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2<sup>nd</sup> meeting pro-iBiosphere

Pro-iBiosphere meeting 2 will be held from 11 to 14 February 2013 in Leiden. It will consist of three workshops on: e-platforms & e-tools for taxonomy Legacy literature – Semantic mark-up generation, data quality and user-participation infrastructure Prospective Literature – Toward Best Practices for data acquisition and curation using e-tools for taxonomy. More information can be found at: http://wiki.pro-ibiosphere.eu/wiki/Workshops_Leiden_February_2013





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3<sup>rd</sup> meeting pro-iBiosphere

Pro-iBiosphere meeting 3 will be held from 20 to 24 May 2013 in Berlin. It will consist of three workshops on: 1) Coordination and routes for cooperation across organizations, projects and e-infrastructures 2) Measuring and constraining the costs of delivering services 3) Stakeholder requirements Second Management committee meeting and Advisory Board meetings will be held from 23-24 of May 2013. More information can be found at: http://wiki.pro-ibiosphere.eu/wiki/Workshops_Berlin,_May_2013

 





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<b>More Love, Less Labor: AI Powers Productivity at Autodesk University</b><o:p></o:p>

The message from Autodesk and the many companies that presented and exhibited at Autodesk University (AU) last month in San Diego was clear: for the product design and manufacturing (D&M), architecture, engineering, construction and operations (AECO), and media and entertainment (M&E) industries, AI is a driving force behind productivity.

Autodesk University Mainstage

Data, data, data

AI-driven productivity is customized to the specific needs of each industry, with various generative and multimodal AI models providing solutions for tasks like workflow optimization, manufacturing quality assurance, regulatory compliance, and design visualization. However, the value of AI across these sectors—and beyond—is determined by the quantity and quality of data used.

Quantity matters because more data enables AI systems to learn and improve. Quality, however, is more complex. It requires obtaining relevant data, ensuring data accuracy, and verifying that data usage complies with ethical standards.

Dell demonstrated how their workstations can run generative AI 3D content with NVIDIA Edify trained on Shutterstock ethically sourced content.

Customers are key

The importance of AI and data was evident throughout AU, with presentations and product demonstrations highlighting customer-centric solutions. Hardware providers showcased high-performance workstations equipped with powerful processors, optimized to support AI workloads. Meanwhile, data and asset management providers emphasized AI’s capabilities in extracting valuable information, managing metadata, and monitoring workflows in real time.

Lenovo displayed next generation workstations designed with a customer-centric focus. Partnering with Intel®, NVIDIA and Aston Martin, they offer high-end graphics, memory and processing power.

Autodesk’s Design & Manufacturing team showcased how they are addressing their customers' needs by delivering AI-powered efficiencies through Fusion, a cloud-based, unified platform for design and manufacturing. They also introduced Project Bernini, a research initiative focused on a new approach to generative AI. Unlike many generative models that prioritize the appearance of 3D objects, Bernini emphasizes generating structural 3D data from the inside out, which aligns closely with real-world production needs.


Experimental research project Bernini model generates shape and texture separately and does not confuse or meld those variables.

AI provides a wide range of possibilities based on industry-specific needs. For entertainment and gaming, AI can generate lifelike product and character models, while in manufacturing and design, it lays the foundation for real-world production. With tools like Fusion and research projects like Bernini, Autodesk aims to empower creators and makers to leverage AI for both efficiency and innovation.

 




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India Nature Watch - <h1> <font color = blue> Blister Beetle <h1/p>

Thanks to Sivakumar ji for the ID

Hycleus zigzagus

Gear: Sony A7 III

Blister beetles are beetles of the family Meloidae, so called for their defensive secretion of a blistering agent,

cantharidin. About 7,500 species are known worldwide. Many are conspicuous and some are

aposematically colored, announcing their toxicity to would-be predators.




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India Nature Watch - <h1> <font color = blue> Hummingbird moth <h1/p>

The flowers of the snakeweed plant are popular with many butterflies, including the

South Asian crimson rose, Malabar banded swallowtail, grass yellow, and hummingbirds.

Smaller species of butterflies, like the Common Palmfly and the Bush Browns,

are often seen feeding on the flowers. Larger butterflies, like the Polyura and Lexias,

have not been seen feeding on the plant.




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India Nature Watch - <h1> <font color = blue> Blue mud dauber wasp <h1/p>

Thanks to Sivakumar ji for correcting the ID.

