form carbon pyrolyzate adsorbent, having the following characteristics: (a) CO2 capacity greater than 105 cc/gram at one bar pressure and temperature of 273° Kelvin; (b) CO2 Working Capacity greater than 7.0 weight percent; (c) CO2 heats of adsorption and desorption each of which is in a range of from 10 to 50 kJ/mole; and (d) a CO2/N2 Henry's Law Separation Factor greater than 5. The carbon pyrolyzate material can be formed from a polyvinylidene chloride-based polymer or copolymer, or other suitable resin material, to provide an adsorbent that is useful for carbon dioxide capture applications, e.g., in treatment of flue gases from coal-fired power generation plants.

A lead-free pyrotechnic and primary explosive compositions including metal iodates as an oxidizer in nanocomposite energetic compositions including metal powder fuel.

The invention is directed to a method for preparing a pyrotechnic composition, to the use of a water-soluble cellulose ether binder, to a pyrotechnic composition, to a method for preparing a pyrotechnic charge, and to a pyrotechnic charge. The method of the invention comprises mixing the fibrous nitrocellulose in wet form with the one or more water-soluble cellulose ether binders and optionally one or more solvents, wherein the amount of organic solvent in the mixture is 10 wt. % or less based on total weight of the mixture.

A powdery pyrotechnic mixture is proposed that comprises a binary or ternary inorganic oxidizing agent mixture composed of one or two metal oxides, a nitrate totaling 50.0% by weight to 85.0% by weight, an elementary inorganic fuel or a mixture of elementary inorganic fuels totaling 15.0% by weight to 40.0% by weight, a stabilized nitrocellulose or a nitrocellulose-based propellant powder from 0.0% by weight to 25.0% by weight, graphite from 0.0% by weight to 5.0% by weight as well as. Optionally. a further processing aid from 0.0% by weight to 5.0% by weight. The powdery pyrotechnic mixture excels in that it contains no chlorate-containing compound and/or perchlorate-containing compound as an oxidizing agent and no sulfur or a sulfur-containing compound as fuel. The proposed pyrotechnic mixture is used in pyrotechnic objects and ammunition for the production of a bang-effect and/or flash effect.

The pyrotechnic smoke kit for generating a smoke screen comprises a mixture of a light-metal powder as the metallic reduction agent; potassium nitrate and, optionally, potassium perchlorate as the main oxidation agent; at least one carbonate as an additional auxiliary oxidation agent; substances splitting off nitrogen as combustion moderators and at least one sublimable and/or evaporable non-toxic smoke-forming substance. A stabilizer from the group of aliphatic and/or aromatic dicarboxylic acids is added to the mixture of the smoke kit to stabilize the smoke kit. Due to this, the formation of gaseous ammonia in the smoke kit can be prevented.

Described herein are systems and methods for achieving fast pyrolysis of wood and other carbonaceous solids in rotary reactors. Novel heating, feeding and condensing methods result in high oil yields near those currently achieved with more complicated fast pyrolysis systems. High intensity burners are arranged and controlled to produce high heating rates and uniform temperature of the rotating cylindrical walls of the reactors. The feeding system delays the onset of pyrolysis until the solids fall onto the heated kiln walls. The pyrolysis gases and vapors are rapidly withdrawn and quenched with recycled liquids. The first condenser incorporates a clean out nozzle. Char products are readily separated and discharged into a heat exchanger where heat is recovered and used together with heat from reactor flue gas to dry the solids prior to being fed to the reactor.

A method and apparatus for upgrading coal and other carbonaceous fuels includes subjecting the carbonaceous fuel to a pyrolyzing process, thereby forming upgraded carbonaceous fuel and a flow of lean fuel gases. Auxiliary fuel is combusted in an auxiliary fuel combustor to produce auxiliary fuel combustion gases, and the lean fuel gases are heated with the auxiliary fuel combustion gases. The heated lean fuel gases are combusted in a lean fuel combustor, thereby producing a gas stream of products of combustion, and at least a portion of the gas stream of products of combustion are directed to the pyrolyzer.

The present disclosure provides robust, high-throughput, and clinically applicable methods for simultaneously separating and quantifying the biologically active forms of Vitamin B1 (TPP) and Vitamin B6 (PLP) from human whole blood.

Budapest : Franklin-Verein, 1895.

Inflammasomes assemble in the cytosol of myeloid and epithelial cells on sensing of cellular stress and pathogen-associated molecular patterns and serve as scaffolds for recruitment and activation of inflammatory caspases. Inflammasomes play beneficial roles in host and immune responses against diverse pathogens but may also promote inflammatory tissue damage if uncontrolled. Gasdermin D (GSDMD) is a recently identified substrate of murine caspase-1 and caspase-11, and human caspases-1, -4, and -5 that mediates a regulated lytic cell death mode termed pyroptosis. Recent studies have identified pyroptosis as a critical inflammasome effector mechanism that controls inflammasome-dependent cytokine secretion and contributes to antimicrobial defense and inflammasome-mediated autoinflammatory diseases. Here, we review recent developments on inflammasome-associated effector functions with an emphasis on the emerging roles of gasdermin pores and pyroptosis.

Sydney claims the largest and most technologically advanced annual fireworks display on the planet, attracting more than one million people to the harbour foreshore, more than turn out for the fireworks in New York,

Imports of Explosive & Pyrotechnic Products in Japan increased to 947.81 JPY Million in March from 751.85 JPY Million in February of 2020. Imports of Explosive & Pyrotechnic Products in Japan averaged 848.08 JPY Million from 1988 until 2020, reaching an all time high of 2092.69 JPY Million in February of 1996 and a record low of 140.06 JPY Million in March of 1988. This page includes a chart with historical data for Japan Imports of Explosive & Pyrotechnic Products.

The gorgeous Doberman Pyro has been by Kendall Jenner's side ever since May 2018, including during the recent coronavirus pandemic sweeping the world.

As an alternative to incineration that is known to produce toxic pollutants like dioxins, India is leaning towards pyrolysis for disposal of medical waste. Ratna Singh of New Delhi based Toxics Link on the implications.

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