Family: Scoliidae




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Designing of improved drugs for COVID-19: Crystal structure of SARS-CoV-2 main protease M<sup>pro</sup>




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Precise test of quantum electrodynamics and determination of fundamental constants with HD<sup>+</sup> ions




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Antibody-free enzyme-assisted chemical approach for detection of <i>N</i><sup>6</sup>-methyladenosine




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A metabolic labeling method detects m<sup>6</sup>A transcriptome-wide at single base resolution




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Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




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Short-term NAD<sup>+</sup> supplementation prevents hearing loss in mouse models of Cockayne syndrome




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Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial




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Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca<sup>2+</sup> channel internalization in mesenchymal stem cells




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[ASAP] Lanthanide 5,7-Disulfonate-1,4-naphthalenedicarboxylate Frameworks Constructed from Trinuclear and Tetranuclear Lanthanide Carboxylate Clusters: Proton Conduction and Selective Fluorescent Sensing of Fe<sup>3+</sup>

Inorganic Chemistry
DOI: 10.1021/acs.inorgchem.0c00680




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[ASAP] An Inconspicuous Six-Coordinate Neutral Dy<sup>III</sup> Single-Ion Magnet with Remarkable Magnetic Anisotropy and Stability

Inorganic Chemistry
DOI: 10.1021/acs.inorgchem.0c00616




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[ASAP] Correlating Electronic Structure and Magnetic Anisotropy in Actinide Complexes [An(COT)<sub>2</sub>], An<sup>III/IV</sup> = U, Np, and Pu

Inorganic Chemistry
DOI: 10.1021/acs.inorgchem.0c00105




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[ASAP] Charge-Separation-Type Ionic Crystals with Mixed Au<sup>I</sup><sub>4</sub>Co<sup>III</sup><sub>2</sub> and Au<sup>I</sup><sub>4</sub>Ni<sup>II</sup>Co<sup>II

Inorganic Chemistry
DOI: 10.1021/acs.inorgchem.0c00872




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[ASAP] Construction of Ln<sup>3+</sup>-Substituted Arsenotungstates Modified by 2,5-Thiophenedicarboxylic Acid and Application in Selective Fluorescence Detection of Ba<sup>2+</sup> in Aqueous Solution

Inorganic Chemistry
DOI: 10.1021/acs.inorgchem.0c00223




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[ASAP] Macrocyclic Pyclen-Based Gd<sup>3+</sup> Complex with High Relaxivity and pH Response

Inorganic Chemistry
DOI: 10.1021/acs.inorgchem.0c00690




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[ASAP] Acylphloroglucinol Derivatives with a Tricyclo-[4.4.1.1<sup>1,4</sup>] Dodecane Skeleton from <italic toggle="yes">Garcinia bracteata</italic> Fruits

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00637




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[ASAP] Synthesis of Branched Monodisperse Oligoethylene Glycols and <sup>19</sup>F MRI-Traceable Biomaterials through Reductive Dimerization of Azides

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00331




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[ASAP] Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via <sup>15</sup>N Direct Detection Nuclear Magnetic Resonance

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00231




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[ASAP] Peptoid NPhe<sup>4</sup> in AGRP-Based c[Pro<sup>1</sup>-Arg<sup>2</sup>-Phe<sup>3</sup>-Phe<sup>4</sup>-Xxx<sup>5</sup>-Ala<sup>6</sup>-Phe<sup>7</sup>

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00641




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[ASAP] Synthesis and Evaluation of <sup>11</sup>C- and <sup>18</sup>F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00127




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[ASAP] Analysis of the Different Metabolic Phenotypes of Metalaxyl Enantiomers in Adolescent Rat by Using <sup>1</sup>H NMR Based Urinary Metabolomics

Chemical Research in Toxicology
DOI: 10.1021/acs.chemrestox.0c00011




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[ASAP] Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,<italic toggle="yes">N</italic><sup>6</sup>-Ethenoadenine in Strongly Positioned Nucleosome Core Particles

Chemical Research in Toxicology
DOI: 10.1021/acs.chemrestox.0c00089




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[ASAP] Quadruply Stranded Metallo-Supramolecular Helicate [Pd<sub>2</sub>(hextrz)<sub>4</sub>]<sup>4+</sup> Acts as a Molecular Mimic of Cytolytic Peptides

Chemical Research in Toxicology
DOI: 10.1021/acs.chemrestox.0c00061




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[ASAP] Study of the Influence of Resins on the Asphaltene Aggregates by <sup>1</sup>H DOSY NMR

Energy & Fuels
DOI: 10.1021/acs.energyfuels.0c00333




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[ASAP] <sup>13</sup>C NMR Relaxation Analysis of Protein GB3 for the Assessment of Side Chain Dynamics Predictions by Current AMBER and CHARMM Force Fields

Journal of Chemical Theory and Computation
DOI: 10.1021/acs.jctc.0c00050




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[ASAP] Enantioselective Copper-Catalyzed Remote C(sp<sup>3</sup>)–H Alkynylation of Linear Primary Sulfonamides

Organic Letters
DOI: 10.1021/acs.orglett.0c01325




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[ASAP] Structural Modulation of Electrically Conducting TCNQ Salts Using Na<sup>+</sup>(crown ether) Supramolecular Cations

Crystal Growth & Design
DOI: 10.1021/acs.cgd.0c00169




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[ASAP] Rare Earth Ion Encapsulated Basket-like {Gd?P<sub>6</sub>Mo<sup>V</sup><sub>2</sub>Mo<sup>VI</sup><sub>16</sub>O<sub>73</sub>} Cage as Efficient Electrochemical Sensor and Fluo

Crystal Growth & Design
DOI: 10.1021/acs.cgd.0c00211




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[ASAP] Trade-Offs between Speed, Accuracy, and Dissipation in tRNA<sup>Ile</sup> Aminoacylation

The Journal of Physical Chemistry Letters
DOI: 10.1021/acs.jpclett.0c01073




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[ASAP] A Systematic Evaluation of Antibody Modification and <sup>89</sup>Zr-Radiolabeling for Optimized Immuno-PET

Bioconjugate Chemistry
DOI: 10.1021/acs.bioconjchem.0c00087




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[ASAP] <sup>225</sup>Ac-H<sub>4</sub>py4pa for Targeted Alpha Therapy

Bioconjugate Chemistry
DOI: 10.1021/acs.bioconjchem.0c00171




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[ASAP] Trace Fe Incorporation into Ni-(oxy)hydroxide Stabilizes Ni<sup>3+</sup> Sites for Anodic Oxygen Evolution: A Double Thin-Layer Study

Langmuir
DOI: 10.1021/acs.langmuir.0c00264




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[ASAP] Base Catalytic Activity of [Nb<sub>10</sub>O<sub>28</sub>]<sup>6–</sup>: Effect of Countercations

The Journal of Physical Chemistry C
DOI: 10.1021/acs.jpcc.0c01488




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[ASAP] Tailoring Active O<sub>2</sub><sup>–</sup> and O<sub>2</sub><sup>2–</sup> Anions on a ZnO Surface with the Addition of Different Alkali Metals Probed by CO Oxidation

Industrial & Engineering Chemistry Research
DOI: 10.1021/acs.iecr.9b06863




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Happy 60<sup>th</sup> Anniversary, Morehead!

Celebrate Morehead's anniversary weekend with a special gift: See a planetarium show for $1.




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[ASAP] Structure- and Ligand-Based Virtual Screening on DUD-E<sup>+</sup>: Performance Dependence on Approximations to the Binding Pocket

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00115




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[ASAP] Transient Directing Group Enabled Pd-Catalyzed ?-C(sp<sup>3</sup>)–H Oxygenation of Alkyl Amines

ACS Catalysis
DOI: 10.1021/acscatal.0c01310




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[ASAP] Hydrogen/Deuterium and <sup>16</sup>O/<sup>18</sup>O-Exchange Mass Spectrometry Boosting the Reliability of Compound Identification

Analytical Chemistry
DOI: 10.1021/acs.analchem.9b05379




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[ASAP] Extraction of Individual Spectra from Mixture Data Based on High-Resolution <sup>13</sup>C–<sup>13</sup>C NMR Correlation Spectrum and DECODE Procedure

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00277




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[ASAP] Reaction Mechanism of the Isomerization of Monoterpene Epoxides with Fe<sup>3+</sup> as Active Catalytic Specie: A Computational Approach

The Journal of Physical Chemistry A
DOI: 10.1021/acs.jpca.9b09622




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[ASAP] Infrared Photodissociation Spectroscopy of Mass-Selected Cu<sub>2</sub>O<sub>2</sub>(CO)<sub><italic toggle="yes">n</italic></sub><sup>+</sup> Clusters in the Gas Phase

The Journal of Physical Chemistry A
DOI: 10.1021/acs.jpca.0c01813




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[ASAP] Computational Evidence for Homonuclear Ge<sup>I</sup>Ge<sup>I</sup> Dative Bonds

The Journal of Physical Chemistry A
DOI: 10.1021/acs.jpca.9b11665




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[ASAP] Low-Lying Electronic States of FeGe<italic toggle="yes"><sub>n</sub></italic><sup>–/0</sup> (<italic toggle="yes">n</italic> = 1–3) Clusters Calculated with Multireference Second-O

The Journal of Physical Chemistry A
DOI: 10.1021/acs.jpca.0c02521




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[ASAP] The First Quantitative Synthesis of a Closed Three-Link Chain (6<sub arrange="stack">1</sub><sup arrange="stack">3</sup>) Using Coordination and Noncovalent Interactions-Driven Self-Assembly

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c01406




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[ASAP] Eicosapentaenoic Acid-Enriched Phosphoethanolamine Plasmalogens Alleviated Atherosclerosis by Remodeling Gut Microbiota to Regulate Bile Acid Metabolism in LDLR<sup>–/–</sup> Mice

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.9b08296